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St. Louis

Cheap flights from Odessa, TX to St. Louis (STL)

MAF — STL
Jan 2 — Jan 91
Fri 1/2
Fri 1/9
1 adult, Economy
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Find flight deals from Odessa to St. Louis

Keep the following information in mind while searching for Odessa to St. Louis flight deals. Data was last updated December 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Popular in

July

Cheapest in

September

Average price

$382
Provider with most accurate pricing for Midland Intl-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Midland Intl-Lambert-St Louis flights.
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Highest demand for flights based on searches. 11% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated December 3, 2025.
See what other customers who have flown with Southwest from Odessa to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,253 reviews

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,253 reviews
Southwest
8.0
Very good
4,253 reviews

Overall

8.0

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Odessa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Odessa?

    Most people fly into Lambert-St Louis (STL) if they book a flight to St. Louis from Odessa. On average, Lambert-St Louis has 0 inbound flights from Odessa per day from 1 airline. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.

  • Can I find deals for flights from Odessa to St. Louis that include hotel bookings?

    Yes. In addition to deals on Odessa to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to St. Louis.

  • Can I find deals for business class flights from Odessa to St. Louis?

    Yes. Cheapflights offers flight deals from Odessa to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Swansea
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

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Alternative routes for Odessa to St. Louis

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Top airline flying from Odessa to St. Louis

Discover the top airline that operate flights from Odessa to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$196Average$376FlexibilityNo cancel feeOn-time63%

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