How long is the flight from Medford to St. Louis?

For as low as $274, Delta can have you in St. Louis from Medford in 15h 20m. There are 1712 mi between Medford and St. Louis.

What are the cheapest airlines flying from Medford to St. Louis round-trip?

Cheapflights users have booked flights from Medford to St. Louis round-trip from $192. Other airlines that can offer you cheap pricing are Alaska Airlines, from $303, and American Airlines, from $377. Delta is priced at 65% lower than the current average price of a flight leaving 3 months from now.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular airlines that fly from Medford to St. Louis?

The most popular airlines flying from Medford to St. Louis are United Airlines, Delta and American Airlines. Something to consider prior to booking your flight.

What is the cheapest time of day to fly from MFR to STL?

When flying from Medford to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on Medford-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Medford-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Medford-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Medford-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Medford to St. Louis that include hotel bookings?

Yes. In addition to deals on Medford to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Medford to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to St. Louis.

Can I find deals for business class flights from Medford to St. Louis?

Yes. Cheapflights offers flight deals from Medford to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$245+ Flights from Medford to St. Louis

Q: How much does it cost to fly round-trip from Medford to St. Louis?

Airfare is below average for this route at the moment. Medford to St. Louis flights typically cost between $561 and $757 in January. The cheapest round-trip price found within the last 3 days was $245 on Multiple Airlines (Jan 11-Jan 14).

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Find flight deals from Medford to St. Louis

Cheapest flights from Medford to St. Louis
Explore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Thu 12/411:40 amMFR - STL

2 stops11h 08mDelta

Sun 12/72:20 pmSTL - MFR

2 stops10h 42mDelta

Deal found 10/27

$294

Fri 11/2111:40 amMFR - STL

2 stops11h 06mDelta

Sun 11/236:40 amSTL - MFR

2 stops12h 03mDelta

Deal found 10/29

$315

Thu 12/45:45 amMFR - STL

1 stop6h 42mAlaska Airlines

Sun 12/77:00 amSTL - MFR

1 stop8h 16mAlaska Airlines

Deal found 10/27

$330

Fri 11/211:45 pmMFR - STL

1 stop8h 06mAmerican Airlines

Sun 11/232:29 pmSTL - MFR

1 stop7h 06mAmerican Airlines

Deal found 10/27

$350

Fri 11/213:35 pmMFR - STL

1 stop6h 19mAlaska Airlines

Sun 11/237:00 amSTL - MFR

1 stop19h 15mAlaska Airlines

Deal found 10/28

$394

Thu 12/251:36 pmMFR - STL

1 stop8h 23mAlaska Airlines

Fri 1/27:00 amSTL - MFR

1 stop9h 51mAlaska Airlines

Deal found 10/26

$478

Best flights from Medford to St. Louis
Discover carefully curated flight deals from Medford to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2025.

Sun 1/119:21 pmMFR - STL

1 stop17h 28mMultiple Airlines

Wed 1/147:43 pmSTL - MFR

2 stops26h 48mMultiple Airlines

Deal found 10/29

$245

Sat 1/106:05 amMFR - STL

2 stops15h 20mDelta

Tue 1/1311:23 amSTL - MFR

2 stops13h 56mDelta

Deal found 10/29

$274

Thu 12/45:45 amMFR - STL

1 stop6h 42mAlaska Airlines

Sun 12/77:00 amSTL - MFR

1 stop8h 16mAlaska Airlines

Deal found 10/27

$330

Thu 1/812:07 pmMFR - STL

2 stops9h 18mDelta

Wed 1/147:00 amSTL - MFR

2 stops11h 40mDelta

Deal found 10/29

$284

Fri 1/96:05 amMFR - STL

2 stops13h 30mDelta

Wed 1/146:35 amSTL - MFR

2 stops12h 05mDelta

Deal found 10/29

$284

Thu 12/411:40 amMFR - STL

2 stops11h 08mDelta

Sun 12/72:20 pmSTL - MFR

2 stops10h 42mDelta

Deal found 10/27

$294

Fri 11/2111:40 amMFR - STL

2 stops11h 06mDelta

Sun 11/236:40 amSTL - MFR

2 stops12h 03mDelta

Deal found 10/29

$315

Sun 1/1112:07 pmMFR - STL

2 stops9h 18mDelta

Wed 1/147:00 amSTL - MFR

2 stops11h 40mDelta

Deal found 10/29

$324

Tue 1/66:05 amMFR - STL

2 stops13h 30mDelta

Tue 1/135:00 pmSTL - MFR

1 stop7h 57mDelta

Deal found 10/29

$331

Tue 1/66:05 amMFR - STL

2 stops13h 30mDelta

Wed 1/145:00 pmSTL - MFR

1 stop7h 57mDelta

Deal found 10/29

$331

Fri 1/96:05 amMFR - STL

2 stops15h 20mDelta

Tue 1/135:00 pmSTL - MFR

1 stop7h 57mDelta

Deal found 10/29

$341

Fri 1/912:07 pmMFR - STL

2 stops9h 18mDelta

Mon 1/127:00 amSTL - MFR

1 stop7h 23mDelta

Deal found 10/27

$342

Last-minute flights from Medford to St. Louis
Discover last-minute flight deals from Medford to St. Louis. Data last updated October 29, 2025 and is based on user searches.

Sat 11/12:35 pmMFR - STL

1 stop23h 43mAlaska Airlines

Sat 11/87:00 amSTL - MFR

1 stop8h 55mAlaska Airlines

Deal found 10/29

$494

Sat 11/15:15 amMFR - STL

1 stop6h 24mDelta

Sat 11/86:50 amSTL - MFR

2 stops11h 54mDelta

Deal found 10/29

$500

Sat 11/16:00 amMFR - STL

2 stops8h 28mUnited Airlines

Sat 11/84:48 pmSTL - MFR

3 stops31h 42mUnited Airlines

Deal found 10/29

$814

Fri 11/2111:40 amMFR - STL

2 stops11h 06mDelta

Sun 11/236:40 amSTL - MFR

2 stops12h 03mDelta

Deal found 10/29

$315

Fri 11/211:45 pmMFR - STL

1 stop8h 06mAmerican Airlines

Sun 11/232:29 pmSTL - MFR

1 stop7h 06mAmerican Airlines

Deal found 10/27

$350

Fri 11/213:35 pmMFR - STL

1 stop6h 19mAlaska Airlines

Sun 11/237:00 amSTL - MFR

1 stop19h 15mAlaska Airlines

Deal found 10/28

$394

One-way flights from Medford to St. Louis
Search for one-way flight options from Medford to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 29, 2025.

Sat 11/155:20 amMFR - STL

1 stop6h 20mAmerican Airlines

Deal found 10/28

$248

Sat 11/158:48 amMFR - STL

2 stops21h 21mAlaska Airlines

Deal found 10/28

$308

Sat 11/1512:39 pmMFR - STL

3 stops51h 21mMultiple Airlines

Deal found 10/28

$405

Cheap flight deals from Medford to St. Louis

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$245 (Kiwi.com)
Popular in	March
Cheapest in	August
Average price	$540

Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.

Search Deals

From Medford to Lambert-St Louis

Search Deals

High demand for flights, 6% potential price rise

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in October 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sun 1/11

9:21 pm-4:49 pm

1 stop17h 28m

Lambert-St Louis

Wed 1/14

7:43 pm-8:31 pm

2 stops26h 48m

$245

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sat 1/10

6:05 am-11:25 pm

2 stops15h 20m

Lambert-St Louis

Tue 1/13

11:23 am-11:19 pm

2 stops13h 56m

$274

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Thu 1/8

12:07 pm-11:25 pm

2 stops9h 18m

Lambert-St Louis

Wed 1/14

7:00 am-4:40 pm

2 stops11h 40m

$284

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Fri 1/9

6:05 am-9:35 pm

2 stops13h 30m

Lambert-St Louis

Wed 1/14

6:35 am-4:40 pm

2 stops12h 05m

$284

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Thu 12/4

11:40 am-12:48 am

2 stops11h 08m

Lambert-St Louis

Sun 12/7

2:20 pm-11:02 pm

2 stops10h 42m

$294

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Fri 11/21

11:40 am-12:46 am

2 stops11h 06m

Lambert-St Louis

Sun 11/23

6:40 am-4:43 pm

2 stops12h 03m

$315

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sun 1/11

12:07 pm-11:25 pm

2 stops9h 18m

Lambert-St Louis

Wed 1/14

7:00 am-4:40 pm

2 stops11h 40m

$324

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Thu 12/4

5:45 am-2:27 pm

1 stop6h 42m

Lambert-St Louis

Sun 12/7

7:00 am-1:16 pm

1 stop8h 16m

$330

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 1/6

6:05 am-9:35 pm

2 stops13h 30m

Lambert-St Louis

Tue 1/13

5:00 pm-10:57 pm

1 stop7h 57m

$331

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 1/6

6:05 am-9:35 pm

2 stops13h 30m

Lambert-St Louis

Wed 1/14

5:00 pm-10:57 pm

1 stop7h 57m

$331

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 15 results

Compare providers for flights from Medford to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to St. Louis in October.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Medford-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Medford-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Medford-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Medford-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Medford to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Medford with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to St. Louis

What is the cheapest month to book a flight from Medford to St. Louis?

Currently, April is the cheapest month in which you can book a flight from Medford to St. Louis (average of $191). Flying from Medford to St. Louis in June is currently the most expensive (average of $543). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Medford to St. Louis?

Reviews of airlines servicing St. Louis

Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

11,211 reviews

Reviews

1 / 20

10.0

Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.

Alaska Airlines

8.0

Very good

11,211 reviews

Alaska Airlines

8.0

Very good

11,211 reviews

Reviews

1 / 20

10.0

Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.

Delta

7.9

Good

7,992 reviews

Alaska Airlines

8.0

Very good

11,211 reviews

Reviews

1 / 20

10.0

Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.

United Airlines

7.4

Good

8,999 reviews

Alaska Airlines

8.0

Very good

11,211 reviews

Reviews

1 / 20

10.0

Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.

American Airlines

7.2

Good

11,032 reviews

Alaska Airlines

8.0

Very good

11,211 reviews

Reviews

1 / 20

10.0

Excellent

Anonymous,Sep 2025

BOS - HNL

The flight was awesome but a little long. I would prefer a flight with a layover. The amount of space available was minimal and a little uncomfortable for that long of a flight.

Related info for your journey

How long is the flight from Medford to St. Louis?
For as low as $274, Delta can have you in St. Louis from Medford in 15h 20m. There are 1712 mi between Medford and St. Louis.
What are the cheapest airlines flying from Medford to St. Louis round-trip?
Cheapflights users have booked flights from Medford to St. Louis round-trip from $192. Other airlines that can offer you cheap pricing are Alaska Airlines, from $303, and American Airlines, from $377. Delta is priced at 65% lower than the current average price of a flight leaving 3 months from now.
Can I find deals for flights from Medford to St. Louis that include hotel bookings?
Yes. In addition to deals on Medford to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Medford to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to St. Louis.
Can I find deals for business class flights from Medford to St. Louis?
Yes. Cheapflights offers flight deals from Medford to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Medford to St. Louis?
Currently, April is the cheapest month in which you can book a flight from Medford to St. Louis (average of $191). Flying from Medford to St. Louis in June is currently the most expensive (average of $543). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Edwardsville

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St. Peters

Chesterfield

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Farmington

Festus

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Alternative routes for Medford to St. Louis

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Other flights to St. Louis

Top 4 airlines flying from Medford to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$192	Average$512	FlexibilityNo cancel fee	On-timeN/A
Alaska Airlines	Cheapest$303	Average$427	FlexibilityNo cancel fee	On-time75%
American Airlines	Cheapest$377	Average$411	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$427	Average$582	FlexibilityNo cancel fee	On-time69%

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$245+ Cheap flights from Medford to St. Louis (MFR - STL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Medford to St. Louis with Cheapflights

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3. Compare prices and book

Find flight deals from Medford to St. Louis

Cheapest flights from Medford to St. LouisExplore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Explore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Cheap flight deals from Medford to St. Louis

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Medford to St. Louis that are best for you.

Compare providers for flights from Medford to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to St. Louis in October.

Best time to book a flight from Medford to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Medford with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Medford to St. Louis

What is the cheapest month to book a flight from Medford to St. Louis?

How much does it cost to fly round-trip from Medford to St. Louis?

Reviews of airlines servicing St. Louis

Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and United Airlines from Medford to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Medford to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Medford to St. Louis?

What are the cheapest airlines flying from Medford to St. Louis round-trip?

Can I find deals for flights from Medford to St. Louis that include hotel bookings?

How can I find direct flights from Medford to St. Louis?

Can I find deals for business class flights from Medford to St. Louis?

What is the cheapest month to book a flight from Medford to St. Louis?

Traveling to a place near St. Louis?

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Top 4 airlines flying from Medford to St. Louis

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Cheapest flights from Medford to St. Louis
Explore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.