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$139+ Cheap flights from Medford to St. Louis (MFR - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Medford to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$371
(Delta)

One-way from

$139
(Hawaiian Airlines)

Popular in

March

Cheapest in

October

Average price

$533
From Medford to Lambert-St Louis
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One-way flight from Medford to Lambert-St Louis
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High demand for flights, 3% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Medford to St. Louis

Cheapest flights from Medford to St. Louis
Explore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:15 amMFR - STL
1 stop6h 29mDelta
Mon 9/222:31 pmSTL - MFR
2 stops10h 19mDelta
Deal found 7/28$371
This Hawaiian Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Hawaiian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:43 amMFR - STL
1 stop6h 56mHawaiian Airlines
Mon 9/226:30 pmSTL - MFR
1 stop8h 03mHawaiian Airlines
Deal found 7/28$379
This Alaska Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/235:14 amMFR - STL
2 stops16h 49mAlaska Airlines
Sun 10/267:00 amSTL - MFR
1 stop8h 58mAlaska Airlines
Deal found 7/26$445
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/121:00 pmMFR - STL
1 stop5h 45mUnited Airlines
Sat 8/165:41 pmSTL - MFR
1 stop7h 00mUnited Airlines
Deal found 7/28$456
This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/119:03 pmMFR - STL
3 stops13h 07mMultiple Airlines
Thu 8/142:30 pmSTL - MFR
3 stops25h 16mMultiple Airlines
Deal found 7/28$512
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/151:52 pmMFR - STL
1 stop8h 24mAmerican Airlines
Sun 8/176:14 pmSTL - MFR
1 stop7h 03mAmerican Airlines
Deal found 7/28$529

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Medford to St. Louis that are best for you.

Fly from

Medford

Fly to

St. Louis

Route

Depart

Return

Price

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sat 9/13

5:15 am-1:44 pm

1 stop6h 29m

Lambert-St Louis

Mon 9/22

2:31 pm-10:50 pm

2 stops10h 19m

$371

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sat 9/13

5:43 am-2:39 pm

1 stop6h 56m

Lambert-St Louis

Mon 9/22

6:30 pm-12:33 am

1 stop8h 03m

$379

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Thu 10/23

5:14 am-12:03 am

2 stops16h 49m

Lambert-St Louis

Sun 10/26

7:00 am-1:58 pm

1 stop8h 58m

$445

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 8/12

1:00 pm-8:45 pm

1 stop5h 45m

Lambert-St Louis

Sat 8/16

5:41 pm-10:41 pm

1 stop7h 00m

$456

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Mon 8/11

9:03 pm-12:10 pm

3 stops13h 07m

Lambert-St Louis

Thu 8/14

2:30 pm-1:46 pm

3 stops25h 16m

$512

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Fri 8/15

1:52 pm-12:16 am

1 stop8h 24m

Lambert-St Louis

Sun 8/17

6:14 pm-11:17 pm

1 stop7h 03m

$529

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Wed 10/8

2:41 pm-12:03 am

1 stop7h 22m

$139

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Wed 10/8

11:35 am-12:24 am

2 stops10h 49m

$167

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Sun 8/24

5:47 pm-11:59 pm

1 stop28h 12m

$223

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 8/12

1:52 pm-12:16 am

1 stop8h 24m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 12 results
1
2

Best time to book a flight from Medford to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to St. Louis

What is the cheapest month to book a flight from Medford to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Medford to St. Louis (average of $311). Flying from Medford to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to STL?

Find hourly flight availability from Medford to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

It’s optimal to fly from Medford to St. Louis at noon. By choosing this option you can save up to 5% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 29, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta, and Hawaiian Airlines from Medford to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Overall

8.0

Food

7.1

Comfort

7.8

Entertainment

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Overall

8.0

Food

7.1

Comfort

7.8

Entertainment

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Delta
8.0
Very good
7,979 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Overall

8.0

Food

7.1

Comfort

7.8

Entertainment

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Hawaiian Airlines
7.8
Good
2,605 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Overall

8.0

Food

7.1

Comfort

7.8

Entertainment

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
United Airlines
7.4
Good
8,896 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Overall

8.0

Food

7.1

Comfort

7.8

Entertainment

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Crew

8.5

Overall

8.0

Food

7.1

Comfort

7.8

Entertainment

7.1

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.

Related info for your journey

Find useful and relevant information for your journey from Medford to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Medford to St. Louis round-trip?

    Cheapflights users have booked flights from Medford to St. Louis round-trip from $371. Other airlines that can offer you cheap pricing are Hawaiian Airlines, from $379, and Alaska Airlines, from $445. Delta is priced at 30% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Medford to St. Louis one-way?

    To fly one-way, consider booking your trip with Hawaiian Airlines, which is currently one of the cheapest options available, starting at $139. Delta flights start at $167 while deals on Alaska Airlines start at $223 one-way.

  • Can I find deals for flights from Medford to St. Louis that include hotel bookings?

    Yes. In addition to deals on Medford to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to St. Louis.

  • Can I find deals for business class flights from Medford to St. Louis?

    Yes. Cheapflights offers flight deals from Medford to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Medford to St. Louis (average of $311). Flying from Medford to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
O'Fallon
Maryland Heights
Fairview Heights
Collinsville
Eureka
St. Peters
Glencoe
Alton
Chesterfield
Festus
Farmington

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Top 4 airlines flying from Medford to St. Louis

Discover the top 4 airlines that operate flights from Medford to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$192Average$448FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$303Average$495FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$368Average$463FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$379Average$603FlexibilityNo cancel feeOn-time69%

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