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$139+ Cheap flights from Medford to St. Louis (MFR - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Medford to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$320
(Alaska Airlines)

One-way from

$139
(Alaska Airlines)

Popular in

March

Cheapest in

October

Average price

$598
From Medford to Lambert-St Louis
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One-way flight from Medford to Lambert-St Louis
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High demand for flights, 4% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Medford to St. Louis

Cheapest flights from Medford to St. Louis
Explore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Alaska Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/77:44 pmMFR - STL
1 stop17h 11mAlaska Airlines
Sat 10/183:57 pmSTL - MFR
1 stop10h 25mAlaska Airlines
Deal found 6/11$320
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/91:00 pmMFR - STL
1 stop6h 50mUnited Airlines
Sat 7/196:00 amSTL - MFR
1 stop7h 52mUnited Airlines
Deal found 6/11$418
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2611:23 amMFR - STL
2 stops11h 14mDelta
Mon 12/16:59 pmSTL - MFR
1 stop6h 45mDelta
Deal found 6/10$602

Cheapflights Fare Finder

Customize your flight search to find flights from Medford to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Medford to St. Louis that are best for you.

Fly from

Medford

Fly to

St. Louis

Route

Depart

Return

Price

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 10/7

7:44 pm-2:55 pm

1 stop17h 11m

Lambert-St Louis

Sat 10/18

3:57 pm-12:22 am

1 stop10h 25m

$320

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Wed 7/9

1:00 pm-9:50 pm

1 stop6h 50m

Lambert-St Louis

Sat 7/19

6:00 am-11:52 am

1 stop7h 52m

$418

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Wed 11/26

11:23 am-12:37 am

2 stops11h 14m

Lambert-St Louis

Mon 12/1

6:59 pm-11:44 pm

1 stop6h 45m

$602

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 10/7

2:41 pm-11:59 pm

1 stop7h 18m

$139

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 8/12

1:52 pm-12:16 am

1 stop8h 24m

$140

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Tue 10/7

6:37 pm-10:49 am

2 stops14h 12m

$190

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Thu 7/10

4:11 pm-9:52 am

3 stops15h 41m

$213

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Best time to book a flight from Medford to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to St. Louis

What is the cheapest month to book a flight from Medford to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Medford to St. Louis (average of $311). Flying from Medford to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MFR to STL?

Find hourly flight availability from Medford to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

It’s optimal to fly from Medford to St. Louis at noon. By choosing this option you can save up to 5% on the cost of your flight, compared to a flight in the afternoon.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated June 12, 2025.
Read reviews from past customers who have flown Alaska Airlines, Delta and United Airlines from Medford to St. Louis. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Entertainment

7.1

Overall

8.0

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Entertainment

7.1

Overall

8.0

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,950 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Entertainment

7.1

Overall

8.0

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Entertainment

7.1

Overall

8.0

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Boarding

8.1

Entertainment

7.1

Overall

8.0

Comfort

7.8

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Medford to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Medford to St. Louis round-trip?

    Cheapflights users have booked flights from Medford to St. Louis round-trip from $320. Other airlines that can offer you cheap pricing are United Airlines, from $418, and Delta, from $602. Alaska Airlines is priced at 40% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Medford to St. Louis one-way?

    To fly one-way, consider booking your trip with Alaska Airlines, which is currently one of the cheapest options available, starting at $139. American Airlines flights start at $140 while deals on United Airlines start at $190 one-way.

  • Can I find deals for flights from Medford to St. Louis that include hotel bookings?

    Yes. In addition to deals on Medford to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to St. Louis.

  • Can I find deals for business class flights from Medford to St. Louis?

    Yes. Cheapflights offers flight deals from Medford to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Medford to St. Louis (average of $311). Flying from Medford to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Medford?

Book flights to Medford if you plan to visit one of these locations
O'Fallon
Maryland Heights
Fairview Heights
Collinsville
Eureka
St. Peters
Glencoe
Festus
Alton
Farmington

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Top 4 airlines flying from Medford to St. Louis

Discover the top 4 airlines that operate flights from Medford to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$192Average$448FlexibilityNo cancel feeOn-timeN/A
Alaska AirlinesCheapest$303Average$482FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$368Average$463FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$379Average$587FlexibilityNo cancel feeOn-time69%

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