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$352+ Cheap flights from Medford to St. Louis (MFR - STL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Medford to St. Louis

Cheapest flights from Medford to St. Louis
Explore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:00 amMFR - STL
1 stop6h 20mUnited Airlines
Mon 12/226:41 amSTL - MFR
1 stop7h 27mUnited Airlines
Deal found 12/10$1,326
This Alaska Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/183:28 pmMFR - STL
1 stop6h 31mAlaska Airlines
Mon 12/227:00 amSTL - MFR
2 stops10h 10mAlaska Airlines
Deal found 12/10$1,484

Find flight deals from Medford to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$352
(Alaska Airlines)

Popular in

December

Cheapest in

August

Average price

$973
Provider with most accurate pricing for Medford-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Medford-Lambert-St Louis flights.
Search Deals
From Medford to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 31% potential increase in price ($258 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($38 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Medford to St. Louis that are best for you.

Fly from

Medford

Fly to

St. Louis

Route

Depart

Return

Price

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Thu 1/29

5:42 am-1:54 pm

1 stop6h 12m

Lambert-St Louis

Sat 1/31

6:19 pm-11:56 pm

1 stop7h 37m

$352

MedfordSt. Louis

MFR - STL

MFRSTL

Medford

Mon 5/4

12:30 pm-12:36 am

2 stops10h 06m

Lambert-St Louis

Sun 5/10

6:59 pm-11:41 pm

1 stop6h 42m

$502

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Compare providers for flights from Medford to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to St. Louis in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Medford-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Medford-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Medford-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medford-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Medford to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to St. Louis

What is the cheapest month to book a flight from Medford to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Medford to St. Louis (average of $178). Flying from Medford to St. Louis in December is currently the most expensive (average of $973). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated December 12, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Medford to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Medford to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Medford to St. Louis?

    For as low as $352, Alaska Airlines can have you in St. Louis from Medford in 6h 12m. There are 1712 mi between Medford and St. Louis.

  • What are the cheapest airlines flying from Medford to St. Louis round-trip?

    Cheapflights users have booked flights from Medford to St. Louis round-trip from $178. Other airlines that can offer you cheap pricing are American Airlines, from $377, and United Airlines, from $427. Delta is priced at 68% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Medford to St. Louis that include hotel bookings?

    Yes. In addition to deals on Medford to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to St. Louis.

  • Can I find deals for business class flights from Medford to St. Louis?

    Yes. Cheapflights offers flight deals from Medford to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Medford to St. Louis (average of $178). Flying from Medford to St. Louis in December is currently the most expensive (average of $973). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Swansea
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

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Top 3 airlines flying from Medford to St. Louis

Discover the top 3 airlines that operate flights from Medford to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$192Average$483FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$377Average$411FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$427Average$567FlexibilityNo cancel feeOn-time69%

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