$196+ Cheap flights from Medford to St. Louis (MFR - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — STL
Apr 10 — Apr 171
Round-trip
1 adult, Economy
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Find cheap flights from Medford to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Medford to St. LouisExplore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
Explore the most affordable flight options available from Medford to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
This Alaska Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:45 am
MFR
- STL
1 stop16h 14m
Alaska Airlines
Wed 4/157:00 am
STL
- MFR
1 stop7h 45m
Alaska Airlines
Deal found 3/8![Alaska Airlines logo]()
$326
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:14 am
MFR
- STL
2 stops11h 11m
Delta
Sat 4/255:00 pm
STL
- MFR
1 stop7h 39m
Delta
Deal found 3/9![Delta logo]()
$328
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:31 pm
MFR
- STL
2 stops11h 54m
United Airlines
Sat 4/259:16 am
STL
- MFR
2 stops14h 21m
United Airlines
Deal found 3/9![United Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:00 am
MFR
- STL
1 stop6h 17m
Delta
Mon 4/136:45 pm
STL
- MFR
1 stop7h 07m
Delta
Deal found 3/10![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:50 pm
MFR
- STL
1 stop6h 04m
United Airlines
Wed 4/159:10 am
STL
- MFR
2 stops14h 27m
United Airlines
Deal found 3/8![United Airlines logo]()
$372
This Alaska Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:50 pm
MFR
- STL
1 stop26h 09m
Alaska Airlines
Sat 4/257:00 am
STL
- MFR
1 stop7h 52m
Alaska Airlines
Deal found 3/9![Alaska Airlines logo]()
$382
This Expedia deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:11 pm
MFR
- STL
1 stop22h 26m
Alaska Airlines
Mon 6/152:53 pm
STL
- MFR
1 stop11h 11m
Alaska Airlines
Deal found 3/10![Alaska Airlines logo]()
$384
Best flights from Medford to St. LouisDiscover carefully curated flight deals from Medford to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
Discover carefully curated flight deals from Medford to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
This Alaska Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:45 am
MFR
- STL
1 stop16h 14m
Alaska Airlines
Wed 4/157:00 am
STL
- MFR
1 stop7h 45m
Alaska Airlines
Deal found 3/6![Alaska Airlines logo]()
$326
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:00 am
MFR
- STL
1 stop6h 17m
Delta
Mon 4/136:45 pm
STL
- MFR
1 stop7h 07m
Delta
Deal found 3/10![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:31 pm
MFR
- STL
2 stops11h 54m
United Airlines
Wed 4/152:40 pm
STL
- MFR
1 stop8h 57m
United Airlines
Deal found 3/6![United Airlines logo]()
$372
Last-minute flights from Medford to St. LouisDiscover last-minute flight deals from Medford to St. Louis. Data last updated March 11, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to St. Louis. Data last updated March 11, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:00 am
MFR
- STL
1 stop6h 17m
Delta
Mon 4/136:45 pm
STL
- MFR
1 stop7h 07m
Delta
Deal found 3/10![Delta logo]()
$349
This Alaska Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:45 am
MFR
- STL
1 stop16h 14m
Alaska Airlines
Wed 4/157:00 am
STL
- MFR
1 stop7h 45m
Alaska Airlines
Deal found 3/8![Alaska Airlines logo]()
$326
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:50 pm
MFR
- STL
1 stop6h 04m
United Airlines
Wed 4/159:10 am
STL
- MFR
2 stops14h 27m
United Airlines
Deal found 3/8![United Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:14 am
MFR
- STL
2 stops11h 11m
Delta
Sat 4/255:00 pm
STL
- MFR
1 stop7h 39m
Delta
Deal found 3/9![Delta logo]()
$328
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:31 pm
MFR
- STL
2 stops11h 54m
United Airlines
Sat 4/259:16 am
STL
- MFR
2 stops14h 21m
United Airlines
Deal found 3/9![United Airlines logo]()
$333
This Alaska Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:50 pm
MFR
- STL
1 stop26h 09m
Alaska Airlines
Sat 4/257:00 am
STL
- MFR
1 stop7h 52m
Alaska Airlines
Deal found 3/9![Alaska Airlines logo]()
$382
One-way flights from Medford to St. LouisSearch for one-way flight options from Medford to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
Search for one-way flight options from Medford to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:31 pm
MFR
- STL
2 stops11h 54m
United Airlines
Deal found 3/7![United Airlines logo]()
$196
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/265:10 am
MFR
- STL
1 stop6h 13m
Delta
Deal found 3/7![Delta logo]()
$260
Find flight deals from Medford to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $326 (Alaska Airlines) |
One-way from | $196 (United Airlines) |
Popular in | December |
Cheapest in | August |
Average price | $438 |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Medford to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Tue 4/14
5:45 am-11:59 pm
1 stop16h 14m
Lambert-St Louis
Wed 4/15
7:00 am-12:45 pm
1 stop7h 45m
$326
Quickest round-trip
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Thu 4/9
5:00 am-1:17 pm
1 stop6h 17m
Lambert-St Louis
Mon 4/13
6:45 pm-11:52 pm
1 stop7h 07m
$349
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Tue 4/14
6:31 pm-8:25 am
2 stops11h 54m
Lambert-St Louis
Wed 4/15
2:40 pm-9:37 pm
1 stop8h 57m
$372
Cheapest one-way
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Sun 4/26
6:31 pm-8:25 am
2 stops11h 54m
$196
Quickest one-way
MedfordSt. Louis
MFR - STL
MFRSTL
Medford
Sun 4/26
5:10 am-1:23 pm
1 stop6h 13m
$260
Sorted by cheapest first
Compare providers for flights from Medford to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to St. Louis in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Medford with our price prediction graph.
MFR-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated March 11, 2026.
Peruse reviews from past customers who have flown with Delta and United Airlines from Medford to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.9
Overall
7.9
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Overall
7.9
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Comfort
7.9
Overall
7.9
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Medford to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Medford and St. Louis flights
Browse other Medford and St. Louis flight options. Last updated on March 11, 2026.
Other flights from Medford
Browse through other flights departing from Medford. Flights are based on user searches made on Cheapflights and were last updated on March 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 11, 2026.
Top 2 airlines flying from Medford to St. Louis
Discover the top 2 airlines that operate flights from Medford to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$178 | Average$483 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$437 | Average$540 | FlexibilityNo cancel fee | On-time69% |