How popular is this Key Largo to St. Louis flight route?

Flights from Key Largo to Lambert-St Louis have been viewed 13 times in the past calendar month.

How long is the flight from Key Largo to St. Louis?

Airlines like American Airlines and Frontier fly from Key Largo to St. Louis in about 3h 08m. The time it takes to get you to your destination can typically vary by up to 2h 02m. The distance from Key Largo to St. Louis is about 1069 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines to fly from Key Largo to St. Louis one-way?

To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $49. Frontier flights start at $69 while deals on Delta start at $98 one-way.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the cheapest flights from Key Largo to St. Louis?

Looking at all options, your cheapest flight can be booked for $89. While the most popular route (Miami - Lambert-St Louis) can be booked for $128 on average, our data indicates $347 when flying from Key Largo to St. Louis.

What are the most reliable airlines from Key Largo to St. Louis?

Before booking your flight to St. Louis from Key Largo, check out the most reliable airlines to get you to your destination on time: Envoy Air (86%), Qatar Airways (84%), Royal Air Maroc( 80%).

What are the most popular airlines that fly from Key Largo to St. Louis?

Consider American Airlines, Southwest or Spirit Airlines when booking your flight. These represent the most popular airlines when flying from Key Largo to St. Louis.

What airport do you fly into for flights to St. Louis from Key Largo?

If you book a flight to St. Louis from Key Largo, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis. There are 3 flights from Key Largo to Lambert-St Louis per day from 5 different airlines.

Can I find deals for flights from Key Largo to St. Louis that include hotel bookings?

Yes. In addition to deals on Key Largo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Key Largo to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to St. Louis.

Can I find deals for business class flights from Key Largo to St. Louis?

Yes. Cheapflights offers flight deals from Key Largo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$59+ Flights from Key Largo to St. Louis

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Find cheap flights from Key Largo to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Key Largo to Lambert-St Louis are usually found in October or August, booked 62 days in advance, depart on a Thursday or Friday and return on a Sunday

Cheap flight deals from Key Largo to St. Louis

Cheapest flights from Key Largo to St. Louis
Explore the most affordable flight options available from Key Largo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Wed 12/318:00 amMIA - STL

1 stop26h 40mMultiple Airlines

Wed 1/75:11 pmSTL - MIA

2 stops25h 35mMultiple Airlines

Deal found 12/17

$193

Tue 12/305:30 amMIA - STL

1 stop5h 10mFrontier

Mon 1/57:43 pmSTL - MIA

1 stop8h 17mFrontier

Deal found 12/16

$203

Wed 12/318:00 amMIA - STL

1 stop26h 40mMultiple Airlines

Sun 1/410:57 amSTL - MIA

1 stop25h 09mMultiple Airlines

Deal found 12/17

$206

Tue 12/305:30 amMIA - STL

1 stop5h 10mMultiple Airlines

Tue 1/65:11 pmSTL - MIA

2 stops18h 55mMultiple Airlines

Deal found 12/16

$215

Wed 12/249:05 pmMIA - STL

1 stop13h 35mMultiple Airlines

Mon 1/54:27 pmSTL - MIA

2 stops43h 39mMultiple Airlines

Deal found 12/15

$220

Tue 12/305:30 amMIA - STL

1 stop5h 10mMultiple Airlines

Sun 1/410:57 amSTL - MIA

1 stop25h 09mMultiple Airlines

Deal found 12/16

$222

Tue 12/305:30 amMIA - STL

1 stop5h 10mFrontier

Thu 1/110:42 amSTL - MIA

1 stop7h 48mFrontier

Deal found 12/16

$224

Mon 12/2910:19 pmMIA - STL

1 stop12h 21mMultiple Airlines

Tue 1/65:11 pmSTL - MIA

2 stops18h 55mMultiple Airlines

Deal found 12/17

$225

Thu 12/255:30 amMIA - STL

1 stop5h 10mFrontier

Mon 1/57:43 pmSTL - MIA

1 stop8h 17mFrontier

Deal found 12/17

$228

Best flights from Key Largo to St. Louis
Discover carefully curated flight deals from Key Largo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Sun 2/15:30 amMIA - STL

1 stop26h 21mMultiple Airlines

Sun 2/88:59 amSTL - MIA

2 stops25h 57mMultiple Airlines

Deal found 12/16

$176

Wed 1/77:00 amMIA - STL

Nonstop3h 08mAmerican Airlines

Wed 1/711:05 amSTL - MIA

1 stop8h 15mAmerican Airlines

Deal found 12/17

$252

Tue 12/305:30 amMIA - STL

1 stop5h 10mFrontier

Wed 1/77:43 pmSTL - MIA

1 stop15h 14mFrontier

Deal found 12/17

$258

Wed 12/313:01 pmMIA - STL

1 stop5h 03mDelta

Wed 1/79:59 amSTL - MIA

1 stop10h 42mDelta

Deal found 12/16

$281

Mon 2/95:10 pmMIA - STL

1 stop6h 30mSouthwest

Tue 2/177:50 amSTL - MIA

Nonstop2h 40mSouthwest

Deal found 12/16

$329

Tue 12/305:30 amMIA - STL

1 stop5h 10mMultiple Airlines

Mon 1/510:10 pmSTL - MIA

2 stops34h 05mMultiple Airlines

Deal found 12/17

$247

Tue 2/107:00 amMIA - STL

Nonstop3h 08mAmerican Airlines

Tue 2/2411:19 amSTL - MIA

Nonstop2h 50mAmerican Airlines

Deal found 12/16

$289

Sun 12/285:30 amMIA - STL

1 stop5h 10mMultiple Airlines

Wed 1/75:11 pmSTL - MIA

2 stops25h 35mMultiple Airlines

Deal found 12/17

$265

Wed 12/318:45 amMIA - STL

1 stop4h 36mDelta

Thu 1/19:47 amSTL - MIA

1 stop5h 09mDelta

Deal found 12/17

$303

Sun 1/189:11 amMIA - STL

1 stop6h 46mAmerican Airlines

Fri 1/236:02 pmSTL - MIA

Nonstop2h 58mAmerican Airlines

Deal found 12/16

$326

Last-minute flights from Key Largo to St. Louis
Discover last-minute flight deals from Key Largo to St. Louis. Data last updated December 18, 2025 and is based on user searches.

Wed 12/249:05 pmMIA - STL

1 stop13h 35mMultiple Airlines

Mon 1/54:27 pmSTL - MIA

2 stops43h 39mMultiple Airlines

Deal found 12/15

$220

Tue 12/305:30 amMIA - STL

1 stop5h 10mFrontier

Mon 1/57:43 pmSTL - MIA

1 stop8h 17mFrontier

Deal found 12/16

$203

Tue 12/305:30 amMIA - STL

1 stop5h 10mMultiple Airlines

Tue 1/65:11 pmSTL - MIA

2 stops18h 55mMultiple Airlines

Deal found 12/16

$215

Wed 12/318:00 amMIA - STL

1 stop26h 40mMultiple Airlines

Wed 1/75:11 pmSTL - MIA

2 stops25h 35mMultiple Airlines

Deal found 12/17

$193

Wed 12/318:00 amMIA - STL

1 stop26h 40mMultiple Airlines

Sun 1/410:57 amSTL - MIA

1 stop25h 09mMultiple Airlines

Deal found 12/17

$206

Thu 1/87:00 amMIA - STL

1 stop8h 48mMultiple Airlines

Mon 1/125:11 pmSTL - MIA

2 stops17h 45mMultiple Airlines

Deal found 12/17

$155

Fri 1/167:09 pmMIA - STL

1 stop12h 42mMultiple Airlines

Mon 1/198:32 pmSTL - MIA

1 stop14h 24mMultiple Airlines

Deal found 12/17

$128

Fri 1/165:09 pmMIA - STL

1 stop14h 42mFrontier

Sun 1/185:11 pmSTL - MIA

2 stops17h 28mFrontier

Deal found 12/17

$174

Fri 1/167:09 pmMIA - STL

1 stop12h 42mFrontier

Mon 1/198:32 pmSTL - MIA

2 stops20h 22mFrontier

Deal found 12/17

$175

Sun 1/187:00 amMIA - STL

1 stop24h 51mMultiple Airlines

Fri 1/237:39 pmSTL - MIA

1 stop20h 33mMultiple Airlines

Deal found 12/16

$173

One-way flights from Key Largo to St. Louis
Search for one-way flight options from Key Largo to St. Louis. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Thu 1/87:00 amMIA - STL

1 stop8h 48mMultiple Airlines

Deal found 12/16

$59

Tue 2/175:05 amMIA - STL

1 stop26h 46mFrontier

Deal found 12/16

$62

Fri 1/167:09 pmMIA - STL

1 stop12h 42mFrontier

Deal found 12/16

$63

Tue 1/137:00 amMIA - STL

1 stop24h 51mMultiple Airlines

Deal found 12/16

$64

Wed 1/77:09 pmMIA - STL

1 stop20h 39mFrontier

Deal found 12/16

$66

Fri 2/137:09 pmMIA - STL

1 stop12h 42mFrontier

Deal found 12/15

$69

Sun 3/17:09 pmMIA - STL

1 stop12h 42mFrontier

Deal found 12/17

$70

Sun 2/85:30 amMIA - STL

1 stop26h 21mFrontier

Deal found 12/17

$72

Fri 2/207:05 amMIA - STL

1 stop24h 46mMultiple Airlines

Deal found 12/17

$76

Sun 1/187:00 amMIA - STL

1 stop24h 51mMultiple Airlines

Deal found 12/16

$77

Find flight deals from Key Largo to St. Louis

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$126 (Kiwi.com)
One-way from	$59 (Trip.com)
Popular in	March
Cheapest in	October
Average price	$356

Provider with most accurate pricing for Miami-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Miami-Lambert-St Louis flights.

Search Deals

From Key Largo to Lambert-St Louis

Search Deals

One-way flight from Key Largo to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 18% potential increase in price ($82 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Key Largo to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MiamiSt. Louis

MIA - STL

MIASTL

Miami

Sun 2/1

5:30 am-6:51 am

1 stop26h 21m

Lambert-St Louis

Sun 2/8

8:59 am-11:56 am

2 stops25h 57m

$176

MiamiSt. Louis

MIA - STL

MIASTL

Miami

Tue 12/30

5:30 am-9:40 am

1 stop5h 10m

Lambert-St Louis

Mon 1/5

10:10 pm-9:15 am

2 stops34h 05m

$247

MiamiSt. Louis

MIA - STL

MIASTL

Miami

Wed 1/7

7:00 am-9:08 am

Nonstop3h 08m

Lambert-St Louis

Wed 1/7

11:05 am-8:20 pm

1 stop8h 15m

$252

MiamiSt. Louis

MIA - STL

MIASTL

Miami

Tue 12/30

5:30 am-9:40 am

1 stop5h 10m

Lambert-St Louis

Wed 1/7

7:43 pm-11:57 am

1 stop15h 14m

$258

MiamiSt. Louis

MIA - STL

MIASTL

Miami

Sun 12/28

5:30 am-9:40 am

1 stop5h 10m

Lambert-St Louis

Wed 1/7

5:11 pm-7:46 pm

2 stops25h 35m

$265

MiamiSt. Louis

MIA - STL

MIASTL

Miami

Wed 12/31

3:01 pm-7:04 pm

1 stop5h 03m

Lambert-St Louis

Wed 1/7

9:59 am-9:41 pm

1 stop10h 42m

$281

MiamiSt. Louis

MIA - STL

MIASTL

Miami

Tue 2/10

7:00 am-9:08 am

Nonstop3h 08m

Lambert-St Louis

Tue 2/24

11:19 am-3:09 pm

Nonstop2h 50m

$289

MiamiSt. Louis

MIA - STL

MIASTL

Miami

Wed 12/31

8:45 am-12:21 pm

1 stop4h 36m

Lambert-St Louis

Thu 1/1

9:47 am-3:56 pm

1 stop5h 09m

$303

MiamiSt. Louis

MIA - STL

MIASTL

Miami

Sun 1/18

9:11 am-2:57 pm

1 stop6h 46m

Lambert-St Louis

Fri 1/23

6:02 pm-10:00 pm

Nonstop2h 58m

$326

MiamiSt. Louis

MIA - STL

MIASTL

Miami

Mon 2/9

5:10 pm-10:40 pm

1 stop6h 30m

Lambert-St Louis

Tue 2/17

7:50 am-11:30 am

Nonstop2h 40m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 20 results

Best time to book a flight from Key Largo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Key Largo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to St. Louis

How far ahead should I book a flight from Key Largo to St. Louis?

The price you pay for your flight from Key Largo to St. Louis may vary depending on when you book. For the best chance of a lower fare, look to book 62 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Key Largo to St. Louis?

Currently, March is the cheapest month in which you can book a flight from Key Largo to St. Louis (average of $37). Flying from Key Largo to St. Louis in January is currently the most expensive (average of $138). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to STL?

One of the essential ways to save on airfare from Key Largo to St. Louis is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 13% on airfare.

What is the cheapest day to fly from Key Largo to St. Louis?

Travelers seeking maximum savings on their Key Largo to St. Louis flight should consider departing on Tuesday at noon when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to St. Louis

The most flights from KE9 to STL are scheduled on a Thursday (6 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing St. Louis

See what other customers who have flown with Southwest, Delta, and American Airlines from Key Largo to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,250 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,007 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,055 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Spirit Airlines

6.3

Okay

8,189 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Frontier

5.8

Fair

3,081 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airport do you fly into for flights to St. Louis from Key Largo?
If you book a flight to St. Louis from Key Largo, you will be flying to Lambert-St Louis, which is the city’s only airport. Lambert-St Louis (STL) is located 12.7 mi from the center of St. Louis. There are 3 flights from Key Largo to Lambert-St Louis per day from 5 different airlines.
How popular is this Key Largo to St. Louis flight route?
Flights from Key Largo to Lambert-St Louis have been viewed 13 times in the past calendar month.
How long is the flight from Key Largo to St. Louis?
Airlines like American Airlines and Frontier fly from Key Largo to St. Louis in about 3h 08m. The time it takes to get you to your destination can typically vary by up to 2h 02m. The distance from Key Largo to St. Louis is about 1069 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines to fly from Key Largo to St. Louis one-way?
To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $49. Frontier flights start at $69 while deals on Delta start at $98 one-way.
What are the most reliable airlines from Key Largo to St. Louis?
Before booking your flight to St. Louis from Key Largo, check out the most reliable airlines to get you to your destination on time: Envoy Air (86%), Qatar Airways (84%), Royal Air Maroc( 80%).
What are the cheapest flights from Key Largo to St. Louis?
Looking at all options, your cheapest flight can be booked for $89. While the most popular route (Miami - Lambert-St Louis) can be booked for $128 on average, our data indicates $347 when flying from Key Largo to St. Louis.
Can I find deals for flights from Key Largo to St. Louis that include hotel bookings?
Yes. In addition to deals on Key Largo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Key Largo to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to St. Louis.
Can I find deals for business class flights from Key Largo to St. Louis?
Yes. Cheapflights offers flight deals from Key Largo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Key Largo to St. Louis?
Currently, March is the cheapest month in which you can book a flight from Key Largo to St. Louis (average of $37). Flying from Key Largo to St. Louis in January is currently the most expensive (average of $138). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Other flights to St. Louis

Top 5 airlines flying from Key Largo to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$80	Average$183	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$102	Average$244	FlexibilityNo cancel fee	On-time62%
Southwest	Cheapest$186	Average$381	FlexibilityNo cancel fee	On-time63%
Delta	Cheapest$196	Average$336	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$211	Average$421	FlexibilityNo cancel fee	On-time71%

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$59+ Cheap flights from Key Largo, FL to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Key Largo to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Key Largo to Lambert-St Louis are usually found in October or August, booked 62 days in advance, depart on a Thursday or Friday and return on a Sunday

Cheap flight deals from Key Largo to St. Louis

Cheapest flights from Key Largo to St. LouisExplore the most affordable flight options available from Key Largo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Key Largo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Key Largo to St. Louis

Keep the following information in mind while searching for Key Largo to St. Louis flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Key Largo to St. Louis that are best for you.

Best time to book a flight from Key Largo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Key Largo with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to St. Louis

How far ahead should I book a flight from Key Largo to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Key Largo to St. Louis. Price data was last updated on December 12, 2025.

What is the cheapest month to book a flight from Key Largo to St. Louis?

What is the cheapest time of day to fly from KE9 to STL?

Find hourly flight availability from Key Largo to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

What is the cheapest day to fly from Key Largo to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to St. Louis. Price data was last updated on December 16, 2024.

Weekly flight availability from Key Largo to St. Louis

Reviews of airlines servicing St. Louis

See what other customers who have flown with Southwest, Delta, and American Airlines from Key Largo to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Key Largo?

How popular is this Key Largo to St. Louis flight route?

How long is the flight from Key Largo to St. Louis?

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Cheapest flights from Key Largo to St. Louis
Explore the most affordable flight options available from Key Largo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.