$162+ Cheap flights from Harrisburg to St. Louis (MDT - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — STL
Oct 1 — Oct 81
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to St. Louis
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Best
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Cheapest flights from Harrisburg to St. LouisExplore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
Explore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 1, 2026.
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:05 pm -
1 stop4h 24m
Sat 11/214:44 pm -
1 stop5h 22m
Deal found 8/28![Delta logo]()
$301
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:54 pm -
1 stop5h 06m
Sat 9/269:04 am -
1 stop6h 48m
Deal found 8/27![United Airlines logo]()
$310
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:10 pm -
1 stop5h 09m
Mon 10/265:00 am -
1 stop5h 17m
Deal found 8/30![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:45 am -
1 stop5h 44m
Sat 9/195:00 am -
1 stop5h 23m
Deal found 8/28![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am -
1 stop5h 18m
Sun 9/205:45 pm -
1 stop4h 26m
Deal found 8/31![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/291:00 pm -
1 stop5h 26m
Sun 1/36:15 am -
1 stop4h 47m
Deal found 8/31![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:15 am -
1 stop4h 55m
Sun 11/227:30 am -
1 stop4h 54m
Deal found 8/30![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/261:00 pm -
1 stop5h 26m
Thu 12/311:00 pm -
1 stop5h 06m
Deal found 8/31![Delta logo]()
$370
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:54 pm -
1 stop4h 27m
Wed 10/218:00 am -
1 stop4h 27m
Deal found 8/30![United Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:45 am -
1 stop5h 44m
Fri 10/25:00 am -
1 stop5h 23m
Deal found 8/28![American Airlines logo]()
$386
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:30 am -
1 stop6h 43m
Sat 10/246:00 am -
1 stop6h 27m
Deal found 9/1![United Airlines logo]()
$405
Best flights from Harrisburg to St. LouisDiscover carefully curated flight deals from Harrisburg to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
Discover carefully curated flight deals from Harrisburg to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 1, 2026.
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:54 pm -
1 stop6h 04m
Sat 10/249:04 am -
1 stop6h 48m
Deal found 9/1![United Airlines logo]()
$301
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/261:00 pm -
1 stop5h 26m
Thu 12/311:00 pm -
1 stop5h 06m
Deal found 8/27![Delta logo]()
$400
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:54 pm -
1 stop4h 27m
Sat 10/249:04 am -
1 stop6h 48m
Deal found 8/31![United Airlines logo]()
$435
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop4h 25m
Mon 11/306:00 pm -
1 stop4h 06m
Deal found 9/1![Delta logo]()
$479
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/410:35 am -
2 stops12h 18m
Tue 2/98:25 am -
1 stop4h 24m
Deal found 8/30![United Airlines logo]()
$527
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:20 am -
2 stops13h 42m
Thu 12/317:18 am -
1 stop5h 17m
Deal found 8/27![United Airlines logo]()
$651
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:52 pm -
2 stops9h 07m
Wed 9/168:30 am -
1 stop7h 22m
Deal found 8/28![United Airlines logo]()
$696
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/212:40 pm -
2 stops7h 55m
Sun 11/2210:53 am -
1 stop7h 04m
Deal found 8/31![United Airlines logo]()
$736
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:15 am -
2 stops9h 02m
Fri 10/28:00 am -
1 stop4h 27m
Deal found 8/28![United Airlines logo]()
$736
Last-minute flights from Harrisburg to St. LouisDiscover last-minute flight deals from Harrisburg to St. Louis. Data last updated September 1, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to St. Louis. Data last updated September 1, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:52 pm -
1 stop5h 19m
Sun 9/63:32 pm -
1 stop4h 26m
Deal found 8/30![United Airlines logo]()
$408
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:34 pm -
1 stop5h 00m
Mon 9/76:00 am -
1 stop4h 45m
Deal found 8/28![American Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:30 am -
1 stop6h 27m
Sat 9/1912:59 pm -
1 stop6h 59m
Deal found 8/30![United Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/165:45 am -
1 stop5h 44m
Sat 9/195:00 am -
1 stop5h 23m
Deal found 8/28![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am -
1 stop5h 18m
Sun 9/205:45 pm -
1 stop4h 26m
Deal found 8/31![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:54 pm -
1 stop5h 06m
Sat 9/269:04 am -
1 stop6h 48m
Deal found 8/27![United Airlines logo]()
$310
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:45 am -
1 stop5h 44m
Fri 10/25:00 am -
1 stop5h 23m
Deal found 8/28![American Airlines logo]()
$386
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:54 pm -
1 stop4h 27m
Wed 10/218:00 am -
1 stop4h 27m
Deal found 8/30![United Airlines logo]()
$381
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:54 pm -
1 stop6h 04m
Sat 10/249:04 am -
1 stop6h 48m
Deal found 9/1![United Airlines logo]()
$301
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:10 pm -
1 stop5h 09m
Mon 10/265:00 am -
1 stop5h 17m
Deal found 8/30![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:30 am -
1 stop6h 43m
Sat 10/246:00 am -
1 stop6h 27m
Deal found 9/1![United Airlines logo]()
$405
One-way flights from Harrisburg to St. LouisSearch for one-way flight options from Harrisburg to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
Search for one-way flight options from Harrisburg to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:38 pm -
2 stops22h 43m
Deal found 8/31![Multiple Airlines logo]()
$162
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:54 pm -
1 stop5h 06m
Deal found 8/31![United Airlines logo]()
$274
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:54 pm -
1 stop6h 05m
Deal found 8/28![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:34 pm -
1 stop5h 00m
Deal found 8/28![American Airlines logo]()
$413
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:59 pm -
2 stops17h 41m
Deal found 9/1![United Airlines logo]()
$551
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:15 am -
2 stops6h 47m
Deal found 8/28![United Airlines logo]()
$675
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:08 am -
3 stops32h 42m
Deal found 8/28![Multiple Airlines logo]()
$719
Find flight deals from Harrisburg to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $301 (Delta) |
One-way from | $271 (Kiwi.com) |
Popular in | August |
Cheapest in | January |
Average price | $363 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
Use the filters below to find and compare flights from Harrisburg to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sat 10/17
5:54 pm-10:58 pm
1 stop6h 04m
Lambert-St Louis
Sat 10/24
9:04 am-4:52 pm
1 stop6h 48m
$301
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sat 12/26
1:00 pm-5:26 pm
1 stop5h 26m
Lambert-St Louis
Thu 12/31
1:00 pm-7:06 pm
1 stop5h 06m
$400
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Thu 10/22
5:54 pm-9:21 pm
1 stop4h 27m
Lambert-St Louis
Sat 10/24
9:04 am-4:52 pm
1 stop6h 48m
$435
Quickest round-trip
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Thu 11/26
6:00 am-9:25 am
1 stop4h 25m
Lambert-St Louis
Mon 11/30
6:00 pm-11:06 pm
1 stop4h 06m
$479
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Thu 2/4
10:35 am-9:53 pm
2 stops12h 18m
Lambert-St Louis
Tue 2/9
8:25 am-1:49 pm
1 stop4h 24m
$527
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sat 12/26
6:20 am-7:02 pm
2 stops13h 42m
Lambert-St Louis
Thu 12/31
7:18 am-1:35 pm
1 stop5h 17m
$651
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sat 9/12
2:52 pm-10:59 pm
2 stops9h 07m
Lambert-St Louis
Wed 9/16
8:30 am-4:52 pm
1 stop7h 22m
$696
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sat 11/21
2:40 pm-9:35 pm
2 stops7h 55m
Lambert-St Louis
Sun 11/22
10:53 am-6:57 pm
1 stop7h 04m
$736
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Fri 9/25
6:15 am-2:17 pm
2 stops9h 02m
Lambert-St Louis
Fri 10/2
8:00 am-1:27 pm
1 stop4h 27m
$736
Cheapest one-way
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Tue 9/22
5:54 pm-10:00 pm
1 stop5h 06m
$274
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Harrisburg to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Harrisburg with our price prediction graph.
MDT-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to St. Louis
What is the cheapest month to book a flight from Harrisburg to St. Louis?
Currently, January is the cheapest month in which you can book a flight from Harrisburg to St. Louis (average of $304). Flying from Harrisburg to St. Louis in August is currently the most expensive (average of $708). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Harrisburg to St. Louis?
Airfare is below average for this route at the moment.
Harrisburg to St. Louis flights typically cost between $333 and $432 in November.The cheapest round-trip price found within the last 5 days was $301 on Delta (Nov 17-Nov 21).
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 1, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Harrisburg to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Boarding
8.1
Comfort
7.8
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
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Harrisburg and St. Louis flights
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 1, 2026.
Top 3 airlines flying from Harrisburg to St. Louis
Discover the top 3 airlines that operate flights from Harrisburg to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$408 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$379 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$287 | Average$398 | FlexibilityNo cancel fee | On-timeN/A |