$200+ Cheap flights from Harrisburg to St. Louis (MDT - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — STL
May 27 — Jun 31
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
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Cheapest flights from Harrisburg to St. LouisExplore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.
Explore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:20 am
MDT
- STL
1 stop4h 09m
Delta
Tue 6/26:04 pm
STL
- MDT
1 stop3h 46m
Delta
Deal found 4/23![Delta logo]()
$291
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
MDT
- STL
1 stop7h 25m
Delta
Sun 5/315:20 pm
STL
- MDT
1 stop5h 31m
Delta
Deal found 4/23![Delta logo]()
$310
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:04 am
MDT
- STL
1 stop4h 42m
Delta
Mon 6/293:45 pm
STL
- MDT
1 stop7h 10m
Delta
Deal found 4/22![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:54 pm
MDT
- STL
1 stop4h 19m
United Airlines
Sun 5/1011:15 am
STL
- MDT
1 stop6h 30m
United Airlines
Deal found 4/23![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:34 pm
MDT
- STL
1 stop4h 05m
Delta
Mon 7/275:19 pm
STL
- MDT
1 stop5h 34m
Delta
Deal found 4/24![Delta logo]()
$344
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:04 am
MDT
- STL
1 stop4h 42m
Delta
Sun 6/146:30 am
STL
- MDT
1 stop4h 12m
Delta
Deal found 4/23![Delta logo]()
$354
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 pm
MDT
- STL
1 stop5h 09m
Delta
Mon 5/115:20 pm
STL
- MDT
1 stop5h 31m
Delta
Deal found 4/26![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:27 pm
MDT
- STL
1 stop5h 29m
American Airlines
Sun 8/25:48 pm
STL
- MDT
1 stop4h 17m
American Airlines
Deal found 4/25![American Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:41 am
MDT
- STL
1 stop7h 06m
American Airlines
Sun 5/176:29 am
STL
- MDT
1 stop6h 49m
American Airlines
Deal found 4/26![American Airlines logo]()
$389
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:54 pm
MDT
- STL
1 stop4h 19m
United Airlines
Tue 5/1210:25 am
STL
- MDT
1 stop5h 28m
United Airlines
Deal found 4/23![United Airlines logo]()
$419
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:20 am
MDT
- STL
1 stop16h 01m
Multiple Airlines
Sun 5/174:19 pm
STL
- MDT
1 stop15h 11m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$423
Best flights from Harrisburg to St. LouisDiscover carefully curated flight deals from Harrisburg to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 27, 2026.
Discover carefully curated flight deals from Harrisburg to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 27, 2026.
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:20 am
MDT
- STL
1 stop4h 09m
Delta
Tue 6/26:04 pm
STL
- MDT
1 stop3h 46m
Delta
Deal found 4/23![Delta logo]()
$291
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:54 pm
MDT
- STL
1 stop4h 19m
United Airlines
Sun 5/1011:15 am
STL
- MDT
1 stop6h 30m
United Airlines
Deal found 4/23![United Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:20 am
MDT
- STL
1 stop16h 01m
Multiple Airlines
Sun 5/174:19 pm
STL
- MDT
1 stop15h 11m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:04 am
MDT
- STL
1 stop4h 42m
Delta
Sat 6/1310:20 am
STL
- MDT
1 stop5h 34m
Delta
Deal found 4/26![Delta logo]()
$310
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:15 am
MDT
- STL
1 stop4h 17m
Delta
Sun 6/146:00 am
STL
- MDT
1 stop4h 11m
Delta
Deal found 4/25![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:22 pm
MDT
- STL
1 stop6h 34m
Delta
Mon 6/226:00 am
STL
- MDT
1 stop4h 11m
Delta
Deal found 4/26![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3011:56 am
MDT
- STL
1 stop5h 18m
Delta
Sun 8/26:00 am
STL
- MDT
1 stop4h 10m
Delta
Deal found 4/22![Delta logo]()
$329
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:20 am
MDT
- STL
1 stop4h 09m
Delta
Sat 5/1610:19 am
STL
- MDT
1 stop4h 58m
Delta
Deal found 4/27![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:15 am
MDT
- STL
2 stops10h 31m
United Airlines
Wed 6/310:20 am
STL
- MDT
1 stop10h 09m
United Airlines
Deal found 4/26![United Airlines logo]()
$550
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:22 pm
MDT
- STL
1 stop6h 34m
Delta
Fri 6/266:30 am
STL
- MDT
1 stop4h 12m
Delta
Deal found 4/22![Delta logo]()
$424
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:04 am
MDT
- STL
1 stop4h 42m
Delta
Mon 6/156:10 pm
STL
- MDT
1 stop4h 00m
Delta
Deal found 4/23![Delta logo]()
$533
Last-minute flights from Harrisburg to St. LouisDiscover last-minute flight deals from Harrisburg to St. Louis. Data last updated April 27, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to St. Louis. Data last updated April 27, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:54 pm
MDT
- STL
1 stop4h 19m
United Airlines
Sun 5/1011:15 am
STL
- MDT
1 stop6h 30m
United Airlines
Deal found 4/23![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:54 pm
MDT
- STL
1 stop4h 19m
United Airlines
Tue 5/1210:25 am
STL
- MDT
1 stop5h 28m
United Airlines
Deal found 4/23![United Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 pm
MDT
- STL
1 stop5h 09m
Delta
Mon 5/115:20 pm
STL
- MDT
1 stop5h 31m
Delta
Deal found 4/26![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:41 am
MDT
- STL
1 stop7h 06m
American Airlines
Sun 5/176:29 am
STL
- MDT
1 stop6h 49m
American Airlines
Deal found 4/26![American Airlines logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:20 am
MDT
- STL
1 stop16h 01m
Multiple Airlines
Sun 5/174:19 pm
STL
- MDT
1 stop15h 11m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:43 pm
MDT
- STL
1 stop4h 36m
American Airlines
Mon 5/185:21 pm
STL
- MDT
1 stop5h 31m
American Airlines
Deal found 4/23![American Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
MDT
- STL
1 stop7h 25m
Delta
Sun 5/315:20 pm
STL
- MDT
1 stop5h 31m
Delta
Deal found 4/23![Delta logo]()
$310
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:20 am
MDT
- STL
1 stop4h 09m
Delta
Tue 6/26:04 pm
STL
- MDT
1 stop3h 46m
Delta
Deal found 4/23![Delta logo]()
$291
One-way flights from Harrisburg to St. LouisSearch for one-way flight options from Harrisburg to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 27, 2026.
Search for one-way flight options from Harrisburg to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/253:45 pm
MDT
- STL
3 stops42h 10m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:58 pm
MDT
- STL
2 stops39h 59m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$262
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:25 pm
MDT
- STL
1 stop4h 33m
Delta
Deal found 4/26![Delta logo]()
$267
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:33 pm
MDT
- STL
1 stop6h 26m
Delta
Deal found 4/22![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:50 pm
MDT
- STL
1 stop5h 41m
American Airlines
Deal found 4/22![American Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:40 am
MDT
- STL
1 stop6h 55m
American Airlines
Deal found 4/26![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:40 pm
MDT
- STL
1 stop5h 31m
Delta
Deal found 4/24![Delta logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/34:26 pm
MDT
- STL
3 stops27h 10m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:00 am
MDT
- STL
1 stop5h 34m
Delta
Deal found 4/22![Delta logo]()
$408
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:15 am
MDT
- STL
2 stops9h 03m
United Airlines
Deal found 4/26![United Airlines logo]()
$422
Find flight deals from Harrisburg to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $291 (Delta) |
One-way from | $200 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $381 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
Use the filters below to find and compare flights from Harrisburg to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Fri 5/29
6:20 am-9:29 am
1 stop4h 09m
Lambert-St Louis
Tue 6/2
6:04 pm-10:50 pm
1 stop3h 46m
$291
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Thu 6/11
6:04 am-9:46 am
1 stop4h 42m
Lambert-St Louis
Sat 6/13
10:20 am-4:54 pm
1 stop5h 34m
$310
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Thu 6/11
6:15 am-9:32 am
1 stop4h 17m
Lambert-St Louis
Sun 6/14
6:00 am-11:11 am
1 stop4h 11m
$329
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Fri 6/19
6:22 pm-11:56 pm
1 stop6h 34m
Lambert-St Louis
Mon 6/22
6:00 am-11:11 am
1 stop4h 11m
$329
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Thu 7/30
11:56 am-4:14 pm
1 stop5h 18m
Lambert-St Louis
Sun 8/2
6:00 am-11:10 am
1 stop4h 10m
$329
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Fri 5/8
5:54 pm-9:13 pm
1 stop4h 19m
Lambert-St Louis
Sun 5/10
11:15 am-6:45 pm
1 stop6h 30m
$339
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Tue 5/12
6:20 am-9:29 am
1 stop4h 09m
Lambert-St Louis
Sat 5/16
10:19 am-4:17 pm
1 stop4h 58m
$339
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Fri 5/15
9:20 am-12:21 am
1 stop16h 01m
Lambert-St Louis
Sun 5/17
4:19 pm-8:30 am
1 stop15h 11m
$423
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Fri 6/19
6:22 pm-11:56 pm
1 stop6h 34m
Lambert-St Louis
Fri 6/26
6:30 am-11:42 am
1 stop4h 12m
$424
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Mon 6/15
6:04 am-9:46 am
1 stop4h 42m
Lambert-St Louis
Mon 6/15
6:10 pm-11:10 pm
1 stop4h 00m
$533
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Harrisburg to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to St. Louis in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Harrisburg with our price prediction graph.
MDT-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to St. Louis
What is the cheapest month to book a flight from Harrisburg to St. Louis?
Currently, January is the cheapest month in which you can book a flight from Harrisburg to St. Louis (average of $304). Flying from Harrisburg to St. Louis in March is currently the most expensive (average of $469). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Harrisburg to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated April 27, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Harrisburg to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.9
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.9
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.9
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.9
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Alternative routes for Harrisburg to St. Louis
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Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
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Harrisburg and St. Louis flights
Browse other Harrisburg and St. Louis flight options. Last updated on April 27, 2026.
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 27, 2026.
Top 3 airlines flying from Harrisburg to St. Louis
Discover the top 3 airlines that operate flights from Harrisburg to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$432 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$355 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$378 | FlexibilityNo cancel fee | On-timeN/A |