$117+ Cheap flights from Harrisburg to St. Louis (MDT - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — STL
Apr 29 — Mai 61
Round-trip
1 adult, Economy
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Best
Last-minute
One-way
Cheapest flights from Harrisburg to St. LouisExplore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on März 30, 2026.
Explore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on März 30, 2026.
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 3/2610:13 pm
MDT
- STL
1 stop9h 49m
Frontier
So 3/297:52 am
STL
- MDT
1 stop12h 36m
Frontier
Deal found 3/25![Frontier logo]()
$250
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 5/165:54 pm
MDT
- STL
1 stop5h 51m
United Airlines
Mo 5/187:09 pm
STL
- MDT
1 stop4h 46m
United Airlines
Deal found 3/26![United Airlines logo]()
$310
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/236:43 pm
MDT
- STL
1 stop6h 03m
American Airlines
Sa 4/258:57 am
STL
- MDT
1 stop6h 09m
American Airlines
Deal found 3/30![American Airlines logo]()
$329
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/99:11 pm
MDT
- STL
1 stop11h 40m
Frontier
Mo 4/138:41 am
STL
- MDT
1 stop12h 32m
Frontier
Deal found 3/25![Frontier logo]()
$330
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/235:52 pm
MDT
- STL
1 stop4h 21m
United Airlines
So 4/269:10 am
STL
- MDT
1 stop6h 41m
United Airlines
Deal found 3/30![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 11/66:48 am
MDT
- STL
1 stop8h 32m
American Airlines
So 11/86:00 am
STL
- MDT
1 stop3h 43m
American Airlines
Deal found 3/28![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 7/106:22 pm
MDT
- STL
1 stop6h 31m
Delta
Di 7/146:30 am
STL
- MDT
1 stop4h 11m
Delta
Deal found 3/29![Delta logo]()
$355
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/134:36 pm
MDT
- STL
1 stop6h 43m
American Airlines
So 5/176:29 am
STL
- MDT
1 stop6h 49m
American Airlines
Deal found 3/27![American Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 3/316:32 pm
MDT
- STL
1 stop6h 26m
Delta
Sa 4/45:57 pm
STL
- MDT
1 stop3h 52m
Delta
Deal found 3/26![Delta logo]()
$363
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 7/3011:56 am
MDT
- STL
1 stop5h 18m
Delta
So 8/26:00 am
STL
- MDT
1 stop4h 10m
Delta
Deal found 3/27![Delta logo]()
$374
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 3/306:32 pm
MDT
- STL
1 stop6h 26m
Delta
Sa 4/45:57 pm
STL
- MDT
1 stop3h 52m
Delta
Deal found 3/26![Delta logo]()
$379
Best flights from Harrisburg to St. LouisDiscover carefully curated flight deals from Harrisburg to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated März 30, 2026.
Discover carefully curated flight deals from Harrisburg to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated März 30, 2026.
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 5/165:54 pm
MDT
- STL
1 stop5h 51m
United Airlines
Mo 5/187:09 pm
STL
- MDT
1 stop4h 46m
United Airlines
Deal found 3/26![United Airlines logo]()
$310
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/99:11 pm
MDT
- STL
1 stop11h 40m
Frontier
Mo 4/138:41 am
STL
- MDT
1 stop12h 32m
Frontier
Deal found 3/25![Frontier logo]()
$330
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 7/106:22 pm
MDT
- STL
1 stop6h 31m
Delta
Di 7/146:30 am
STL
- MDT
1 stop4h 11m
Delta
Deal found 3/29![Delta logo]()
$355
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 7/2311:56 am
MDT
- STL
1 stop5h 18m
Delta
Mo 7/273:40 pm
STL
- MDT
1 stop7h 13m
Delta
Deal found 3/28![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 7/106:15 am
MDT
- STL
1 stop5h 12m
United Airlines
Mo 7/135:33 pm
STL
- MDT
1 stop6h 12m
United Airlines
Deal found 3/26![United Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 7/3011:56 am
MDT
- STL
1 stop5h 18m
Delta
So 8/26:30 am
STL
- MDT
1 stop4h 11m
Delta
Deal found 3/28![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 4/245:53 pm
MDT
- STL
1 stop4h 59m
United Airlines
Fr 5/17:09 pm
STL
- MDT
1 stop4h 46m
United Airlines
Deal found 3/27![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 7/166:04 am
MDT
- STL
1 stop4h 39m
Delta
Do 7/236:30 am
STL
- MDT
1 stop4h 11m
Delta
Deal found 3/28![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sa 9/2610:35 am
MDT
- STL
1 stop6h 03m
United Airlines
Di 9/298:25 am
STL
- MDT
1 stop4h 24m
United Airlines
Deal found 3/25![United Airlines logo]()
$415
Last-minute flights from Harrisburg to St. LouisDiscover last-minute flight deals from Harrisburg to St. Louis. Data last updated März 30, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to St. Louis. Data last updated März 30, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mo 3/306:32 pm
MDT
- STL
1 stop6h 26m
Delta
Sa 4/45:57 pm
STL
- MDT
1 stop3h 52m
Delta
Deal found 3/26![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Di 3/316:32 pm
MDT
- STL
1 stop6h 26m
Delta
Sa 4/45:57 pm
STL
- MDT
1 stop3h 52m
Delta
Deal found 3/26![Delta logo]()
$363
This Frontier deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/210:06 pm
MDT
- STL
1 stop10h 22m
Frontier
Sa 4/48:41 am
STL
- MDT
1 stop11h 40m
Frontier
Deal found 3/27![Frontier logo]()
$400
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/99:11 pm
MDT
- STL
1 stop11h 40m
Frontier
Mo 4/138:41 am
STL
- MDT
1 stop12h 32m
Frontier
Deal found 3/25![Frontier logo]()
$330
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/236:43 pm
MDT
- STL
1 stop6h 03m
American Airlines
Sa 4/258:57 am
STL
- MDT
1 stop6h 09m
American Airlines
Deal found 3/30![American Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/235:52 pm
MDT
- STL
1 stop4h 21m
United Airlines
So 4/269:10 am
STL
- MDT
1 stop6h 41m
United Airlines
Deal found 3/30![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 4/235:52 pm
MDT
- STL
1 stop4h 21m
United Airlines
Fr 5/17:09 pm
STL
- MDT
1 stop4h 46m
United Airlines
Deal found 3/27![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 4/265:52 pm
MDT
- STL
1 stop5h 00m
United Airlines
So 5/37:09 pm
STL
- MDT
1 stop4h 46m
United Airlines
Deal found 3/26![United Airlines logo]()
$508
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 4/292:50 pm
MDT
- STL
1 stop5h 39m
American Airlines
Mo 5/45:51 am
STL
- MDT
1 stop4h 32m
American Airlines
Deal found 3/25![American Airlines logo]()
$310
One-way flights from Harrisburg to St. LouisSearch for one-way flight options from Harrisburg to St. Louis. Find affordable one-way fares based on user searches. Data last updated März 30, 2026.
Search for one-way flight options from Harrisburg to St. Louis. Find affordable one-way fares based on user searches. Data last updated März 30, 2026.
This Frontier deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 4/1210:06 pm
MDT
- STL
1 stop10h 45m
Frontier
Deal found 3/30![Frontier logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 6/45:58 pm
MDT
- STL
2 stops39h 57m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 5/35:43 pm
MDT
- STL
3 stops48h 53m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fr 7/311:37 am
MDT
- STL
2 stops7h 59m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$199
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mi 5/136:00 am
MDT
- STL
1 stop4h 44m
Delta
Deal found 3/29![Delta logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 4/1210:06 pm
MDT
- STL
3 stops45h 30m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 5/146:01 pm
MDT
- STL
2 stops39h 54m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
So 5/36:40 am
MDT
- STL
1 stop7h 08m
American Airlines
Deal found 3/29![American Airlines logo]()
$267
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Do 7/212:02 pm
MDT
- STL
1 stop6h 20m
American Airlines
Deal found 3/27![American Airlines logo]()
$279
Find flight deals from Harrisburg to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated März 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $310 (United Airlines) |
One-way from | $117 (Frontier) |
Popular in | March |
Cheapest in | May |
Average price | $466 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated März 30, 2026.
Use the filters below to find and compare flights from Harrisburg to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Sa 5/16
5:54 pm-10:45 pm
1 stop5h 51m
Lambert-St Louis
Mo 5/18
7:09 pm-12:55 am
1 stop4h 46m
$310
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Do 4/9
9:11 pm-7:51 am
1 stop11h 40m
Lambert-St Louis
Mo 4/13
8:41 am-10:13 pm
1 stop12h 32m
$330
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Fr 7/10
6:22 pm-11:53 pm
1 stop6h 31m
Lambert-St Louis
Di 7/14
6:30 am-11:41 am
1 stop4h 11m
$355
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Do 7/23
11:56 am-4:14 pm
1 stop5h 18m
Lambert-St Louis
Mo 7/27
3:40 pm-11:53 pm
1 stop7h 13m
$374
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Do 7/30
11:56 am-4:14 pm
1 stop5h 18m
Lambert-St Louis
So 8/2
6:30 am-11:41 am
1 stop4h 11m
$374
Quickest round-trip
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Do 7/16
6:04 am-9:43 am
1 stop4h 39m
Lambert-St Louis
Do 7/23
6:30 am-11:41 am
1 stop4h 11m
$374
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Fr 7/10
6:15 am-10:27 am
1 stop5h 12m
Lambert-St Louis
Mo 7/13
5:33 pm-12:45 am
1 stop6h 12m
$397
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Fr 4/24
5:53 pm-9:52 pm
1 stop4h 59m
Lambert-St Louis
Fr 5/1
7:09 pm-12:55 am
1 stop4h 46m
$409
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Sa 9/26
10:35 am-3:38 pm
1 stop6h 03m
Lambert-St Louis
Di 9/29
8:25 am-1:49 pm
1 stop4h 24m
$415
Cheapest one-way
HarrisburgSt. Louis
MDT - STL
MDTSTL
Harrisburg
Fr 7/3
11:37 am-6:36 pm
2 stops7h 59m
$199
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Harrisburg to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to St. Louis in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Harrisburg with our price prediction graph.
MDT-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to St. Louis
What is the cheapest month to book a flight from Harrisburg to St. Louis?
Currently, September is the cheapest month in which you can book a flight from Harrisburg to St. Louis (average of $109). Flying from Harrisburg to St. Louis in January is currently the most expensive (average of $272). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Harrisburg to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated März 30, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Harrisburg to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Top 3 airlines flying from Harrisburg to St. Louis
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$432 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$327 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$323 | FlexibilityNo cancel fee | On-timeN/A |