$172+ Cheap flights from Harrisburg to St. Louis (MDT - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/13. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — STL
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to St. Louis
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Best
Last-minute
One-way
Cheapest flights from Harrisburg to St. LouisExplore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:54 pm -
1 stop4h 27m
Sat 10/318:00 am -
1 stop4h 58m
Deal found 9/2![United Airlines logo]()
$301
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:45 am -
1 stop5h 44m
Sat 10/105:40 pm -
1 stop4h 19m
Deal found 9/5![American Airlines logo]()
$310
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:34 am -
1 stop5h 13m
Mon 11/167:26 am -
1 stop6h 19m
Deal found 9/4![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:13 am -
1 stop4h 36m
Sat 11/214:44 pm -
1 stop5h 22m
Deal found 9/5![Delta logo]()
$330
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:15 pm -
1 stop3h 59m
Sun 10/46:40 am -
1 stop3h 55m
Deal found 9/6![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:15 pm -
1 stop3h 59m
Sun 9/206:40 am -
1 stop3h 55m
Deal found 9/1![Delta logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:59 pm -
2 stops16h 22m
Thu 11/54:26 pm -
1 stop20h 40m
Deal found 9/2![Multiple Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:03 am -
1 stop5h 31m
Mon 11/3011:14 am -
1 stop7h 11m
Deal found 9/5![American Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:54 pm -
1 stop6h 33m
Sun 9/206:30 am -
1 stop6h 40m
Deal found 9/1![American Airlines logo]()
$404
Best flights from Harrisburg to St. LouisDiscover carefully curated flight deals from Harrisburg to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Harrisburg to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:15 pm -
1 stop3h 59m
Sat 10/106:47 am -
1 stop3h 46m
Deal found 9/2![Delta logo]()
$301
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/48:16 pm -
1 stop4h 43m
Tue 2/95:00 am -
1 stop7h 29m
Deal found 9/3![American Airlines logo]()
$310
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:52 pm -
1 stop5h 19m
Wed 9/2312:59 pm -
1 stop6h 59m
Deal found 9/4![United Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:08 am -
1 stop5h 42m
Sun 10/255:00 am -
1 stop5h 17m
Deal found 9/5![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:13 am -
1 stop4h 36m
Sat 11/214:44 pm -
1 stop5h 22m
Deal found 9/5![Delta logo]()
$330
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/268:14 pm -
1 stop4h 45m
Thu 12/319:20 am -
1 stop4h 47m
Deal found 9/1![American Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2212:09 pm -
1 stop6h 05m
Sat 11/286:00 pm -
1 stop4h 06m
Deal found 9/2![Delta logo]()
$449
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/410:35 am -
2 stops12h 18m
Tue 2/98:25 am -
1 stop4h 24m
Deal found 9/4![United Airlines logo]()
$527
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:15 pm -
1 stop6h 49m
Sat 11/287:26 am -
1 stop6h 18m
Deal found 9/4![American Airlines logo]()
$464
Last-minute flights from Harrisburg to St. LouisDiscover last-minute flight deals from Harrisburg to St. Louis. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to St. Louis. Data last updated September 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:34 pm -
1 stop5h 00m
Mon 9/76:00 am -
1 stop4h 45m
Deal found 9/2![American Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:14 pm -
1 stop7h 20m
Tue 9/86:00 am -
1 stop5h 45m
Deal found 9/2![American Airlines logo]()
$423
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:38 pm -
2 stops22h 53m
Thu 9/175:19 pm -
1 stop13h 59m
Deal found 9/2![Multiple Airlines logo]()
$462
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:30 am -
1 stop6h 27m
Mon 9/218:30 am -
1 stop7h 22m
Deal found 9/2![United Airlines logo]()
$494
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:54 pm -
1 stop6h 33m
Sun 9/206:30 am -
1 stop6h 40m
Deal found 9/1![American Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:54 pm -
1 stop6h 05m
Tue 9/2212:59 pm -
1 stop6h 59m
Deal found 9/3![United Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:15 pm -
1 stop3h 59m
Sun 9/206:40 am -
1 stop3h 55m
Deal found 9/1![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
1 stop5h 18m
Sat 9/2611:01 am -
1 stop6h 12m
Deal found 9/3![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:00 am -
1 stop5h 18m
Tue 9/2911:01 am -
1 stop6h 12m
Deal found 9/3![American Airlines logo]()
$547
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:45 am -
1 stop5h 44m
Sat 10/105:40 pm -
1 stop4h 19m
Deal found 9/5![American Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:15 pm -
1 stop3h 59m
Sun 10/46:40 am -
1 stop3h 55m
Deal found 9/6![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2412:13 pm -
1 stop4h 24m
Sat 10/3110:35 am -
1 stop4h 31m
Deal found 9/1![Delta logo]()
$301
One-way flights from Harrisburg to St. LouisSearch for one-way flight options from Harrisburg to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Harrisburg to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:38 pm -
2 stops22h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$172
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:09 pm -
1 stop5h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:53 am -
3 stops36h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:03 am -
3 stops27h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:54 pm -
1 stop4h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![United Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:13 am -
3 stops34h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$412
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/135:45 am -
1 stop5h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$413
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:15 am -
1 stop4h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![United Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:15 am -
2 stops9h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![United Airlines logo]()
$493
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:54 pm -
1 stop6h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![United Airlines logo]()
$509
Find flight deals from Harrisburg to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $301 (United Airlines) |
One-way from | $172 (Kiwi.com) |
Popular in | August |
Cheapest in | January |
Average price | $363 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Harrisburg to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sat 10/10
8:09 pm-12:19 am
1 stop5h 10m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$274
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Fri 10/23
10:42 am-5:00 pm
1 stop7h 18m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$274
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sat 10/3
12:15 pm-3:14 pm
1 stop3h 59m
Lambert-St Louis
Sat 10/10
6:47 am-11:33 am
1 stop3h 46m
$301
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sat 10/10
11:53 am-11:13 pm
3 stops36h 20m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$308
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Thu 2/4
8:16 pm-11:59 pm
1 stop4h 43m
Lambert-St Louis
Tue 2/9
5:00 am-1:29 pm
1 stop7h 29m
$310
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Fri 10/23
6:08 am-10:50 am
1 stop5h 42m
Lambert-St Louis
Sun 10/25
5:00 am-11:17 am
1 stop5h 17m
$319
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Mon 9/21
11:03 am-1:31 pm
3 stops27h 28m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$330
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sun 11/8
6:13 am-9:49 am
1 stop4h 36m
Lambert-St Louis
Sat 11/21
4:44 pm-11:06 pm
1 stop5h 22m
$330
Quickest round-trip
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Fri 9/18
5:54 pm-9:36 pm
1 stop4h 42m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$369
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Fri 10/23
9:13 am-6:57 pm
3 stops34h 44m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$412
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Harrisburg to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to St. Louis in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Harrisburg with our price prediction graph.
MDT-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to St. Louis
What is the cheapest month to book a flight from Harrisburg to St. Louis?
Currently, January is the cheapest month in which you can book a flight from Harrisburg to St. Louis (average of $304). Flying from Harrisburg to St. Louis in August is currently the most expensive (average of $708). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Harrisburg to St. Louis?
Airfare is below average for this route at the moment.
Harrisburg to St. Louis flights typically cost between $333 and $432 in October.The cheapest round-trip price found within the last 5 days was $301 on United Airlines (Oct 24-Oct 31).
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 7, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Harrisburg to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Comfort
7.8
Overall
7.8
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
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Top 3 airlines flying from Harrisburg to St. Louis
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$408 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$379 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$287 | Average$398 | FlexibilityNo cancel fee | On-timeN/A |