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St. Louis

$310+ Cheap flights from Harrisburg to St. Louis (MDT - STL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — STL
Aug 31 — Sep 71
Mon 8/31
Mon 9/7
1 adult, Economy
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Find cheap flights from Harrisburg to St. Louis with Cheapflights

1. Tell us where you want to go

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Cheap flight deals from Harrisburg to St. Louis

Cheapest flights from Harrisburg to St. Louis
Explore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2026.

This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:45 am
MDT
-
STL
1 stop5h 44m
American Airlines
Sat 10/35:00 am
STL
-
MDT
1 stop5h 23m
American Airlines
Deal found 7/30$310
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:31 pm
MDT
-
STL
1 stop5h 43m
American Airlines
Sun 8/305:00 am
STL
-
MDT
1 stop6h 45m
American Airlines
Deal found 7/27$319
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:54 pm
MDT
-
STL
1 stop5h 06m
United Airlines
Thu 8/2012:59 pm
STL
-
MDT
1 stop6h 54m
United Airlines
Deal found 7/28$334
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:31 pm
MDT
-
STL
1 stop5h 27m
American Airlines
Sun 9/65:00 am
STL
-
MDT
1 stop6h 45m
American Airlines
Deal found 7/31$340
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:22 pm
MDT
-
STL
1 stop4h 53m
Delta
Wed 9/23:39 pm
STL
-
MDT
1 stop7h 04m
Delta
Deal found 7/27$354
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:22 pm
MDT
-
STL
1 stop6h 16m
Delta
Sat 8/156:30 am
STL
-
MDT
1 stop4h 06m
Delta
Deal found 7/31$378
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:15 pm
MDT
-
STL
1 stop4h 27m
Delta
Mon 8/106:25 pm
STL
-
MDT
1 stop3h 56m
Delta
Deal found 7/27$379
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:17 pm
MDT
-
STL
1 stop6h 43m
United Airlines
Tue 9/1512:59 pm
STL
-
MDT
1 stop7h 02m
United Airlines
Deal found 7/29$381
This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:34 pm
MDT
-
STL
1 stop5h 00m
American Airlines
Mon 9/76:00 am
STL
-
MDT
1 stop4h 45m
American Airlines
Deal found 8/1$384
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:54 pm
MDT
-
STL
1 stop4h 42m
United Airlines
Sun 9/138:30 am
STL
-
MDT
1 stop7h 22m
United Airlines
Deal found 7/31$390

Find flight deals from Harrisburg to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$310
(American Airlines)

Popular in

March

Cheapest in

January

Average price

$323
Provider with most accurate pricing for Harrisburg-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Lambert-St Louis flights.
Search Deals
From Harrisburg to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
Use the filters below to find and compare flights from Harrisburg to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Wed 9/16

6:10 am-9:29 am

1 stop4h 19m

Lambert-St Louis

Sun 9/20

6:40 am-11:35 am

1 stop3h 55m

$310

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Fri 9/4

5:54 pm-10:00 pm

1 stop5h 06m

Lambert-St Louis

Mon 9/7

8:30 am-4:52 pm

1 stop7h 22m

$319

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Thu 9/3

6:00 am-9:20 am

1 stop4h 20m

Lambert-St Louis

Mon 9/7

5:23 pm-11:43 pm

1 stop5h 20m

$319

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Wed 8/19

10:40 am-3:38 pm

1 stop5h 58m

Lambert-St Louis

Thu 8/27

6:00 am-1:32 pm

1 stop6h 32m

$334

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Wed 8/5

12:22 pm-5:38 pm

1 stop6h 16m

Lambert-St Louis

Sat 8/15

6:00 am-11:49 am

1 stop4h 49m

$378

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Thu 9/10

6:30 am-11:57 am

1 stop6h 27m

Lambert-St Louis

Sun 9/13

8:30 am-4:52 pm

1 stop7h 22m

$400

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Sat 9/12

10:30 am-8:00 pm

2 stops10h 30m

Lambert-St Louis

Tue 9/15

12:59 pm-9:01 pm

1 stop7h 02m

$463

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Wed 8/12

5:54 pm-10:00 pm

1 stop5h 06m

Lambert-St Louis

Sun 8/16

8:50 am-4:52 pm

1 stop7h 02m

$494

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Fri 8/28

6:15 am-3:38 pm

2 stops10h 23m

Lambert-St Louis

Sun 8/30

9:30 am-4:52 pm

1 stop6h 22m

$538
Cheapest one-way
Quickest one-way

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Fri 8/14

7:34 pm-11:34 pm

1 stop5h 00m

$369

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Compare providers for flights from Harrisburg to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to St. Louis in August.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to St. Louis

What is the cheapest month to book a flight from Harrisburg to St. Louis?

Currently, January is the cheapest month in which you can book a flight from Harrisburg to St. Louis (average of $304). Flying from Harrisburg to St. Louis in March is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Harrisburg to St. Louis?

Airfare is typical for this route at the moment.

Harrisburg to St. Louis flights typically cost between $290 and $348 in October.
The cheapest round-trip price found within the last 5 days was $310 on American Airlines (Oct 2-Oct 3).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated August 1, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Harrisburg to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,497 reviews

Food

7.2

Overall

7.8

Crew

8.5

Entertainment

7.8

Comfort

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,497 reviews
Delta
7.8
Good
8,497 reviews

Food

7.2

Overall

7.8

Crew

8.5

Entertainment

7.8

Comfort

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
10,062 reviews
Delta
7.8
Good
8,497 reviews

Food

7.2

Overall

7.8

Crew

8.5

Entertainment

7.8

Comfort

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,845 reviews
Delta
7.8
Good
8,497 reviews

Food

7.2

Overall

7.8

Crew

8.5

Entertainment

7.8

Comfort

7.8

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to St. Louis?

    Departing from Harrisburg to St. Louis will take you 4h 19m. Harrisburg and St. Louis are separated by a distance of 731 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Harrisburg to St. Louis round-trip?

    American Airlines, at $248, was found to be the cheapest airline from Harrisburg to St. Louis.Alternate airlines to your destination round-trip include United Airlines and Delta. American Airlines is currently priced 37% below the average price you’ll pay for this route.

  • Can I find deals for flights from Harrisburg to St. Louis that include hotel bookings?

    Yes. In addition to deals on Harrisburg to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to St. Louis.

  • Can I find deals for business class flights from Harrisburg to St. Louis?

    Yes. Cheapflights offers flight deals from Harrisburg to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to St. Louis?

    Currently, January is the cheapest month in which you can book a flight from Harrisburg to St. Louis (average of $304). Flying from Harrisburg to St. Louis in March is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Farmington

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Harrisburg to St. Louis

Discover the top 3 airlines that operate flights from Harrisburg to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$428FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$379FlexibilityNo cancel feeOn-time71%
DeltaCheapest$251Average$363FlexibilityNo cancel feeOn-timeN/A

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