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St. Louis

$184+ Cheap flights from Harrisburg to St. Louis (MDT - STL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — STL
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Harrisburg to St. Louis

Cheapest flights from Harrisburg to St. Louis
Explore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Frontier deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1011:27 am
MDT
-
STL
1 stop12h 00m
Frontier
Sat 2/149:41 am
STL
-
MDT
1 stop7h 45m
Frontier
Deal found 1/26$184
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:35 pm
MDT
-
STL
1 stop4h 29m
American Airlines
Wed 3/47:05 am
STL
-
MDT
1 stop7h 30m
American Airlines
Deal found 1/27$260
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/135:55 pm
MDT
-
STL
1 stop6h 41m
Delta
Mon 2/236:00 am
STL
-
MDT
1 stop4h 10m
Delta
Deal found 1/27$269
This Expedia deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/318:25 pm
MDT
-
STL
1 stop12h 59m
Frontier
Sun 2/88:59 am
STL
-
MDT
1 stop8h 56m
Frontier
Deal found 1/27$276
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:51 pm
MDT
-
STL
1 stop5h 10m
American Airlines
Sat 3/281:30 pm
STL
-
MDT
1 stop4h 55m
American Airlines
Deal found 1/26$281
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1210:13 pm
MDT
-
STL
1 stop10h 09m
Frontier
Mon 3/168:10 pm
STL
-
MDT
1 stop20h 42m
Frontier
Deal found 1/27$284
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1011:27 am
MDT
-
STL
1 stop12h 00m
Multiple Airlines
Fri 2/138:20 pm
STL
-
MDT
2 stops21h 06m
Multiple Airlines
Deal found 1/27$290
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/611:27 am
MDT
-
STL
2 stops20h 24m
Multiple Airlines
Mon 2/95:42 pm
STL
-
MDT
1 stop15h 50m
Multiple Airlines
Deal found 1/27$310
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2010:46 am
MDT
-
STL
1 stop14h 41m
Frontier
Sun 3/110:11 pm
STL
-
MDT
2 stops35h 21m
Frontier
Deal found 1/26$329
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/76:30 am
MDT
-
STL
1 stop5h 32m
United Airlines
Wed 2/118:05 am
STL
-
MDT
1 stop7h 29m
United Airlines
Deal found 1/27$339

Find flight deals from Harrisburg to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$184
(Frontier)

Popular in

December

Cheapest in

February

Average price

$328
Provider with most accurate pricing for Harrisburg-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Lambert-St Louis flights.
Search Deals
From Harrisburg to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($51 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Harrisburg to St. Louis that are best for you.

Fly from

Harrisburg

Fly to

St. Louis

Route

Depart

Return

Price

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Tue 2/10

11:27 am-10:27 pm

1 stop12h 00m

Lambert-St Louis

Sat 2/14

9:41 am-6:26 pm

1 stop7h 45m

$184

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Fri 2/27

6:31 pm-11:35 pm

1 stop6h 04m

Lambert-St Louis

Wed 3/4

6:00 am-12:01 pm

1 stop5h 01m

$260

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Fri 2/13

5:55 pm-11:36 pm

1 stop6h 41m

Lambert-St Louis

Mon 2/23

6:00 am-11:10 am

1 stop4h 10m

$269

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Fri 2/20

6:31 pm-11:35 pm

1 stop6h 04m

Lambert-St Louis

Sun 3/1

6:00 am-12:19 pm

1 stop5h 19m

$269

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Fri 2/13

7:35 pm-10:52 pm

1 stop4h 17m

Lambert-St Louis

Mon 2/23

2:19 pm-10:18 pm

1 stop6h 59m

$269

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Fri 2/13

7:35 pm-10:52 pm

1 stop4h 17m

Lambert-St Louis

Mon 2/16

9:37 am-5:50 pm

1 stop7h 13m

$269

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Tue 3/24

12:51 pm-5:01 pm

1 stop5h 10m

Lambert-St Louis

Sat 3/28

1:30 pm-7:25 pm

1 stop4h 55m

$281

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Thu 3/12

10:13 pm-7:22 am

1 stop10h 09m

Lambert-St Louis

Mon 3/16

8:10 pm-5:52 pm

1 stop20h 42m

$284

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Tue 2/10

11:27 am-10:27 pm

1 stop12h 00m

Lambert-St Louis

Fri 2/13

8:20 pm-6:26 pm

2 stops21h 06m

$290

HarrisburgSt. Louis

MDT - STL

MDTSTL

Harrisburg

Fri 2/20

10:46 am-12:27 am

1 stop14h 41m

Lambert-St Louis

Sun 3/1

10:11 pm-10:32 am

2 stops35h 21m

$329

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 13 results
1
2

Compare providers for flights from Harrisburg to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to St. Louis in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Harrisburg-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Harrisburg-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Harrisburg to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to St. Louis

What is the cheapest month to book a flight from Harrisburg to St. Louis?

Currently, September is the cheapest month in which you can book a flight from Harrisburg to St. Louis (average of $109). Flying from Harrisburg to St. Louis in June is currently the most expensive (average of $263). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Harrisburg to St. Louis?

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated January 28, 2026.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Harrisburg to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,124 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,124 reviews
Delta
7.9
Good
8,124 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,212 reviews
Delta
7.9
Good
8,124 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,201 reviews
Delta
7.9
Good
8,124 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Harrisburg to St. Louis?

    Departing from Harrisburg to St. Louis will take you 6h 04m. Harrisburg and St. Louis are separated by a distance of 731 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Harrisburg to St. Louis round-trip?

    American Airlines, at $248, was found to be the cheapest airline from Harrisburg to St. Louis.Alternate airlines to your destination round-trip include United Airlines and Delta. American Airlines is currently priced 27% below the average price you’ll pay for this route.

  • Can I find deals for flights from Harrisburg to St. Louis that include hotel bookings?

    Yes. In addition to deals on Harrisburg to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to St. Louis.

  • Can I find deals for business class flights from Harrisburg to St. Louis?

    Yes. Cheapflights offers flight deals from Harrisburg to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to St. Louis?

    Currently, September is the cheapest month in which you can book a flight from Harrisburg to St. Louis (average of $109). Flying from Harrisburg to St. Louis in June is currently the most expensive (average of $263). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Harrisburg to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Harrisburg to St. Louis

Discover the top 3 airlines that operate flights from Harrisburg to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$353FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$326FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$323FlexibilityNo cancel feeOn-timeN/A

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