$160+ Cheap flights from Harrisburg to St. Louis (MDT - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — STL
Nov 19 — Nov 261
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to St. Louis
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Cheapest flights from Harrisburg to St. LouisExplore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
Explore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:27 pm -
1 stop7h 50m
Sat 12/56:02 am -
1 stop4h 25m
Deal found 10/15![American Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:30 am -
1 stop5h 02m
Fri 11/2710:53 am -
1 stop7h 04m
Deal found 10/18![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:15 pm -
1 stop6h 07m
Mon 11/231:14 pm -
1 stop5h 11m
Deal found 10/15![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:15 am -
1 stop4h 55m
Mon 11/161:08 pm -
1 stop4h 49m
Deal found 10/16![United Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:15 am -
1 stop4h 55m
Thu 11/195:00 am -
1 stop7h 24m
Deal found 10/15![United Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:15 am -
1 stop4h 55m
Tue 11/101:08 pm -
1 stop7h 25m
Deal found 10/15![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:09 pm -
1 stop5h 10m
Sun 11/16:02 am -
1 stop6h 27m
Deal found 10/16![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:55 pm -
1 stop5h 06m
Sat 11/286:02 am -
1 stop6h 30m
Deal found 10/18![American Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop4h 25m
Sun 11/226:40 am -
1 stop3h 49m
Deal found 10/19![Delta logo]()
$389
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:03 am -
1 stop7h 11m
Mon 11/3011:14 am -
1 stop7h 11m
Deal found 10/17![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:09 pm -
1 stop5h 10m
Wed 10/216:00 am -
1 stop4h 42m
Deal found 10/17![American Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:08 am -
1 stop5h 42m
Sun 10/256:00 am -
1 stop4h 42m
Deal found 10/15![American Airlines logo]()
$429
Best flights from Harrisburg to St. LouisDiscover carefully curated flight deals from Harrisburg to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
Discover carefully curated flight deals from Harrisburg to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:17 pm -
1 stop4h 49m
Sat 12/126:02 am -
1 stop4h 25m
Deal found 10/17![American Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:15 am -
1 stop4h 55m
Sun 11/227:30 am -
1 stop4h 54m
Deal found 10/16![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop4h 25m
Sun 11/226:40 am -
1 stop3h 49m
Deal found 10/19![Delta logo]()
$389
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/47:43 am -
1 stop5h 40m
Tue 2/95:57 am -
1 stop6h 55m
Deal found 10/17![American Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:15 am -
1 stop4h 55m
Thu 11/195:00 am -
1 stop7h 24m
Deal found 10/15![United Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:03 am -
1 stop5h 39m
Thu 12/315:05 am -
2 stops12h 43m
Deal found 10/16![United Airlines logo]()
$560
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2510:35 am -
2 stops11h 37m
Tue 3/28:25 am -
1 stop4h 24m
Deal found 10/16![United Airlines logo]()
$570
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/46:20 am -
2 stops11h 53m
Tue 2/97:29 am -
1 stop5h 01m
Deal found 10/18![United Airlines logo]()
$606
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:15 am -
1 stop4h 55m
Mon 11/235:00 am -
2 stops12h 36m
Deal found 10/18![United Airlines logo]()
$660
Last-minute flights from Harrisburg to St. LouisDiscover last-minute flight deals from Harrisburg to St. Louis. Data last updated October 20, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to St. Louis. Data last updated October 20, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:08 am -
1 stop5h 42m
Sun 10/256:00 am -
1 stop4h 42m
Deal found 10/15![American Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:30 am -
1 stop6h 40m
Tue 11/38:00 am -
1 stop4h 58m
Deal found 10/15![United Airlines logo]()
$469
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:09 pm -
1 stop5h 10m
Sun 11/16:02 am -
1 stop6h 27m
Deal found 10/16![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:15 am -
1 stop4h 55m
Tue 11/101:08 pm -
1 stop7h 25m
Deal found 10/15![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:15 pm -
1 stop6h 07m
Mon 11/231:14 pm -
1 stop5h 11m
Deal found 10/15![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:15 am -
1 stop4h 55m
Thu 11/195:00 am -
1 stop7h 24m
Deal found 10/15![United Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:15 am -
1 stop4h 55m
Mon 11/161:08 pm -
1 stop4h 49m
Deal found 10/16![United Airlines logo]()
$345
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop4h 25m
Sun 11/226:40 am -
1 stop3h 49m
Deal found 10/19![Delta logo]()
$389
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:30 am -
1 stop5h 02m
Fri 11/2710:53 am -
1 stop7h 04m
Deal found 10/18![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:55 pm -
1 stop5h 06m
Sat 11/286:02 am -
1 stop6h 30m
Deal found 10/18![American Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:03 am -
1 stop7h 11m
Mon 11/3011:14 am -
1 stop7h 11m
Deal found 10/17![American Airlines logo]()
$399
One-way flights from Harrisburg to St. LouisSearch for one-way flight options from Harrisburg to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
Search for one-way flight options from Harrisburg to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:12 pm -
1 stop28h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Multiple Airlines logo]()
$160
This United Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/275:41 pm -
1 stop6h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![United Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/277:45 pm -
3 stops42h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Multiple Airlines logo]()
$561
Find flight deals from Harrisburg to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $321 (American Airlines) |
One-way from | $160 (Kiwi.com) |
Popular in | August |
Cheapest in | January |
Average price | $633 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
Use the filters below to find and compare flights from Harrisburg to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sun 12/6
9:12 pm-12:12 am
1 stop28h 00m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$160
Quickest round-trip
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Fri 11/27
5:41 pm-11:24 pm
1 stop6h 43m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sat 12/5
3:17 pm-7:06 pm
1 stop4h 49m
Lambert-St Louis
Sat 12/12
6:02 am-11:27 am
1 stop4h 25m
$321
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Thu 2/4
7:43 am-12:23 pm
1 stop5h 40m
Lambert-St Louis
Tue 2/9
5:57 am-1:52 pm
1 stop6h 55m
$330
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sun 11/15
8:15 am-12:10 pm
1 stop4h 55m
Lambert-St Louis
Sun 11/22
7:30 am-1:24 pm
1 stop4h 54m
$339
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Thu 11/12
8:15 am-12:10 pm
1 stop4h 55m
Lambert-St Louis
Thu 11/19
5:00 am-1:24 pm
1 stop7h 24m
$351
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Thu 11/19
6:00 am-9:25 am
1 stop4h 25m
Lambert-St Louis
Sun 11/22
6:40 am-11:29 am
1 stop3h 49m
$389
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sat 12/26
6:03 am-10:42 am
1 stop5h 39m
Lambert-St Louis
Thu 12/31
5:05 am-6:48 pm
2 stops12h 43m
$560
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Thu 2/25
10:35 am-9:12 pm
2 stops11h 37m
Lambert-St Louis
Tue 3/2
8:25 am-1:49 pm
1 stop4h 24m
$570
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Thu 2/4
6:20 am-5:13 pm
2 stops11h 53m
Lambert-St Louis
Tue 2/9
7:29 am-1:30 pm
1 stop5h 01m
$606
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Harrisburg to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to St. Louis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Harrisburg with our price prediction graph.
MDT-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to St. Louis
What is the cheapest month to book a flight from Harrisburg to St. Louis?
Currently, January is the cheapest month in which you can book a flight from Harrisburg to St. Louis (average of $304). Flying from Harrisburg to St. Louis in August is currently the most expensive (average of $708). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Harrisburg to St. Louis?
Airfare is below average for this route at the moment.
Harrisburg to St. Louis flights typically cost between $324 and $710 in December.The cheapest round-trip price found within the last 5 days was $321 on American Airlines (Dec 2-Dec 5).
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 20, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Harrisburg to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Overall
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Overall
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Overall
7.8
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Chesterfield
Collinsville
Edwardsville
Glencoe
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Alternative routes for Harrisburg to St. Louis
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Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Harrisburg to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Harrisburg and St. Louis flights
Browse other Harrisburg and St. Louis flight options. Last updated on October 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 20, 2026.
Top 3 airlines flying from Harrisburg to St. Louis
Discover the top 3 airlines that operate flights from Harrisburg to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$397 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$287 | Average$392 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$304 | Average$486 | FlexibilityNo cancel fee | On-time69% |