$284+ Cheap flights from Harrisburg to St. Louis (MDT - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — STL
Nov 4 — Nov 111
Round-trip
1 adult, Economy
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Find cheap flights from Harrisburg to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Harrisburg to St. Louis
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Cheapest flights from Harrisburg to St. LouisExplore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 5, 2026.
Explore the most affordable flight options available from Harrisburg to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 5, 2026.
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:00 am -
1 stop4h 41m
Sat 11/711:23 am -
1 stop6h 59m
Deal found 10/1![American Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:42 am -
1 stop4h 56m
Tue 11/37:26 am -
1 stop6h 19m
Deal found 9/30![American Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:15 pm -
1 stop6h 07m
Sun 11/157:26 am -
1 stop5h 08m
Deal found 9/30![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:15 am -
1 stop4h 55m
Mon 11/161:08 pm -
1 stop4h 49m
Deal found 10/4![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:09 pm -
1 stop5h 10m
Mon 10/195:00 am -
1 stop5h 19m
Deal found 10/1![American Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:52 am -
1 stop5h 11m
Thu 1/711:34 am -
1 stop7h 18m
Deal found 9/30![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:08 am -
1 stop5h 42m
Tue 10/136:00 am -
1 stop7h 10m
Deal found 9/30![American Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/268:19 pm -
1 stop5h 01m
Thu 12/314:32 pm -
1 stop4h 59m
Deal found 9/30![American Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:08 am -
1 stop5h 42m
Sun 10/1111:21 am -
1 stop6h 33m
Deal found 10/4![American Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:10 pm -
1 stop4h 25m
Sun 10/46:40 am -
1 stop3h 55m
Deal found 10/1![Delta logo]()
$459
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:55 pm -
1 stop5h 06m
Sat 11/287:26 am -
1 stop6h 18m
Deal found 10/1![American Airlines logo]()
$468
Best flights from Harrisburg to St. LouisDiscover carefully curated flight deals from Harrisburg to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 5, 2026.
Discover carefully curated flight deals from Harrisburg to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 5, 2026.
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/47:43 am -
1 stop5h 40m
Tue 2/95:57 am -
1 stop6h 55m
Deal found 10/2![American Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:15 am -
1 stop4h 55m
Mon 11/161:08 pm -
1 stop4h 49m
Deal found 10/4![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:08 am -
1 stop5h 42m
Sun 10/255:00 am -
1 stop5h 17m
Deal found 10/2![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:30 am -
1 stop6h 43m
Sat 10/2410:27 am -
1 stop5h 25m
Deal found 10/5![United Airlines logo]()
$469
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:30 am -
2 stops12h 10m
Sun 11/157:30 am -
1 stop4h 54m
Deal found 9/30![United Airlines logo]()
$532
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/410:35 am -
2 stops9h 48m
Tue 2/99:22 am -
1 stop6h 36m
Deal found 9/30![United Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:00 am -
1 stop5h 42m
Thu 12/315:20 am -
2 stops12h 28m
Deal found 10/3![United Airlines logo]()
$603
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/310:35 am -
2 stops11h 37m
Sun 3/77:00 am -
1 stop5h 32m
Deal found 10/1![United Airlines logo]()
$706
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:54 pm -
1 stop4h 27m
Mon 10/195:36 pm -
2 stops19h 23m
Deal found 10/1![United Airlines logo]()
$708
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:30 am -
2 stops12h 10m
Sat 11/281:08 pm -
1 stop4h 54m
Deal found 10/2![United Airlines logo]()
$733
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:54 pm -
1 stop4h 27m
Sun 10/257:30 am -
2 stops10h 06m
Deal found 10/2![United Airlines logo]()
$752
Last-minute flights from Harrisburg to St. LouisDiscover last-minute flight deals from Harrisburg to St. Louis. Data last updated October 5, 2026 and is based on user searches.
Discover last-minute flight deals from Harrisburg to St. Louis. Data last updated October 5, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:10 pm -
1 stop4h 25m
Sun 10/46:40 am -
1 stop3h 55m
Deal found 10/1![Delta logo]()
$459
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:08 am -
1 stop5h 42m
Tue 10/136:00 am -
1 stop7h 10m
Deal found 9/30![American Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:08 am -
1 stop5h 42m
Sun 10/1111:21 am -
1 stop6h 33m
Deal found 10/4![American Airlines logo]()
$444
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:09 pm -
1 stop5h 10m
Mon 10/195:00 am -
1 stop5h 19m
Deal found 10/1![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:54 pm -
1 stop6h 05m
Tue 10/208:00 am -
1 stop4h 27m
Deal found 10/1![United Airlines logo]()
$469
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:54 pm -
1 stop4h 27m
Mon 10/261:08 pm -
1 stop4h 49m
Deal found 10/1![United Airlines logo]()
$498
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:42 am -
1 stop4h 56m
Tue 11/37:26 am -
1 stop6h 19m
Deal found 9/30![American Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:00 am -
1 stop4h 41m
Sat 11/711:23 am -
1 stop6h 59m
Deal found 10/1![American Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:15 pm -
1 stop6h 07m
Sun 11/157:26 am -
1 stop5h 08m
Deal found 9/30![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:15 am -
1 stop4h 55m
Mon 11/161:08 pm -
1 stop4h 49m
Deal found 10/4![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:55 pm -
1 stop5h 06m
Sat 11/287:26 am -
1 stop6h 18m
Deal found 10/1![American Airlines logo]()
$468
One-way flights from Harrisburg to St. LouisSearch for one-way flight options from Harrisburg to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 5, 2026.
Search for one-way flight options from Harrisburg to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 5, 2026.
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:20 am -
1 stop4h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![United Airlines logo]()
$284
This KAYAK deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/127:06 pm -
1 stop4h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![American Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:56 pm -
2 stops28h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Multiple Airlines logo]()
$378
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:30 am -
1 stop5h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![United Airlines logo]()
$423
Find flight deals from Harrisburg to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Harrisburg (MDT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $321 (American Airlines) |
One-way from | $284 (United Airlines) |
Popular in | August |
Cheapest in | January |
Average price | $398 |
Cheapflights Fare Finder
Customize your flight search to find flights from Harrisburg to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 5, 2026.
Use the filters below to find and compare flights from Harrisburg to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sat 12/12
6:20 am-10:03 am
1 stop4h 43m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Sat 12/12
8:26 pm-12:02 am
1 stop4h 36m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Fri 12/11
6:17 am-10:30 am
1 stop5h 13m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$284
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Thu 2/4
7:43 am-12:23 pm
1 stop5h 40m
Lambert-St Louis
Tue 2/9
5:57 am-1:52 pm
1 stop6h 55m
$330
Quickest round-trip
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Mon 10/12
7:06 pm-10:14 pm
1 stop4h 08m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$331
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Fri 10/23
6:08 am-10:50 am
1 stop5h 42m
Lambert-St Louis
Sun 10/25
5:00 am-11:17 am
1 stop5h 17m
$339
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Fri 11/13
8:15 am-12:10 pm
1 stop4h 55m
Lambert-St Louis
Mon 11/16
1:08 pm-6:57 pm
1 stop4h 49m
$354
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Fri 10/16
3:56 pm-6:57 pm
2 stops28h 01m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$378
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Tue 10/20
6:30 am-12:13 pm
1 stop6h 43m
Lambert-St Louis
Sat 10/24
10:27 am-4:52 pm
1 stop5h 25m
$469
HarrisburgSt. Louis
MDT Harrisburg - STL Lambert-St Louis
MDTSTL
Harrisburg
Thu 11/12
10:30 am-9:40 pm
2 stops12h 10m
Lambert-St Louis
Sun 11/15
7:30 am-1:24 pm
1 stop4h 54m
$532
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Harrisburg to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Harrisburg to St. Louis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Harrisburg-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Harrisburg-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Harrisburg-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Harrisburg-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Harrisburg-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Harrisburg to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Harrisburg with our price prediction graph.
MDT-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Harrisburg to St. Louis
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 5, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Harrisburg to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.8
Entertainment
7.8
Boarding
8.1
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Harrisburg to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Chesterfield
Maryland Heights
Collinsville
Edwardsville
Glencoe
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Harrisburg and St. Louis flights
Browse other Harrisburg and St. Louis flight options. Last updated on October 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 5, 2026.
Top 3 airlines flying from Harrisburg to St. Louis
Discover the top 3 airlines that operate flights from Harrisburg to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$462 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$393 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$287 | Average$398 | FlexibilityNo cancel fee | On-timeN/A |