HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
St. Louis

$79+ Cheap flights from Charleston to St. Louis (CHS - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to St. Louis

Cheapest flights from Charleston to St. Louis
Explore the most affordable flight options available from Charleston to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:10 amCHS - STL
1 stop4h 25mAmerican Airlines
Tue 1/63:40 pmSTL - CHS
1 stop5h 54mAmerican Airlines
Deal found 12/11$378
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/232:59 pmCHS - STL
1 stop8h 34mMultiple Airlines
Tue 1/65:11 pmSTL - CHS
2 stops45h 59mMultiple Airlines
Deal found 12/11$382
This Kiwi.com deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:59 pmCHS - STL
1 stop8h 34mMultiple Airlines
Sun 12/2810:57 amSTL - CHS
2 stops33h 26mMultiple Airlines
Deal found 12/10$405
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:08 pmCHS - STL
1 stop4h 48mAmerican Airlines
Tue 12/306:00 pmSTL - CHS
1 stop5h 45mAmerican Airlines
Deal found 12/9$436
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:10 amCHS - STL
1 stop4h 25mAmerican Airlines
Tue 12/306:35 pmSTL - CHS
1 stop4h 30mAmerican Airlines
Deal found 12/10$443
This Southwest deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:10 amCHS - STL
2 stops7h 50mSouthwest
Tue 1/68:20 amSTL - CHS
2 stops9h 50mSouthwest
Deal found 12/11$445
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:00 amCHS - STL
1 stop3h 54mDelta
Thu 12/251:22 pmSTL - CHS
1 stop5h 09mDelta
Deal found 12/11$507
This KAYAK deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:25 amCHS - STL
1 stop6h 20mDelta
Thu 12/186:05 amSTL - CHS
1 stop6h 57mDelta
Deal found 12/10$533
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:49 pmCHS - STL
2 stops36h 58mMultiple Airlines
Mon 12/159:54 amSTL - CHS
1 stop21h 43mMultiple Airlines
Deal found 12/9$535

Find flight deals from Charleston to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$208
(Kiwi.com)

One-way from

$79
(Kiwi.com)

Popular in

February

Cheapest in

September

Average price

$384
Provider with most accurate pricing for Charleston-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Lambert-St Louis flights.
Search Deals
From Charleston to Lambert-St Louis
Search Deals
One-way flight from Charleston to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Charleston to St. Louis that are best for you.

Fly from

Charleston

Fly to

St. Louis

Route

Depart

Return

Price

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 1/22

3:01 pm-10:23 am

1 stop20h 22m

Lambert-St Louis

Sun 1/25

5:42 pm-5:36 pm

2 stops22h 54m

$208

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Sat 1/17

6:35 pm-9:11 am

2 stops15h 36m

Lambert-St Louis

Mon 1/19

5:11 pm-8:38 am

1 stop14h 27m

$249

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Fri 1/16

6:05 am-10:34 pm

2 stops17h 29m

Lambert-St Louis

Mon 1/19

5:11 pm-8:38 am

1 stop14h 27m

$293

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Tue 1/13

6:30 am-11:05 am

1 stop5h 35m

Lambert-St Louis

Sat 1/17

5:00 pm-11:55 pm

1 stop5h 55m

$325

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Sat 1/17

2:58 pm-7:27 pm

1 stop5h 29m

Lambert-St Louis

Mon 1/19

12:44 pm-7:04 pm

1 stop5h 20m

$337

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Sat 1/17

6:45 am-1:50 pm

2 stops8h 05m

Lambert-St Louis

Mon 1/19

8:10 am-9:40 pm

2 stops12h 30m

$353

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Fri 2/13

5:27 am-9:06 am

1 stop4h 39m

Lambert-St Louis

Tue 2/17

1:10 pm-8:45 pm

1 stop6h 35m

$353

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Sun 1/11

2:44 pm-5:50 pm

1 stop4h 06m

Lambert-St Louis

Tue 1/13

7:10 am-1:37 pm

1 stop5h 27m

$353

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 1/15

7:00 pm-11:59 pm

1 stop5h 59m

Lambert-St Louis

Sun 1/18

8:05 am-2:02 pm

1 stop4h 57m

$365

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 1/15

5:25 am-11:05 am

1 stop6h 40m

Lambert-St Louis

Sun 1/18

6:10 am-2:18 pm

1 stop7h 08m

$365

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 16 results
1
2

Compare providers for flights from Charleston to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to St. Louis in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Charleston-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Charleston-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to St. Louis

What is the cheapest month to book a flight from Charleston to St. Louis?

Currently, June is the cheapest month in which you can book a flight from Charleston to St. Louis (average of $128). Flying from Charleston to St. Louis in February is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to STL?

Find hourly flight availability from Charleston to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Charleston to St. Louis in the afternoon. If you’re flexible enough to do this you can expect to save up to 36% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Charleston to St. Louis?

Use this chart to determine the cheapest time to fly round-trip from Charleston to St. Louis. Price data was last updated on December 6, 2025.

Travelers seeking maximum savings on their Charleston to St. Louis flight should consider departing on Saturday at noon when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated December 12, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Charleston to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,253 reviews
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,050 reviews
Southwest
7.9
Good
4,253 reviews

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Charleston to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Charleston to St. Louis flight route?

    Flights from Charleston to Lambert-St Louis have been viewed 9 times in the past calendar month.

  • How long is the flight from Charleston to St. Louis?

    Departing from Charleston to St. Louis will take you 5h 29m. Airlines will cover a distance of 705 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Charleston to St. Louis round-trip?

    Our cheapest airline available from Charleston to St. Louis is Southwest. Our recent data shows that you can find tickets from as low as $287 on this airline. Additional options worth looking into are American Airlines and Delta, starting at $296 and $306 round-trip. You may be able to fly from Charleston to St. Louis for 29% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Charleston to St. Louis one-way?

    One-way options have recently been found by users for as low as $113 on Delta. Other airlines that offer cheap prices include American Airlines from $118 and Southwest from $143 one-way.

  • Can I find deals for flights from Charleston to St. Louis that include hotel bookings?

    Yes. In addition to deals on Charleston to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to St. Louis.

  • Can I find deals for business class flights from Charleston to St. Louis?

    Yes. Cheapflights offers flight deals from Charleston to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to St. Louis?

    Currently, June is the cheapest month in which you can book a flight from Charleston to St. Louis (average of $128). Flying from Charleston to St. Louis in February is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Swansea
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to St. Louis flights
Charlotte to Kansas City flights
Columbia to Kansas City flights
Charlotte to Joplin flights
Charlotte to Springfield flights
Charleston to Kansas City flights
Savannah to St. Louis flights
Myrtle Beach to St. Louis flights
Greenville to Kansas City flights
Augusta to Kansas City flights
Savannah to Springfield flights
Greenville to St. Louis flights
Savannah to Kansas City flights
Myrtle Beach to Kansas City flights
Columbia to St. Louis flights
Charleston to Springfield flights
Columbia to Springfield flights
Greenville to Springfield flights
Myrtle Beach to Springfield flights
Charleston to Columbia flights
Charlotte to Columbia flights
Augusta to St. Louis flights
Myrtle Beach to Joplin flights
Columbia to Columbia flights
Florence to Kansas City flights
Hilton Head Island to Kansas City flights
Hilton Head Island to St. Louis flights
Augusta to Columbia flights
Florence to St. Louis flights
Charlotte to Fort Leonard Wood flights

Top 3 airlines flying from Charleston to St. Louis

Discover the top 3 airlines that operate flights from Charleston to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$287Average$373FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$296Average$430FlexibilityNo cancel feeOn-time71%
DeltaCheapest$306Average$385FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.