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$161+ Cheap flights from Buffalo to St. Louis (BUF - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/18. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Buffalo to St. Louis

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:52 pmBUF - STL
1 stop3h 49mDelta
Mon 12/295:13 pmSTL - BUF
1 stop5h 34mDelta
Deal found 12/9$335
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:29 amBUF - STL
2 stops6h 58mUnited Airlines
Mon 12/293:10 pmSTL - BUF
1 stop4h 44mUnited Airlines
Deal found 12/9$413
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:29 pmBUF - STL
1 stop6h 26mAmerican Airlines
Tue 12/306:35 pmSTL - BUF
1 stop4h 24mAmerican Airlines
Deal found 12/11$447
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:30 amBUF - STL
1 stop6h 57mUnited Airlines
Tue 12/306:30 amSTL - BUF
2 stops6h 44mUnited Airlines
Deal found 12/11$466
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:54 pmBUF - STL
1 stop5h 48mDelta
Tue 12/305:59 pmSTL - BUF
1 stop4h 29mDelta
Deal found 12/11$512
This Southwest deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:20 amBUF - STL
2 stops8h 25mSouthwest
Tue 12/304:50 pmSTL - BUF
1 stop5h 45mSouthwest
Deal found 12/11$517
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:04 amBUF - STL
1 stop7h 10mAmerican Airlines
Sun 12/148:38 amSTL - BUF
1 stop6h 22mAmerican Airlines
Deal found 12/11$757
This Southwest deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:45 amBUF - STL
2 stops8h 50mSouthwest
Sun 12/1411:00 amSTL - BUF
2 stops10h 10mSouthwest
Deal found 12/11$767

Find flight deals from Buffalo to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$295
(Kiwi.com)

One-way from

$161
(Frontier)

Popular in

January

Cheapest in

September

Average price

$396
Provider with most accurate pricing for Buffalo-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Lambert-St Louis flights.
Search Deals
From Buffalo to Lambert-St Louis
Search Deals
One-way flight from Buffalo to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($39 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Fly from

Buffalo

Fly to

St. Louis

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 3/6

9:25 pm-7:07 am

1 stop10h 42m

Lambert-St Louis

Sun 3/8

7:42 am-8:30 pm

1 stop11h 48m

$297

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 1/18

8:30 am-12:29 pm

1 stop4h 59m

Lambert-St Louis

Thu 1/22

12:44 pm-7:25 pm

1 stop5h 41m

$335

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 12/25

5:52 pm-8:41 pm

1 stop3h 49m

Lambert-St Louis

Mon 12/29

5:13 pm-11:47 pm

1 stop5h 34m

$335

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 2/15

5:24 pm-9:52 pm

1 stop5h 28m

Lambert-St Louis

Thu 2/19

7:01 am-3:23 pm

1 stop7h 22m

$347

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 2/15

1:05 pm-8:10 pm

1 stop8h 05m

Lambert-St Louis

Thu 2/19

9:40 am-9:35 pm

2 stops10h 55m

$409

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 12/25

10:29 am-4:27 pm

2 stops6h 58m

Lambert-St Louis

Mon 12/29

3:10 pm-8:54 pm

1 stop4h 44m

$413

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 12/18

2:07 pm-10:33 pm

1 stop9h 26m

$161

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 12/31

5:35 pm-10:43 pm

1 stop6h 08m

$168

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 3/26

4:57 pm-11:42 pm

1 stop7h 45m

$184

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 3/26

6:15 pm-12:40 am

1 stop7h 25m

$184

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 15 results
1
2

Compare providers for flights from Buffalo to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to St. Louis in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $112). Flying from Buffalo to St. Louis in February is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to STL?

Find hourly flight availability from Buffalo to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

One of the essential ways to save on airfare from Buffalo to St. Louis is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 21% on airfare.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated December 12, 2025.
Read through reviews of airlines operating flights from Buffalo to St. Louis, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,253 reviews
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,095 reviews
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,050 reviews
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to St. Louis?

    There are many flights that can get you from Buffalo to St. Louis in 3h 49m. Fly via Frontier, United Airlines, or Delta to get the fastest option. There are 672 mi between Buffalo and St. Louis. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Buffalo to St. Louis round-trip?

    Our cheapest airline available from Buffalo to St. Louis is Delta. Our recent data shows that you can find tickets from as low as $164 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $243 and $296 round-trip. Delta is currently priced 54% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Buffalo to St. Louis one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $95. Southwest flights start at $119 while deals on Delta start at $125 one-way.

  • Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

    Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

  • Can I find deals for business class flights from Buffalo to St. Louis?

    Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $112). Flying from Buffalo to St. Louis in February is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Swansea
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

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Top 4 airlines flying from Buffalo to St. Louis

Discover the top 4 airlines that operate flights from Buffalo to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$164Average$346FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$243Average$338FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$296Average$517FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$338Average$467FlexibilityNo cancel feeOn-time63%

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