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$117+ Cheap flights from Buffalo to St. Louis (BUF - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheapflights Tip: The best prices from Buffalo to Lambert-St Louis are usually found in September or July, booked 35 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Buffalo to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$225
(FlightHub)

One-way from

$117
(FlightHub)

Popular in

March

Cheapest in

September

Average price

$326
From Buffalo to Lambert-St Louis
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One-way flight from Buffalo to Lambert-St Louis
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Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Buffalo to St. Louis

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/12:11 pmBUF - STL
1 stop20h 00mFrontier
Sun 8/312:02 pmSTL - BUF
1 stop18h 25mFrontier
Deal found 7/27$225
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/221:14 pmBUF - STL
1 stop6h 32mAmerican Airlines
Sat 10/254:34 pmSTL - BUF
1 stop6h 01mAmerican Airlines
Deal found 7/28$237
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/224:15 pmBUF - STL
2 stops6h 50mSouthwest
Sat 10/253:35 pmSTL - BUF
1 stop6h 15mSouthwest
Deal found 7/28$242
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/127:00 amBUF - STL
1 stop6h 27mUnited Airlines
Sat 8/166:33 amSTL - BUF
2 stops6h 39mUnited Airlines
Deal found 7/28$518
This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/712:11 pmBUF - STL
3 stops22h 41mMultiple Airlines
Sun 8/1010:47 amSTL - BUF
2 stops22h 57mMultiple Airlines
Deal found 7/28$659

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Fly from

Buffalo

Fly to

St. Louis

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 9/4

7:41 pm-1:02 pm

1 stop18h 21m

Lambert-St Louis

Sun 9/7

1:52 pm-6:14 pm

1 stop27h 22m

$225

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 10/22

1:14 pm-6:46 pm

1 stop6h 32m

Lambert-St Louis

Sat 10/25

4:34 pm-11:35 pm

1 stop6h 01m

$237

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 10/22

4:15 pm-10:05 pm

2 stops6h 50m

Lambert-St Louis

Sat 10/25

3:35 pm-10:50 pm

1 stop6h 15m

$242

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 8/12

7:00 am-12:27 pm

1 stop6h 27m

Lambert-St Louis

Sat 8/16

6:33 am-2:12 pm

2 stops6h 39m

$518

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 9/1

4:55 pm-9:11 am

1 stop17h 16m

$117

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 11/18

6:00 am-11:02 am

1 stop6h 02m

$119

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 11/18

2:55 pm-10:45 pm

2 stops8h 50m

$159

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 8/7

4:25 pm-10:35 pm

2 stops7h 10m

$269

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 8/7

12:11 pm-9:52 am

3 stops22h 41m

$336

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

How far ahead should I book a flight from Buffalo to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Buffalo to St. Louis. Price data was last updated on July 25, 2025.

The best time to book flights from Buffalo to St. Louis is 35 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $311). Flying from Buffalo to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to STL?

Find hourly flight availability from Buffalo to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

One of the essential ways to save on airfare from Buffalo to St. Louis is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 22% on airfare.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 29, 2025.
Read through reviews of airlines operating flights from Buffalo to St. Louis, such as Southwest, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,896 reviews
Southwest
8.0
Very good
4,238 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,238 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Frontier
5.9
Fair
3,238 reviews
Southwest
8.0
Very good
4,238 reviews

Food

7.0

Overall

8.0

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Buffalo to St. Louis round-trip?

    Our cheapest airline available from Buffalo to St. Louis is Frontier. Our recent data shows that you can find tickets from as low as $225 on this airline. Additional options worth looking into are American Airlines and Southwest, starting at $237 and $242 round-trip. Frontier is currently priced 36% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Buffalo to St. Louis one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $117. American Airlines flights start at $119 while deals on United Airlines start at $159 one-way.

  • Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

    Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

  • Can I find deals for business class flights from Buffalo to St. Louis?

    Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $311). Flying from Buffalo to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
O'Fallon
Maryland Heights
Fairview Heights
Collinsville
Eureka
St. Peters
Glencoe
Alton
Chesterfield
Festus
Farmington

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Alternative routes for Buffalo to St. Louis

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Top 3 airlines flying from Buffalo to St. Louis

Discover the top 3 airlines that operate flights from Buffalo to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$246Average$346FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$357FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$301Average$416FlexibilityNo cancel feeOn-time63%

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