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$77+ Cheap flights from Buffalo to St. Louis (BUF - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Buffalo to Lambert-St Louis are usually found in September or July, booked 35 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Buffalo to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$224
(American Airlines)

One-way from

$77
(Southwest)

Popular in

October

Cheapest in

September

Average price

$296
From Buffalo to Lambert-St Louis
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One-way flight from Buffalo to Lambert-St Louis
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High demand for flights, 4% potential price rise
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Cheapest flight prices on average. 0% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Buffalo to St. Louis

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:00 amBUF - STL
1 stop4h 56mAmerican Airlines
Mon 10/274:34 pmSTL - BUF
1 stop6h 01mAmerican Airlines
Deal found 9/11$224
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/25:20 amBUF - STL
1 stop4h 17mDelta
Wed 11/55:15 pmSTL - BUF
1 stop5h 24mDelta
Deal found 9/10$246
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/167:40 amBUF - STL
1 stop9h 32mAmerican Airlines
Thu 11/205:00 amSTL - BUF
1 stop5h 02mAmerican Airlines
Deal found 9/10$248
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:00 amBUF - STL
1 stop7h 23mAmerican Airlines
Fri 10/36:10 amSTL - BUF
1 stop3h 56mAmerican Airlines
Deal found 9/11$251
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:00 amBUF - STL
1 stop7h 23mAmerican Airlines
Tue 9/306:00 pmSTL - BUF
1 stop4h 55mAmerican Airlines
Deal found 9/11$253
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:40 amBUF - STL
1 stop7h 00mAmerican Airlines
Sun 11/97:58 pmSTL - BUF
1 stop12h 39mAmerican Airlines
Deal found 9/11$261
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/107:07 amBUF - STL
1 stop4h 42mUnited Airlines
Sun 10/125:00 amSTL - BUF
1 stop3h 53mUnited Airlines
Deal found 9/11$263
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:00 amBUF - STL
1 stop7h 23mAmerican Airlines
Mon 10/66:08 pmSTL - BUF
1 stop4h 34mAmerican Airlines
Deal found 9/11$274
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:45 pmBUF - STL
1 stop5h 22mAmerican Airlines
Sat 10/42:11 pmSTL - BUF
1 stop6h 42mAmerican Airlines
Deal found 9/11$287
This Frontier deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/22:42 pmBUF - STL
2 stops19h 58mFrontier
Wed 11/57:45 pmSTL - BUF
2 stops18h 43mFrontier
Deal found 9/10$296
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:00 amBUF - STL
1 stop7h 23mAmerican Airlines
Sun 10/56:00 pmSTL - BUF
1 stop4h 55mAmerican Airlines
Deal found 9/11$299

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Fly from

Buffalo

Fly to

St. Louis

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 11/2

5:20 am-8:37 am

1 stop4h 17m

Lambert-St Louis

Wed 11/5

5:15 pm-11:39 pm

1 stop5h 24m

$246

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 11/16

7:40 am-4:12 pm

1 stop9h 32m

Lambert-St Louis

Thu 11/20

5:00 am-11:02 am

1 stop5h 02m

$248

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 2/26

6:50 pm-11:40 pm

1 stop5h 50m

Lambert-St Louis

Sun 3/1

6:45 am-11:51 am

1 stop4h 06m

$250

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 9/30

6:00 am-12:23 pm

1 stop7h 23m

Lambert-St Louis

Fri 10/3

6:10 am-11:06 am

1 stop3h 56m

$251

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 9/30

6:00 am-12:23 pm

1 stop7h 23m

Lambert-St Louis

Wed 10/1

2:11 pm-9:43 pm

1 stop6h 32m

$253

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 10/10

7:07 am-10:49 am

1 stop4h 42m

Lambert-St Louis

Sun 10/12

5:00 am-9:53 am

1 stop3h 53m

$263

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 11/3

5:40 pm-10:45 pm

1 stop6h 05m

Lambert-St Louis

Wed 11/5

11:05 am-4:48 pm

1 stop4h 43m

$274

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 9/30

5:38 am-10:21 am

1 stop5h 43m

Lambert-St Louis

Thu 10/2

6:05 am-11:06 am

1 stop4h 01m

$274

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 11/2

2:42 pm-9:40 am

2 stops19h 58m

Lambert-St Louis

Wed 11/5

7:45 pm-3:28 pm

2 stops18h 43m

$296

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 9/30

6:00 am-1:09 pm

2 stops8h 09m

Lambert-St Louis

Tue 9/30

6:00 pm-11:55 pm

1 stop4h 55m

$304

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 19 results
1
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Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

How far ahead should I book a flight from Buffalo to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Buffalo to St. Louis. Price data was last updated on August 29, 2025.

The best time to book flights from Buffalo to St. Louis is 35 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $311). Flying from Buffalo to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to STL?

Find hourly flight availability from Buffalo to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

One of the essential ways to save on airfare from Buffalo to St. Louis is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 22% on airfare.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Buffalo to St. Louis, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to St. Louis?

    There are many flights that can get you from Buffalo to St. Louis in 4h 17m. Fly via Delta or American Airlines to get the fastest option. There are 672 mi between Buffalo and St. Louis. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Buffalo to St. Louis round-trip?

    Our cheapest airline available from Buffalo to St. Louis is American Airlines. Our recent data shows that you can find tickets from as low as $236 on this airline. Additional options worth looking into are Delta and Southwest, starting at $243 and $301 round-trip. American Airlines is currently priced 34% below the average price you’ll pay for this route.

  • Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

    Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

  • Can I find deals for business class flights from Buffalo to St. Louis?

    Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $311). Flying from Buffalo to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

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Alternative routes for Buffalo to St. Louis

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Top 3 airlines flying from Buffalo to St. Louis

Discover the top 3 airlines that operate flights from Buffalo to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$376FlexibilityNo cancel feeOn-time71%
DeltaCheapest$243Average$346FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$301Average$426FlexibilityNo cancel feeOn-time63%

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