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$216+ Cheap flights from South Carolina to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAD
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from South Carolina to Spain

Cheapest flights from South Carolina to Spain
Explore the most affordable flight options available from South Carolina to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:42 pm
CLT
-
BCN
2 stops32h 38m
Multiple Airlines
Tue 3/105:35 pm
BCN
-
CLT
1 stop31h 37m
Multiple Airlines
Deal found 1/26$467
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:30 am
GSP
-
BCN
2 stops20h 30m
United Airlines
Mon 3/21:35 pm
BCN
-
GSP
2 stops37h 06m
United Airlines
Deal found 1/26$470
This oojo deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/310:58 am
CHS
-
BCN
2 stops18h 22m
British Airways
Sun 3/810:20 am
BCN
-
CHS
1 stop18h 39m
British Airways
Deal found 1/26$473
This oojo deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:00 am
GSP
-
BCN
2 stops31h 45m
British Airways
Mon 3/212:30 pm
BCN
-
GSP
1 stop14h 16m
British Airways
Deal found 1/26$473
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/2310:00 am
CHS
-
MAD
2 stops17h 15m
United Airlines
Tue 3/31:35 pm
MAD
-
CHS
2 stops31h 14m
United Airlines
Deal found 1/26$474
This oojo deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2510:50 am
GSP
-
MAD
2 stops27h 15m
British Airways
Wed 3/41:15 pm
MAD
-
GSP
1 stop13h 31m
British Airways
Deal found 1/26$476
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:12 am
GSP
-
BCN
1 stop20h 48m
United Airlines
Tue 3/1710:30 am
BCN
-
GSP
1 stop13h 58m
United Airlines
Deal found 1/27$478
This Cheapflightsfares deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2512:05 pm
GSP
-
MAD
2 stops23h 45m
Lufthansa
Wed 3/45:55 am
MAD
-
GSP
2 stops19h 29m
Lufthansa
Deal found 1/26$479
This Cheapflightsfares deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:40 pm
CLT
-
BCN
1 stop17h 15m
Lufthansa
Wed 9/309:05 am
BCN
-
CLT
1 stop13h 40m
Lufthansa
Deal found 1/26$480
This Cheapflightsfares deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1812:07 pm
GSP
-
BCN
2 stops21h 38m
Lufthansa
Wed 3/257:40 am
BCN
-
GSP
2 stops21h 19m
Lufthansa
Deal found 1/26$480
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:40 pm
CLT
-
BCN
1 stop17h 15m
Lufthansa
Wed 10/79:05 am
BCN
-
CLT
1 stop13h 40m
Lufthansa
Deal found 1/27$481
This KLM deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:00 am
CHS
-
MAD
1 stop20h 00m
KLM
Wed 3/119:00 am
MAD
-
CHS
2 stops17h 54m
KLM
Deal found 1/27$483

Find flight deals from South Carolina to Spain

Keep the following information in mind while searching for South Carolina to Spain flight deals. Data was last updated January 28, 2026.

Round-trip from

$467
(Kiwi.com)

One-way from

$216
(oojo)

Popular in

May

Cheapest in

February

Average price

$637
From South Carolina to Spain
Search Deals
One-way flight from South Carolina to Spain
Search Deals
Highest demand for flights based on searches. 25% potential increase in price ($341 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($44 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from South Carolina to Spain that are best for you.

Fly from

South Carolina

Fly to

Spain

Route

Depart

Return

Price

GreenvilleMadrid

GSP - MAD

GSPMAD

Greenville

Wed 2/25

10:50 am-8:05 pm

2 stops27h 15m

Madrid Barajas

Wed 3/4

1:15 pm-8:46 pm

1 stop13h 31m

$476

GreenvilleBarcelona

GSP - BCN

GSPBCN

Greenville

Sun 3/1

6:12 am-9:00 am

1 stop20h 48m

Barcelona-El Prat

Tue 3/17

10:30 am-11:59 pm

2 stops18h 29m

$478

GreenvilleMadrid

GSP - MAD

GSPMAD

Greenville

Wed 2/25

12:05 pm-5:50 pm

2 stops23h 45m

Madrid Barajas

Wed 3/4

5:55 am-7:24 pm

2 stops19h 29m

$479

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Thu 2/26

6:00 am-8:00 am

1 stop20h 00m

Madrid Barajas

Wed 3/11

9:00 am-9:54 pm

2 stops17h 54m

$483

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Mon 2/23

4:29 pm-12:40 pm

2 stops14h 11m

Madrid Barajas

Tue 3/3

10:00 am-11:59 pm

1 stop19h 59m

$486

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Tue 4/7

8:09 pm-9:35 am

1 stop31h 26m

Madrid Barajas

Wed 4/15

12:20 pm-12:24 am

1 stop18h 04m

$492

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Thu 2/26

6:00 am-8:00 am

1 stop20h 00m

Madrid Barajas

Wed 3/11

9:00 am-11:55 pm

2 stops19h 55m

$494

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Sat 2/28

6:00 am-9:15 am

2 stops21h 15m

Madrid Barajas

Sat 3/7

11:15 am-12:52 pm

2 stops31h 37m

$505

GreenvilleBarcelona

GSP - BCN

GSPBCN

Greenville

Wed 3/18

10:00 am-4:20 pm

2 stops25h 20m

Barcelona-El Prat

Wed 3/25

10:30 am-7:28 pm

1 stop13h 58m

$505

CharlotteValencia

CLT - VLC

CLTVLC

Charlotte Douglas

Tue 2/24

1:11 pm-12:00 pm

2 stops16h 49m

Valencia

Tue 3/10

6:00 am-8:18 pm

2 stops19h 18m

$513

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Spain

What is the cheapest month to book a flight from South Carolina to Spain?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Spain (average of $354). Flying from South Carolina to Spain in June is currently the most expensive (average of $804). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Spain?

    A quick flight from South Carolina to Spain can take about 20h 48m. British Airways provides one of the quickest options available for as low as $478. The distance between South Carolina and Spain is about 4417 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from South Carolina to Spain that include hotel bookings?

    Yes. In addition to deals on South Carolina to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Spain.

  • Can I find deals for business class flights from South Carolina to Spain?

    Yes. Cheapflights offers flight deals from South Carolina to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Spain?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Spain (average of $354). Flying from South Carolina to Spain in June is currently the most expensive (average of $804). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Spain

Discover the top 6 airlines that operate flights from South Carolina to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$207Average$969FlexibilityNo cancel feeOn-timeN/A
Air FranceCheapest$433Average$1,081FlexibilityNo cancel feeOn-time77%
United AirlinesCheapest$482Average$827FlexibilityNo cancel feeOn-time69%
KLMCheapest$485Average$874FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$488Average$985FlexibilityNo cancel feeOn-time71%
British AirwaysCheapest$517Average$886FlexibilityNo cancel feeOn-time70%

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