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$218+ Cheap flights from South Carolina to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MAD
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from South Carolina to Spain

Keep the following information in mind while searching for South Carolina to Spain flight deals. Data was last updated October 30, 2025.

Round-trip from

$416
(Flighttix)

One-way from

$218
(American Airlines)

Popular in

March

Cheapest in

November

Average price

$1,100
From South Carolina to Spain
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One-way flight from South Carolina to Spain
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Highest demand for flights based on searches. 12% potential increase in price ($166 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($104 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from South Carolina to Spain

Cheapest flights from South Carolina to Spain
Explore the most affordable flight options available from South Carolina to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This KLM deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/13:47 pmCHS - MAD
1 stop11h 28mKLM
Tue 12/1610:00 amMAD - CHS
1 stop17h 01mKLM
Deal found 10/29$438
This Virgin Atlantic deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/112:51 pmCHS - MAD
1 stop14h 24mVirgin Atlantic
Tue 12/1610:00 amMAD - CHS
2 stops19h 50mVirgin Atlantic
Deal found 10/29$443
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:59 pmGSP - BCN
1 stop29h 16mDelta
Tue 1/2010:15 amBCN - GSP
2 stops29h 06mDelta
Deal found 10/28$444
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/175:16 pmGSP - MAD
1 stop9h 59mDelta
Tue 11/2511:00 amMAD - GSP
2 stops28h 02mDelta
Deal found 10/30$463
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:36 pmGSP - BCN
2 stops32h 44mUnited Airlines
Tue 1/201:35 pmBCN - GSP
2 stops37h 12mUnited Airlines
Deal found 10/30$466
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:35 pmCHS - BCN
2 stops17h 10mUnited Airlines
Tue 11/181:35 pmBCN - CHS
2 stops31h 34mUnited Airlines
Deal found 10/29$480
This Finnair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:00 amCHS - BCN
1 stop21h 00mMultiple Airlines
Tue 11/1811:00 amBCN - CHS
1 stop14h 17mMultiple Airlines
Deal found 10/30$484
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:15 amSAV - BCN
2 stops17h 20mUnited Airlines
Tue 12/231:35 pmBCN - SAV
2 stops51h 08mUnited Airlines
Deal found 10/28$484
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:39 amGSP - BCN
1 stop21h 21mAmerican Airlines
Tue 1/2010:40 amBCN - GSP
1 stop16h 16mAmerican Airlines
Deal found 10/28$484
This Finnair deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/38:00 amSAV - BCN
2 stops17h 05mMultiple Airlines
Tue 12/2312:30 pmBCN - SAV
1 stop14h 39mMultiple Airlines
Deal found 10/28$488
This British Airways deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:00 amGSP - MAD
1 stop20h 55mBritish Airways
Tue 11/251:15 pmMAD - GSP
1 stop13h 40mBritish Airways
Deal found 10/30$488
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:00 amGSP - MAD
2 stops20h 00mUnited Airlines
Fri 12/51:35 pmMAD - GSP
2 stops37h 14mUnited Airlines
Deal found 10/29$490

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from South Carolina to Spain that are best for you.

Fly from

South Carolina

Fly to

Spain

Route

Depart

Return

Price

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Mon 1/12

12:00 pm-8:00 am

1 stop14h 00m

Madrid Barajas

Thu 1/22

10:00 am-10:22 pm

1 stop18h 22m

$438

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Mon 12/1

3:47 pm-9:15 am

1 stop11h 28m

Madrid Barajas

Tue 12/16

10:00 am-9:01 pm

1 stop17h 01m

$438

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Mon 1/12

12:00 pm-8:00 am

1 stop14h 00m

Madrid Barajas

Tue 1/20

10:00 am-10:22 pm

1 stop18h 22m

$438

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Mon 1/12

6:00 am-8:00 am

1 stop20h 00m

Madrid Barajas

Wed 1/21

10:00 am-10:22 pm

1 stop18h 22m

$438

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Mon 1/19

12:00 pm-8:00 am

1 stop14h 00m

Madrid Barajas

Thu 1/29

10:00 am-5:13 pm

1 stop13h 13m

$438

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Mon 1/12

10:25 am-8:00 am

2 stops15h 35m

Madrid Barajas

Fri 1/23

10:00 am-5:13 pm

1 stop13h 13m

$443

CharlestonMadrid

CHS - MAD

CHSMAD

Charleston

Sun 1/11

5:53 pm-8:00 am

1 stop32h 07m

Madrid Barajas

Thu 1/22

10:00 am-5:13 pm

1 stop13h 13m

$443

GreenvilleBarcelona

GSP - BCN

GSPBCN

Greenville

Mon 12/29

5:36 pm-8:20 am

2 stops32h 44m

Barcelona-El Prat

Tue 1/20

1:35 pm-8:47 pm

2 stops37h 12m

$466

SavannahBarcelona

SAV - BCN

SAVBCN

Savannah/Hilton Head

Wed 12/3

10:57 am-7:05 am

1 stop14h 08m

Barcelona-El Prat

Tue 12/23

12:30 pm-9:09 pm

1 stop14h 39m

$484

GreenvilleBarcelona

GSP - BCN

GSPBCN

Greenville

Mon 12/29

5:39 am-9:00 am

1 stop21h 21m

Barcelona-El Prat

Tue 1/20

10:40 am-8:56 pm

1 stop16h 16m

$484

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Spain

What is the cheapest month to book a flight from South Carolina to Spain?

Currently, September is the cheapest month in which you can book a flight from South Carolina to Spain (average of $380). Flying from South Carolina to Spain in June is currently the most expensive (average of $804). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to ES?

Find hourly flight availability from South Carolina to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

When flying from South Carolina to Spain, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 18% versus a flight at noon.

What is the cheapest day to fly from South Carolina to Spain?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Spain. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Spain flight should consider departing on Tuesday evenings when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Spain?

    A quick flight from South Carolina to Spain can take about 11h 28m. Delta provides one of the quickest options available for as low as $438. The distance between South Carolina and Spain is about 4134 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from South Carolina to Spain one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $218. Users have also found prices from $233 and $405 on British Airways and Lufthansa, respectively.

  • Can I find deals for flights from South Carolina to Spain that include hotel bookings?

    Yes. In addition to deals on South Carolina to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Spain.

  • Can I find deals for business class flights from South Carolina to Spain?

    Yes. Cheapflights offers flight deals from South Carolina to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Spain?

    Currently, September is the cheapest month in which you can book a flight from South Carolina to Spain (average of $380). Flying from South Carolina to Spain in June is currently the most expensive (average of $804). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Spain

Discover the top 6 airlines that operate flights from South Carolina to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$207Average$1,076FlexibilityNo cancel feeOn-timeN/A
Air FranceCheapest$433Average$1,081FlexibilityNo cancel feeOn-time77%
United AirlinesCheapest$482Average$875FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$581Average$987FlexibilityNo cancel feeOn-time71%
British AirwaysCheapest$593Average$968FlexibilityNo cancel feeOn-time70%
KLMCheapest$650Average$896FlexibilityNo cancel feeOn-time75%

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