HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Spain

$416+ Cheap flights from Mississippi to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — MAD
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mississippi to Spain with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Mississippi to Spain

Cheapest flights from Mississippi to Spain
Explore the most affordable flight options available from Mississippi to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Air France deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/264:40 pmMEM - MAD
1 stop33h 25mMultiple Airlines
Tue 11/1111:15 amMAD - MEM
1 stop18h 49mMultiple Airlines
Deal found 10/15$429
This Air France deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/114:20 pmMEM - BCN
1 stop32h 40mKLM
Tue 11/2510:55 amBCN - MEM
1 stop16h 58mKLM
Deal found 10/16$439
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:02 amMOB - BCN
1 stop19h 38mDelta
Tue 12/96:00 amBCN - MOB
2 stops19h 32mDelta
Deal found 10/16$461
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/112:55 pmMEM - BCN
1 stop15h 15mUnited Airlines
Tue 11/251:35 pmBCN - MEM
2 stops39h 24mUnited Airlines
Deal found 10/16$461
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2612:37 pmMEM - MAD
1 stop13h 28mDelta
Tue 11/116:00 amMAD - MEM
2 stops24h 04mDelta
Deal found 10/15$462
This KLM deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/110:29 amMEM - MAD
1 stop15h 46mKLM
Mon 12/810:00 amMAD - MEM
1 stop14h 06mKLM
Deal found 10/15$479
This Finnair deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/510:48 amMEM - MAD
1 stop15h 07mMultiple Airlines
Mon 11/1012:55 amMAD - MEM
1 stop16h 48mMultiple Airlines
Deal found 10/15$481
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/252:50 pmMOB - BCN
2 stops15h 50mAmerican Airlines
Tue 12/912:30 pmBCN - MOB
2 stops17h 40mAmerican Airlines
Deal found 10/15$485
This Virgin Atlantic deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:39 amBTR - BCN
2 stops17h 21mVirgin Atlantic
Tue 11/1810:55 amBCN - BTR
1 stop14h 13mVirgin Atlantic
Deal found 10/14$488
This Air Canada deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:30 amMEM - BCN
2 stops19h 05mMultiple Airlines
Tue 11/256:50 amBCN - MEM
3 stops22h 09mMultiple Airlines
Deal found 10/16$492
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:55 pmMEM - MAD
2 stops30h 05mUnited Airlines
Mon 12/81:45 pmMAD - MEM
2 stops39h 14mUnited Airlines
Deal found 10/15$497
This KLM deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/17:12 pmMOB - BCN
2 stops14h 53mMultiple Airlines
Mon 12/810:55 amBCN - MOB
1 stop14h 37mMultiple Airlines
Deal found 10/16$503

Cheap flight deals from Mississippi to Spain

Keep the following information in mind while searching for Mississippi to Spain flight deals. Data was last updated October 16, 2025.

Round-trip from

$429
(Air France)

One-way from

$416
(Priceline)

Popular in

December

Cheapest in

February

Average price

$617
From Mississippi to Spain
Search Deals
One-way flight from Mississippi to Spain
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($341 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 12% potential price decrease ($119 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Mississippi to Spain that are best for you.

Fly from

Mississippi

Fly to

Spain

Route

Depart

Return

Price

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Wed 2/11

3:35 pm-9:15 am

1 stop10h 40m

Madrid Barajas

Thu 2/26

11:15 am-9:41 pm

1 stop17h 26m

$438

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Mon 2/9

3:35 pm-9:15 am

1 stop10h 40m

Madrid Barajas

Tue 2/24

11:15 am-8:51 pm

1 stop16h 36m

$438

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Mon 2/9

7:00 am-9:15 am

1 stop19h 15m

Madrid Barajas

Wed 2/25

11:15 am-2:28 pm

1 stop34h 13m

$438

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Tue 2/10

5:10 pm-9:15 am

1 stop33h 05m

Madrid Barajas

Wed 2/25

11:15 am-6:40 pm

1 stop14h 25m

$438

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Wed 2/11

12:00 pm-9:15 am

1 stop14h 15m

Madrid Barajas

Wed 2/25

11:15 am-9:08 am

1 stop28h 53m

$438

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Tue 2/10

5:10 pm-9:15 am

1 stop33h 05m

Madrid Barajas

Tue 2/24

11:15 am-12:43 pm

1 stop32h 28m

$438

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Mon 2/9

3:35 pm-9:15 am

1 stop10h 40m

Madrid Barajas

Thu 2/26

11:15 am-2:28 pm

1 stop34h 13m

$438

MemphisBarcelona

MEM - BCN

MEMBCN

Memphis

Tue 11/11

2:55 pm-1:10 pm

1 stop15h 15m

Barcelona-El Prat

Tue 11/25

1:35 pm-9:59 pm

2 stops39h 24m

$461

Baton RougeBarcelona

BTR - BCN

BTRBCN

Baton Rouge Ryan

Fri 11/14

7:39 am-8:00 am

2 stops17h 21m

Barcelona-El Prat

Tue 11/18

10:55 am-6:08 pm

1 stop14h 13m

$488

MemphisBarcelona

MEM - BCN

MEMBCN

Memphis

Tue 11/11

7:30 am-9:35 am

2 stops19h 05m

Barcelona-El Prat

Tue 11/25

6:50 am-9:59 pm

3 stops22h 09m

$492

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/14

Showing 1-10 of 32 results
1
2
3
4

Best time to book a flight from Mississippi to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Spain

What is the cheapest month to book a flight from Mississippi to Spain?

Currently, September is the cheapest month in which you can book a flight from Mississippi to Spain (average of $576). Flying from Mississippi to Spain in June is currently the most expensive (average of $1,277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to ES?

Find hourly flight availability from Mississippi to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

It’s optimal to fly from Mississippi to Spain in the morning. By choosing this option you can save up to 15% on the cost of your flight, compared to a flight in the evening.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Spain?

    For as low as $438, Delta can have you in Spain from Mississippi in 10h 40m. Airlines will cover a distance of 4535 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Mississippi to Spain that include hotel bookings?

    Yes. In addition to deals on Mississippi to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Spain.

  • Can I find deals for business class flights from Mississippi to Spain?

    Yes. Cheapflights offers flight deals from Mississippi to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Spain?

    Currently, September is the cheapest month in which you can book a flight from Mississippi to Spain (average of $576). Flying from Mississippi to Spain in June is currently the most expensive (average of $1,277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to Spain

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Heathrow flights
Newark to Heathrow flights
John F Kennedy Intl to Charles de Gaulle flights
Newark to Charles de Gaulle flights
John F Kennedy Intl to Leonardo da Vinci/Fiumicino flights
John F Kennedy Intl to Istanbul flights
Newark to Orly flights
John F Kennedy Intl to Gatwick flights
Boston to Heathrow flights
Newark to Leonardo da Vinci/Fiumicino flights
LaGuardia to Heathrow flights
Dulles Intl to Heathrow flights
John F Kennedy Intl to London City flights
Miami to Madrid flights
Los Angeles to Heathrow flights
Newark to Gatwick flights
Newark to Madrid flights
John F Kennedy Intl to Orly flights
John F Kennedy Intl to Lisbon flights
John F Kennedy Intl to Madrid flights
LaGuardia to Charles de Gaulle flights
John F Kennedy Intl to Barcelona-El Prat flights
Newark to Barcelona-El Prat flights
John F Kennedy Intl to Malpensa flights
San Francisco to Heathrow flights
Los Angeles to Charles de Gaulle flights
John F Kennedy Intl to Dublin flights
Boston to Charles de Gaulle flights
Newark to Dublin flights
John F Kennedy Intl to Stansted flights
Newark to Malpensa flights
O'Hare Intl to Heathrow flights
LaGuardia to Gatwick flights
Dulles Intl to Charles de Gaulle flights
John F Kennedy Intl to Luton flights
Newark to London City flights
Dallas/Fort Worth to Heathrow flights
Newark to Lisbon flights
O'Hare Intl to Charles de Gaulle flights
Baltimore to Heathrow flights
Dulles Intl to Madrid flights
John F Kennedy Intl to Amsterdam flights
Newark to Frankfurt flights
LaGuardia to Leonardo da Vinci/Fiumicino flights
Seattle to Heathrow flights
Newark to Amsterdam flights
John F Kennedy Intl to Athens flights
Newark to Athens flights
Newark to Stansted flights
John F Kennedy Intl to Beauvais-Tille flights

Top airline flying from Mississippi to Spain

Discover the top airline that operate flights from Mississippi to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$636Average$1,037FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.