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$368+ Cheap flights from Mississippi to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — MAD
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Mississippi to Spain

Cheapest flights from Mississippi to Spain
Explore the most affordable flight options available from Mississippi to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/910:32 amMEM - MAD
1 stop15h 43mDelta
Thu 2/2611:15 amMAD - MEM
1 stop30h 37mDelta
Deal found 12/2$438
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:00 amMEM - MAD
2 stops18h 00mDelta
Tue 3/311:15 amMAD - MEM
1 stop14h 11mDelta
Deal found 12/2$443
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amMEM - MAD
1 stop19h 00mDelta
Wed 12/176:00 amMAD - MEM
2 stops23h 39mDelta
Deal found 12/2$462
This Air Canada deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:39 amMEM - MAD
2 stops17h 21mAir Canada
Wed 3/41:35 pmMAD - MEM
2 stops39h 24mAir Canada
Deal found 12/2$472
This Virgin Atlantic deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:32 pmMEM - MAD
1 stop11h 43mVirgin Atlantic
Sun 3/111:15 amMAD - MEM
1 stop14h 11mVirgin Atlantic
Deal found 12/2$488
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/98:05 amMEM - MAD
1 stop18h 10mDelta
Mon 12/1510:00 amMAD - MEM
2 stops19h 07mDelta
Deal found 12/2$493
This FlightHub deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:39 amMEM - MAD
2 stops17h 21mAir Canada
Mon 3/21:35 pmMAD - MEM
2 stops39h 24mAir Canada
Deal found 12/2$498
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amMEM - MAD
1 stop20h 15mDelta
Wed 12/176:00 amMAD - MEM
2 stops23h 39mDelta
Deal found 12/2$512
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/109:00 amMEM - MAD
2 stops17h 15mUnited Airlines
Sun 12/1411:05 amMAD - MEM
2 stops17h 54mUnited Airlines
Deal found 12/2$519
This United Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/104:55 pmMOB - BCN
2 stops32h 25mUnited Airlines
Wed 12/1710:30 amBCN - MOB
1 stop16h 52mUnited Airlines
Deal found 12/1$525
This Expedia deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:05 pmMEM - MAD
1 stop30h 20mIberia
Mon 1/129:40 pmMAD - MEM
2 stops32h 11mIberia
Deal found 12/3$526
This Delta deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amMEM - MAD
1 stop20h 15mDelta
Sun 3/111:15 amMAD - MEM
1 stop19h 02mDelta
Deal found 12/2$538

Find flight deals from Mississippi to Spain

Keep the following information in mind while searching for Mississippi to Spain flight deals. Data was last updated December 4, 2025.

Round-trip from

$425
(oojo)

One-way from

$368
(oojo)

Popular in

December

Cheapest in

February

Average price

$2,154
From Mississippi to Spain
Search Deals
One-way flight from Mississippi to Spain
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($330 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 12% potential price decrease ($119 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Mississippi to Spain that are best for you.

Fly from

Mississippi

Fly to

Spain

Route

Depart

Return

Price

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Sun 1/11

10:27 am-5:45 am

1 stop12h 18m

Madrid Barajas

Tue 1/27

12:40 pm-8:32 pm

1 stop14h 52m

$429

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Mon 2/9

1:39 pm-9:15 am

1 stop12h 36m

Madrid Barajas

Wed 2/25

11:15 am-6:26 pm

1 stop14h 11m

$438

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Wed 3/4

12:36 pm-9:25 am

1 stop13h 49m

Madrid Barajas

Tue 3/10

12:00 pm-11:59 pm

1 stop17h 59m

$438

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Sun 2/8

5:22 pm-9:15 am

1 stop32h 53m

Madrid Barajas

Tue 2/24

11:15 am-6:26 pm

1 stop14h 11m

$438

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Mon 2/9

1:39 pm-9:15 am

1 stop12h 36m

Madrid Barajas

Thu 2/26

11:15 am-6:26 pm

1 stop14h 11m

$438

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Sun 2/8

5:22 pm-9:15 am

1 stop32h 53m

Madrid Barajas

Thu 2/26

11:15 am-6:26 pm

1 stop14h 11m

$438

MemphisBarcelona

MEM - BCN

MEMBCN

Memphis

Mon 3/9

7:05 am-7:40 am

1 stop18h 35m

Barcelona-El Prat

Thu 3/19

9:45 am-9:30 am

1 stop29h 45m

$439

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Tue 2/10

9:31 am-8:00 am

2 stops15h 29m

Madrid Barajas

Tue 2/24

10:00 am-7:36 pm

2 stops16h 36m

$443

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Mon 2/9

11:57 am-9:15 am

1 stop14h 18m

Madrid Barajas

Tue 2/24

10:00 am-7:36 pm

2 stops16h 36m

$443

MemphisMadrid

MEM - MAD

MEMMAD

Memphis

Tue 12/9

11:29 am-8:00 am

1 stop13h 31m

Madrid Barajas

Tue 12/16

10:00 am-9:55 am

2 stops30h 55m

$443

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Spain

What is the cheapest month to book a flight from Mississippi to Spain?

Currently, September is the cheapest month in which you can book a flight from Mississippi to Spain (average of $576). Flying from Mississippi to Spain in June is currently the most expensive (average of $1,277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to ES?

Find hourly flight availability from Mississippi to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

It’s optimal to fly from Mississippi to Spain in the morning. By choosing this option you can save up to 3% on the cost of your flight, compared to a flight in the evening.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Spain?

    For as low as $438, Delta can have you in Spain from Mississippi in 12h 36m. Airlines will cover a distance of 4535 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Mississippi to Spain that include hotel bookings?

    Yes. In addition to deals on Mississippi to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Spain.

  • Can I find deals for business class flights from Mississippi to Spain?

    Yes. Cheapflights offers flight deals from Mississippi to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Spain?

    Currently, September is the cheapest month in which you can book a flight from Mississippi to Spain (average of $576). Flying from Mississippi to Spain in June is currently the most expensive (average of $1,277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mississippi to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Mississippi to Spain

Discover the top airline that operate flights from Mississippi to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$636Average$1,037FlexibilityNo cancel feeOn-time71%

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