Spain

$285+ Cheap flights from Mississippi to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — MAD
Apr 4 — Apr 111
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Cheap flight deals from Mississippi to Spain

Cheapest flights from Mississippi to Spain
Explore the most affordable flight options available from Mississippi to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 5, 2026.

This Air Canada deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:22 pm
MEM
-
MAD
2 stops29h 28m
Air Canada
Wed 10/2112:45 pm
MAD
-
MEM
2 stops40h 08m
Air Canada
Deal found 3/1$538
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:30 am
MEM
-
MAD
2 stops17h 35m
United Airlines
Wed 10/2112:45 pm
MAD
-
MEM
3 stops39h 53m
United Airlines
Deal found 3/1$539
This Air Canada deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:22 pm
MEM
-
MAD
2 stops29h 28m
Air Canada
Tue 10/201:30 pm
MAD
-
MEM
2 stops39h 23m
Air Canada
Deal found 3/1$543
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:30 am
MEM
-
MAD
2 stops17h 35m
United Airlines
Tue 10/201:30 pm
MAD
-
MEM
2 stops32h 18m
United Airlines
Deal found 3/1$544
This Air Canada deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
MEM
-
MAD
2 stops19h 50m
Air Canada
Thu 10/221:30 pm
MAD
-
MEM
2 stops41h 00m
Air Canada
Deal found 3/1$547
This Air Canada deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:00 pm
MEM
-
MAD
2 stops32h 50m
Air Canada
Thu 10/221:30 pm
MAD
-
MEM
2 stops41h 00m
Air Canada
Deal found 3/1$548
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:05 am
MEM
-
MAD
1 stop17h 15m
Delta
Thu 10/222:35 pm
MAD
-
MEM
1 stop15h 27m
Delta
Deal found 3/1$550
This Expedia deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:17 pm
MEM
-
MAD
2 stops24h 48m
Iberia
Wed 10/213:55 pm
MAD
-
MEM
1 stop24h 52m
Iberia
Deal found 3/1$551
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:20 pm
MEM
-
MAD
2 stops16h 15m
Delta
Wed 10/212:35 pm
MAD
-
MEM
1 stop15h 27m
Delta
Deal found 3/1$554
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:22 pm
MOB
-
MAD
2 stops15h 33m
American Airlines
Tue 11/1011:00 am
MAD
-
MOB
2 stops19h 56m
American Airlines
Deal found 3/1$555
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:10 am
MEM
-
MAD
2 stops17h 10m
Delta
Wed 10/219:50 am
MAD
-
MEM
1 stop19h 58m
Delta
Deal found 3/1$555
This KLM deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 pm
GPT
-
MAD
1 stop32h 15m
Multiple Airlines
Tue 12/1510:00 am
MAD
-
GPT
2 stops19h 07m
Multiple Airlines
Deal found 3/5$593

Find flight deals from Mississippi to Spain

Keep the following information in mind while searching for Mississippi to Spain flight deals. Data was last updated March 5, 2026.

Round-trip from

$597
(Finnair)

One-way from

$285
(Kiwi.com)

Popular in

May

Cheapest in

February

Average price

$671
From Mississippi to Spain
One-way flight from Mississippi to Spain
Highest demand for flights based on searches. 54% potential increase in price ($1,172 potential increase over avg. RT price).
Cheapest flight prices on average. 35% potential price decrease ($262 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2026.
Use the filters below to find and compare flights from Mississippi to Spain that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

JacksonMadrid

JAN - MAD

JANMAD

Jackson-Evers Intl

Wed 4/15

6:05 pm-2:25 pm

1 stop13h 20m

Madrid Barajas

Wed 4/22

3:55 pm-9:03 am

1 stop24h 08m

$610

Baton RougeMadrid

BTR - MAD

BTRMAD

Baton Rouge Ryan

Wed 4/15

6:00 am-9:55 am

2 stops20h 55m

Madrid Barajas

Wed 4/22

2:35 pm-9:46 am

2 stops26h 11m

$615

Baton RougeMadrid

BTR - MAD

BTRMAD

Baton Rouge Ryan

Wed 4/15

5:40 am-9:05 am

1 stop20h 25m

Madrid Barajas

Wed 4/22

11:45 am-9:25 pm

2 stops16h 40m

$615

JacksonMadrid

JAN - MAD

JANMAD

Jackson-Evers Intl

Sun 4/19

6:53 am-5:30 am

1 stop15h 37m

Madrid Barajas

Tue 4/28

12:20 pm-11:10 pm

2 stops17h 50m

$615

JacksonMadrid

JAN - MAD

JANMAD

Jackson-Evers Intl

Sun 4/19

11:48 am-8:05 am

2 stops37h 17m

Madrid Barajas

Tue 4/28

10:50 am-9:59 pm

2 stops18h 09m

$626

JacksonMadrid

JAN - MAD

JANMAD

Jackson-Evers Intl

Wed 4/15

7:05 am-7:50 pm

2 stops29h 45m

Madrid Barajas

Wed 4/22

8:25 am-9:59 pm

2 stops20h 34m

$631

MobileMadrid

MOB - MAD

MOBMAD

Mobile

Thu 4/9

12:55 pm-8:05 am

1 stop12h 10m

Madrid Barajas

Tue 4/14

11:15 am-4:20 pm

2 stops36h 05m

$652

GulfportMadrid

GPT - MAD

GPTMAD

Gulfport Biloxi Regional

Thu 4/16

11:10 am-2:25 pm

1 stop20h 15m

Madrid Barajas

Thu 4/23

1:00 pm-10:51 pm

1 stop16h 51m

$660

GulfportMadrid

GPT - MAD

GPTMAD

Gulfport Biloxi Regional

Thu 4/16

6:00 am-5:35 am

2 stops16h 35m

Madrid Barajas

Thu 4/23

10:25 am-11:58 pm

1 stop20h 33m

$665

JacksonMadrid

JAN - MAD

JANMAD

Jackson-Evers Intl

Fri 4/17

7:05 am-9:00 am

2 stops18h 55m

Madrid Barajas

Fri 4/24

6:00 am-9:59 pm

2 stops22h 59m

$665

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/4

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Mississippi to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Spain

What is the cheapest month to book a flight from Mississippi to Spain?

Currently, September is the cheapest month in which you can book a flight from Mississippi to Spain (average of $569). Flying from Mississippi to Spain in June is currently the most expensive (average of $1,277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Mississippi to Spain?

    For as low as $615, Delta can have you in Spain from Mississippi in 20h 25m. Airlines will cover a distance of 4768 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Mississippi to Spain that include hotel bookings?

    Yes. In addition to deals on Mississippi to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Spain.

  • Can I find deals for business class flights from Mississippi to Spain?

    Yes. Cheapflights offers flight deals from Mississippi to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Spain?

    Currently, September is the cheapest month in which you can book a flight from Mississippi to Spain (average of $569). Flying from Mississippi to Spain in June is currently the most expensive (average of $1,277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to Spain

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Mississippi to Spain

Discover the top airline that operate flights from Mississippi to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$586Average$1,203FlexibilityNo cancel feeOn-time71%

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