$169+ Cheap flights from South Dakota to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — CHS
Oct 18 — Oct 251
Round-trip
1 adult, Economy
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Find cheap flights from South Dakota to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Dakota to South CarolinaExplore the most affordable flight options available from South Dakota to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
Explore the most affordable flight options available from South Dakota to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:53 pm -
1 stop8h 59m
Tue 10/277:00 am -
1 stop6h 13m
Deal found 9/15![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:22 am -
1 stop9h 07m
Tue 11/105:33 pm -
1 stop5h 04m
Deal found 9/16![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:09 pm -
1 stop7h 17m
Wed 12/163:29 pm -
1 stop7h 58m
Deal found 9/16![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:37 pm -
1 stop6h 11m
Sat 10/314:18 pm -
1 stop6h 25m
Deal found 9/17![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:45 am -
1 stop5h 41m
Wed 12/165:10 am -
2 stops10h 50m
Deal found 9/17![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:07 am -
1 stop8h 30m
Mon 11/237:30 am -
1 stop6h 03m
Deal found 9/16![American Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:00 pm -
1 stop5h 50m
Wed 10/147:15 pm -
1 stop5h 07m
Deal found 9/17![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:03 pm -
1 stop5h 12m
Tue 10/203:01 pm -
2 stops9h 10m
Deal found 9/16![United Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:00 am -
1 stop6h 41m
Mon 12/145:00 pm -
1 stop6h 42m
Deal found 9/14![United Airlines logo]()
$388
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop8h 11m
Sat 10/312:46 pm -
1 stop6h 10m
Deal found 9/13![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:50 am -
1 stop6h 26m
Sat 10/34:44 pm -
1 stop7h 27m
Deal found 9/14![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop6h 31m
Sat 10/37:00 am -
1 stop6h 16m
Deal found 9/14![American Airlines logo]()
$399
Best flights from South Dakota to South CarolinaDiscover carefully curated flight deals from South Dakota to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
Discover carefully curated flight deals from South Dakota to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/112:33 pm -
2 stops10h 23m
Tue 3/99:14 am -
2 stops12h 45m
Deal found 9/14![American Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:45 am -
1 stop5h 41m
Wed 12/166:19 am -
2 stops11h 34m
Deal found 9/18![Delta logo]()
$364
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/68:35 am -
2 stops12h 44m
Sun 1/104:45 pm -
1 stop7h 25m
Deal found 9/15![United Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:09 pm -
1 stop7h 17m
Wed 12/163:29 pm -
1 stop7h 58m
Deal found 9/16![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:37 pm -
1 stop6h 11m
Sat 10/319:50 am -
2 stops11h 29m
Deal found 9/17![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:00 pm -
1 stop5h 50m
Wed 10/147:15 pm -
1 stop5h 07m
Deal found 9/18![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/141:46 pm -
1 stop6h 45m
Wed 10/218:46 am -
1 stop8h 37m
Deal found 9/16![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop6h 31m
Sat 10/37:00 am -
1 stop6h 16m
Deal found 9/14![American Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:42 am -
1 stop5h 35m
Mon 12/145:30 am -
2 stops10h 30m
Deal found 9/17![Delta logo]()
$424
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:00 am -
1 stop6h 41m
Mon 12/145:00 pm -
1 stop6h 42m
Deal found 9/14![United Airlines logo]()
$388
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:06 pm -
2 stops9h 59m
Sat 10/32:06 pm -
2 stops11h 23m
Deal found 9/14![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop8h 11m
Sat 10/312:46 pm -
1 stop6h 10m
Deal found 9/13![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/111:09 pm -
1 stop7h 26m
Mon 12/142:45 pm -
1 stop8h 42m
Deal found 9/14![American Airlines logo]()
$429
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2510:58 am -
2 stops6h 45m
Sun 2/285:35 pm -
1 stop5h 37m
Deal found 9/16![Delta logo]()
$485
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:20 pm -
1 stop7h 09m
Mon 11/93:05 pm -
2 stops7h 32m
Deal found 9/17![United Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:50 am -
2 stops9h 58m
Sat 10/311:27 am -
1 stop7h 29m
Deal found 9/14![United Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:40 am -
1 stop5h 11m
Sat 1/94:45 pm -
1 stop6h 38m
Deal found 9/15![United Airlines logo]()
$411
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:38 pm -
1 stop5h 12m
Sun 10/257:04 am -
1 stop5h 41m
Deal found 9/15![Delta logo]()
$566
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:24 am -
1 stop7h 14m
Wed 11/47:26 am -
1 stop7h 13m
Deal found 9/13![American Airlines logo]()
$551
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:23 pm -
2 stops19h 14m
Wed 12/26:00 am -
2 stops10h 00m
Deal found 9/18![Delta logo]()
$568
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:37 pm -
1 stop6h 11m
Tue 10/62:10 pm -
2 stops10h 20m
Deal found 9/17![United Airlines logo]()
$434
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
2 stops8h 41m
Mon 11/235:00 am -
2 stops8h 33m
Deal found 9/17![American Airlines logo]()
$579
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:40 am -
1 stop6h 57m
Tue 1/124:15 pm -
1 stop7h 41m
Deal found 9/16![United Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:36 pm -
2 stops15h 31m
Wed 12/26:00 am -
2 stops10h 00m
Deal found 9/18![Delta logo]()
$623
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:22 am -
1 stop9h 07m
Tue 11/1012:21 pm -
2 stops10h 16m
Deal found 9/16![United Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/44:00 pm -
1 stop5h 22m
Sun 3/147:45 am -
1 stop5h 27m
Deal found 9/18![Delta logo]()
$625
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:00 am -
1 stop5h 51m
Sat 1/94:45 pm -
1 stop7h 25m
Deal found 9/15![United Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
1 stop6h 31m
Mon 10/51:52 pm -
1 stop8h 21m
Deal found 9/16![American Airlines logo]()
$668
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:23 pm -
2 stops19h 14m
Fri 12/411:26 am -
2 stops25h 00m
Deal found 9/18![Delta logo]()
$652
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:00 am -
1 stop7h 37m
Tue 1/124:50 pm -
1 stop7h 20m
Deal found 9/13![United Airlines logo]()
$449
Last-minute flights from South Dakota to South CarolinaDiscover last-minute flight deals from South Dakota to South Carolina. Data last updated September 18, 2026 and is based on user searches.
Discover last-minute flight deals from South Dakota to South Carolina. Data last updated September 18, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop8h 11m
Sat 10/312:46 pm -
1 stop6h 10m
Deal found 9/13![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:50 am -
1 stop6h 26m
Sat 10/34:44 pm -
1 stop7h 27m
Deal found 9/14![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop6h 31m
Sat 10/37:00 am -
1 stop6h 16m
Deal found 9/14![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:06 pm -
1 stop6h 55m
Sat 10/37:30 am -
1 stop5h 06m
Deal found 9/14![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:06 pm -
1 stop6h 05m
Sat 10/36:44 am -
1 stop6h 32m
Deal found 9/14![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
2 stops8h 40m
Sat 10/312:57 pm -
1 stop8h 48m
Deal found 9/13![American Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/105:00 pm -
1 stop5h 50m
Wed 10/147:15 pm -
1 stop5h 07m
Deal found 9/17![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:03 pm -
1 stop5h 12m
Tue 10/203:01 pm -
2 stops9h 10m
Deal found 9/16![United Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:53 pm -
1 stop8h 59m
Tue 10/277:00 am -
1 stop6h 13m
Deal found 9/15![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:37 pm -
1 stop6h 11m
Sat 10/314:18 pm -
1 stop6h 25m
Deal found 9/17![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:22 am -
1 stop9h 07m
Tue 11/105:33 pm -
1 stop5h 04m
Deal found 9/16![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:20 pm -
1 stop7h 09m
Mon 11/93:05 pm -
2 stops7h 32m
Deal found 9/16![United Airlines logo]()
$404
One-way flights from South Dakota to South CarolinaSearch for one-way flight options from South Dakota to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
Search for one-way flight options from South Dakota to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:38 pm -
1 stop14h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:34 pm -
1 stop12h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1411:07 am -
3 stops26h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:06 pm -
2 stops20h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/139:48 pm -
2 stops16h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:42 pm -
3 stops18h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:20 am -
1 stop7h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/231:13 pm -
1 stop8h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:53 pm -
1 stop5h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:08 pm -
1 stop8h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/11:08 pm -
2 stops9h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
2 stops7h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$324
Find flight deals from South Dakota to South Carolina
Keep the following information in mind while searching for South Dakota to South Carolina flight deals. Data was last updated September 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $349 (American Airlines) |
One-way from | $169 (Kiwi.com) |
Popular in | November |
Cheapest in | August |
Average price | $500 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Dakota to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
Use the filters below to find and compare flights from South Dakota to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Mon 11/23
6:38 pm-9:55 am
1 stop14h 17m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$169
Sioux FallsMyrtle Beach
FSD Sioux Falls Joe Foss Field - MYR Myrtle Beach Intl
FSDMYR
Sioux Falls Joe Foss Field
Sun 11/1
7:34 pm-8:45 am
1 stop12h 11m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$170
Sioux FallsSavannah
FSD Sioux Falls Joe Foss Field - SAV Savannah/Hilton Head
FSDSAV
Sioux Falls Joe Foss Field
Sun 10/18
6:42 pm-2:32 pm
3 stops18h 50m
Savannah/Hilton Head
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$277
Rapid CityCharlotte
RAP Rapid City - CLT Charlotte Douglas
RAPCLT
Rapid City
Sun 11/15
2:23 pm-11:27 pm
1 stop7h 04m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$284
Quickest round-trip
Rapid CityCharlotte
RAP Rapid City - CLT Charlotte Douglas
RAPCLT
Rapid City
Sat 3/13
4:00 pm-11:22 pm
1 stop5h 22m
Charlotte Douglas
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$284
Sioux FallsSavannah
FSD Sioux Falls Joe Foss Field - SAV Savannah/Hilton Head
FSDSAV
Sioux Falls Joe Foss Field
Sun 10/18
6:20 am-2:23 pm
1 stop7h 03m
Savannah/Hilton Head
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$319
Sioux FallsCharlotte
FSD Sioux Falls Joe Foss Field - CLT Charlotte Douglas
FSDCLT
Sioux Falls Joe Foss Field
Tue 11/3
1:20 pm-9:29 pm
1 stop7h 09m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$319
Sioux FallsCharlotte
FSD Sioux Falls Joe Foss Field - CLT Charlotte Douglas
FSDCLT
Sioux Falls Joe Foss Field
Thu 10/22
12:53 pm-7:38 pm
1 stop5h 45m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$319
Sioux FallsCharlotte
FSD Sioux Falls Joe Foss Field - CLT Charlotte Douglas
FSDCLT
Sioux Falls Joe Foss Field
Wed 10/28
12:53 pm-9:41 pm
1 stop7h 48m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$319
Sioux FallsCharleston
FSD Sioux Falls Joe Foss Field - CHS Charleston
FSDCHS
Sioux Falls Joe Foss Field
Tue 11/10
5:25 am-12:52 pm
1 stop6h 27m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$319
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Dakota to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from South Dakota with our price prediction graph.
FSD-MYR
RAP-CHS
RAP-SAV
FSD-CLT
FSD-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Dakota to South Carolina
USSD-USSC
FSD-MYR
RAP-CHS
RAP-SAV
FSD-CLT
What is the cheapest month to book a flight from South Dakota to South Carolina?
Currently, August is the cheapest month in which you can book a flight from South Dakota to South Carolina (average of $349). Flying from South Dakota to South Carolina in October is currently the most expensive (average of $629). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Dakota to South Carolina?
Airfare is below average for this route at the moment.
South Dakota to South Carolina flights typically cost between $378 and $503 in March.The cheapest round-trip price found within the last 5 days was $360 on American Airlines (Mar 3-Mar 8).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 18, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from South Dakota to South Carolina. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from South Dakota to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Dakota to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Dakota to South Carolina by cabin class
Find flights from South Dakota to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Dakota and South Carolina flights
Browse other South Dakota and South Carolina flight options. Last updated on September 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to South Dakota after your stay in South Carolina
South Dakota to South Carolina flights
Consider these flights traveling from South Dakota to South Carolina.
Top 3 airlines flying from South Dakota to South Carolina
Discover the top 3 airlines that operate flights from South Dakota to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$258 | Average$409 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$264 | Average$480 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$308 | Average$542 | FlexibilityNo cancel fee | On-time71% |