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South Carolina

$167+ Cheap flights from South Dakota to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — CHS
Apr 19 — Apr 261
Sun 4/19
Sun 4/26
1 adult, Economy
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Cheap flight deals from South Dakota to South Carolina

Cheapest flights from South Dakota to South Carolina
Explore the most affordable flight options available from South Dakota to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 20, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:11 pm
FSD
-
CLT
1 stop13h 59m
Multiple Airlines
Mon 5/48:56 am
CLT
-
FSD
1 stop9h 25m
Multiple Airlines
Deal found 3/18$252
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:11 pm
FSD
-
CLT
1 stop13h 59m
Multiple Airlines
Mon 4/278:56 am
CLT
-
FSD
1 stop9h 25m
Multiple Airlines
Deal found 3/19$259
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:11 pm
FSD
-
CLT
1 stop18h 43m
Multiple Airlines
Wed 5/207:58 pm
CLT
-
FSD
1 stop23h 14m
Multiple Airlines
Deal found 3/17$260
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:11 pm
FSD
-
CLT
1 stop13h 59m
Multiple Airlines
Mon 4/278:56 am
CLT
-
FSD
1 stop9h 25m
Multiple Airlines
Deal found 3/18$264
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:11 pm
FSD
-
CLT
1 stop16h 54m
Multiple Airlines
Wed 5/207:58 pm
CLT
-
FSD
1 stop23h 14m
Multiple Airlines
Deal found 3/17$266
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:11 pm
FSD
-
MYR
1 stop25h 44m
Multiple Airlines
Sun 5/1011:52 am
MYR
-
FSD
1 stop30h 29m
Multiple Airlines
Deal found 3/15$283
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:39 am
FSD
-
MYR
1 stop5h 38m
United Airlines
Wed 4/223:15 pm
MYR
-
FSD
1 stop7h 39m
United Airlines
Deal found 3/17$291
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/198:19 am
FSD
-
CLT
1 stop4h 13m
Delta
Wed 5/206:16 am
CLT
-
FSD
1 stop7h 33m
Delta
Deal found 3/17$291
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:11 pm
FSD
-
CLT
1 stop16h 54m
Multiple Airlines
Mon 5/257:58 pm
CLT
-
FSD
1 stop17h 33m
Multiple Airlines
Deal found 3/17$295
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:39 am
FSD
-
MYR
2 stops8h 30m
United Airlines
Sat 5/23:14 pm
MYR
-
FSD
1 stop7h 38m
United Airlines
Deal found 3/18$296
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:35 pm
FSD
-
CLT
2 stops17h 43m
Multiple Airlines
Mon 5/48:56 am
CLT
-
FSD
1 stop9h 25m
Multiple Airlines
Deal found 3/19$300
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/59:55 am
FSD
-
CLT
1 stop13h 41m
Multiple Airlines
Wed 4/87:45 pm
CLT
-
FSD
2 stops47h 03m
Multiple Airlines
Deal found 3/17$301

Find flight deals from South Dakota to South Carolina

Keep the following information in mind while searching for South Dakota to South Carolina flight deals. Data was last updated March 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$252
(Kiwi.com)

One-way from

$167
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$354
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Myrtle Beach Intl flights.
Search Deals
From South Dakota to South Carolina
Search Deals
One-way flight from South Dakota to South Carolina
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($0 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Dakota to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
Use the filters below to find and compare flights from South Dakota to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Sat 4/18

7:39 am-2:17 pm

1 stop5h 38m

Myrtle Beach Intl

Wed 4/22

3:15 pm-9:54 pm

1 stop7h 39m

$291

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Sat 4/25

6:10 am-5:09 pm

2 stops9h 59m

Myrtle Beach Intl

Sat 5/2

3:14 pm-9:52 pm

1 stop7h 38m

$316

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Fri 4/17

6:11 pm-11:29 pm

1 stop28h 18m

Myrtle Beach Intl

Mon 4/20

9:58 am-5:21 pm

1 stop8h 23m

$323

Sioux FallsHilton Head Island

FSD - HHH

FSDHHH

Sioux Falls Joe Foss Field

Sat 4/18

6:10 am-2:16 pm

1 stop7h 06m

Hilton Head Island

Wed 4/22

3:05 pm-9:54 pm

1 stop7h 49m

$323

Rapid CitySavannah

RAP - SAV

RAPSAV

Rapid City

Sat 4/18

11:53 am-11:58 pm

2 stops10h 05m

Savannah/Hilton Head

Sat 4/25

5:40 am-11:23 am

1 stop7h 43m

$334

Sioux FallsCharlotte

FSD - CLT

FSDCLT

Sioux Falls Joe Foss Field

Fri 5/8

8:19 am-1:32 pm

1 stop4h 13m

Charlotte Douglas

Fri 8/21

6:20 am-12:28 pm

1 stop7h 08m

$339

Sioux FallsCharlotte

FSD - CLT

FSDCLT

Sioux Falls Joe Foss Field

Thu 6/18

8:15 am-2:06 pm

1 stop4h 51m

Charlotte Douglas

Sun 6/21

6:20 am-12:28 pm

1 stop7h 08m

$339

Sioux FallsSavannah

FSD - SAV

FSDSAV

Sioux Falls Joe Foss Field

Sat 5/2

3:15 pm-9:13 pm

1 stop4h 58m

Savannah/Hilton Head

Sat 5/9

8:08 am-2:38 pm

1 stop7h 30m

$339

Sioux FallsMyrtle Beach

FSD - MYR

FSDMYR

Sioux Falls Joe Foss Field

Tue 9/15

7:40 am-2:15 pm

1 stop5h 35m

Myrtle Beach Intl

Sat 9/19

3:21 pm-9:52 pm

1 stop7h 31m

$339

Sioux FallsSavannah

FSD - SAV

FSDSAV

Sioux Falls Joe Foss Field

Sat 5/2

6:47 am-2:30 pm

1 stop6h 43m

Savannah/Hilton Head

Sat 5/9

5:00 am-2:47 pm

2 stops10h 47m

$344

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/17

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from South Dakota to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to South Carolina

What is the cheapest month to book a flight from South Dakota to South Carolina?

Currently, September is the cheapest month in which you can book a flight from South Dakota to South Carolina (average of $174). Flying from South Dakota to South Carolina in February is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SD to SC?

Find hourly flight availability from South Dakota to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 20, 2026.

It’s typically best to fly out from South Dakota to South Carolina in the evening. Doing so could potentially save you 60% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from South Dakota to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from South Dakota to South Carolina. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their South Dakota to South Carolina flight should consider departing on Sunday mornings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from South Dakota to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 20, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from South Dakota to South Carolina. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,302 reviews

Entertainment

7.8

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,302 reviews
Delta
7.9
Good
8,302 reviews

Entertainment

7.8

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,450 reviews
Delta
7.9
Good
8,302 reviews

Entertainment

7.8

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,480 reviews
Delta
7.9
Good
8,302 reviews

Entertainment

7.8

Boarding

8.1

Crew

8.5

Food

7.2

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from South Dakota to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Dakota to South Carolina?

    For as low as $339, United Airlines can have you in South Carolina from South Dakota in 4h 13m. South Dakota and South Carolina are separated by a distance of 1019 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Dakota to South Carolina that include hotel bookings?

    Yes. In addition to deals on South Dakota to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to South Carolina.

  • Can I find deals for business class flights from South Dakota to South Carolina?

    Yes. Cheapflights offers flight deals from South Dakota to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from South Dakota to South Carolina (average of $174). Flying from South Dakota to South Carolina in February is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from South Dakota to South Carolina

Discover the top 3 airlines that operate flights from South Dakota to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$160Average$401FlexibilityNo cancel feeOn-time69%
DeltaCheapest$250Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$467FlexibilityNo cancel feeOn-time71%

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