South Carolina

$66+ Cheap flights from San Antonio (SAT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — CHS
Mar 15 — Mar 221
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Cheap flight deals from San Antonio to South Carolina

Cheapest flights from San Antonio to South Carolina
Explore the most affordable flight options available from San Antonio to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:00 am
SAT
-
CLT
1 stop25h 03m
Multiple Airlines
Sun 3/85:49 pm
CLT
-
SAT
1 stop20h 34m
Multiple Airlines
Deal found 2/11$161
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/25:08 pm
SAT
-
CLT
2 stops29h 48m
Multiple Airlines
Wed 3/42:46 pm
CLT
-
SAT
1 stop23h 26m
Multiple Airlines
Deal found 2/10$167
This Expedia deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:00 am
SAT
-
CLT
1 stop9h 54m
Spirit Airlines
Sat 2/285:49 pm
CLT
-
SAT
1 stop7h 10m
Spirit Airlines
Deal found 2/11$170
This Mytrip deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/510:26 am
SAT
-
CLT
1 stop12h 30m
Spirit Airlines
Mon 3/95:49 pm
CLT
-
SAT
1 stop7h 10m
Spirit Airlines
Deal found 2/10$171
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/232:40 pm
SAT
-
CLT
1 stop16h 23m
Frontier
Mon 3/309:28 pm
CLT
-
SAT
1 stop16h 55m
Frontier
Deal found 2/11$174
This Cheapflightsfares deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:00 am
SAT
-
CLT
1 stop9h 54m
Spirit Airlines
Tue 3/105:49 pm
CLT
-
SAT
1 stop7h 10m
Spirit Airlines
Deal found 2/10$176
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:00 am
SAT
-
CLT
1 stop27h 17m
Multiple Airlines
Thu 3/510:46 pm
CLT
-
SAT
1 stop15h 52m
Multiple Airlines
Deal found 2/12$177
This CheapOair deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:00 am
SAT
-
CLT
1 stop11h 23m
Spirit Airlines
Thu 5/79:24 pm
CLT
-
SAT
1 stop12h 47m
Spirit Airlines
Deal found 2/11$185
This CheapOair deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/81:22 pm
SAT
-
CLT
1 stop5h 26m
Multiple Airlines
Sun 4/127:49 pm
CLT
-
SAT
1 stop29h 30m
Multiple Airlines
Deal found 2/11$188
This Cheapflightsfares deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:00 am
SAT
-
CLT
1 stop9h 54m
Spirit Airlines
Tue 3/35:49 pm
CLT
-
SAT
1 stop7h 10m
Spirit Airlines
Deal found 2/11$189
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:14 pm
SAT
-
CLT
1 stop26h 40m
Multiple Airlines
Thu 5/79:24 pm
CLT
-
SAT
1 stop12h 47m
Multiple Airlines
Deal found 2/10$190
This CheapOair deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/810:22 am
SAT
-
MYR
1 stop6h 11m
Spirit Airlines
Sun 4/126:28 pm
MYR
-
SAT
1 stop15h 59m
Spirit Airlines
Deal found 2/11$208

Find flight deals from San Antonio to South Carolina

Keep the following information in mind while searching for San Antonio to South Carolina flight deals. Data was last updated February 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$161
(Kiwi.com)

One-way from

$66
(Kiwi.com)

Popular in

February

Cheapest in

April

Average price

$538
Provider with most accurate pricing for San Antonio-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for San Antonio-Myrtle Beach Intl flights.
From San Antonio to South Carolina
One-way flight from San Antonio to South Carolina
Highest demand for flights based on searches. 6% potential increase in price ($27 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from San Antonio to South Carolina that are best for you.

Fly from

San Antonio

Fly to

South Carolina

Route

Depart

Return

Price

San AntonioCharlotte

SAT - CLT

SATCLT

San Antonio

Mon 3/23

2:40 pm-8:03 am

1 stop16h 23m

Charlotte Douglas

Mon 3/30

9:28 pm-1:23 pm

1 stop16h 55m

$174

San AntonioCharlotte

SAT - CLT

SATCLT

San Antonio

Tue 3/3

6:00 am-4:54 pm

1 stop9h 54m

Charlotte Douglas

Tue 3/10

5:49 pm-11:59 pm

1 stop7h 10m

$176

San AntonioCharlotte

SAT - CLT

SATCLT

San Antonio

Mon 3/2

6:00 am-10:17 am

1 stop27h 17m

Charlotte Douglas

Thu 3/5

10:46 pm-1:38 pm

1 stop15h 52m

$177

San AntonioCharlotte

SAT - CLT

SATCLT

San Antonio

Wed 5/6

6:00 am-6:22 pm

1 stop11h 22m

Charlotte Douglas

Thu 5/7

3:30 pm-9:24 am

1 stop18h 54m

$188

San AntonioCharlotte

SAT - CLT

SATCLT

San Antonio

Wed 2/25

6:00 am-4:54 pm

1 stop9h 54m

Charlotte Douglas

Tue 3/3

5:49 pm-11:59 pm

1 stop7h 10m

$189

San AntonioCharlotte

SAT - CLT

SATCLT

San Antonio

Thu 3/12

2:13 pm-7:58 am

1 stop16h 45m

Charlotte Douglas

Thu 3/19

9:00 pm-9:27 am

1 stop13h 27m

$191

San AntonioCharlotte

SAT - CLT

SATCLT

San Antonio

Thu 3/5

10:26 am-6:18 pm

1 stop6h 52m

Charlotte Douglas

Mon 3/9

7:13 pm-9:30 am

1 stop15h 17m

$191

San AntonioCharlotte

SAT - CLT

SATCLT

San Antonio

Mon 4/13

10:22 am-12:07 pm

1 stop24h 45m

Charlotte Douglas

Mon 4/20

7:17 pm-10:18 pm

1 stop28h 01m

$194

San AntonioCharlotte

SAT - CLT

SATCLT

San Antonio

Mon 4/13

6:25 am-12:05 pm

1 stop4h 40m

Charlotte Douglas

Thu 4/16

7:00 pm-12:30 am

1 stop6h 30m

$197

San AntonioCharlotte

SAT - CLT

SATCLT

San Antonio

Sat 5/16

10:26 am-10:33 pm

1 stop11h 07m

Charlotte Douglas

Sat 5/23

11:12 am-10:18 pm

1 stop12h 06m

$199

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Showing 1-10 of 60 results
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Best time to book a flight from San Antonio to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to South Carolina

What is the cheapest month to book a flight from San Antonio to South Carolina?

Currently, September is the cheapest month in which you can book a flight from San Antonio to South Carolina (average of $130). Flying from San Antonio to South Carolina in March is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to SC?

Find hourly flight availability from San Antonio to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 13, 2026.

It’s typically best to fly out from San Antonio to South Carolina in the evening. Doing so could potentially save you 66% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from San Antonio to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from San Antonio to South Carolina. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their San Antonio to South Carolina flight should consider departing on Wednesday evenings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 13, 2026.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from San Antonio to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from San Antonio to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from San Antonio to South Carolina?

    Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to South Carolina from San Antonio.

  • How long is the flight from San Antonio to South Carolina?

    There are many flights that can get you from San Antonio to South Carolina in 6h 41m. Fly via Frontier, Spirit Airlines, or American Airlines to get the fastest option. Airlines will cover a distance of 1068 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from San Antonio to South Carolina one-way?

    The cheapest airline one-way is Volaris, with whom users have recently found tickets for as low as $39. However, be on the lookout for offers from Viva and Aeromexico, as they are both options that can get you from San Antonio to South Carolina for a low price.

  • What are the most popular routes from San Antonio to South Carolina?

  • Can I find deals for flights from San Antonio to South Carolina that include hotel bookings?

    Yes. In addition to deals on San Antonio to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to South Carolina.

  • Can I find deals for business class flights from San Antonio to South Carolina?

    Yes. Cheapflights offers flight deals from San Antonio to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from San Antonio to South Carolina (average of $130). Flying from San Antonio to South Carolina in March is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for San Antonio to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from San Antonio to South Carolina

Discover the top 4 airlines that operate flights from San Antonio to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$148Average$390FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$258Average$399FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$310Average$447FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$328Average$419FlexibilityNo cancel feeOn-time69%

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