$140+ Cheap flights from South Carolina to San Antonio (SAT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/27. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SAT
Oct 29 — Nov 51
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to San Antonio
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Cheapest flights from South Carolina to San AntonioExplore the most affordable flight options available from South Carolina to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
Explore the most affordable flight options available from South Carolina to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2026.
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:25 pm -
1 stop6h 32m
Sat 10/315:00 am -
1 stop7h 28m
Deal found 9/28![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:20 am -
1 stop6h 46m
Sat 10/245:30 am -
2 stops7h 36m
Deal found 9/24![United Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:20 am -
2 stops10h 18m
Sat 11/79:35 am -
1 stop4h 39m
Deal found 9/24![United Airlines logo]()
$327
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:40 am -
1 stop5h 03m
Fri 10/305:30 am -
1 stop4h 30m
Deal found 9/28![Delta logo]()
$334
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:41 pm -
1 stop7h 19m
Mon 11/21:23 pm -
1 stop6h 41m
Deal found 9/27![American Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:12 pm -
1 stop5h 14m
Fri 10/3012:24 pm -
2 stops9h 36m
Deal found 9/28![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:47 pm -
1 stop5h 01m
Sat 12/57:27 am -
1 stop4h 55m
Deal found 9/25![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:30 am -
1 stop7h 46m
Thu 10/292:20 pm -
1 stop6h 39m
Deal found 9/28![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:04 pm -
1 stop4h 52m
Mon 10/266:00 pm -
1 stop5h 05m
Deal found 9/28![American Airlines logo]()
$340
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:25 pm -
1 stop7h 00m
Sat 12/56:05 am -
2 stops10h 15m
Deal found 9/25![Southwest logo]()
$344
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:11 pm -
1 stop7h 15m
Wed 11/45:30 am -
1 stop4h 18m
Deal found 9/29![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:50 pm -
1 stop5h 10m
Wed 12/26:45 am -
2 stops6h 25m
Deal found 9/27![Southwest logo]()
$351
Best flights from South Carolina to San AntonioDiscover carefully curated flight deals from South Carolina to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
Discover carefully curated flight deals from South Carolina to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2026.
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:40 am -
1 stop5h 08m
Thu 12/105:16 am -
1 stop4h 57m
Deal found 9/24![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:20 am -
2 stops10h 18m
Sat 11/79:35 am -
1 stop4h 39m
Deal found 9/24![United Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:25 pm -
1 stop7h 00m
Sat 12/56:05 am -
2 stops10h 15m
Deal found 9/25![Southwest logo]()
$344
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/182:40 pm -
1 stop6h 03m
Sat 11/215:49 pm -
1 stop5h 06m
Deal found 9/28![American Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/16:00 am -
2 stops10h 40m
Mon 2/84:15 pm -
1 stop4h 31m
Deal found 9/27![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:43 pm -
1 stop7h 50m
Mon 11/25:30 am -
1 stop6h 43m
Deal found 9/28![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:05 am -
2 stops7h 10m
Thu 12/103:30 pm -
1 stop4h 15m
Deal found 9/24![Southwest logo]()
$351
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:29 am -
1 stop6h 57m
Fri 10/3012:24 pm -
1 stop5h 44m
Deal found 9/26![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:11 pm -
1 stop7h 15m
Wed 11/45:30 am -
1 stop4h 18m
Deal found 9/24![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:00 pm -
1 stop7h 20m
Thu 10/2911:20 am -
1 stop9h 30m
Deal found 9/28![Southwest logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:26 am -
1 stop5h 30m
Wed 11/45:00 am -
2 stops7h 14m
Deal found 9/24![American Airlines logo]()
$413
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/12:40 pm -
2 stops9h 10m
Sun 2/76:38 am -
1 stop6h 13m
Deal found 9/27![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:41 pm -
1 stop6h 00m
Thu 12/315:07 am -
1 stop4h 41m
Deal found 9/24![Delta logo]()
$358
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:45 am -
1 stop5h 55m
Mon 11/212:25 pm -
2 stops7h 30m
Deal found 9/27![Southwest logo]()
$381
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:40 am -
1 stop5h 02m
Sun 10/187:50 am -
1 stop4h 10m
Deal found 9/27![Delta logo]()
$368
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:38 pm -
1 stop6h 12m
Sat 10/246:35 am -
2 stops11h 28m
Deal found 9/28![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/163:25 pm -
2 stops8h 40m
Sat 12/197:25 am -
1 stop10h 40m
Deal found 9/26![Southwest logo]()
$406
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:43 pm -
1 stop5h 05m
Sun 11/15:30 am -
1 stop6h 43m
Deal found 9/28![Delta logo]()
$388
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:26 am -
2 stops9h 44m
Sat 10/3111:45 am -
2 stops8h 13m
Deal found 9/24![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:30 am -
1 stop5h 38m
Tue 11/245:00 am -
2 stops6h 17m
Deal found 9/28![American Airlines logo]()
$533
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:35 am -
2 stops6h 40m
Tue 11/245:40 pm -
1 stop5h 35m
Deal found 9/28![Southwest logo]()
$418
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:05 pm -
1 stop6h 28m
Sun 11/17:50 am -
1 stop4h 23m
Deal found 9/28![Delta logo]()
$388
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:55 pm -
1 stop5h 05m
Sun 11/155:25 am -
2 stops6h 35m
Deal found 9/24![Southwest logo]()
$431
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/15:10 pm -
1 stop6h 17m
Sun 2/78:00 am -
1 stop5h 10m
Deal found 9/27![Delta logo]()
$397
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/211:28 am -
2 stops12h 31m
Wed 2/37:00 am -
1 stop8h 49m
Deal found 9/24![United Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:09 am -
1 stop6h 52m
Tue 10/139:09 am -
1 stop4h 45m
Deal found 9/24![American Airlines logo]()
$606
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/13:15 pm -
2 stops8h 55m
Sun 2/77:30 am -
2 stops8h 00m
Deal found 9/27![Southwest logo]()
$435
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:30 am -
1 stop5h 18m
Fri 11/65:30 am -
1 stop17h 29m
Deal found 9/28![Delta logo]()
$417
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:15 am -
1 stop6h 51m
Sat 10/245:30 am -
2 stops10h 27m
Deal found 9/25![United Airlines logo]()
$464
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:55 pm -
1 stop5h 05m
Fri 11/201:10 pm -
2 stops6h 50m
Deal found 9/28![Southwest logo]()
$447
Last-minute flights from South Carolina to San AntonioDiscover last-minute flight deals from South Carolina to San Antonio. Data last updated September 29, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to San Antonio. Data last updated September 29, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:20 am -
1 stop6h 46m
Sat 10/245:30 am -
2 stops7h 36m
Deal found 9/24![United Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:04 pm -
1 stop4h 52m
Mon 10/266:00 pm -
1 stop5h 05m
Deal found 9/28![American Airlines logo]()
$340
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:29 am -
2 stops12h 02m
Fri 10/3012:24 pm -
1 stop5h 44m
Deal found 9/26![United Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:00 pm -
1 stop7h 20m
Thu 10/2911:20 am -
1 stop9h 30m
Deal found 9/28![Southwest logo]()
$362
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:25 pm -
1 stop6h 32m
Sat 10/315:00 am -
1 stop7h 28m
Deal found 9/28![American Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:40 am -
1 stop5h 03m
Fri 10/305:30 am -
1 stop4h 30m
Deal found 9/28![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:12 pm -
1 stop5h 14m
Fri 10/3012:24 pm -
2 stops9h 36m
Deal found 9/28![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:30 am -
1 stop7h 46m
Thu 10/292:20 pm -
1 stop6h 39m
Deal found 9/28![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:00 pm -
1 stop6h 48m
Thu 10/295:30 am -
1 stop6h 30m
Deal found 9/28![Delta logo]()
$358
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:21 pm -
2 stops10h 05m
Sat 10/3111:45 am -
2 stops8h 17m
Deal found 9/28![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:41 pm -
1 stop7h 19m
Mon 11/21:23 pm -
1 stop6h 41m
Deal found 9/27![American Airlines logo]()
$335
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:11 pm -
1 stop7h 15m
Wed 11/45:30 am -
1 stop4h 18m
Deal found 9/24![Delta logo]()
$349
One-way flights from South Carolina to San AntonioSearch for one-way flight options from South Carolina to San Antonio. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
Search for one-way flight options from South Carolina to San Antonio. Find affordable one-way fares based on user searches. Data last updated September 29, 2026.
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:40 pm -
1 stop5h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Southwest logo]()
$140
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:51 pm -
2 stops9h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![United Airlines logo]()
$145
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:58 pm -
1 stop6h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Delta logo]()
$170
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:20 pm -
1 stop6h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Delta logo]()
$170
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:00 pm -
2 stops8h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![United Airlines logo]()
$175
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:45 pm -
1 stop5h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![American Airlines logo]()
$178
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:20 am -
2 stops10h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![United Airlines logo]()
$188
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:59 pm -
1 stop6h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Delta logo]()
$188
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2311:27 am -
2 stops12h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![United Airlines logo]()
$189
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:20 am -
2 stops10h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![United Airlines logo]()
$190
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:40 pm -
1 stop5h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Southwest logo]()
$195
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:58 pm -
1 stop6h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![United Airlines logo]()
$195
Find flight deals from South Carolina to San Antonio
Keep the following information in mind while searching for South Carolina to San Antonio flight deals. Data was last updated September 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $279 (American Airlines) |
One-way from | $140 (Southwest) |
Popular in | January |
Cheapest in | February |
Average price | $410 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
Use the filters below to find and compare flights from South Carolina to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSan Antonio
GSP Greenville - SAT San Antonio
GSPSAT
Greenville
Tue 10/27
5:00 pm-9:48 pm
1 stop5h 48m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$140
GreenvilleSan Antonio
GSP Greenville - SAT San Antonio
GSPSAT
Greenville
Thu 10/22
8:40 pm-12:45 am
1 stop5h 05m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$140
GreenvilleSan Antonio
GSP Greenville - SAT San Antonio
GSPSAT
Greenville
Sat 10/17
6:20 am-12:06 pm
1 stop6h 46m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$140
GreenvilleSan Antonio
GSP Greenville - SAT San Antonio
GSPSAT
Greenville
Mon 10/26
7:14 pm-12:33 am
1 stop6h 19m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$140
GreenvilleSan Antonio
GSP Greenville - SAT San Antonio
GSPSAT
Greenville
Wed 10/21
6:00 am-3:12 pm
1 stop10h 12m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$140
GreenvilleSan Antonio
GSP Greenville - SAT San Antonio
GSPSAT
Greenville
Tue 10/27
5:50 am-3:13 pm
1 stop10h 23m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$140
GreenvilleSan Antonio
GSP Greenville - SAT San Antonio
GSPSAT
Greenville
Sat 10/24
2:51 pm-10:51 pm
2 stops9h 00m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$145
Quickest round-trip
CharlestonSan Antonio
CHS Charleston - SAT San Antonio
CHSSAT
Charleston
Wed 10/21
7:04 pm-10:56 pm
1 stop4h 52m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$170
Myrtle BeachSan Antonio
MYR Myrtle Beach Intl - SAT San Antonio
MYRSAT
Myrtle Beach Intl
Wed 10/21
6:58 pm-12:33 am
1 stop6h 35m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$170
Myrtle BeachSan Antonio
MYR Myrtle Beach Intl - SAT San Antonio
MYRSAT
Myrtle Beach Intl
Mon 11/23
6:51 pm-12:33 am
1 stop6h 42m
San Antonio
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$170
Showing 1-10 of 56 resultsSorted by cheapest first
Best time to book a flight from South Carolina to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from South Carolina with our price prediction graph.
GSP-SAT
MYR-SAT
CHS-SAT
CAE-SAT
FLO-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to San Antonio
USSC-SAT
GSP-SAT
MYR-SAT
CHS-SAT
CAE-SAT
What is the cheapest month to book a flight from South Carolina to San Antonio?
Currently, January is the cheapest month in which you can book a flight from South Carolina to San Antonio (average of $346). Flying from South Carolina to San Antonio in December is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Carolina to San Antonio?
Airfare is below average for this route at the moment.
South Carolina to San Antonio flights typically cost between $398 and $487 in October.The cheapest round-trip price found within the last 5 days was $335 on American Airlines (Oct 31-Nov 2).
Related info for your journey
Find useful and relevant information for your journey from South Carolina to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Carolina to San Antonio
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Complete your trip
Complete your trip to San Antonio by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to San Antonio by cabin class
Find flights from South Carolina to San Antonio, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and San Antonio flights
Browse other South Carolina and San Antonio flight options. Last updated on September 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Antonio
Explore flights to San Antonio departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 29, 2026.
South Carolina to San Antonio flights
Consider these flights traveling from South Carolina to San Antonio.
Top 3 airlines flying from South Carolina to San Antonio
Discover the top 3 airlines that operate flights from South Carolina to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$429 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$426 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$278 | Average$425 | FlexibilityNo cancel fee | On-time63% |