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South Carolina

$223+ Cheap flights from Rochester, MN (RST) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
RST — CHS
Apr 12 — Apr 191
Sun 4/12
Sun 4/19
1 adult, Economy
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Cheap flight deals from Rochester to South Carolina

Cheapest flights from Rochester to South Carolina
Explore the most affordable flight options available from Rochester to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.

This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:45 am
RST
-
GSP
1 stop4h 16m
American Airlines
Tue 4/148:16 pm
GSP
-
RST
1 stop4h 39m
American Airlines
Deal found 3/9$278
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:30 am
RST
-
CLT
1 stop7h 02m
Delta
Sun 5/106:15 am
CLT
-
RST
1 stop5h 38m
Delta
Deal found 3/9$278
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:36 am
RST
-
CHS
2 stops6h 53m
American Airlines
Thu 4/236:38 pm
CHS
-
RST
1 stop6h 17m
American Airlines
Deal found 3/9$294
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:38 am
RST
-
GSP
1 stop4h 26m
American Airlines
Sat 5/306:43 pm
GSP
-
RST
1 stop6h 22m
American Airlines
Deal found 3/12$298
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:30 am
RST
-
CLT
1 stop4h 05m
Delta
Mon 5/116:15 am
CLT
-
RST
1 stop5h 38m
Delta
Deal found 3/9$303
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:32 am
RST
-
CLT
1 stop5h 37m
Delta
Sat 4/185:30 am
CLT
-
RST
2 stops6h 22m
Delta
Deal found 3/11$304
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:19 pm
RST
-
CHS
1 stop5h 29m
United Airlines
Sun 6/76:00 am
CHS
-
RST
1 stop5h 22m
United Airlines
Deal found 3/11$308
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:06 am
RST
-
MYR
2 stops8h 24m
American Airlines
Sat 9/55:07 pm
MYR
-
RST
1 stop7h 36m
American Airlines
Deal found 3/12$314
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:00 am
RST
-
CHS
1 stop7h 06m
Delta
Wed 4/85:27 am
CHS
-
RST
2 stops6h 23m
Delta
Deal found 3/11$314
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:19 pm
RST
-
GSP
1 stop4h 58m
United Airlines
Sun 5/316:00 am
GSP
-
RST
1 stop5h 22m
United Airlines
Deal found 3/9$319
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:46 pm
RST
-
CHS
2 stops6h 30m
Delta
Wed 4/85:27 am
CHS
-
RST
2 stops6h 23m
Delta
Deal found 3/11$319
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:53 am
RST
-
CHS
1 stop4h 41m
American Airlines
Sat 4/117:07 am
CHS
-
RST
1 stop4h 59m
American Airlines
Deal found 3/11$323

Find flight deals from Rochester to South Carolina

Keep the following information in mind while searching for Rochester to South Carolina flight deals. Data was last updated March 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$278
(American Airlines)

One-way from

$223
(United Airlines)
Provider with most accurate pricing for Rochester-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Rochester-Myrtle Beach Intl flights.
Search Deals
From Rochester to South Carolina
Search Deals
One-way flight from Rochester to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Rochester to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Rochester to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Tue 4/7

5:45 am-11:01 am

1 stop4h 16m

Greenville

Tue 4/14

8:16 pm-11:55 pm

1 stop4h 39m

$278

RochesterCharlotte

RST - CLT

RSTCLT

Rochester

Thu 5/7

5:30 am-1:32 pm

1 stop7h 02m

Charlotte Douglas

Sat 5/9

11:26 am-4:05 pm

1 stop5h 39m

$278

RochesterCharlotte

RST - CLT

RSTCLT

Rochester

Thu 5/7

5:40 am-11:50 am

1 stop5h 10m

Charlotte Douglas

Sun 5/10

7:06 am-11:06 am

1 stop5h 00m

$278

RochesterCharlotte

RST - CLT

RSTCLT

Rochester

Thu 5/21

5:00 pm-12:45 am

1 stop6h 45m

Charlotte Douglas

Mon 5/25

8:05 am-2:44 pm

1 stop7h 39m

$298

RochesterCharlotte

RST - CLT

RSTCLT

Rochester

Fri 7/10

11:15 am-6:58 pm

1 stop6h 43m

Charlotte Douglas

Sun 7/12

6:20 am-10:46 am

1 stop5h 26m

$298

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Wed 5/27

5:38 am-11:04 am

1 stop4h 26m

Greenville

Sat 5/30

6:43 pm-12:05 am

1 stop6h 22m

$298

RochesterCharlotte

RST - CLT

RSTCLT

Rochester

Fri 5/8

11:33 am-6:51 pm

1 stop6h 18m

Charlotte Douglas

Mon 5/11

6:15 am-10:53 am

1 stop5h 38m

$298

RochesterCharlotte

RST - CLT

RSTCLT

Rochester

Tue 4/14

11:32 am-6:09 pm

1 stop5h 37m

Charlotte Douglas

Sat 4/18

6:00 am-10:52 am

1 stop5h 52m

$298

RochesterGreenville

RST - GSP

RSTGSP

Rochester

Wed 5/27

3:19 pm-9:17 pm

1 stop4h 58m

Greenville

Sun 5/31

6:00 am-10:22 am

1 stop5h 22m

$319

RochesterCharleston

RST - CHS

RSTCHS

Rochester

Fri 4/3

4:46 pm-12:16 am

2 stops6h 30m

Charleston

Fri 4/10

5:27 am-10:50 am

2 stops6h 23m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/11

Showing 1-10 of 48 resultsSorted by cheapest first
1
2
3
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5

Best time to book a flight from Rochester to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Rochester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Rochester to South Carolina

What is the cheapest month to book a flight from Rochester, Minnesota to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Rochester, Minnesota to South Carolina (average of $80). Flying from Rochester, Minnesota to South Carolina in July is currently the most expensive (average of $254). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 13, 2026.
Read reviews from past customers who have flown American Airlines from Rochester to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,449 reviews

Comfort

7.2

Overall

7.1

Crew

7.9

Boarding

7.5

Food

6.4

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,449 reviews
American Airlines
7.1
Good
11,449 reviews

Comfort

7.2

Overall

7.1

Crew

7.9

Boarding

7.5

Food

6.4

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Rochester to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Rochester to South Carolina?

    Rochester (RST), located 7.0 mi from the city center, is the airport you fly out of when you book flights from Rochester to South Carolina.

  • How long is the flight from Rochester, Minnesota to South Carolina?

    American Airlines, Delta, and United Airlines can get you from Rochester, Minnesota to South Carolina in just under 4h 16m. Your travel time can differ by up to 2h 46m. There are 828 mi between Rochester, Minnesota and South Carolina. This flight may include one or multiple stops.

  • What are the most popular routes from Rochester, Minnesota to South Carolina?

    Most travelers choose Rochester - Charlotte Douglas, Rochester - Greenville or Rochester - Myrtle Beach Intl when deciding on the best route from Rochester, Minnesota to South Carolina.

  • Can I find deals for flights from Rochester to South Carolina that include hotel bookings?

    Yes. In addition to deals on Rochester to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Rochester to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Rochester to South Carolina.

  • Can I find deals for business class flights from Rochester to South Carolina?

    Yes. Cheapflights offers flight deals from Rochester to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Rochester, Minnesota to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Rochester, Minnesota to South Carolina (average of $80). Flying from Rochester, Minnesota to South Carolina in July is currently the most expensive (average of $254). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Rochester to South Carolina

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Top airline flying from Rochester to South Carolina

Discover the top airline that operate flights from Rochester to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$423FlexibilityNo cancel feeOn-time71%

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