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$199+ Cheap flights from Roanoke (ROA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — CHS
лис. 28 — груд. 51
пт 11/28
пт 12/5
1 adult, Economy
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Cheap flight deals from Roanoke to South Carolina

Keep the following information in mind while searching for Roanoke to South Carolina flight deals. Data was last updated жовтень 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$219
(Delta)

One-way from

$199
(Kiwi.com)
Provider with most accurate pricing for Roanoke-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Roanoke-Myrtle Beach Intl flights.
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From Roanoke to South Carolina
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One-way flight from Roanoke to South Carolina
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Find flight deals from Roanoke to South Carolina

Cheapest flights from Roanoke to South Carolina
Explore the most affordable flight options available from Roanoke to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on жовтень 29, 2025.

This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
сб 12/68:00 pmROA - MYR
1 stop3h 43mDelta
вт 12/910:32 amMYR - ROA
1 stop4h 36mDelta
Deal found 10/28$219
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
сб 11/155:05 amROA - MYR
1 stop5h 28mAmerican Airlines
сб 11/228:07 pmMYR - ROA
1 stop3h 58mAmerican Airlines
Deal found 10/28$224
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
сб 11/152:32 pmROA - MYR
2 stops7h 33mAmerican Airlines
ср 11/196:23 amMYR - ROA
1 stop3h 22mAmerican Airlines
Deal found 10/27$229
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
сб 11/156:00 amROA - MYR
1 stop3h 50mDelta
ср 11/196:00 amMYR - ROA
1 stop4h 40mDelta
Deal found 10/28$234
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
вт 11/117:20 amROA - CHS
1 stop6h 15mAmerican Airlines
сб 11/156:45 pmCHS - ROA
1 stop4h 06mAmerican Airlines
Deal found 10/27$239
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
чт 11/136:00 amROA - MYR
1 stop3h 50mDelta
пн 11/176:50 pmMYR - ROA
1 stop5h 25mDelta
Deal found 10/28$249
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
пт 12/58:00 pmROA - CHS
1 stop3h 50mDelta
нд 12/76:30 amCHS - ROA
1 stop4h 10mDelta
Deal found 10/27$254
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ср 10/296:45 amROA - MYR
1 stop7h 24mAmerican Airlines
ср 11/56:23 amMYR - ROA
1 stop5h 39mAmerican Airlines
Deal found 10/28$259
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
нд 11/96:30 amROA - CHS
1 stop4h 17mAmerican Airlines
нд 11/165:10 amCHS - ROA
1 stop3h 40mAmerican Airlines
Deal found 10/27$259
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
пн 12/18:06 pmROA - CHS
1 stop4h 07mAmerican Airlines
ср 12/1010:20 amCHS - ROA
1 stop4h 46mAmerican Airlines
Deal found 10/27$264
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
пт 10/316:00 amROA - MYR
1 stop3h 37mAmerican Airlines
нд 11/25:03 amMYR - ROA
1 stop3h 47mAmerican Airlines
Deal found 10/27$269
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
вт 12/29:01 amROA - CLT
Nonstop1h 37mAmerican Airlines
ср 12/241:10 pmCLT - ROA
Nonstop1h 12mAmerican Airlines
Deal found 10/27$283

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated жовтень 29, 2025.
Use the filters below to find and compare flights from Roanoke to South Carolina that are best for you.

Fly from

Roanoke

Fly to

South Carolina

Route

Depart

Return

Price

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

сб 12/6

6:00 am-9:35 am

1 stop3h 35m

Myrtle Beach Intl

вт 12/9

10:32 am-3:08 pm

1 stop4h 36m

$219

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

сб 12/6

6:30 am-10:42 am

1 stop4h 12m

Myrtle Beach Intl

вт 12/9

7:30 am-1:37 pm

1 stop6h 07m

$219

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

сб 11/15

5:05 am-8:39 am

1 stop3h 34m

Myrtle Beach Intl

ср 11/19

7:30 am-1:34 pm

1 stop6h 04m

$224

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

сб 11/15

5:05 am-10:33 am

1 stop5h 28m

Myrtle Beach Intl

сб 11/22

8:07 pm-12:05 am

1 stop3h 58m

$224

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

ср 2/18

3:25 pm-7:09 pm

1 stop3h 44m

Charleston

сб 2/21

6:30 am-10:33 am

1 stop4h 03m

$229

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

пт 2/13

2:51 pm-6:25 pm

1 stop3h 34m

Charleston

нд 2/15

7:15 pm-10:26 pm

1 stop3h 11m

$229

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

чт 12/25

6:00 am-10:26 am

1 stop4h 26m

Myrtle Beach Intl

пн 12/29

6:59 pm-12:07 am

1 stop5h 08m

$234

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

чт 11/13

5:05 am-8:29 am

1 stop3h 24m

Charleston

нд 11/16

5:10 am-8:50 am

1 stop3h 40m

$239

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

чт 11/13

6:00 am-9:50 am

1 stop3h 50m

Myrtle Beach Intl

пн 11/17

6:50 pm-12:15 am

1 stop5h 25m

$249

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

пн 12/1

8:06 pm-12:13 am

1 stop4h 07m

Charleston

ср 12/10

10:20 am-3:06 pm

1 stop4h 46m

$264

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 35 results
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Best time to book a flight from Roanoke to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to South Carolina

What is the cheapest month to book a flight from Roanoke to South Carolina?

Currently, July is the cheapest month in which you can book a flight from Roanoke to South Carolina (average of $207). Flying from Roanoke to South Carolina in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SC?

Find hourly flight availability from Roanoke to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated жовтень 29, 2025.

It’s optimal to fly from Roanoke to South Carolina in the afternoon. By choosing this option you can save up to 30% on the cost of your flight, compared to a flight at noon.

How much does it cost to fly round-trip from Roanoke to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated жовтень 29, 2025.
Read through reviews of airlines operating flights from Roanoke to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,032 reviews

Comfort

7.2

Entertainment

6.9

Crew

8.0

Food

6.4

Boarding

7.5

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,032 reviews
American Airlines
7.2
Good
11,032 reviews

Comfort

7.2

Entertainment

6.9

Crew

8.0

Food

6.4

Boarding

7.5

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Roanoke to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to South Carolina?

    If you book a flight to South Carolina from Roanoke, you will be flying from Roanoke, which is the city’s only airport. Roanoke (ROA) is located 4.2 mi from the center of Roanoke.

  • How long is the flight from Roanoke to South Carolina?

    Delta and American Airlines can get you from Roanoke to South Carolina in just under 3h 35m. Your travel time can differ by up to 37m. The distance between Roanoke and South Carolina is about 258 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Roanoke to South Carolina one-way?

    $205 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $300 and $704, respectively.

  • What are the most popular routes from Roanoke to South Carolina?

    When deciding which route to take from Roanoke to South Carolina consider Roanoke - Charleston, Roanoke - Charlotte Douglas or Roanoke - Myrtle Beach Intl as they are the most popular.

  • Can I find deals for flights from Roanoke to South Carolina that include hotel bookings?

    Yes. In addition to deals on Roanoke to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to South Carolina.

  • Can I find deals for business class flights from Roanoke to South Carolina?

    Yes. Cheapflights offers flight deals from Roanoke to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to South Carolina?

    Currently, July is the cheapest month in which you can book a flight from Roanoke to South Carolina (average of $207). Flying from Roanoke to South Carolina in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Roanoke to South Carolina

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Top airline flying from Roanoke to South Carolina

Discover the top airline that operate flights from Roanoke to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated жовтень 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$218Average$447FlexibilityNo cancel feeOn-time71%

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