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$180+ Cheap flights from Roanoke (ROA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — CHS
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Roanoke to South Carolina

Keep the following information in mind while searching for Roanoke to South Carolina flight deals. Data was last updated July 29, 2025.

Round-trip from

$229
(Delta)

One-way from

$180
(Delta)
From Roanoke to South Carolina
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One-way flight from Roanoke to South Carolina
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Find flight deals from Roanoke to South Carolina

Cheapest flights from Roanoke to South Carolina
Explore the most affordable flight options available from Roanoke to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/106:00 amROA - CHS
1 stop3h 19mDelta
Sat 9/205:35 pmCHS - ROA
1 stop6h 22mDelta
Deal found 7/27$229
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/193:14 pmROA - CHS
2 stops7h 49mAmerican Airlines
Tue 8/265:33 pmCHS - ROA
1 stop3h 05mAmerican Airlines
Deal found 7/29$234
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/27:29 pmROA - CLT
Nonstop1h 21mAmerican Airlines
Wed 9/1010:40 amCLT - ROA
Nonstop1h 31mAmerican Airlines
Deal found 7/27$283
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/216:00 amROA - MYR
1 stop4h 13mAmerican Airlines
Sun 10/56:05 pmMYR - ROA
1 stop6h 06mAmerican Airlines
Deal found 7/29$307
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/267:51 pmROA - MYR
1 stop3h 58mDelta
Sat 8/306:00 amMYR - ROA
1 stop4h 30mDelta
Deal found 7/27$357
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:20 amROA - CHS
2 stops17h 38mUnited Airlines
Tue 9/167:45 pmCHS - ROA
1 stop3h 39mUnited Airlines
Deal found 7/27$388
This Mytrip deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/108:13 pmROA - MYR
2 stops22h 39mMultiple Airlines
Sat 8/167:34 pmMYR - ROA
2 stops23h 49mMultiple Airlines
Deal found 7/27$412
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/26:45 amROA - CLT
2 stops17h 14mUnited Airlines
Wed 9/1010:25 amCLT - ROA
1 stop3h 38mUnited Airlines
Deal found 7/27$425
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/307:00 amROA - MYR
1 stop7h 35mUnited Airlines
Fri 8/15:12 pmMYR - ROA
2 stops30h 03mUnited Airlines
Deal found 7/26$503
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/231:02 pmROA - CHS
3 stops31h 41mMultiple Airlines
Mon 10/2710:30 amCHS - ROA
3 stops21h 53mMultiple Airlines
Deal found 7/29$626
This Mytrip deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/24:18 pmROA - MYR
2 stops18h 12mAllegiant Air
Sat 8/97:26 pmMYR - ROA
2 stops25h 30mAllegiant Air
Deal found 7/27$688
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/103:42 pmROA - CLT
1 stop4h 39mDelta
Sun 10/127:30 pmCLT - ROA
1 stop4h 39mDelta
Deal found 7/28$1,327

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Roanoke to South Carolina that are best for you.

Fly from

Roanoke

Fly to

South Carolina

Route

Depart

Return

Price

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Wed 9/10

6:00 am-11:50 am

1 stop5h 50m

Charleston

Tue 9/16

10:21 am-2:51 pm

1 stop4h 30m

$229

RoanokeCharlotte

ROA - CLT

ROACLT

Roanoke

Tue 9/2

7:29 pm-8:50 pm

Nonstop1h 21m

Charlotte Douglas

Wed 9/10

10:40 am-12:11 pm

Nonstop1h 31m

$283

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Sun 9/14

8:09 pm-12:05 am

1 stop3h 56m

Charleston

Sat 9/20

5:26 pm-11:04 pm

1 stop5h 38m

$289

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Sun 9/21

6:00 am-10:13 am

1 stop4h 13m

Myrtle Beach Intl

Sun 10/5

6:05 pm-12:11 am

1 stop6h 06m

$307

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Tue 8/26

7:51 pm-11:49 pm

1 stop3h 58m

Myrtle Beach Intl

Sat 8/30

6:00 am-10:30 am

1 stop4h 30m

$357

RoanokeCharleston

ROA - CHS

ROACHS

Roanoke

Fri 9/12

6:20 am-11:58 pm

2 stops17h 38m

Charleston

Tue 9/16

7:45 pm-11:24 pm

1 stop3h 39m

$388

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Sun 8/10

8:13 pm-6:52 pm

2 stops22h 39m

Myrtle Beach Intl

Sat 8/16

7:34 pm-7:23 pm

2 stops23h 49m

$412

RoanokeCharlotte

ROA - CLT

ROACLT

Roanoke

Tue 9/2

6:45 am-11:59 pm

2 stops17h 14m

Charlotte Douglas

Wed 9/10

10:25 am-2:03 pm

1 stop3h 38m

$425

RoanokeMyrtle Beach

ROA - MYR

ROAMYR

Roanoke

Sat 9/6

7:35 pm-10:36 am

2 stops15h 01m

Myrtle Beach Intl

Sat 9/13

4:45 pm-10:06 am

1 stop17h 21m

$548

RoanokeCharlotte

ROA - CLT

ROACLT

Roanoke

Fri 10/10

3:42 pm-8:21 pm

1 stop4h 39m

Charlotte Douglas

Sun 10/12

7:30 pm-12:09 am

1 stop4h 39m

$1,327

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Showing 1-10 of 18 results
1
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Best time to book a flight from Roanoke to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to South Carolina

What is the cheapest month to book a flight from Roanoke to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Roanoke to South Carolina (average of $217). Flying from Roanoke to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to SC?

Find hourly flight availability from Roanoke to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Roanoke to South Carolina as you normally would.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 29, 2025.
Read through reviews of airlines operating flights from Roanoke to South Carolina, such as Delta, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Crew

8.5

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Roanoke to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to South Carolina?

    If you book a flight to South Carolina from Roanoke, you will be flying from Roanoke, which is the city’s only airport. Roanoke (ROA) is located 4.2 mi from the center of Roanoke.

  • What are the cheapest airlines to fly from Roanoke to South Carolina one-way?

    $180 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $228 and $283, respectively.

  • What are the most popular routes from Roanoke to South Carolina?

    When deciding which route to take from Roanoke to South Carolina consider Roanoke - Myrtle Beach Intl, Roanoke - Charlotte Douglas or Roanoke - Charleston as they are the most popular.

  • Can I find deals for flights from Roanoke to South Carolina that include hotel bookings?

    Yes. In addition to deals on Roanoke to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to South Carolina.

  • Can I find deals for business class flights from Roanoke to South Carolina?

    Yes. Cheapflights offers flight deals from Roanoke to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Roanoke to South Carolina (average of $217). Flying from Roanoke to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Roanoke to South Carolina

Discover the top airline that operate flights from Roanoke to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$216Average$419FlexibilityNo cancel feeOn-time71%

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