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$74+ Cheap flights from Myrtle Beach (MYR) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CHS
Jan 16 — Jan 231
Fri 1/16
Fri 1/23
1 adult, Economy
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Cheap flight deals from Myrtle Beach to South Carolina

Cheapest flights from Myrtle Beach to South Carolina
Explore the most affordable flight options available from Myrtle Beach to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 17, 2025.

This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:34 pmMYR - CLT
Nonstop1h 09mAmerican Airlines
Wed 12/317:02 pmCLT - MYR
1 stop24h 10mAmerican Airlines
Deal found 12/17$275
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:48 pmMYR - CLT
Nonstop1h 07mAmerican Airlines
Thu 12/254:30 pmCLT - MYR
Nonstop1h 04mAmerican Airlines
Deal found 12/16$281
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:54 amMYR - CLT
1 stop10h 39mMultiple Airlines
Sun 1/45:38 pmCLT - MYR
1 stop15h 11mMultiple Airlines
Deal found 12/16$284
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:54 amMYR - GSP
1 stop6h 01mMultiple Airlines
Sun 1/411:33 amGSP - MYR
1 stop7h 04mMultiple Airlines
Deal found 12/16$317
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:29 amMYR - CHS
1 stop7h 02mBreeze Airways
Wed 12/249:09 pmCHS - MYR
1 stop11h 40mBreeze Airways
Deal found 12/17$342
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:32 pmMYR - CLT
1 stop18h 24mMultiple Airlines
Tue 12/309:38 pmCLT - MYR
1 stop20h 30mMultiple Airlines
Deal found 12/16$346
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:32 pmMYR - CLT
1 stop25h 07mSpirit Airlines
Tue 12/309:38 pmCLT - MYR
1 stop20h 30mSpirit Airlines
Deal found 12/17$347
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:13 pmMYR - CLT
1 stop11h 20mAmerican Airlines
Sun 12/288:15 amCLT - MYR
Nonstop1h 05mAmerican Airlines
Deal found 12/14$355
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:32 pmMYR - CHS
2 stops15h 15mMultiple Airlines
Wed 12/249:09 pmCHS - MYR
1 stop11h 40mMultiple Airlines
Deal found 12/17$361
This Cheapflightsfares deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:54 amMYR - CLT
1 stop10h 39mSpirit Airlines
Thu 12/257:00 amCLT - MYR
1 stop11h 08mSpirit Airlines
Deal found 12/16$404
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amMYR - GSP
1 stop4h 11mAmerican Airlines
Sat 1/36:20 pmGSP - MYR
1 stop5h 35mAmerican Airlines
Deal found 12/15$407
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:34 pmMYR - CLT
Nonstop1h 09mAmerican Airlines
Sun 1/410:51 pmCLT - MYR
Nonstop1h 04mAmerican Airlines
Deal found 12/16$427

Find flight deals from Myrtle Beach to South Carolina

Keep the following information in mind while searching for Myrtle Beach to South Carolina flight deals. Data was last updated December 17, 2025.

Round-trip from

$178
(Kiwi.com)

One-way from

$74
(Priceline)
From Myrtle Beach Intl to South Carolina
Search Deals
One-way flight from Myrtle Beach Intl to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
Use the filters below to find and compare flights from Myrtle Beach to South Carolina that are best for you.

Fly from

Myrtle Beach

Fly to

South Carolina

Route

Depart

Return

Price

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 2/26

10:02 am-7:49 pm

1 stop9h 47m

Charlotte Douglas

Mon 3/2

3:12 pm-2:44 pm

1 stop23h 32m

$178

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 1/8

8:15 pm-8:11 am

1 stop11h 56m

Charlotte Douglas

Sun 1/11

7:43 pm-7:20 pm

1 stop23h 37m

$191

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 2/26

9:09 am-6:02 pm

1 stop8h 53m

Charlotte Douglas

Mon 3/2

7:05 pm-2:44 pm

2 stops19h 39m

$198

Myrtle BeachCharleston

MYR - CHS

MYRCHS

Myrtle Beach Intl

Mon 1/12

10:00 am-4:10 pm

1 stop6h 10m

Charleston

Mon 1/19

5:05 pm-2:42 pm

1 stop21h 37m

$199

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Mon 2/2

9:58 am-6:48 pm

1 stop8h 50m

Charlotte Douglas

Wed 2/4

6:00 am-7:10 pm

1 stop13h 10m

$201

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Fri 1/9

10:00 am-11:59 pm

1 stop13h 59m

Charlotte Douglas

Sun 1/11

7:43 pm-7:20 pm

1 stop23h 37m

$205

Myrtle BeachCharleston

MYR - CHS

MYRCHS

Myrtle Beach Intl

Thu 1/1

6:00 am-1:10 pm

1 stop7h 10m

Charleston

Mon 1/5

2:15 pm-11:59 pm

1 stop9h 44m

$206

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Thu 1/8

8:15 pm-8:11 am

1 stop11h 56m

Charlotte Douglas

Sun 1/11

8:46 pm-7:20 pm

2 stops22h 34m

$208

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Mon 2/2

10:00 am-6:48 pm

2 stops8h 48m

Charlotte Douglas

Wed 2/4

6:00 am-7:10 pm

1 stop13h 10m

$217

Myrtle BeachCharlotte

MYR - CLT

MYRCLT

Myrtle Beach Intl

Fri 1/23

9:58 am-8:58 pm

1 stop11h 00m

Charlotte Douglas

Sat 1/24

9:07 pm-2:42 pm

1 stop17h 35m

$226

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 33 results
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Best time to book a flight from Myrtle Beach to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to South Carolina

What is the cheapest time of day to fly from MYR to SC?

Find hourly flight availability from Myrtle Beach to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 17, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 55% on flights from Myrtle Beach to South Carolina by exploring options for tickets in the afternoon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 17, 2025.
Peruse reviews from past customers who have flown with American Airlines from Myrtle Beach to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,049 reviews

Entertainment

6.9

Food

6.5

Crew

8.0

Boarding

7.5

Overall

7.2

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,049 reviews
American Airlines
7.2
Good
11,049 reviews

Entertainment

6.9

Food

6.5

Crew

8.0

Boarding

7.5

Overall

7.2

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to South Carolina?

    Most people fly from Myrtle Beach Intl (MYR) if they book a flight from Myrtle Beach to South Carolina. Myrtle Beach Intl is conveniently located just 2.1 mi from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to South Carolina?

    Departing from Myrtle Beach to South Carolina will take you 3h 16m. Myrtle Beach and South Carolina are separated by a distance of 206 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Myrtle Beach to South Carolina?

    While some choose either Myrtle Beach Intl - Greenville or Myrtle Beach Intl - Charleston, Myrtle Beach Intl - Charlotte Douglas is the most popular route from Myrtle Beach to South Carolina.

  • Can I find deals for flights from Myrtle Beach to South Carolina that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to South Carolina.

  • Can I find deals for business class flights from Myrtle Beach to South Carolina?

    Yes. Cheapflights offers flight deals from Myrtle Beach to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Myrtle Beach to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Myrtle Beach to South Carolina

Discover the top airline that operate flights from Myrtle Beach to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$176Average$336FlexibilityNo cancel feeOn-time71%

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