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South Carolina

$260+ Cheap flights from Mobile (MOB) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/4. Fares are subject to change and may not be available on all flights or dates of travel.
MOB — CHS
Feb 21 — Feb 281
Sat 2/21
Sat 2/28
1 adult, Economy
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Cheap flight deals from Mobile to South Carolina

Cheapest flights from Mobile to South Carolina
Explore the most affordable flight options available from Mobile to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 22, 2026.

This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:15 am
MOB
-
GSP
1 stop3h 50m
Delta
Sat 3/218:30 am
GSP
-
MOB
1 stop4h 25m
Delta
Deal found 1/20$317
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:45 pm
MOB
-
SAV
1 stop4h 12m
American Airlines
Sun 3/15:00 am
SAV
-
MOB
1 stop6h 15m
American Airlines
Deal found 1/21$347
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:15 pm
MOB
-
SAV
1 stop3h 49m
Delta
Sun 10/46:50 pm
SAV
-
MOB
1 stop5h 05m
Delta
Deal found 1/21$363
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2612:42 pm
MOB
-
GSP
1 stop5h 12m
Delta
Sun 3/295:40 am
GSP
-
MOB
1 stop3h 51m
Delta
Deal found 1/20$367
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:15 pm
MOB
-
CHS
1 stop3h 42m
Delta
Sun 6/145:30 am
CHS
-
MOB
1 stop4h 00m
Delta
Deal found 1/20$387
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:41 pm
MOB
-
SAV
1 stop4h 13m
American Airlines
Tue 2/246:25 am
SAV
-
MOB
1 stop4h 47m
American Airlines
Deal found 1/20$387
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/174:15 pm
MOB
-
CHS
1 stop3h 26m
Delta
Sun 6/215:30 am
CHS
-
MOB
1 stop4h 00m
Delta
Deal found 1/21$389
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1311:12 am
MOB
-
CLT
1 stop24h 00m
American Airlines
Sun 6/143:04 pm
CLT
-
MOB
Nonstop2h 02m
American Airlines
Deal found 1/20$401
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:41 am
MOB
-
CLT
Nonstop1h 56m
American Airlines
Sat 2/2810:40 pm
CLT
-
MOB
Nonstop2h 11m
American Airlines
Deal found 1/20$405
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/47:05 pm
MOB
-
GSP
1 stop3h 45m
Delta
Sun 2/86:50 am
GSP
-
MOB
1 stop5h 55m
Delta
Deal found 1/20$407
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/57:05 pm
MOB
-
SAV
1 stop3h 53m
Delta
Mon 2/95:49 pm
SAV
-
MOB
1 stop5h 54m
Delta
Deal found 1/20$407
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:48 pm
MOB
-
GSP
1 stop4h 06m
Delta
Sun 3/157:59 pm
GSP
-
MOB
1 stop4h 29m
Delta
Deal found 1/20$417

Find flight deals from Mobile to South Carolina

Keep the following information in mind while searching for Mobile to South Carolina flight deals. Data was last updated January 22, 2026.

Round-trip from

$317
(Delta)

One-way from

$260
(American Airlines)
From Mobile to South Carolina
Search Deals
One-way flight from Mobile to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mobile to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from Mobile to South Carolina that are best for you.

Fly from

Mobile

Fly to

South Carolina

Route

Depart

Return

Price

MobileGreenville

MOB - GSP

MOBGSP

Mobile

Tue 3/17

6:15 am-11:05 am

1 stop3h 50m

Greenville

Sat 3/21

8:30 am-11:55 am

1 stop4h 25m

$317

MobileSavannah

MOB - SAV

MOBSAV

Mobile

Fri 2/27

6:45 pm-11:57 pm

1 stop4h 12m

Savannah/Hilton Head

Sun 3/1

5:00 am-10:15 am

1 stop6h 15m

$347

MobileGreenville

MOB - GSP

MOBGSP

Mobile

Thu 3/26

12:42 pm-6:54 pm

1 stop5h 12m

Greenville

Sun 3/29

5:40 am-8:31 am

1 stop3h 51m

$367

MobileSavannah

MOB - SAV

MOBSAV

Mobile

Tue 2/17

5:41 pm-10:54 pm

1 stop4h 13m

Savannah/Hilton Head

Tue 2/24

6:25 am-10:12 am

1 stop4h 47m

$387

MobileCharleston

MOB - CHS

MOBCHS

Mobile

Fri 6/12

7:15 pm-11:57 pm

1 stop3h 42m

Charleston

Sun 6/14

5:30 am-8:30 am

1 stop4h 00m

$387

MobileCharleston

MOB - CHS

MOBCHS

Mobile

Wed 6/17

4:15 pm-8:41 pm

1 stop3h 26m

Charleston

Sun 6/21

5:30 am-8:30 am

1 stop4h 00m

$389

MobileCharlotte

MOB - CLT

MOBCLT

Mobile

Tue 2/24

10:41 am-1:37 pm

Nonstop1h 56m

Charlotte Douglas

Sat 2/28

10:40 pm-11:51 pm

Nonstop2h 11m

$405

MobileCharlotte

MOB - CLT

MOBCLT

Mobile

Wed 4/1

10:41 am-1:37 pm

Nonstop1h 56m

Charlotte Douglas

Sat 4/4

10:40 pm-11:51 pm

Nonstop2h 11m

$405

MobileGreenville

MOB - GSP

MOBGSP

Mobile

Wed 2/4

7:05 pm-11:50 pm

1 stop3h 45m

Greenville

Sun 2/8

6:50 am-11:45 am

1 stop5h 55m

$407

MobileSavannah

MOB - SAV

MOBSAV

Mobile

Thu 2/5

7:05 pm-11:58 pm

1 stop3h 53m

Savannah/Hilton Head

Mon 2/9

5:49 pm-10:43 pm

1 stop5h 54m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 49 results
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Best time to book a flight from Mobile to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mobile with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mobile to South Carolina

What is the cheapest month to book a flight from Mobile to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Mobile to South Carolina (average of $96). Flying from Mobile to South Carolina in December is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Mobile to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 22, 2026.
Read through reviews of airlines operating flights from Mobile to South Carolina, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,087 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,087 reviews
Delta
7.9
Good
8,087 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,174 reviews
Delta
7.9
Good
8,087 reviews

Comfort

7.9

Entertainment

7.8

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Mobile to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Mobile to South Carolina?

    Mobile (MOB), located 11.8 mi from the city center, is the airport you fly out of when you book flights from Mobile to South Carolina.

  • How long is the flight from Mobile to South Carolina?

    For as low as $317, Delta can have you in South Carolina from Mobile in 3h 50m. There are 454 mi between Mobile and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Mobile to South Carolina?

    Most travelers choose Mobile - Columbia Metropolitan, Mobile - Charlotte Douglas or Mobile - Charleston when deciding on the best route from Mobile to South Carolina.

  • Can I find deals for flights from Mobile to South Carolina that include hotel bookings?

    Yes. In addition to deals on Mobile to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mobile to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mobile to South Carolina.

  • Can I find deals for business class flights from Mobile to South Carolina?

    Yes. Cheapflights offers flight deals from Mobile to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mobile to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Mobile to South Carolina (average of $96). Flying from Mobile to South Carolina in December is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mobile to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mobile to South Carolina

Discover the top 2 airlines that operate flights from Mobile to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$306Average$465FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$366Average$531FlexibilityNo cancel feeOn-time71%

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