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South Carolina

$222+ Cheap flights from Mobile (MOB) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
MOB — CHS
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Mobile to South Carolina

Cheapest flights from Mobile to South Carolina
Explore the most affordable flight options available from Mobile to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:48 pm
MOB
-
GSP
1 stop4h 06m
Delta
Sat 3/215:40 am
GSP
-
MOB
1 stop3h 51m
Delta
Deal found 2/3$317
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/174:15 pm
MOB
-
CHS
1 stop4h 30m
Delta
Tue 6/232:25 pm
CHS
-
MOB
1 stop4h 54m
Delta
Deal found 1/31$339
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:45 pm
MOB
-
SAV
1 stop4h 12m
American Airlines
Wed 3/115:00 am
SAV
-
MOB
1 stop6h 15m
American Airlines
Deal found 2/1$343
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:17 pm
MOB
-
GSP
1 stop3h 26m
Delta
Sat 2/285:40 am
GSP
-
MOB
1 stop3h 52m
Delta
Deal found 1/31$347
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/216:00 am
MOB
-
GSP
1 stop5h 51m
Delta
Fri 2/275:40 am
GSP
-
MOB
1 stop3h 47m
Delta
Deal found 2/2$377
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:17 pm
MOB
-
SAV
1 stop3h 40m
Delta
Thu 2/265:30 am
SAV
-
MOB
1 stop3h 57m
Delta
Deal found 2/1$377
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:15 pm
MOB
-
CHS
1 stop3h 42m
Delta
Mon 6/227:59 pm
CHS
-
MOB
1 stop3h 56m
Delta
Deal found 1/31$387
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:17 pm
MOB
-
CAE
1 stop3h 30m
Delta
Sun 2/225:35 am
CAE
-
MOB
1 stop3h 52m
Delta
Deal found 2/2$407
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:48 pm
MOB
-
CHS
1 stop4h 28m
Delta
Sun 3/155:27 am
CHS
-
MOB
1 stop4h 04m
Delta
Deal found 2/2$413
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:10 pm
MOB
-
MYR
1 stop21h 10m
Delta
Tue 5/126:00 am
MYR
-
MOB
1 stop3h 29m
Delta
Deal found 2/1$417
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:10 am
MOB
-
CLT
1 stop4h 54m
United Airlines
Tue 9/226:30 am
CLT
-
MOB
1 stop6h 06m
United Airlines
Deal found 2/2$425
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/710:46 am
MOB
-
CLT
Nonstop1h 56m
American Airlines
Sun 3/88:59 am
CLT
-
MOB
Nonstop2h 16m
American Airlines
Deal found 2/1$426

Find flight deals from Mobile to South Carolina

Keep the following information in mind while searching for Mobile to South Carolina flight deals. Data was last updated February 3, 2026.

Round-trip from

$317
(Delta)

One-way from

$222
(American Airlines)
From Mobile to South Carolina
Search Deals
One-way flight from Mobile to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mobile to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Mobile to South Carolina that are best for you.

Fly from

Mobile

Fly to

South Carolina

Route

Depart

Return

Price

MobileGreenville

MOB - GSP

MOBGSP

Mobile

Tue 3/17

6:15 am-11:05 am

1 stop3h 50m

Greenville

Sat 3/21

5:40 am-8:31 am

1 stop3h 51m

$317

MobileSavannah

MOB - SAV

MOBSAV

Mobile

Thu 3/5

6:45 pm-11:57 pm

1 stop4h 12m

Savannah/Hilton Head

Wed 3/11

5:00 am-10:15 am

1 stop6h 15m

$343

MobileGreenville

MOB - GSP

MOBGSP

Mobile

Tue 2/24

7:17 pm-11:43 pm

1 stop3h 26m

Greenville

Sat 2/28

5:40 am-8:32 am

1 stop3h 52m

$347

MobileGreenville

MOB - GSP

MOBGSP

Mobile

Wed 2/25

7:17 pm-11:43 pm

1 stop3h 26m

Greenville

Sat 2/28

5:40 am-8:32 am

1 stop3h 52m

$347

MobileSavannah

MOB - SAV

MOBSAV

Mobile

Thu 2/19

6:45 pm-11:57 pm

1 stop4h 12m

Savannah/Hilton Head

Thu 2/26

8:05 pm-11:51 pm

1 stop4h 46m

$377

MobileGreenville

MOB - GSP

MOBGSP

Mobile

Sat 2/21

6:00 am-12:51 pm

1 stop5h 51m

Greenville

Fri 2/27

5:40 am-8:27 am

1 stop3h 47m

$377

MobileGreenville

MOB - GSP

MOBGSP

Mobile

Sat 2/21

6:00 am-12:51 pm

1 stop5h 51m

Greenville

Thu 2/26

5:40 am-8:27 am

1 stop3h 47m

$377

MobileSavannah

MOB - SAV

MOBSAV

Mobile

Fri 2/20

7:17 pm-11:57 pm

1 stop3h 40m

Savannah/Hilton Head

Fri 2/27

5:30 am-8:27 am

1 stop3h 57m

$377

MobileSavannah

MOB - SAV

MOBSAV

Mobile

Thu 2/19

7:17 pm-11:57 pm

1 stop3h 40m

Savannah/Hilton Head

Thu 2/26

5:30 am-8:27 am

1 stop3h 57m

$377

MobileColumbia

MOB - CAE

MOBCAE

Mobile

Thu 2/19

7:17 pm-11:47 pm

1 stop3h 30m

Columbia Metropolitan

Sun 2/22

5:35 am-8:27 am

1 stop3h 52m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 51 results
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Best time to book a flight from Mobile to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Mobile with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mobile to South Carolina

What is the cheapest month to book a flight from Mobile to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Mobile to South Carolina (average of $96). Flying from Mobile to South Carolina in December is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 3, 2026.
Read through reviews of airlines operating flights from Mobile to South Carolina, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,132 reviews

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,132 reviews
Delta
7.9
Good
8,132 reviews

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,212 reviews
Delta
7.9
Good
8,132 reviews

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Mobile to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Mobile to South Carolina?

    Mobile (MOB), located 11.8 mi from the city center, is the airport you fly out of when you book flights from Mobile to South Carolina.

  • How long is the flight from Mobile to South Carolina?

    For as low as $317, Delta can have you in South Carolina from Mobile in 3h 50m. There are 454 mi between Mobile and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Mobile to South Carolina?

    Most travelers choose Mobile - Charlotte Douglas, Mobile - Savannah/Hilton Head or Mobile - Charleston when deciding on the best route from Mobile to South Carolina.

  • Can I find deals for flights from Mobile to South Carolina that include hotel bookings?

    Yes. In addition to deals on Mobile to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mobile to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mobile to South Carolina.

  • Can I find deals for business class flights from Mobile to South Carolina?

    Yes. Cheapflights offers flight deals from Mobile to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mobile to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Mobile to South Carolina (average of $96). Flying from Mobile to South Carolina in December is currently the most expensive (average of $266). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Mobile to South Carolina

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Top 2 airlines flying from Mobile to South Carolina

Discover the top 2 airlines that operate flights from Mobile to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$306Average$457FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$366Average$504FlexibilityNo cancel feeOn-time71%

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