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South Carolina

$136+ Cheap flights from Melbourne, FL (MLB) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
MLB — CHS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Melbourne to South Carolina

Cheapest flights from Melbourne to South Carolina
Explore the most affordable flight options available from Melbourne to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:25 amMLB - CLT
Nonstop1h 56mAmerican Airlines
Mon 12/159:50 pmCLT - MLB
Nonstop1h 51mAmerican Airlines
Deal found 10/29$215
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/122:29 pmMLB - CLT
1 stop5h 50mDelta
Sun 12/146:33 amCLT - MLB
1 stop4h 03mDelta
Deal found 10/29$235
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:05 amMLB - CLT
Nonstop2h 00mAmerican Airlines
Wed 11/199:50 pmCLT - MLB
Nonstop1h 55mAmerican Airlines
Deal found 10/29$258
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/153:00 pmMLB - CLT
1 stop3h 28mDelta
Wed 11/196:33 amCLT - MLB
1 stop4h 02mDelta
Deal found 10/29$278
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/157:25 amMLB - CLT
Nonstop1h 56mAmerican Airlines
Tue 12/309:30 amCLT - MLB
Nonstop2h 00mAmerican Airlines
Deal found 10/29$313
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:47 pmMLB - MYR
1 stop4h 56mDelta
Wed 12/106:00 amMYR - MLB
1 stop4h 36mDelta
Deal found 10/29$317
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/263:11 pmMLB - CHS
2 stops17h 26mMultiple Airlines
Wed 12/312:55 pmCHS - MLB
1 stop22h 03mMultiple Airlines
Deal found 10/29$317
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/276:05 amMLB - CHS
1 stop4h 37mAmerican Airlines
Thu 12/46:31 pmCHS - MLB
1 stop5h 52mAmerican Airlines
Deal found 10/30$322
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:05 amMLB - CLT
Nonstop2h 00mAmerican Airlines
Wed 11/129:50 pmCLT - MLB
Nonstop1h 55mAmerican Airlines
Deal found 10/30$328
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:20 amMLB - CLT
Nonstop1h 53mAmerican Airlines
Fri 12/2610:30 pmCLT - MLB
Nonstop1h 42mAmerican Airlines
Deal found 10/30$333
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/226:48 pmMLB - SAV
1 stop3h 49mDelta
Sat 12/67:00 amSAV - MLB
1 stop3h 36mDelta
Deal found 10/29$337
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/62:33 pmMLB - CLT
1 stop3h 57mDelta
Wed 11/129:47 amCLT - MLB
1 stop3h 56mDelta
Deal found 10/30$348

Cheap flight deals from Melbourne to South Carolina

Keep the following information in mind while searching for Melbourne to South Carolina flight deals. Data was last updated October 30, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$215
(American Airlines)

One-way from

$136
(Kiwi.com)

Popular in

August

Cheapest in

February

Average price

$167
Provider with most accurate pricing for Orlando (ORL)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Orlando (ORL)-Myrtle Beach Intl flights.
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From Melbourne to South Carolina
Search Deals
One-way flight from Melbourne to South Carolina
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($17 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Melbourne to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Melbourne to South Carolina that are best for you.

Fly from

Melbourne

Fly to

South Carolina

Route

Depart

Return

Price

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Fri 12/12

7:25 am-9:21 am

Nonstop1h 56m

Charlotte Douglas

Mon 12/15

9:50 pm-11:41 pm

Nonstop1h 51m

$215

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Sat 12/6

6:07 am-8:03 am

Nonstop1h 56m

Charlotte Douglas

Sat 12/13

10:35 pm-12:23 am

Nonstop1h 48m

$215

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Fri 12/12

2:29 pm-8:19 pm

1 stop5h 50m

Charlotte Douglas

Sun 12/14

6:33 am-10:36 am

1 stop4h 03m

$235

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Sat 11/15

6:05 am-8:05 am

Nonstop2h 00m

Charlotte Douglas

Wed 11/19

9:50 pm-11:45 pm

Nonstop1h 55m

$258

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Sat 11/15

3:00 pm-6:28 pm

1 stop3h 28m

Charlotte Douglas

Wed 11/19

6:33 am-10:35 am

1 stop4h 02m

$278

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Mon 12/15

7:25 am-9:21 am

Nonstop1h 56m

Charlotte Douglas

Wed 12/31

9:30 am-11:30 am

Nonstop2h 00m

$313

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

Wed 11/26

3:11 pm-8:37 am

2 stops17h 26m

Charleston

Wed 12/3

12:55 pm-10:58 am

1 stop22h 03m

$317

MelbourneMyrtle Beach

MLB - MYR

MLBMYR

Melbourne

Thu 12/4

6:00 am-9:47 am

1 stop3h 47m

Myrtle Beach Intl

Wed 12/10

6:56 pm-10:49 pm

1 stop3h 53m

$317

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

Thu 11/27

6:05 am-10:42 am

1 stop4h 37m

Charleston

Thu 12/4

6:31 pm-12:23 am

1 stop5h 52m

$322

MelbourneMyrtle Beach

MLB - MYR

MLBMYR

Melbourne

Sat 2/7

6:00 am-9:48 am

1 stop3h 48m

Myrtle Beach Intl

Sat 2/14

4:00 pm-10:44 pm

1 stop6h 44m

$327

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 52 results
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Best time to book a flight from Melbourne to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Melbourne with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Melbourne to South Carolina

What is the cheapest month to book a flight from Melbourne, Florida to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Melbourne, Florida to South Carolina (average of $43). Flying from Melbourne, Florida to South Carolina in December is currently the most expensive (average of $85). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MLB to SC?

Find hourly flight availability from Melbourne to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 29% on flights from Melbourne, Florida to South Carolina by exploring options for tickets in the afternoon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from Melbourne to South Carolina, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Melbourne to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Melbourne to South Carolina?

    Located just 2.7 mi from the city center, Melbourne (MLB) is the airport most travelers will use when flying to South Carolina from Melbourne.

  • How long is the flight from Melbourne, Florida to South Carolina?

    A quick flight from Melbourne, Florida to South Carolina can take about 1h 56m. American Airlines provides one of the quickest options available for as low as $215. There are 492 mi between Melbourne, Florida and South Carolina. This flight may include one or multiple stops.

  • What are the most popular routes from Melbourne, Florida to South Carolina?

    While some choose either Melbourne - Greenville or Melbourne - Charleston, Melbourne - Charlotte Douglas is the most popular route from Melbourne, Florida to South Carolina.

  • Can I find deals for flights from Melbourne to South Carolina that include hotel bookings?

    Yes. In addition to deals on Melbourne to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Melbourne to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Melbourne to South Carolina.

  • Can I find deals for business class flights from Melbourne to South Carolina?

    Yes. Cheapflights offers flight deals from Melbourne to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Melbourne, Florida to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Melbourne, Florida to South Carolina (average of $43). Flying from Melbourne, Florida to South Carolina in December is currently the most expensive (average of $85). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Melbourne to South Carolina

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Top 2 airlines flying from Melbourne to South Carolina

Discover the top 2 airlines that operate flights from Melbourne to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$276Average$415FlexibilityNo cancel feeOn-time71%
DeltaCheapest$282Average$379FlexibilityNo cancel feeOn-timeN/A

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