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South Carolina

$110+ Cheap flights from Melbourne, FL (MLB) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
MLB — CHS
ene. 14 — ene. 211
mié. 1/14
mié. 1/21
1 adult, Economy
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Cheap flight deals from Melbourne to South Carolina

Cheapest flights from Melbourne to South Carolina
Explore the most affordable flight options available from Melbourne to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/316:20 amMLB - CLT
Nonstop1h 53mAmerican Airlines
jue. 1/159:50 pmCLT - MLB
Nonstop1h 50mAmerican Airlines
Deal found 12/15$315
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/3111:30 amMLB - CLT
1 stop3h 55mDelta
jue. 1/155:25 amCLT - MLB
1 stop5h 05mDelta
Deal found 12/15$364
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/206:20 amMLB - CLT
Nonstop1h 53mAmerican Airlines
dom. 12/282:55 pmCLT - MLB
Nonstop1h 43mAmerican Airlines
Deal found 12/14$381
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/212:51 pmMLB - CLT
1 stop4h 19mDelta
mié. 12/316:00 amCLT - MLB
1 stop4h 45mDelta
Deal found 12/14$401
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/296:20 amMLB - CAE
1 stop4h 22mAmerican Airlines
vie. 1/25:07 amCAE - MLB
1 stop6h 23mAmerican Airlines
Deal found 12/13$407
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/296:05 amMLB - GSP
1 stop5h 53mDelta
vie. 1/25:45 amGSP - MLB
1 stop5h 00mDelta
Deal found 12/13$407
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/276:47 pmMLB - CHS
1 stop5h 11mDelta
jue. 1/110:18 amCHS - MLB
1 stop5h 04mDelta
Deal found 12/13$407
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/191:47 pmMLB - CLT
Nonstop1h 51mAmerican Airlines
dom. 12/219:30 amCLT - MLB
Nonstop2h 00mAmerican Airlines
Deal found 12/14$413
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/286:47 pmMLB - MYR
1 stop4h 03mDelta
jue. 1/16:00 amMYR - MLB
1 stop4h 45mDelta
Deal found 12/13$416
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/236:20 amMLB - CLT
Nonstop1h 53mAmerican Airlines
sáb. 12/2710:30 pmCLT - MLB
Nonstop1h 42mAmerican Airlines
Deal found 12/13$432
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/196:47 pmMLB - CLT
1 stop4h 55mDelta
dom. 12/2111:38 amCLT - MLB
1 stop6h 24mDelta
Deal found 12/13$433
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1812:00 pmMLB - CLT
Nonstop1h 52mAmerican Airlines
vie. 12/199:30 amCLT - MLB
Nonstop2h 00mAmerican Airlines
Deal found 12/13$455

Find flight deals from Melbourne to South Carolina

Keep the following information in mind while searching for Melbourne to South Carolina flight deals. Data was last updated diciembre 15, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$255
(Delta)

One-way from

$110
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$278
Provider with most accurate pricing for Orlando (ORL)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Orlando (ORL)-Myrtle Beach Intl flights.
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From Melbourne to South Carolina
Search Deals
One-way flight from Melbourne to South Carolina
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($18 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Melbourne to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 15, 2025.
Use the filters below to find and compare flights from Melbourne to South Carolina that are best for you.

Fly from

Melbourne

Fly to

South Carolina

Route

Depart

Return

Price

MelbourneMyrtle Beach

MLB - MYR

MLBMYR

Melbourne

vie. 1/23

11:24 am-5:59 pm

1 stop6h 35m

Myrtle Beach Intl

dom. 1/25

6:54 pm-10:40 pm

1 stop3h 46m

$255

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

mar. 1/13

6:00 am-11:48 am

1 stop5h 48m

Charleston

dom. 1/18

5:18 pm-9:45 pm

1 stop4h 27m

$271

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

mar. 1/13

4:21 pm-9:08 pm

1 stop4h 47m

Charleston

dom. 1/18

10:18 am-3:51 pm

1 stop5h 33m

$279

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

mié. 12/31

6:20 am-8:13 am

Nonstop1h 53m

Charlotte Douglas

jue. 1/15

9:50 pm-11:40 pm

Nonstop1h 50m

$315

MelbourneColumbia

MLB - CAE

MLBCAE

Melbourne

jue. 2/12

6:00 am-9:28 am

1 stop3h 28m

Columbia Metropolitan

dom. 2/15

6:40 am-10:39 am

1 stop3h 59m

$327

MelbourneSavannah

MLB - SAV

MLBSAV

Melbourne

vie. 1/9

11:24 am-3:55 pm

1 stop4h 31m

Savannah/Hilton Head

vie. 1/16

6:46 pm-10:40 pm

1 stop3h 54m

$337

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

jue. 1/15

4:21 pm-6:18 pm

Nonstop1h 57m

Charlotte Douglas

lun. 1/19

10:16 am-12:09 pm

Nonstop1h 53m

$339

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

vie. 1/30

5:56 pm-7:53 pm

Nonstop1h 57m

Charlotte Douglas

dom. 2/1

2:00 pm-3:51 pm

Nonstop1h 51m

$339

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

sáb. 1/10

6:00 am-9:41 am

1 stop3h 41m

Charlotte Douglas

sáb. 1/17

2:25 pm-5:49 pm

1 stop3h 24m

$340

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

jue. 1/1

6:20 am-10:11 am

1 stop3h 51m

Greenville

jue. 1/8

6:00 am-12:09 pm

1 stop6h 09m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 47 results
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Best time to book a flight from Melbourne to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Melbourne with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Melbourne to South Carolina

What is the cheapest month to book a flight from Melbourne, Florida to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Melbourne, Florida to South Carolina (average of $41). Flying from Melbourne, Florida to South Carolina in January is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MLB to SC?

Find hourly flight availability from Melbourne to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 15, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 40% on flights from Melbourne, Florida to South Carolina by exploring options for tickets in the afternoon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated diciembre 15, 2025.
Read through reviews of airlines operating flights from Melbourne to South Carolina, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,008 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Melbourne to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Melbourne to South Carolina?

    Located just 2.7 mi from the city center, Melbourne (MLB) is the airport most travelers will use when flying to South Carolina from Melbourne.

  • How long is the flight from Melbourne, Florida to South Carolina?

    A quick flight from Melbourne, Florida to South Carolina can take about 4h 47m. Delta provides one of the quickest options available for as low as $279. There are 333 mi between Melbourne, Florida and South Carolina. This flight may include one or multiple stops.

  • What are the most popular routes from Melbourne, Florida to South Carolina?

    While some choose either Melbourne - Charlotte Douglas or Melbourne - Columbia Metropolitan, Melbourne - Savannah/Hilton Head is the most popular route from Melbourne, Florida to South Carolina.

  • Can I find deals for flights from Melbourne to South Carolina that include hotel bookings?

    Yes. In addition to deals on Melbourne to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Melbourne to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Melbourne to South Carolina.

  • Can I find deals for business class flights from Melbourne to South Carolina?

    Yes. Cheapflights offers flight deals from Melbourne to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Melbourne, Florida to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Melbourne, Florida to South Carolina (average of $41). Flying from Melbourne, Florida to South Carolina in January is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Melbourne to South Carolina

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Top 2 airlines flying from Melbourne to South Carolina

Discover the top 2 airlines that operate flights from Melbourne to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$286Average$387FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$301Average$399FlexibilityNo cancel feeOn-time71%

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