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South Carolina

$147+ Cheap flights from Melbourne, FL (MLB) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
MLB — CHS
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Melbourne to South Carolina

Cheapest flights from Melbourne to South Carolina
Explore the most affordable flight options available from Melbourne to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:43 pm
MLB
-
CHS
1 stop5h 11m
Delta
Sat 3/71:26 pm
CHS
-
MLB
1 stop4h 22m
Delta
Deal found 1/27$293
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
MLB
-
GSP
1 stop5h 05m
Delta
Sat 4/115:38 pm
GSP
-
MLB
1 stop4h 03m
Delta
Deal found 1/26$317
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:00 am
MLB
-
CAE
1 stop3h 28m
Delta
Thu 3/56:50 pm
CAE
-
MLB
1 stop4h 05m
Delta
Deal found 1/27$327
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:56 pm
MLB
-
CHS
1 stop5h 11m
American Airlines
Sat 2/147:03 pm
CHS
-
MLB
1 stop4h 48m
American Airlines
Deal found 1/26$328
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:19 am
MLB
-
CLT
Nonstop2h 01m
American Airlines
Mon 3/99:23 am
CLT
-
MLB
Nonstop1h 59m
American Airlines
Deal found 1/26$335
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2412:30 pm
MLB
-
CLT
Nonstop1h 59m
American Airlines
Tue 3/39:29 am
CLT
-
MLB
Nonstop1h 59m
American Airlines
Deal found 1/27$340
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:35 pm
MLB
-
CLT
1 stop5h 22m
Delta
Wed 6/105:30 am
CLT
-
MLB
1 stop5h 04m
Delta
Deal found 1/27$351
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1311:20 am
MLB
-
MYR
1 stop3h 37m
Delta
Wed 5/201:05 pm
MYR
-
MLB
1 stop4h 55m
Delta
Deal found 1/26$353
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:00 am
MLB
-
CLT
1 stop4h 23m
Delta
Mon 3/95:30 am
CLT
-
MLB
1 stop5h 10m
Delta
Deal found 1/26$355
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:02 pm
MLB
-
CLT
Nonstop2h 02m
American Airlines
Mon 3/1610:06 pm
CLT
-
MLB
Nonstop1h 45m
American Airlines
Deal found 1/27$359
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:55 am
MLB
-
GSP
1 stop3h 32m
Delta
Sat 6/276:45 am
GSP
-
MLB
1 stop3h 49m
Delta
Deal found 1/26$363
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/275:56 pm
MLB
-
CLT
Nonstop1h 57m
American Airlines
Tue 2/33:35 pm
CLT
-
MLB
Nonstop1h 51m
American Airlines
Deal found 1/26$369

Find flight deals from Melbourne to South Carolina

Keep the following information in mind while searching for Melbourne to South Carolina flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$293
(Delta)

One-way from

$147
(Kiwi.com)

Popular in

August

Cheapest in

February

Average price

$125
Provider with most accurate pricing for Orlando (ORL)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Orlando (ORL)-Myrtle Beach Intl flights.
Search Deals
From Melbourne to South Carolina
Search Deals
One-way flight from Melbourne to South Carolina
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Melbourne to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Melbourne to South Carolina that are best for you.

Fly from

Melbourne

Fly to

South Carolina

Route

Depart

Return

Price

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

Tue 3/3

6:43 pm-11:54 pm

1 stop5h 11m

Charleston

Sat 3/7

1:26 pm-5:48 pm

1 stop4h 22m

$293

MelbourneGreenville

MLB - GSP

MLBGSP

Melbourne

Wed 4/1

6:00 am-11:05 am

1 stop5h 05m

Greenville

Sat 4/11

5:38 pm-9:41 pm

1 stop4h 03m

$317

MelbourneColumbia

MLB - CAE

MLBCAE

Melbourne

Thu 2/26

6:00 am-9:28 am

1 stop3h 28m

Columbia Metropolitan

Thu 3/5

6:50 pm-10:55 pm

1 stop4h 05m

$327

MelbourneCharleston

MLB - CHS

MLBCHS

Melbourne

Tue 2/10

5:56 pm-11:07 pm

1 stop5h 11m

Charleston

Sat 2/14

7:03 pm-11:51 pm

1 stop4h 48m

$328

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Sat 6/6

6:00 am-8:01 am

Nonstop2h 01m

Charlotte Douglas

Wed 6/10

3:24 pm-5:11 pm

Nonstop1h 47m

$335

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Tue 2/24

12:30 pm-2:29 pm

Nonstop1h 59m

Charlotte Douglas

Tue 3/3

9:29 am-11:28 am

Nonstop1h 59m

$340

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Sat 6/6

6:35 pm-11:57 pm

1 stop5h 22m

Charlotte Douglas

Wed 6/10

5:30 am-10:34 am

1 stop5h 04m

$351

MelbourneMyrtle Beach

MLB - MYR

MLBMYR

Melbourne

Wed 5/13

11:20 am-2:57 pm

1 stop3h 37m

Myrtle Beach Intl

Wed 5/20

1:05 pm-6:00 pm

1 stop4h 55m

$353

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Sat 3/7

6:00 am-10:23 am

1 stop4h 23m

Charlotte Douglas

Mon 3/9

5:30 am-10:40 am

1 stop5h 10m

$355

MelbourneCharlotte

MLB - CLT

MLBCLT

Melbourne

Fri 5/29

6:00 am-8:01 am

Nonstop2h 01m

Charlotte Douglas

Mon 6/1

9:16 am-11:10 am

Nonstop1h 54m

$359

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 52 results
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Best time to book a flight from Melbourne to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Melbourne with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Melbourne to South Carolina

What is the cheapest month to book a flight from Melbourne, Florida to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Melbourne, Florida to South Carolina (average of $41). Flying from Melbourne, Florida to South Carolina in January is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 28, 2026.
Read through reviews of airlines operating flights from Melbourne to South Carolina, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,123 reviews

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,123 reviews
Delta
7.9
Good
8,123 reviews

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,201 reviews
Delta
7.9
Good
8,123 reviews

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Melbourne to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Melbourne to South Carolina?

    Located just 2.7 mi from the city center, Melbourne (MLB) is the airport most travelers will use when flying to South Carolina from Melbourne.

  • How long is the flight from Melbourne, Florida to South Carolina?

    A quick flight from Melbourne, Florida to South Carolina can take about 5h 11m. Delta provides one of the quickest options available for as low as $293. There are 333 mi between Melbourne, Florida and South Carolina.

  • What are the most popular routes from Melbourne, Florida to South Carolina?

    While some choose either Melbourne - Greenville or Melbourne - Columbia Metropolitan, Melbourne - Charlotte Douglas is the most popular route from Melbourne, Florida to South Carolina.

  • Can I find deals for flights from Melbourne to South Carolina that include hotel bookings?

    Yes. In addition to deals on Melbourne to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Melbourne to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Melbourne to South Carolina.

  • Can I find deals for business class flights from Melbourne to South Carolina?

    Yes. Cheapflights offers flight deals from Melbourne to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Melbourne, Florida to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Melbourne, Florida to South Carolina (average of $41). Flying from Melbourne, Florida to South Carolina in January is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Melbourne to South Carolina

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Top 2 airlines flying from Melbourne to South Carolina

Discover the top 2 airlines that operate flights from Melbourne to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$276Average$377FlexibilityNo cancel feeOn-time71%
DeltaCheapest$297Average$336FlexibilityNo cancel feeOn-timeN/A

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