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South Carolina

$634+ Cheap flights from Luxembourg to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
LUX — CHS
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Luxembourg to South Carolina

Cheapest flights from Luxembourg to South Carolina
Explore the most affordable flight options available from Luxembourg to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:30 amLUX - CLT
2 stops21h 38mMultiple Airlines
Mon 11/175:45 amCLT - LUX
3 stops22h 50mMultiple Airlines
Deal found 10/28$634
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2211:20 amLUX - CLT
1 stop13h 35mAmerican Airlines
Tue 11/258:20 pmCLT - LUX
1 stop12h 40mAmerican Airlines
Deal found 10/27$654
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:55 pmLUX - CLT
1 stop22h 10mAmerican Airlines
Mon 11/1711:05 pmCLT - LUX
1 stop16h 00mAmerican Airlines
Deal found 10/28$656
This Lufthansa deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/222:20 pmLUX - CLT
2 stops15h 38mLufthansa
Tue 11/255:35 pmCLT - LUX
2 stops16h 45mLufthansa
Deal found 10/26$688
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:30 amLUX - CLT
2 stops15h 21mUnited Airlines
Mon 11/177:44 pmCLT - LUX
2 stops14h 36mUnited Airlines
Deal found 10/28$689
This Lufthansa deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/277:55 pmLUX - CLT
1 stop27h 00mLufthansa
Thu 12/47:49 pmCLT - LUX
2 stops12h 06mLufthansa
Deal found 10/28$700
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2211:20 amLUX - GSP
2 stops16h 22mAmerican Airlines
Tue 11/2512:07 pmGSP - LUX
2 stops20h 53mAmerican Airlines
Deal found 10/27$727
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2210:55 amLUX - GSP
2 stops16h 00mDelta
Tue 11/251:58 pmGSP - LUX
2 stops14h 27mDelta
Deal found 10/26$758

Cheap flight deals from Luxembourg to South Carolina

Keep the following information in mind while searching for Luxembourg to South Carolina flight deals. Data was last updated October 29, 2025.

Round-trip from

$634
(Mytrip)
From Luxembourg to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Luxembourg to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Luxembourg to South Carolina that are best for you.

Fly from

Luxembourg

Fly to

South Carolina

Route

Depart

Return

Price

LuxembourgCharlotte

LUX - CLT

LUXCLT

Luxembourg

Thu 11/13

7:30 am-11:08 pm

2 stops21h 38m

Charlotte Douglas

Mon 11/17

5:45 am-10:35 am

3 stops22h 50m

$634

LuxembourgCharlotte

LUX - CLT

LUXCLT

Luxembourg

Sat 11/22

11:20 am-6:55 pm

1 stop13h 35m

Charlotte Douglas

Tue 11/25

8:20 pm-3:00 pm

1 stop12h 40m

$654

LuxembourgCharlotte

LUX - CLT

LUXCLT

Luxembourg

Thu 11/13

11:00 am-6:55 pm

1 stop13h 55m

Charlotte Douglas

Mon 11/17

6:33 pm-9:05 pm

2 stops20h 32m

$656

LuxembourgCharlotte

LUX - CLT

LUXCLT

Luxembourg

Thu 11/27

6:00 am-6:05 pm

2 stops18h 05m

Charlotte Douglas

Thu 12/4

10:00 am-10:25 am

2 stops18h 25m

$669

LuxembourgCharlotte

LUX - CLT

LUXCLT

Luxembourg

Sat 11/22

2:20 pm-11:58 pm

2 stops15h 38m

Charlotte Douglas

Tue 11/25

5:35 pm-4:20 pm

2 stops16h 45m

$688

LuxembourgCharlotte

LUX - CLT

LUXCLT

Luxembourg

Thu 11/13

9:30 am-6:51 pm

2 stops15h 21m

Charlotte Douglas

Mon 11/17

7:44 pm-4:20 pm

2 stops14h 36m

$689

LuxembourgGreenville

LUX - GSP

LUXGSP

Luxembourg

Sat 11/22

11:20 am-9:42 pm

2 stops16h 22m

Greenville

Tue 11/25

12:07 pm-3:00 pm

2 stops20h 53m

$727

LuxembourgMyrtle Beach

LUX - MYR

LUXMYR

Luxembourg

Fri 2/20

11:00 am-10:28 pm

2 stops17h 28m

Myrtle Beach Intl

Tue 2/24

5:38 pm-9:10 pm

2 stops21h 32m

$727

LuxembourgGreenville

LUX - GSP

LUXGSP

Luxembourg

Sat 11/22

10:55 am-8:55 pm

2 stops16h 00m

Greenville

Tue 11/25

1:58 pm-10:25 am

2 stops14h 27m

$758

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Best time to book a flight from Luxembourg to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Luxembourg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Luxembourg to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 29, 2025.
Read through reviews of airlines operating flights from Luxembourg to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,030 reviews

Boarding

7.5

Overall

7.2

Entertainment

6.9

Crew

8.0

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Nordia,Sep 2025

KIN - MIA

We were to land in Miami sometime after 3pm but couldn’t due to bad weather, we flew around for 2 hrs until we had to land in Forth Myers to refuel, we had to sit another 2 hrs at Forth Myers until given the clearance to refuel, we were hungry, thirsty and frustrated at that point. All the had on the flight to offer was a small plastic glass of water and a pack of biscoff, I requested a cup of tea and was told none was there. We were basically at another airport and not one of the staff could consider that the passengers might be hungry or thirsty being on a plane for around 8 hrs, which you weren’t prepared for, at least find some hot water on board.
American Airlines
7.2
Good
11,030 reviews
American Airlines
7.2
Good
11,030 reviews

Boarding

7.5

Overall

7.2

Entertainment

6.9

Crew

8.0

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Nordia,Sep 2025

KIN - MIA

We were to land in Miami sometime after 3pm but couldn’t due to bad weather, we flew around for 2 hrs until we had to land in Forth Myers to refuel, we had to sit another 2 hrs at Forth Myers until given the clearance to refuel, we were hungry, thirsty and frustrated at that point. All the had on the flight to offer was a small plastic glass of water and a pack of biscoff, I requested a cup of tea and was told none was there. We were basically at another airport and not one of the staff could consider that the passengers might be hungry or thirsty being on a plane for around 8 hrs, which you weren’t prepared for, at least find some hot water on board.

Related info for your journey

Find useful and relevant information for your journey from Luxembourg to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Luxembourg to South Carolina?

    A quick flight from Luxembourg to South Carolina can take about 13h 35m. American Airlines provides one of the quickest options available for as low as $654. The distance from Luxembourg to South Carolina is about 4298 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Luxembourg to South Carolina that include hotel bookings?

    Yes. In addition to deals on Luxembourg to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Luxembourg to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Luxembourg to South Carolina.

  • Can I find deals for business class flights from Luxembourg to South Carolina?

    Yes. Cheapflights offers flight deals from Luxembourg to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Luxembourg to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Luxembourg to South Carolina

Discover the top airline that operate flights from Luxembourg to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$504Average$646FlexibilityNo cancel feeOn-time71%

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