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South Carolina

$119+ Cheap flights from Key West (EYW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Key West to South Carolina

Keep the following information in mind while searching for Key West to South Carolina flight deals. Data was last updated junio 12, 2025.

Round-trip from

$339
(Mytrip)

One-way from

$119
(Expedia)
From Key West to South Carolina
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One-way flight from Key West to South Carolina
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Find flight deals from Key West to South Carolina

Cheapest flights from Key West to South Carolina
Explore the most affordable flight options available from Key West to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/410:23 amEYW - CLT
2 stops30h 34mMultiple Airlines
dom. 7/1311:40 amCLT - EYW
2 stops28h 56mMultiple Airlines
Deal found 6/10$339
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/277:00 amEYW - AGS
1 stop6h 38mDelta
lun. 9/15:45 amAGS - EYW
1 stop5h 11mDelta
Deal found 6/10$359
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/275:55 pmEYW - AGS
1 stop5h 09mAmerican Airlines
lun. 9/19:52 amAGS - EYW
2 stops9h 15mAmerican Airlines
Deal found 6/12$364
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 6/268:53 amEYW - SAV
2 stops14h 46mMultiple Airlines
lun. 6/3012:02 pmSAV - EYW
2 stops21h 20mMultiple Airlines
Deal found 6/10$409
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/102:35 pmEYW - SAV
1 stop4h 09mDelta
lun. 10/132:24 pmSAV - EYW
1 stop5h 20mDelta
Deal found 6/10$427
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/57:51 pmEYW - SAV
1 stop4h 28mAmerican Airlines
sáb. 7/126:00 amSAV - EYW
1 stop4h 57mAmerican Airlines
Deal found 6/9$443
This Mytrip deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/53:58 pmEYW - SAV
2 stops31h 39mAllegiant Air
sáb. 7/129:08 amSAV - EYW
1 stop26h 33mAllegiant Air
Deal found 6/9$465
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/412:39 pmEYW - CLT
Nonstop2h 20mAmerican Airlines
dom. 7/2010:36 pmCLT - EYW
1 stop12h 55mAmerican Airlines
Deal found 6/12$476
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/47:10 amEYW - CLT
1 stop3h 58mDelta
dom. 7/136:52 amCLT - EYW
1 stop3h 59mDelta
Deal found 6/10$504
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/216:45 pmEYW - CLT
2 stops19h 22mUnited Airlines
vie. 7/257:40 pmCLT - EYW
2 stops12h 20mUnited Airlines
Deal found 6/10$518
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/202:05 pmEYW - CHS
1 stop6h 41mDelta
lun. 6/236:20 amCHS - EYW
1 stop6h 49mDelta
Deal found 6/12$607
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/203:02 pmEYW - CHS
1 stop6h 52mAmerican Airlines
lun. 6/235:00 amCHS - EYW
2 stops5h 50mAmerican Airlines
Deal found 6/10$612

Cheapflights Fare Finder

Customize your flight search to find flights from Key West to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Key West to South Carolina that are best for you.

Fly from

Key West

Fly to

South Carolina

Route

Depart

Return

Price

Key WestCharlotte

EYW - CLT

EYWCLT

Key West

vie. 7/4

10:23 am-4:57 pm

2 stops30h 34m

Charlotte Douglas

dom. 7/13

11:40 am-4:36 pm

2 stops28h 56m

$339

Key WestAugusta

EYW - AGS

EYWAGS

Key West

mié. 8/27

7:00 am-1:38 pm

1 stop6h 38m

Augusta Bush Field

lun. 9/1

5:45 am-10:56 am

1 stop5h 11m

$359

Key WestAugusta

EYW - AGS

EYWAGS

Key West

mié. 8/27

5:55 pm-11:04 pm

1 stop5h 09m

Augusta Bush Field

lun. 9/1

9:52 am-7:07 pm

2 stops9h 15m

$364

Key WestSavannah

EYW - SAV

EYWSAV

Key West

jue. 6/26

8:53 am-11:39 pm

2 stops14h 46m

Savannah/Hilton Head

lun. 6/30

12:02 pm-9:22 am

2 stops21h 20m

$409

Key WestSavannah

EYW - SAV

EYWSAV

Key West

sáb. 7/5

7:51 pm-12:19 am

1 stop4h 28m

Savannah/Hilton Head

sáb. 7/12

6:00 am-10:57 am

1 stop4h 57m

$443

Key WestSavannah

EYW - SAV

EYWSAV

Key West

sáb. 7/5

3:58 pm-11:37 pm

2 stops31h 39m

Savannah/Hilton Head

sáb. 7/12

9:08 am-11:41 am

1 stop26h 33m

$465

Key WestCharlotte

EYW - CLT

EYWCLT

Key West

vie. 7/4

12:39 pm-2:59 pm

Nonstop2h 20m

Charlotte Douglas

dom. 7/20

10:36 pm-11:31 am

1 stop12h 55m

$476

Key WestSavannah

EYW - SAV

EYWSAV

Key West

jue. 6/26

2:05 pm-7:14 pm

1 stop5h 09m

Savannah/Hilton Head

lun. 6/30

11:59 am-5:34 pm

1 stop5h 35m

$487

Key WestCharlotte

EYW - CLT

EYWCLT

Key West

vie. 7/4

7:10 am-11:08 am

1 stop3h 58m

Charlotte Douglas

dom. 7/13

6:52 am-10:51 am

1 stop3h 59m

$504

Key WestCharlotte

EYW - CLT

EYWCLT

Key West

lun. 7/21

6:45 pm-2:07 pm

2 stops19h 22m

Charlotte Douglas

vie. 7/25

7:40 pm-8:00 am

2 stops12h 20m

$518

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 17 results
1
2

Best time to book a flight from Key West to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to South Carolina

What is the cheapest time of day to fly from EYW to SC?

Find hourly flight availability from Key West to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

When flying from Key West to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated junio 12, 2025.
Read through reviews of airlines operating flights from Key West to South Carolina, such as Breeze Airways, Delta and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
178 reviews

Food

6.7

Boarding

8.3

Entertainment

6.6

Overall

8.1

Comfort

8.2

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Breeze Airways
8.1
Very good
178 reviews
Breeze Airways
8.1
Very good
178 reviews

Food

6.7

Boarding

8.3

Entertainment

6.6

Overall

8.1

Comfort

8.2

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Delta
8.0
Very good
7,950 reviews
Breeze Airways
8.1
Very good
178 reviews

Food

6.7

Boarding

8.3

Entertainment

6.6

Overall

8.1

Comfort

8.2

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
United Airlines
7.4
Good
8,790 reviews
Breeze Airways
8.1
Very good
178 reviews

Food

6.7

Boarding

8.3

Entertainment

6.6

Overall

8.1

Comfort

8.2

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Allegiant Air
7.3
Good
725 reviews
Breeze Airways
8.1
Very good
178 reviews

Food

6.7

Boarding

8.3

Entertainment

6.6

Overall

8.1

Comfort

8.2

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
American Airlines
7.2
Good
10,000 reviews
Breeze Airways
8.1
Very good
178 reviews

Food

6.7

Boarding

8.3

Entertainment

6.6

Overall

8.1

Comfort

8.2

Crew

8.8

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Key West to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Key West to South Carolina?

    For a flight from Key West to South Carolina, you will be flying from Key West. Key West (EYW) is just 2.6 mi from the center of the city.

  • What are the cheapest airlines to fly from Key West to South Carolina one-way?

    To fly one-way, consider booking your trip with Breeze Airways, which is currently one of the cheapest options available, starting at $119. American Airlines flights start at $220 while deals on United Airlines start at $230 one-way.

  • What are the most popular routes from Key West to South Carolina?

    When deciding which route to take from Key West to South Carolina consider Key West - Charlotte Douglas, Key West - Augusta Bush Field or Key West - Charleston as they are the most popular.

  • Can I find deals for flights from Key West to South Carolina that include hotel bookings?

    Yes. In addition to deals on Key West to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to South Carolina.

  • Can I find deals for business class flights from Key West to South Carolina?

    Yes. Cheapflights offers flight deals from Key West to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key West to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Key West to South Carolina (average of $217). Flying from Key West to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Key West to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Key West to South Carolina

Discover the top airline that operate flights from Key West to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$293Average$635FlexibilityNo cancel feeOn-time71%

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