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South Carolina

$85+ Cheap flights from Key West (EYW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Key West to South Carolina

Keep the following information in mind while searching for Key West to South Carolina flight deals. Data was last updated July 30, 2025.

Round-trip from

$172
(Kiwi.com)

One-way from

$85
(Kiwi.com)
From Key West to South Carolina
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One-way flight from Key West to South Carolina
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Find flight deals from Key West to South Carolina

Cheapest flights from Key West to South Carolina
Explore the most affordable flight options available from Key West to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/141:47 pmEYW - CHS
1 stop24h 45mBreeze Airways
Mon 8/189:31 pmCHS - EYW
1 stop11h 51mBreeze Airways
Deal found 7/30$172
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/277:00 amEYW - CHS
1 stop5h 14mDelta
Tue 12/22:25 pmCHS - EYW
1 stop5h 19mDelta
Deal found 7/29$287
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/277:00 amEYW - AGS
1 stop6h 38mDelta
Mon 9/13:30 pmAGS - EYW
1 stop4h 42mDelta
Deal found 7/28$319
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/271:13 pmEYW - AGS
1 stop7h 21mAmerican Airlines
Mon 9/15:00 amAGS - EYW
2 stops7h 58mAmerican Airlines
Deal found 7/28$324
This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/249:47 amEYW - CLT
2 stops23h 35mMultiple Airlines
Fri 9/261:14 pmCLT - EYW
1 stop7h 27mMultiple Airlines
Deal found 7/28$336
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/278:12 amEYW - CHS
1 stop4h 04mAmerican Airlines
Tue 12/25:10 amCHS - EYW
2 stops5h 58mAmerican Airlines
Deal found 7/29$354
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/236:22 pmEYW - SAV
1 stop5h 37mDelta
Tue 8/268:20 amSAV - EYW
1 stop4h 45mDelta
Deal found 7/27$357
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/235:56 pmEYW - SAV
1 stop6h 03mAmerican Airlines
Wed 8/276:15 amSAV - EYW
2 stops6h 57mAmerican Airlines
Deal found 7/30$372
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1512:10 pmEYW - CLT
1 stop19h 50mAmerican Airlines
Sat 8/2310:34 pmCLT - EYW
1 stop13h 06mAmerican Airlines
Deal found 7/28$462
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/291:47 pmEYW - CHS
3 stops28h 59mMultiple Airlines
Sun 8/3110:38 amCHS - EYW
2 stops22h 44mMultiple Airlines
Deal found 7/29$474
This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/48:55 amEYW - SAV
2 stops26h 12mMultiple Airlines
Sun 9/712:02 pmSAV - EYW
3 stops23h 50mMultiple Airlines
Deal found 7/28$507
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/122:22 pmEYW - CLT
1 stop8h 20mUnited Airlines
Sat 8/166:00 amCLT - EYW
2 stops30h 41mUnited Airlines
Deal found 7/28$618

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Key West to South Carolina that are best for you.

Fly from

Key West

Fly to

South Carolina

Route

Depart

Return

Price

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 8/14

1:47 pm-2:32 pm

1 stop24h 45m

Charleston

Mon 8/18

9:31 pm-9:22 am

1 stop11h 51m

$172

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 11/27

7:00 am-12:14 pm

1 stop5h 14m

Charleston

Tue 12/2

2:25 pm-7:44 pm

1 stop5h 19m

$287

Key WestAugusta

EYW - AGS

EYWAGS

Key West

Wed 8/27

7:00 am-11:24 am

1 stop4h 24m

Augusta Bush Field

Mon 9/1

5:45 am-10:56 am

1 stop5h 11m

$319

Key WestAugusta

EYW - AGS

EYWAGS

Key West

Wed 8/27

1:13 pm-7:04 pm

1 stop5h 51m

Augusta Bush Field

Mon 9/1

5:00 am-12:58 pm

2 stops7h 58m

$324

Key WestCharlotte

EYW - CLT

EYWCLT

Key West

Wed 9/24

9:47 am-9:22 am

2 stops23h 35m

Charlotte Douglas

Fri 9/26

1:14 pm-8:41 pm

1 stop7h 27m

$336

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 11/27

8:12 am-12:16 pm

1 stop4h 04m

Charleston

Tue 12/2

5:10 am-11:08 am

2 stops5h 58m

$354

Key WestSavannah

EYW - SAV

EYWSAV

Key West

Sat 8/23

6:22 pm-11:59 pm

1 stop5h 37m

Savannah/Hilton Head

Tue 8/26

8:20 am-1:05 pm

1 stop4h 45m

$357

Key WestSavannah

EYW - SAV

EYWSAV

Key West

Sat 8/23

5:56 pm-11:59 pm

1 stop6h 03m

Savannah/Hilton Head

Wed 8/27

6:15 am-1:12 pm

2 stops6h 57m

$372

Key WestCharlotte

EYW - CLT

EYWCLT

Key West

Fri 8/15

12:10 pm-8:00 am

1 stop19h 50m

Charlotte Douglas

Sat 8/23

10:34 pm-11:40 am

1 stop13h 06m

$462

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Fri 8/29

1:47 pm-6:46 pm

3 stops28h 59m

Charleston

Sun 8/31

10:38 am-9:22 am

2 stops22h 44m

$474

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 25 results
1
2
3

Best time to book a flight from Key West to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to South Carolina

What is the cheapest time of day to fly from EYW to SC?

Find hourly flight availability from Key West to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

When flying from Key West to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 30, 2025.
Read through reviews of airlines operating flights from Key West to South Carolina, such as Delta, Breeze Airways, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Entertainment

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Entertainment

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Breeze Airways
8.0
Very good
191 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Entertainment

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Entertainment

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Entertainment

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Spirit Airlines
6.3
Okay
8,048 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Overall

8.0

Food

7.3

Entertainment

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Key West to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Key West to South Carolina?

    For a flight from Key West to South Carolina, you will be flying from Key West. Key West (EYW) is just 2.6 mi from the center of the city.

  • What are the cheapest airlines to fly from Key West to South Carolina one-way?

    To fly one-way, consider booking your trip with Breeze Airways, which is currently one of the cheapest options available, starting at $85. Spirit Airlines flights start at $123 while deals on Delta start at $214 one-way.

  • What are the most popular routes from Key West to South Carolina?

    When deciding which route to take from Key West to South Carolina consider Key West - Charlotte Douglas, Key West - Charleston or Key West - Savannah/Hilton Head as they are the most popular.

  • Can I find deals for flights from Key West to South Carolina that include hotel bookings?

    Yes. In addition to deals on Key West to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to South Carolina.

  • Can I find deals for business class flights from Key West to South Carolina?

    Yes. Cheapflights offers flight deals from Key West to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key West to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Key West to South Carolina (average of $217). Flying from Key West to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Key West to South Carolina

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Top 2 airlines flying from Key West to South Carolina

Discover the top 2 airlines that operate flights from Key West to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$313FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$323Average$615FlexibilityNo cancel feeOn-time71%

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