$359+ Cheap flights from Ithaca (ITH) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
ITH — CHS
Nov 18 — Nov 251
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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Cheapest flights from Ithaca to South CarolinaExplore the most affordable flight options available from Ithaca to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from Ithaca to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:45 am -
1 stop6h 27m
Wed 11/116:00 am -
1 stop6h 13m
Deal found 10/15![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:45 am -
2 stops7h 33m
Tue 11/105:19 pm -
1 stop5h 04m
Deal found 10/15![Delta logo]()
$364
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:45 am -
2 stops7h 28m
Tue 11/105:19 pm -
1 stop5h 04m
Deal found 10/15![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop4h 06m
Tue 11/37:52 pm -
1 stop3h 52m
Deal found 10/15![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:45 am -
2 stops9h 30m
Tue 11/35:40 pm -
1 stop4h 49m
Deal found 10/15![Delta logo]()
$394
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 am -
2 stops29h 22m
Wed 11/116:00 am -
1 stop6h 13m
Deal found 10/15![Delta logo]()
$428
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:45 am -
2 stops7h 33m
Sat 11/76:29 pm -
2 stops17h 54m
Deal found 10/15![Delta logo]()
$433
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:45 am -
2 stops7h 28m
Fri 11/612:57 pm -
1 stop23h 26m
Deal found 10/15![Delta logo]()
$493
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 am -
2 stops29h 22m
Tue 11/106:34 am -
2 stops29h 39m
Deal found 10/15![Delta logo]()
$497
Best flights from Ithaca to South CarolinaDiscover carefully curated flight deals from Ithaca to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from Ithaca to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:45 am -
1 stop6h 27m
Sat 11/76:05 am -
1 stop6h 18m
Deal found 10/19![Delta logo]()
$389
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop4h 06m
Tue 11/37:52 pm -
1 stop3h 52m
Deal found 10/15![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:45 am -
2 stops9h 30m
Tue 11/35:40 pm -
1 stop4h 49m
Deal found 10/15![Delta logo]()
$394
This Delta deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/205:55 am -
2 stops8h 15m
Thu 2/255:40 am -
2 stops7h 35m
Deal found 10/16![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
2 stops7h 22m
Wed 11/47:52 pm -
1 stop3h 52m
Deal found 10/16![United Airlines logo]()
$524
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/89:45 am -
1 stop4h 39m
Tue 1/122:59 pm -
1 stop3h 41m
Deal found 10/14![United Airlines logo]()
$592
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/206:00 am -
2 stops7h 52m
Wed 2/242:30 pm -
2 stops9h 00m
Deal found 10/16![United Airlines logo]()
$602
This United Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/89:45 am -
1 stop5h 28m
Mon 1/117:51 pm -
1 stop3h 53m
Deal found 10/17![United Airlines logo]()
$668
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:45 am -
2 stops7h 28m
Thu 11/55:40 pm -
1 stop4h 49m
Deal found 10/15![Delta logo]()
$741
Last-minute flights from Ithaca to South CarolinaDiscover last-minute flight deals from Ithaca to South Carolina. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from Ithaca to South Carolina. Data last updated October 19, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
1 stop4h 06m
Tue 11/37:52 pm -
1 stop3h 52m
Deal found 10/15![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:45 am -
2 stops9h 30m
Tue 11/35:40 pm -
1 stop4h 49m
Deal found 10/15![Delta logo]()
$394
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:45 am -
2 stops7h 28m
Sat 11/76:05 am -
1 stop6h 18m
Deal found 10/15![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:45 am -
1 stop6h 27m
Tue 11/106:00 am -
1 stop6h 13m
Deal found 10/15![Delta logo]()
$404
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:45 am -
2 stops7h 28m
Fri 11/612:57 pm -
1 stop23h 26m
Deal found 10/15![Delta logo]()
$493
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 am -
2 stops29h 22m
Wed 11/116:00 am -
1 stop6h 13m
Deal found 10/15![Delta logo]()
$428
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 am -
2 stops29h 22m
Tue 11/106:34 am -
2 stops29h 39m
Deal found 10/15![Delta logo]()
$497
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:45 am -
1 stop6h 27m
Tue 11/105:19 pm -
1 stop5h 04m
Deal found 10/15![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:45 am -
2 stops7h 33m
Sat 11/76:29 pm -
2 stops17h 54m
Deal found 10/15![Delta logo]()
$433
Find flight deals from Ithaca to South Carolina
Keep the following information in mind while searching for Ithaca to South Carolina flight deals. Data was last updated October 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $359 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Ithaca to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from Ithaca to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IthacaCharleston
ITH Ithaca Tompkins County - CHS Charleston
ITHCHS
Ithaca Tompkins County
Tue 11/3
5:45 am-12:12 pm
1 stop6h 27m
Charleston
Sat 11/7
6:05 am-12:23 pm
1 stop6h 18m
$389
Quickest round-trip
IthacaCharleston
ITH Ithaca Tompkins County - CHS Charleston
ITHCHS
Ithaca Tompkins County
Fri 10/30
6:00 am-10:06 am
1 stop4h 06m
Charleston
Tue 11/3
7:52 pm-11:44 pm
1 stop3h 52m
$389
IthacaCharleston
ITH Ithaca Tompkins County - CHS Charleston
ITHCHS
Ithaca Tompkins County
Fri 10/30
5:45 am-3:15 pm
2 stops9h 30m
Charleston
Tue 11/3
5:40 pm-10:29 pm
1 stop4h 49m
$394
IthacaColumbia
ITH Ithaca Tompkins County - CAE Columbia Metropolitan
ITHCAE
Ithaca Tompkins County
Sat 2/20
5:55 am-2:10 pm
2 stops8h 15m
Columbia Metropolitan
Thu 2/25
5:40 am-1:15 pm
2 stops7h 35m
$409
IthacaCharleston
ITH Ithaca Tompkins County - CHS Charleston
ITHCHS
Ithaca Tompkins County
Sat 10/31
6:00 am-1:22 pm
2 stops7h 22m
Charleston
Wed 11/4
7:52 pm-11:44 pm
1 stop3h 52m
$524
IthacaColumbia
ITH Ithaca Tompkins County - CAE Columbia Metropolitan
ITHCAE
Ithaca Tompkins County
Fri 1/8
9:45 am-2:24 pm
1 stop4h 39m
Columbia Metropolitan
Tue 1/12
2:59 pm-6:40 pm
1 stop3h 41m
$592
IthacaColumbia
ITH Ithaca Tompkins County - CAE Columbia Metropolitan
ITHCAE
Ithaca Tompkins County
Sat 2/20
6:00 am-1:52 pm
2 stops7h 52m
Columbia Metropolitan
Wed 2/24
2:30 pm-11:30 pm
2 stops9h 00m
$602
IthacaCharleston
ITH Ithaca Tompkins County - CHS Charleston
ITHCHS
Ithaca Tompkins County
Fri 1/8
9:45 am-3:13 pm
1 stop5h 28m
Charleston
Mon 1/11
7:51 pm-11:44 pm
1 stop3h 53m
$668
IthacaCharleston
ITH Ithaca Tompkins County - CHS Charleston
ITHCHS
Ithaca Tompkins County
Wed 11/4
5:45 am-1:13 pm
2 stops7h 28m
Charleston
Thu 11/5
5:40 pm-10:29 pm
1 stop4h 49m
$741
Sorted by cheapest first
Best time to book a flight from Ithaca to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Ithaca with our price prediction graph.
ITH-CHS
ITH-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Ithaca to South Carolina
ITH-USSC
ITH-CHS
ITH-CAE
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 19, 2026.
Peruse reviews from past customers who have flown with Delta from Ithaca to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Boarding
8.1
Food
7.2
Comfort
7.8
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Crew
8.5
Boarding
8.1
Food
7.2
Comfort
7.8
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
2.0
MediocreBarney,May 2026
JFK - ATL
Related info for your journey
Find useful and relevant information for your journey from Ithaca to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Ithaca to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Ithaca to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Ithaca and South Carolina flights
Browse other Ithaca and South Carolina flight options. Last updated on October 19, 2026.
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Ithaca to South Carolina flights
Consider these flights traveling from Ithaca to South Carolina.
Top airline flying from Ithaca to South Carolina
Discover the top airline that operate flights from Ithaca to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$217 | Average$441 | FlexibilityNo cancel fee | On-timeN/A |