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South Carolina

$131+ Cheap flights from Ithaca (ITH) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
ITH — CHS
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Cheap flight deals from Ithaca to South Carolina

Keep the following information in mind while searching for Ithaca to South Carolina flight deals. Data was last updated November 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$244
(Delta)

One-way from

$131
(Delta)
Provider with most accurate pricing for Ithaca Tompkins County-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Ithaca Tompkins County-Myrtle Beach Intl flights.
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From Ithaca Tompkins County to South Carolina
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One-way flight from Ithaca Tompkins County to South Carolina
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Find flight deals from Ithaca to South Carolina

Cheapest flights from Ithaca to South Carolina
Explore the most affordable flight options available from Ithaca to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/195:40 amITH - CLT
2 stops7h 50mDelta
Sun 11/236:00 amCLT - ITH
1 stop7h 09mDelta
Deal found 11/1$269
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/185:40 amITH - CLT
2 stops10h 44mDelta
Sat 11/226:00 amCLT - ITH
1 stop7h 09mDelta
Deal found 11/1$294
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:57 pmITH - CLT
1 stop4h 02mUnited Airlines
Mon 12/157:49 pmCLT - ITH
1 stop3h 54mUnited Airlines
Deal found 10/30$318
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:40 amITH - CAE
2 stops8h 28mDelta
Tue 11/1811:03 amCAE - ITH
2 stops11h 51mDelta
Deal found 11/2$319
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/172:05 pmITH - CLT
2 stops7h 46mDelta
Sat 11/226:00 amCLT - ITH
1 stop7h 09mDelta
Deal found 11/1$324
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/177:40 pmITH - CLT
1 stop4h 18mUnited Airlines
Sat 11/227:44 pmCLT - ITH
1 stop3h 59mUnited Airlines
Deal found 11/1$327
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:40 amITH - CAE
2 stops11h 14mDelta
Mon 11/175:37 amCAE - ITH
2 stops7h 32mDelta
Deal found 11/2$349
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:00 pmITH - CLT
2 stops9h 42mDelta
Mon 12/156:00 amCLT - ITH
1 stop7h 11mDelta
Deal found 10/30$349
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:40 amITH - CAE
2 stops8h 28mDelta
Tue 11/185:37 amCAE - ITH
2 stops7h 32mDelta
Deal found 11/2$369
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:40 amITH - CAE
2 stops8h 28mDelta
Mon 11/175:37 amCAE - ITH
2 stops7h 32mDelta
Deal found 11/2$399
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/186:10 amITH - CLT
2 stops7h 04mUnited Airlines
Sat 11/221:46 pmCLT - ITH
2 stops9h 57mUnited Airlines
Deal found 11/1$415
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/82:05 pmITH - CHS
1 stop6h 55mDelta
Sun 11/95:25 amCHS - ITH
2 stops7h 44mDelta
Deal found 11/2$449

Cheapflights Fare Finder

 
Customize your flight search to find flights from Ithaca to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Ithaca to South Carolina that are best for you.

Fly from

Ithaca

Fly to

South Carolina

Route

Depart

Return

Price

IthacaSavannah

ITH - SAV

ITHSAV

Ithaca Tompkins County

Tue 2/24

2:00 pm-9:28 pm

1 stop7h 28m

Savannah/Hilton Head

Sat 2/28

7:25 am-1:19 pm

1 stop5h 54m

$244

IthacaCharleston

ITH - CHS

ITHCHS

Ithaca Tompkins County

Tue 3/3

5:55 am-11:52 am

1 stop5h 57m

Charleston

Sat 3/7

6:00 am-1:19 pm

1 stop7h 19m

$249

IthacaCharlotte

ITH - CLT

ITHCLT

Ithaca Tompkins County

Fri 1/23

5:25 am-4:04 pm

2 stops10h 39m

Charlotte Douglas

Sun 1/25

6:53 pm-11:22 pm

1 stop4h 29m

$254

IthacaGreenville

ITH - GSP

ITHGSP

Ithaca Tompkins County

Sat 2/21

2:00 pm-10:05 pm

2 stops8h 05m

Greenville

Wed 2/25

6:45 am-1:19 pm

2 stops6h 34m

$259

IthacaCharleston

ITH - CHS

ITHCHS

Ithaca Tompkins County

Mon 2/23

5:55 am-11:52 am

1 stop5h 57m

Charleston

Fri 2/27

6:00 am-1:19 pm

1 stop7h 19m

$261

IthacaCharlotte

ITH - CLT

ITHCLT

Ithaca Tompkins County

Wed 11/19

5:40 am-1:30 pm

2 stops7h 50m

Charlotte Douglas

Sun 11/23

6:00 am-1:09 pm

1 stop7h 09m

$269

IthacaCharlotte

ITH - CLT

ITHCLT

Ithaca Tompkins County

Tue 11/18

5:40 am-4:24 pm

2 stops10h 44m

Charlotte Douglas

Sat 11/22

6:00 am-1:09 pm

1 stop7h 09m

$294

IthacaCharlotte

ITH - CLT

ITHCLT

Ithaca Tompkins County

Fri 12/5

2:00 pm-9:55 pm

2 stops7h 55m

Charlotte Douglas

Sun 12/7

6:00 am-1:11 pm

1 stop7h 11m

$299

IthacaCharleston

ITH - CHS

ITHCHS

Ithaca Tompkins County

Mon 4/6

2:00 pm-11:39 pm

2 stops9h 39m

Charleston

Wed 4/8

5:25 pm-11:21 pm

1 stop5h 56m

$305

IthacaCharlotte

ITH - CLT

ITHCLT

Ithaca Tompkins County

Fri 1/23

6:00 am-10:03 am

1 stop4h 03m

Charlotte Douglas

Sun 1/25

7:44 pm-11:44 pm

1 stop4h 00m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 34 results
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Best time to book a flight from Ithaca to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Ithaca with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Ithaca to South Carolina

What is the cheapest month to book a flight from Ithaca to South Carolina?

Currently, April is the cheapest month in which you can book a flight from Ithaca to South Carolina (average of $47). Flying from Ithaca to South Carolina in August is currently the most expensive (average of $113). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ITH to SC?

Find hourly flight availability from Ithaca to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

It’s optimal to fly from Ithaca to South Carolina in the evening. By choosing this option you can save up to 69% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 3, 2025.
Peruse reviews from past customers who have flown with Delta and United Airlines from Ithaca to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Crew

8.5

Boarding

8.2

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Crew

8.5

Boarding

8.2

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,997 reviews
Delta
7.9
Good
8,001 reviews

Crew

8.5

Boarding

8.2

Overall

7.9

Comfort

7.9

Entertainment

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Ithaca to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Ithaca to South Carolina?

    Ithaca Tompkins County (ITH), located 4.0 mi from the city center, is the airport you fly out of when you book flights from Ithaca to South Carolina.

  • How long is the flight from Ithaca to South Carolina?

    A quick flight from Ithaca to South Carolina can take about 3h 49m. Delta provides one of the quickest options available for as low as $458. The distance between Ithaca and South Carolina is about 642 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Ithaca to South Carolina?

    While some choose either Ithaca Tompkins County - Charlotte Douglas or Ithaca Tompkins County - Myrtle Beach Intl, Ithaca Tompkins County - Charleston is the most popular route from Ithaca to South Carolina.

  • Can I find deals for flights from Ithaca to South Carolina that include hotel bookings?

    Yes. In addition to deals on Ithaca to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Ithaca to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Ithaca to South Carolina.

  • Can I find deals for business class flights from Ithaca to South Carolina?

    Yes. Cheapflights offers flight deals from Ithaca to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Ithaca to South Carolina?

    Currently, April is the cheapest month in which you can book a flight from Ithaca to South Carolina (average of $47). Flying from Ithaca to South Carolina in August is currently the most expensive (average of $113). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Ithaca to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Ithaca to South Carolina

Discover the top 2 airlines that operate flights from Ithaca to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$200Average$533FlexibilityNo cancel feeOn-time69%
DeltaCheapest$248Average$438FlexibilityNo cancel feeOn-timeN/A

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