South Carolina

$105+ Cheap flights from Irvine, CA to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/22. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — CHS
Jun 2 — Jun 91
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Irvine to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Irvine to South Carolina

Cheapest flights from Irvine to South Carolina
Explore the most affordable flight options available from Irvine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.

This Breeze Airways deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:00 pm
LAX
-
SAV
1 stop7h 47m
Breeze Airways
Mon 8/314:20 pm
SAV
-
LAX
1 stop8h 30m
Breeze Airways
Deal found 4/30$204
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/176:30 am
LAX
-
CLT
1 stop6h 55m
Frontier
Tue 5/268:55 am
CLT
-
LAX
1 stop13h 37m
Frontier
Deal found 4/28$267
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:45 am
LAX
-
CLT
1 stop7h 31m
Multiple Airlines
Mon 5/257:57 pm
CLT
-
LAX
2 stops39h 58m
Multiple Airlines
Deal found 4/28$269
This Frontier deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/198:41 am
LAX
-
CLT
1 stop12h 00m
Frontier
Sat 6/201:09 pm
CLT
-
LAX
1 stop12h 20m
Frontier
Deal found 4/28$270
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2811:00 pm
LAX
-
CLT
1 stop9h 34m
Frontier
Wed 7/110:14 pm
CLT
-
LAX
1 stop13h 19m
Frontier
Deal found 4/28$272
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:08 pm
LAX
-
CLT
1 stop15h 51m
Frontier
Mon 6/16:50 pm
CLT
-
LAX
2 stops17h 13m
Frontier
Deal found 4/28$273
This Frontier deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:45 am
LAX
-
CLT
1 stop7h 31m
Frontier
Sun 5/241:12 pm
CLT
-
LAX
1 stop8h 15m
Frontier
Deal found 5/1$275
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:30 am
LAX
-
CLT
1 stop6h 55m
Frontier
Thu 5/217:14 pm
CLT
-
LAX
1 stop8h 02m
Frontier
Deal found 4/30$276
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:30 am
LAX
-
CLT
1 stop8h 49m
Frontier
Sun 6/215:59 pm
CLT
-
LAX
1 stop16h 47m
Frontier
Deal found 5/1$277
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2711:00 pm
LAX
-
SAV
1 stop7h 47m
Multiple Airlines
Mon 8/314:20 pm
SAV
-
LAX
2 stops18h 19m
Multiple Airlines
Deal found 4/30$278
This Booking.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:30 am
LAX
-
CLT
1 stop6h 55m
Frontier
Fri 5/85:58 pm
CLT
-
LAX
1 stop27h 03m
Frontier
Deal found 4/29$278
This Frontier deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2012:49 am
LAX
-
CLT
1 stop13h 57m
Frontier
Sun 5/241:12 pm
CLT
-
LAX
1 stop8h 15m
Frontier
Deal found 5/1$280

Find flight deals from Irvine to South Carolina

Keep the following information in mind while searching for Irvine to South Carolina flight deals. Data was last updated May 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$204
(Breeze Airways)

One-way from

$105
(Frontier)

Popular in

December

Cheapest in

May

Average price

$408
Provider with most accurate pricing for Los Angeles-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Los Angeles-Myrtle Beach Intl flights.
From Irvine to South Carolina
One-way flight from Irvine to South Carolina
Highest demand for flights based on searches. 15% potential increase in price ($100 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from Irvine to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Los AngelesHilton Head Island

LAX - HHH

LAXHHH

Los Angeles

Tue 7/7

12:30 am-3:29 pm

2 stops11h 59m

Hilton Head Island

Mon 7/13

12:11 pm-11:53 pm

2 stops14h 42m

$358

Los AngelesColumbia

LAX - CAE

LAXCAE

Los Angeles

Wed 5/27

9:30 pm-9:56 am

1 stop9h 26m

Columbia Metropolitan

Wed 6/3

2:29 pm-7:16 pm

1 stop7h 47m

$369

Los AngelesColumbia

LAX - CAE

LAXCAE

Los Angeles

Fri 5/29

2:30 pm-11:47 pm

1 stop6h 17m

Columbia Metropolitan

Sun 5/31

7:17 pm-12:41 am

1 stop8h 24m

$369

Los AngelesCharleston

LAX - CHS

LAXCHS

Los Angeles

Wed 7/15

5:05 am-3:35 pm

1 stop7h 30m

Charleston

Wed 7/29

4:15 pm-7:45 pm

1 stop6h 30m

$379

Los AngelesCharleston

LAX - CHS

LAXCHS

Los Angeles

Fri 7/17

11:00 pm-10:51 am

1 stop8h 51m

Charleston

Tue 7/21

5:02 pm-9:50 pm

1 stop7h 48m

$381
Quickest round-trip

Los AngelesGreenville

LAX - GSP

LAXGSP

Los Angeles

Fri 5/22

12:54 pm-8:40 pm

Nonstop4h 46m

Greenville

Mon 5/25

10:03 am-12:09 pm

Nonstop5h 06m

$388

Los AngelesGreenville

LAX - GSP

LAXGSP

Los Angeles

Tue 6/2

5:00 am-4:20 pm

1 stop8h 20m

Greenville

Tue 6/9

12:50 pm-8:50 pm

2 stops11h 00m

$388

Los AngelesCharleston

LAX - CHS

LAXCHS

Los Angeles

Wed 5/6

12:23 pm-8:24 pm

Nonstop5h 01m

Charleston

Sat 5/9

9:13 am-11:38 am

Nonstop5h 25m

$388

Los AngelesMyrtle Beach

LAX - MYR

LAXMYR

Los Angeles

Thu 6/11

8:15 am-8:30 pm

1 stop9h 15m

Myrtle Beach Intl

Tue 6/16

7:15 pm-12:10 am

1 stop7h 55m

$389

Los AngelesGreenville

LAX - GSP

LAXGSP

Los Angeles

Wed 6/3

9:30 am-8:13 pm

1 stop7h 43m

Greenville

Fri 6/5

8:45 am-1:19 pm

1 stop7h 34m

$391

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/1

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Irvine to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to South Carolina

How much does it cost to fly round-trip from Irvine to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 3, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Irvine to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.6

Comfort

8.2

Crew

8.7

Boarding

8.3

Overall

8.1

Food

6.6

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Entertainment

6.6

Comfort

8.2

Crew

8.7

Boarding

8.3

Overall

8.1

Food

6.6

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Entertainment

6.6

Comfort

8.2

Crew

8.7

Boarding

8.3

Overall

8.1

Food

6.6

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Entertainment

6.6

Comfort

8.2

Crew

8.7

Boarding

8.3

Overall

8.1

Food

6.6

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Entertainment

6.6

Comfort

8.2

Crew

8.7

Boarding

8.3

Overall

8.1

Food

6.6

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Entertainment

6.6

Comfort

8.2

Crew

8.7

Boarding

8.3

Overall

8.1

Food

6.6

Reviews

1 / 18
4.0
Okay

Lisa,Mar 2026

ORF - JAX

*Flight was delayed twice *Once plane arrived crew closed the entryway to discuss whatever, leaving us to wait again. *Finally arriving Jax, we were delayed again for 20 minutes because another plane at the gate hadn’t pushed back Overall, score 2 out of 5. Lots of passengers upset.

Related info for your journey

Find useful and relevant information for your journey from Irvine to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this Irvine to South Carolina flight route?

  • How long is the flight from Irvine to South Carolina?

    There are many flights that can get you from Irvine to South Carolina in 7h 30m. Fly via Delta, United Airlines, or Southwest to get the fastest option. The distance between Irvine and South Carolina is about 2200 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Irvine to South Carolina one-way?

    To fly one-way, consider booking your trip with Breeze Airways, which is currently one of the cheapest options available, starting at $89. Spirit Airlines flights start at $94 while deals on JetBlue start at $126 one-way.

  • What are the most popular routes from Irvine to South Carolina?

  • What are the cheapest flights from Irvine to South Carolina?

    The cheapest flight price from Irvine to South Carolina is $142. On average you can expect to pay $278. The most popular route, (Los Angeles - Charlotte Douglas), can usually be booked for $224.

  • Can I find deals for flights from Irvine to South Carolina that include hotel bookings?

    Yes. In addition to deals on Irvine to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to South Carolina.

  • Can I find deals for business class flights from Irvine to South Carolina?

    Yes. Cheapflights offers flight deals from Irvine to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Irvine to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Irvine to South Carolina

Discover the top 7 airlines that operate flights from Irvine to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$99Average$291FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$105Average$292FlexibilityNo cancel feeOn-time65%
DeltaCheapest$141Average$481FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$249Average$493FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$256Average$296FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$291Average$494FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$318Average$517FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.