HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

Cheap flights from Irvine, CA to South Carolina

LAX — CHS
Dec 3 — Dec 101
Thu 12/3
Thu 12/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Irvine to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Irvine to South Carolina

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Popular in

November

Cheapest in

May

Average price

$653
Provider with most accurate pricing for Los Angeles-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Myrtle Beach Intl flights.
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2026
Search Deals

Cheapflights Insights

Everything you need to know about your flight from Irvine to South Carolina

What is the cheapest time of day to fly from IR9 to SC?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to South Carolina as you normally would.

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Irvine to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
324 reviews

Boarding

8.4

Overall

8.2

Entertainment

6.8

Food

6.7

Crew

8.8

Comfort

8.2

Reviews

1 / 18
10.0
Excellent

James,Oct 2026

RSW - RDU

The plane was clean and modern. The crew was excellent. The flight left early and arrived ~ 30 mintues early. As such, our bags were delayed in arriving. Food (snacks) were average.
Breeze Airways
8.2
Very good
324 reviews
Breeze Airways
8.2
Very good
324 reviews

Boarding

8.4

Overall

8.2

Entertainment

6.8

Food

6.7

Crew

8.8

Comfort

8.2

Reviews

1 / 18
10.0
Excellent

James,Oct 2026

RSW - RDU

The plane was clean and modern. The crew was excellent. The flight left early and arrived ~ 30 mintues early. As such, our bags were delayed in arriving. Food (snacks) were average.
Southwest
8.0
Very good
4,215 reviews
Breeze Airways
8.2
Very good
324 reviews

Boarding

8.4

Overall

8.2

Entertainment

6.8

Food

6.7

Crew

8.8

Comfort

8.2

Reviews

1 / 18
10.0
Excellent

James,Oct 2026

RSW - RDU

The plane was clean and modern. The crew was excellent. The flight left early and arrived ~ 30 mintues early. As such, our bags were delayed in arriving. Food (snacks) were average.
Delta
7.8
Good
8,696 reviews
Breeze Airways
8.2
Very good
324 reviews

Boarding

8.4

Overall

8.2

Entertainment

6.8

Food

6.7

Crew

8.8

Comfort

8.2

Reviews

1 / 18
10.0
Excellent

James,Oct 2026

RSW - RDU

The plane was clean and modern. The crew was excellent. The flight left early and arrived ~ 30 mintues early. As such, our bags were delayed in arriving. Food (snacks) were average.
United Airlines
7.3
Good
10,460 reviews
Breeze Airways
8.2
Very good
324 reviews

Boarding

8.4

Overall

8.2

Entertainment

6.8

Food

6.7

Crew

8.8

Comfort

8.2

Reviews

1 / 18
10.0
Excellent

James,Oct 2026

RSW - RDU

The plane was clean and modern. The crew was excellent. The flight left early and arrived ~ 30 mintues early. As such, our bags were delayed in arriving. Food (snacks) were average.
American Airlines
7.0
Good
12,229 reviews
Breeze Airways
8.2
Very good
324 reviews

Boarding

8.4

Overall

8.2

Entertainment

6.8

Food

6.7

Crew

8.8

Comfort

8.2

Reviews

1 / 18
10.0
Excellent

James,Oct 2026

RSW - RDU

The plane was clean and modern. The crew was excellent. The flight left early and arrived ~ 30 mintues early. As such, our bags were delayed in arriving. Food (snacks) were average.

Related info for your journey

  • How popular is this Irvine to South Carolina flight route?

    This flight path from Irvine to South Carolina was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Irvine to South Carolina one-way?

    To fly one-way, consider booking your trip with Breeze Airways, which is currently one of the cheapest options available, starting at $108. JetBlue flights start at $126 while deals on United Airlines start at $138 one-way.

  • What are the most popular routes from Irvine to South Carolina?

    When deciding which route to take from Irvine to South Carolina consider Los Angeles - Charlotte Douglas, Los Angeles - Charleston or Los Angeles - Greenville as they are the most popular.

  • What are the cheapest flights from Irvine to South Carolina?

    The cheapest flight price from Irvine to South Carolina is $129. On average you can expect to pay $250. The most popular route, (Los Angeles - Charlotte Douglas), can usually be booked for $240.

  • Can I find deals for flights from Irvine to South Carolina that include hotel bookings?

    Yes. In addition to deals on Irvine to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to South Carolina.

  • Can I find deals for business class flights from Irvine to South Carolina?

    Yes. Cheapflights offers flight deals from Irvine to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Irvine to South Carolina

San Francisco to John F Kennedy Intl flights
San Francisco to Newark flights
Los Angeles to Honolulu flights
San Francisco to LaGuardia flights
Long Beach to Honolulu flights
Burbank to Honolulu flights
Ontario to Honolulu flights
Los Angeles to John F Kennedy Intl flights
Los Angeles to Newark flights
Los Angeles to Dallas/Fort Worth flights
San Francisco to Ontario flights
San Francisco to Los Angeles flights
Los Angeles to Seattle flights
Los Angeles to LaGuardia flights
Los Angeles to Las Vegas flights
Ontario to Seattle flights
Los Angeles to Miami flights
Los Angeles to O'Hare Intl flights
San Francisco to Las Vegas flights
Los Angeles to San Francisco flights
Los Angeles to Hobby flights
San Francisco to Dallas/Fort Worth flights
San Francisco to Seattle flights
Ontario to San Francisco flights
San Francisco to Santa Ana flights
Los Angeles to Orlando flights
Los Angeles to George Bush Intcntl flights
Santa Ana to Las Vegas flights
San Jose to Los Angeles flights
Los Angeles to Atlanta flights
Los Angeles to Boston flights
San Francisco to O'Hare Intl flights
San Francisco to Honolulu flights
Ontario to Dallas/Fort Worth flights
Santa Ana to San Francisco flights
Los Angeles to Dulles Intl flights
Los Angeles to Sky Harbor Intl flights
San Jose to Seattle flights
Los Angeles to Denver flights
San Francisco to Boston flights
San Francisco to Sky Harbor Intl flights
Los Angeles to Fort Lauderdale flights
Los Angeles to Reagan-National flights
Los Angeles to Austin flights
Santa Ana to Dallas/Fort Worth flights
San Francisco to Miami flights
Los Angeles to Portland flights
San Francisco to Orlando flights
Los Angeles to San Jose flights

Top 6 airlines flying from Irvine to South Carolina

AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$188Average$364FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$223Average$525FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$245Average$554FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$252Average$539FlexibilityNo cancel feeOn-time69%
JetBlueCheapest$273Average$326FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$296Average$540FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.