$102+ Cheap flights from Irvine, CA to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — CHS
Oct 20 — Oct 271
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Irvine to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Irvine to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Irvine to South CarolinaExplore the most affordable flight options available from Irvine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
Explore the most affordable flight options available from Irvine to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 20, 2026.
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:50 am -
1 stop7h 20m
Sat 11/76:40 am -
1 stop7h 15m
Deal found 9/16![Southwest logo]()
$214
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:01 pm -
1 stop7h 56m
Wed 10/284:34 pm -
1 stop9h 02m
Deal found 9/16![American Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:30 pm -
1 stop6h 30m
Fri 10/308:45 pm -
1 stop7h 45m
Deal found 9/15![Southwest logo]()
$230
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:35 pm -
1 stop8h 52m
Sat 10/178:00 am -
1 stop8h 06m
Deal found 9/16![United Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:00 pm -
1 stop9h 20m
Thu 12/106:35 am -
2 stops9h 50m
Deal found 9/16![Southwest logo]()
$242
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:45 am -
2 stops9h 55m
Mon 11/28:55 pm -
1 stop7h 30m
Deal found 9/16![Southwest logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:51 pm -
Nonstop4h 47m
Sat 10/39:23 am -
Nonstop5h 43m
Deal found 9/17![Breeze Airways logo]()
$252
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:35 am -
1 stop7h 39m
Fri 11/65:05 am -
1 stop7h 30m
Deal found 9/15![American Airlines logo]()
$254
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:01 pm -
1 stop8h 04m
Sat 10/315:05 am -
1 stop9h 05m
Deal found 9/16![American Airlines logo]()
$258
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:01 pm -
1 stop7h 46m
Wed 10/285:00 am -
1 stop7h 25m
Deal found 9/16![American Airlines logo]()
$261
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:45 am -
1 stop9h 00m
Tue 11/312:47 pm -
1 stop8h 00m
Deal found 9/16![American Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:50 am -
1 stop6h 15m
Tue 11/36:45 pm -
1 stop7h 45m
Deal found 9/15![Southwest logo]()
$261
Best flights from Irvine to South CarolinaDiscover carefully curated flight deals from Irvine to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
Discover carefully curated flight deals from Irvine to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 20, 2026.
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:20 am -
1 stop9h 00m
Sat 11/146:40 am -
1 stop7h 15m
Deal found 9/17![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:50 pm -
1 stop10h 22m
Tue 10/276:05 am -
1 stop12h 00m
Deal found 9/17![Delta logo]()
$291
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:17 pm -
1 stop9h 21m
Sat 11/74:18 pm -
1 stop7h 30m
Deal found 9/18![United Airlines logo]()
$357
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop8h 10m
Wed 11/1812:25 pm -
1 stop7h 18m
Deal found 9/19![American Airlines logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:51 pm -
Nonstop4h 47m
Wed 10/219:23 am -
Nonstop5h 43m
Deal found 9/19![Breeze Airways logo]()
$448
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:40 pm -
1 stop6h 57m
Sat 10/1012:23 pm -
2 stops14h 01m
Deal found 9/19![Multiple Airlines logo]()
$461
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:50 am -
1 stop6h 35m
Sat 11/77:05 am -
1 stop6h 50m
Deal found 9/17![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:50 pm -
1 stop9h 17m
Wed 11/186:56 pm -
1 stop8h 56m
Deal found 9/15![Delta logo]()
$297
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/137:00 am -
1 stop11h 26m
Sat 2/277:25 am -
1 stop12h 20m
Deal found 9/15![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:40 am -
2 stops9h 25m
Sat 12/126:40 am -
2 stops11h 25m
Deal found 9/16![Southwest logo]()
$340
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:05 pm -
1 stop7h 53m
Sat 10/244:25 pm -
1 stop7h 52m
Deal found 9/15![United Airlines logo]()
$406
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:40 am -
2 stops8h 35m
Mon 11/166:45 pm -
1 stop7h 50m
Deal found 9/19![Southwest logo]()
$342
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:05 pm -
1 stop9h 15m
Fri 11/64:30 pm -
1 stop7h 05m
Deal found 9/14![Delta logo]()
$347
This Alaska Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:16 am -
2 stops12h 43m
Sat 10/35:20 am -
1 stop9h 49m
Deal found 9/19![Alaska Airlines logo]()
$864
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:05 am -
2 stops8h 55m
Mon 12/73:10 pm -
2 stops8h 35m
Deal found 9/16![Southwest logo]()
$350
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
1 stop5h 55m
Fri 11/137:33 pm -
1 stop8h 19m
Deal found 9/19![Delta logo]()
$365
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:37 pm -
1 stop8h 19m
Tue 11/171:55 pm -
1 stop8h 32m
Deal found 9/18![American Airlines logo]()
$489
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:40 am -
1 stop9h 55m
Mon 10/268:55 pm -
1 stop7h 35m
Deal found 9/16![Southwest logo]()
$352
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:00 pm -
1 stop11h 35m
Sat 10/172:51 pm -
1 stop8h 48m
Deal found 9/19![United Airlines logo]()
$475
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:30 am -
2 stops10h 15m
Sat 10/31:40 pm -
1 stop9h 38m
Deal found 9/17![American Airlines logo]()
$510
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:50 am -
1 stop6h 32m
Sat 10/103:38 pm -
1 stop9h 42m
Deal found 9/19![United Airlines logo]()
$478
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:50 am -
2 stops9h 25m
Fri 10/304:45 pm -
2 stops10h 25m
Deal found 9/19![Southwest logo]()
$365
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:50 pm -
1 stop8h 35m
Tue 10/137:10 pm -
1 stop8h 33m
Deal found 9/17![Delta logo]()
$418
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:25 pm -
1 stop10h 10m
Fri 10/231:20 pm -
1 stop9h 11m
Deal found 9/17![United Airlines logo]()
$479
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:45 am -
1 stop8h 40m
Tue 10/276:10 pm -
1 stop8h 05m
Deal found 9/15![Southwest logo]()
$368
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:57 am -
1 stop8h 18m
Sun 12/69:01 am -
1 stop7h 57m
Deal found 9/19![American Airlines logo]()
$539
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:10 pm -
2 stops12h 32m
Wed 11/112:18 pm -
1 stop7h 26m
Deal found 9/15![Delta logo]()
$429
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:25 pm -
1 stop10h 10m
Sat 10/242:51 pm -
1 stop10h 29m
Deal found 9/15![United Airlines logo]()
$490
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:55 am -
2 stops9h 45m
Sun 11/158:55 pm -
1 stop7h 35m
Deal found 9/18![Southwest logo]()
$372
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:06 am -
1 stop9h 06m
Sat 10/175:09 am -
1 stop9h 01m
Deal found 9/16![American Airlines logo]()
$551
Last-minute flights from Irvine to South CarolinaDiscover last-minute flight deals from Irvine to South Carolina. Data last updated September 20, 2026 and is based on user searches.
Discover last-minute flight deals from Irvine to South Carolina. Data last updated September 20, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:51 pm -
Nonstop4h 47m
Sat 10/39:23 am -
Nonstop5h 43m
Deal found 9/17![Breeze Airways logo]()
$252
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:35 pm -
1 stop8h 52m
Sat 10/178:00 am -
1 stop8h 06m
Deal found 9/16![United Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:01 pm -
1 stop7h 56m
Wed 10/284:34 pm -
1 stop9h 02m
Deal found 9/16![American Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:01 pm -
1 stop8h 04m
Sat 10/315:05 am -
1 stop9h 05m
Deal found 9/16![American Airlines logo]()
$258
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:01 pm -
1 stop7h 46m
Wed 10/285:00 am -
1 stop7h 25m
Deal found 9/16![American Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:30 pm -
1 stop6h 30m
Fri 10/308:45 pm -
1 stop7h 45m
Deal found 9/15![Southwest logo]()
$230
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:45 am -
1 stop9h 00m
Tue 11/312:47 pm -
1 stop8h 00m
Deal found 9/16![American Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:50 am -
1 stop6h 15m
Tue 11/36:45 pm -
1 stop7h 45m
Deal found 9/15![Southwest logo]()
$261
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:45 am -
2 stops9h 55m
Mon 11/28:55 pm -
1 stop7h 30m
Deal found 9/16![Southwest logo]()
$251
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:35 am -
1 stop7h 39m
Fri 11/65:05 am -
1 stop7h 30m
Deal found 9/15![American Airlines logo]()
$254
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:45 am -
2 stops9h 55m
Fri 11/64:30 pm -
1 stop9h 50m
Deal found 9/15![Southwest logo]()
$260
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:50 am -
1 stop7h 20m
Sat 11/76:40 am -
1 stop7h 15m
Deal found 9/16![Southwest logo]()
$214
One-way flights from Irvine to South CarolinaSearch for one-way flight options from Irvine to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
Search for one-way flight options from Irvine to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 20, 2026.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:15 am -
1 stop8h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$102
This JetBlue deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:35 pm -
1 stop10h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![JetBlue logo]()
$107
This JetBlue deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:30 pm -
1 stop10h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![JetBlue logo]()
$115
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:30 pm -
1 stop7h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![United Airlines logo]()
$119
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/131:05 am -
2 stops8h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$120
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:10 am -
1 stop8h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Southwest logo]()
$124
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:00 pm -
1 stop9h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:51 pm -
Nonstop4h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Breeze Airways logo]()
$129
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:38 am -
1 stop9h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![American Airlines logo]()
$130
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/276:10 am -
1 stop7h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$131
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:35 pm -
1 stop9h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$131
This Super.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:15 pm -
1 stop12h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Breeze Airways logo]()
$131
Find flight deals from Irvine to South Carolina
Keep the following information in mind while searching for Irvine to South Carolina flight deals. Data was last updated September 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $214 (Southwest) |
One-way from | $102 (American Airlines) |
Popular in | November |
Cheapest in | May |
Average price | $447 |
Cheapflights Fare Finder
Customize your flight search to find flights from Irvine to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
Use the filters below to find and compare flights from Irvine to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Los AngelesCharleston
LAX Los Angeles Los Angeles - CHS Charleston
LAXCHS
Los Angeles Los Angeles
Mon 11/9
8:30 pm-10:00 am
1 stop10h 30m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$115
Los AngelesCharleston
LAX Los Angeles Los Angeles - CHS Charleston
LAXCHS
Los Angeles Los Angeles
Sat 10/10
11:30 pm-10:02 am
1 stop7h 32m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$119
Los AngelesCharleston
LAX Los Angeles Los Angeles - CHS Charleston
LAXCHS
Los Angeles Los Angeles
Tue 12/1
10:10 am-9:40 pm
1 stop8h 30m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$124
Los AngelesCharleston
LAX Los Angeles Los Angeles - CHS Charleston
LAXCHS
Los Angeles Los Angeles
Fri 10/16
9:00 pm-9:09 am
1 stop9h 09m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$128
Los AngelesSavannah
LAX Los Angeles Los Angeles - SAV Savannah/Hilton Head
LAXSAV
Los Angeles Los Angeles
Sat 2/27
6:10 am-4:20 pm
1 stop7h 10m
Savannah/Hilton Head
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$131
Quickest round-trip
Los AngelesCharleston
LAX Los Angeles Los Angeles - CHS Charleston
LAXCHS
Los Angeles Los Angeles
Sat 9/26
12:51 pm-8:38 pm
Nonstop4h 47m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$134
Los AngelesGreenville
LAX Los Angeles Los Angeles - GSP Greenville
LAXGSP
Los Angeles Los Angeles
Tue 10/20
12:50 am-12:40 pm
2 stops8h 50m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$136
Los AngelesMyrtle Beach
LAX Los Angeles Los Angeles - MYR Myrtle Beach Intl
LAXMYR
Los Angeles Los Angeles
Wed 10/21
11:06 am-10:02 pm
1 stop7h 56m
Myrtle Beach Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$146
Los AngelesCharleston
LAX Los Angeles Los Angeles - CHS Charleston
LAXCHS
Los Angeles Los Angeles
Tue 12/1
10:45 pm-12:21 pm
1 stop10h 36m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$146
Los AngelesSavannah
LAX Los Angeles Los Angeles - SAV Savannah/Hilton Head
LAXSAV
Los Angeles Los Angeles
Tue 10/13
10:35 pm-11:00 am
1 stop9h 25m
Savannah/Hilton Head
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$146
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Irvine to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Irvine with our price prediction graph.
LAX-CHS
LAX-MYR
LAX-CLT
LAX-GSP
LAX-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Irvine to South Carolina
IR9-USSC
LAX-CHS
LAX-MYR
LAX-CLT
LAX-GSP
What is the cheapest time of day to fly from IR9 to SC?
Find hourly flight availability from Irvine to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 20, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to South Carolina as you normally would.
How much does it cost to fly round-trip from Irvine to South Carolina?
Airfare is below average for this route at the moment.
Irvine to South Carolina flights typically cost between $282 and $485 in October.The cheapest round-trip price found within the last 5 days was $214 on Southwest (Oct 31-Nov 7).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 20, 2026.
Get a feel of what it's like to fly with Breeze Airways,Southwest, andDelta from Irvine to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.8
Food
6.8
Boarding
8.4
Comfort
8.2
Overall
8.2
Entertainment
6.8
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Food
6.8
Boarding
8.4
Comfort
8.2
Overall
8.2
Entertainment
6.8
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Food
6.8
Boarding
8.4
Comfort
8.2
Overall
8.2
Entertainment
6.8
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Food
6.8
Boarding
8.4
Comfort
8.2
Overall
8.2
Entertainment
6.8
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Food
6.8
Boarding
8.4
Comfort
8.2
Overall
8.2
Entertainment
6.8
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Food
6.8
Boarding
8.4
Comfort
8.2
Overall
8.2
Entertainment
6.8
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Irvine to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Alternative routes for Irvine to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Irvine to South Carolina by cabin class
Find flights from Irvine to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Irvine and South Carolina flights
Browse other Irvine and South Carolina flight options. Last updated on September 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Irvine after your stay in South Carolina
Top 6 airlines flying from Irvine to South Carolina
Discover the top 6 airlines that operate flights from Irvine to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$188 | Average$362 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$228 | Average$520 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$252 | Average$533 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$274 | Average$326 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$296 | Average$540 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$318 | Average$557 | FlexibilityNo cancel fee | On-time63% |