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South Carolina

$49+ Cheap flights from Durham, NC to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — CHS
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Durham to South Carolina

Cheapest flights from Durham to South Carolina
Explore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/249:25 pm
RDU
-
CLT
1 stop16h 26m
Multiple Airlines
Tue 3/35:54 pm
CLT
-
RDU
1 stop23h 17m
Multiple Airlines
Deal found 1/27$128
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:08 pm
RDU
-
MYR
1 stop14h 50m
Spirit Airlines
Wed 3/410:09 am
MYR
-
RDU
1 stop7h 02m
Spirit Airlines
Deal found 1/28$134
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1510:47 am
RDU
-
CHS
1 stop3h 49m
Multiple Airlines
Thu 2/195:00 pm
CHS
-
RDU
1 stop24h 11m
Multiple Airlines
Deal found 1/27$144
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/233:08 pm
RDU
-
MYR
1 stop17h 05m
Spirit Airlines
Wed 2/2510:09 am
MYR
-
RDU
1 stop7h 02m
Spirit Airlines
Deal found 1/26$150
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/99:56 pm
RDU
-
CHS
1 stop10h 42m
Multiple Airlines
Thu 2/126:15 am
CHS
-
RDU
1 stop3h 52m
Multiple Airlines
Deal found 1/28$153
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:25 pm
RDU
-
CHS
1 stop21h 35m
Multiple Airlines
Thu 3/263:11 pm
CHS
-
RDU
1 stop22h 43m
Multiple Airlines
Deal found 1/28$165
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/119:25 pm
RDU
-
CHS
1 stop11h 13m
Multiple Airlines
Thu 2/195:00 pm
CHS
-
RDU
1 stop24h 11m
Multiple Airlines
Deal found 1/27$166
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:08 pm
RDU
-
CLT
3 stops29h 48m
Spirit Airlines
Tue 3/39:21 am
CLT
-
RDU
1 stop7h 50m
Spirit Airlines
Deal found 1/27$170
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/1510:47 am
RDU
-
CHS
1 stop3h 49m
Multiple Airlines
Tue 2/175:00 pm
CHS
-
RDU
1 stop24h 11m
Multiple Airlines
Deal found 1/28$171
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/136:54 pm
RDU
-
CHS
2 stops22h 46m
Multiple Airlines
Sun 2/156:15 am
CHS
-
RDU
1 stop3h 52m
Multiple Airlines
Deal found 1/27$176
This Priceline deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:30 am
RDU
-
SAV
1 stop5h 52m
JetBlue
Fri 3/65:20 pm
SAV
-
RDU
1 stop6h 32m
JetBlue
Deal found 1/28$183
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:08 pm
RDU
-
CHS
1 stop21h 57m
Multiple Airlines
Sun 3/16:15 am
CHS
-
RDU
1 stop3h 52m
Multiple Airlines
Deal found 1/27$183

Find flight deals from Durham to South Carolina

Keep the following information in mind while searching for Durham to South Carolina flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$128
(Kiwi.com)

One-way from

$49
(Breeze Airways)
Provider with most accurate pricing for Raleigh-Durham-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Myrtle Beach Intl flights.
Search Deals
From Durham to South Carolina
Search Deals
One-way flight from Durham to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Durham to South Carolina that are best for you.

Fly from

Durham

Fly to

South Carolina

Route

Depart

Return

Price

RaleighMyrtle Beach

RDU - MYR

RDUMYR

Raleigh-Durham

Mon 2/23

3:08 pm-8:13 am

1 stop17h 05m

Myrtle Beach Intl

Wed 2/25

10:09 am-5:11 pm

1 stop7h 02m

$150

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Mon 2/9

9:56 pm-8:38 am

1 stop10h 42m

Charleston

Thu 2/12

6:15 am-10:07 am

1 stop3h 52m

$153

RaleighMyrtle Beach

RDU - MYR

RDUMYR

Raleigh-Durham

Wed 2/25

6:08 pm-8:58 am

1 stop14h 50m

Myrtle Beach Intl

Wed 3/4

9:54 pm-2:13 pm

2 stops16h 19m

$161

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Fri 2/13

6:54 pm-5:40 pm

2 stops22h 46m

Charleston

Sun 2/15

6:15 am-10:07 am

1 stop3h 52m

$176

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Fri 2/27

6:08 pm-4:05 pm

1 stop21h 57m

Charleston

Sun 3/1

6:15 am-10:07 am

1 stop3h 52m

$183

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Tue 4/28

5:52 pm-8:40 am

1 stop14h 48m

Charleston

Thu 4/30

9:35 am-6:38 pm

1 stop9h 03m

$192

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Fri 2/27

2:34 pm-9:53 pm

1 stop7h 19m

Charleston

Mon 3/2

1:19 pm-5:50 pm

1 stop4h 31m

$195

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Sat 3/7

6:08 pm-3:05 pm

1 stop20h 57m

Charleston

Sat 3/14

12:15 pm-8:29 am

1 stop20h 14m

$196

RaleighSavannah

RDU - SAV

RDUSAV

Raleigh-Durham

Wed 3/11

6:08 pm-11:21 am

1 stop17h 13m

Savannah/Hilton Head

Sat 3/14

12:22 pm-5:29 pm

1 stop5h 07m

$199

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Sat 3/21

5:45 am-10:33 pm

2 stops16h 48m

Charleston

Thu 3/26

3:11 pm-1:54 pm

1 stop22h 43m

$199

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 60 results
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Best time to book a flight from Durham to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to South Carolina

What is the cheapest month to book a flight from Durham to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Durham to South Carolina (average of $54). Flying from Durham to South Carolina in December is currently the most expensive (average of $363). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SC?

Find hourly flight availability from Durham to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

One of the essential ways to save on airfare from Durham to South Carolina is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 86% on airfare.

What is the cheapest day to fly from Durham to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Durham to South Carolina. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their Durham to South Carolina flight should consider departing on Monday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with Breeze Airways, Delta, and American Airlines from Durham to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
263 reviews

Boarding

8.3

Food

6.7

Overall

8.2

Crew

8.7

Entertainment

6.6

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Breeze Airways
8.2
Very good
263 reviews
Breeze Airways
8.2
Very good
263 reviews

Boarding

8.3

Food

6.7

Overall

8.2

Crew

8.7

Entertainment

6.6

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Delta
7.9
Good
8,127 reviews
Breeze Airways
8.2
Very good
263 reviews

Boarding

8.3

Food

6.7

Overall

8.2

Crew

8.7

Entertainment

6.6

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
American Airlines
7.2
Good
11,206 reviews
Breeze Airways
8.2
Very good
263 reviews

Boarding

8.3

Food

6.7

Overall

8.2

Crew

8.7

Entertainment

6.6

Comfort

8.2

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.

Related info for your journey

Find useful and relevant information for your journey from Durham to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Durham to South Carolina?

    Departing from Durham to South Carolina will take you 3h 22m. Durham and South Carolina are separated by a distance of 188 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Durham to South Carolina one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $125. Users have also found prices from $140 and $146 on JetBlue and Southwest, respectively.

  • What are the most popular routes from Durham to South Carolina?

    When deciding which route to take from Durham to South Carolina consider Raleigh-Durham - Charlotte Douglas, Raleigh-Durham - Myrtle Beach Intl or Raleigh-Durham - Savannah/Hilton Head as they are the most popular.

  • Can I find deals for flights from Durham to South Carolina that include hotel bookings?

    Yes. In addition to deals on Durham to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South Carolina.

  • Can I find deals for business class flights from Durham to South Carolina?

    Yes. Cheapflights offers flight deals from Durham to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Durham to South Carolina (average of $54). Flying from Durham to South Carolina in December is currently the most expensive (average of $363). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Durham to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Durham to South Carolina

Discover the top 3 airlines that operate flights from Durham to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$68Average$187FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$447FlexibilityNo cancel feeOn-time71%
DeltaCheapest$275Average$457FlexibilityNo cancel feeOn-timeN/A

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