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South Carolina

$67+ Cheap flights from Durham, NC to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — CHS
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Durham to South Carolina

Cheapest flights from Durham to South Carolina
Explore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/158:14 pmRDU - CHS
1 stop12h 23mMultiple Airlines
Sun 12/2110:18 pmCHS - RDU
1 stop18h 37mMultiple Airlines
Deal found 12/14$258
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:14 pmRDU - GSP
1 stop14h 39mMultiple Airlines
Mon 1/53:34 pmGSP - RDU
2 stops32h 38mMultiple Airlines
Deal found 12/13$263
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:07 pmRDU - GSP
1 stop19h 46mBreeze Airways
Mon 1/59:46 pmGSP - RDU
1 stop13h 20mBreeze Airways
Deal found 12/13$286
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:42 amRDU - CLT
2 stops29h 30mMultiple Airlines
Sun 12/219:34 pmCLT - RDU
1 stop10h 39mMultiple Airlines
Deal found 12/13$293
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:00 amRDU - CLT
2 stops26h 00mMultiple Airlines
Mon 12/299:43 pmCLT - RDU
1 stop10h 31mMultiple Airlines
Deal found 12/13$295
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amRDU - CLT
2 stops14h 09mMultiple Airlines
Sat 1/310:38 pmCLT - RDU
1 stop22h 57mMultiple Airlines
Deal found 12/14$296
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/147:52 pmRDU - MYR
1 stop22h 19mMultiple Airlines
Sun 12/217:32 pmMYR - RDU
1 stop12h 41mMultiple Airlines
Deal found 12/13$299
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:50 pmRDU - CHS
1 stop27h 33mMultiple Airlines
Thu 1/17:00 amCHS - RDU
1 stop24h 21mMultiple Airlines
Deal found 12/13$309
This Kiwi.com deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:42 amRDU - SAV
2 stops38h 32mMultiple Airlines
Sun 1/41:23 pmSAV - RDU
1 stop29h 00mMultiple Airlines
Deal found 12/12$311
This eDestinos deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/141:39 pmRDU - CLT
1 stop18h 20mFrontier
Sun 12/219:33 pmCLT - RDU
1 stop10h 40mFrontier
Deal found 12/13$343
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:54 pmRDU - SAV
1 stop18h 34mMultiple Airlines
Mon 12/227:30 amSAV - RDU
1 stop9h 25mMultiple Airlines
Deal found 12/13$344
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/158:14 pmRDU - CLT
1 stop13h 36mMultiple Airlines
Mon 12/229:34 pmCLT - RDU
1 stop10h 40mMultiple Airlines
Deal found 12/14$346

Find flight deals from Durham to South Carolina

Keep the following information in mind while searching for Durham to South Carolina flight deals. Data was last updated December 15, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$91
(Super.com)

One-way from

$67
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$486
Provider with most accurate pricing for Raleigh-Durham-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Myrtle Beach Intl flights.
Search Deals
From Durham to South Carolina
Search Deals
One-way flight from Durham to South Carolina
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Durham to South Carolina that are best for you.

Fly from

Durham

Fly to

South Carolina

Route

Depart

Return

Price

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Thu 1/8

10:47 am-2:36 pm

1 stop3h 49m

Charleston

Sun 1/11

6:15 am-10:07 am

1 stop3h 52m

$92

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Thu 2/5

10:47 am-2:36 pm

1 stop3h 49m

Charleston

Sun 2/8

6:15 am-10:07 am

1 stop3h 52m

$103

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Tue 1/6

6:00 am-11:28 am

1 stop5h 28m

Charleston

Thu 1/8

6:15 am-10:07 am

1 stop3h 52m

$127

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Sun 1/11

3:08 pm-5:36 pm

1 stop26h 28m

Charleston

Sun 1/18

6:15 am-10:07 am

1 stop3h 52m

$131

RaleighCharlotte

RDU - CLT

RDUCLT

Raleigh-Durham

Tue 2/24

9:25 pm-1:51 pm

1 stop16h 26m

Charlotte Douglas

Tue 3/3

5:54 pm-7:21 pm

1 stop25h 27m

$133

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Mon 2/2

9:56 pm-8:38 am

1 stop10h 42m

Charleston

Thu 2/5

6:15 am-10:07 am

1 stop3h 52m

$134

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Sun 2/8

10:47 am-2:36 pm

1 stop3h 49m

Charleston

Tue 2/10

3:01 pm-8:30 pm

1 stop5h 29m

$139

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Thu 1/8

6:10 am-5:36 pm

2 stops11h 26m

Charleston

Sun 1/11

6:15 am-10:07 am

1 stop3h 52m

$140

RaleighCharlotte

RDU - CLT

RDUCLT

Raleigh-Durham

Sun 1/11

10:11 pm-9:02 am

1 stop10h 51m

Charlotte Douglas

Mon 1/12

10:39 pm-1:58 pm

1 stop15h 19m

$142

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Fri 2/6

2:34 pm-9:53 pm

1 stop7h 19m

Charleston

Sun 2/8

6:15 am-10:07 am

1 stop3h 52m

$146

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/12

Showing 1-10 of 60 results
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Best time to book a flight from Durham to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to South Carolina

What is the cheapest month to book a flight from Durham to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Durham to South Carolina (average of $54). Flying from Durham to South Carolina in December is currently the most expensive (average of $363). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SC?

Find hourly flight availability from Durham to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

One of the essential ways to save on airfare from Durham to South Carolina is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 19% on airfare.

What is the cheapest day to fly from Durham to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Durham to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Durham to South Carolina flight should consider departing on Monday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 15, 2025.
Get a feel of what it's like to fly with Breeze Airways, Delta, and American Airlines from Durham to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.2
Very good
248 reviews

Entertainment

6.7

Crew

8.8

Food

6.7

Overall

8.2

Boarding

8.4

Comfort

8.2

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Breeze Airways
8.2
Very good
248 reviews
Breeze Airways
8.2
Very good
248 reviews

Entertainment

6.7

Crew

8.8

Food

6.7

Overall

8.2

Boarding

8.4

Comfort

8.2

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
Delta
7.9
Good
8,008 reviews
Breeze Airways
8.2
Very good
248 reviews

Entertainment

6.7

Crew

8.8

Food

6.7

Overall

8.2

Boarding

8.4

Comfort

8.2

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.
American Airlines
7.2
Good
11,048 reviews
Breeze Airways
8.2
Very good
248 reviews

Entertainment

6.7

Crew

8.8

Food

6.7

Overall

8.2

Boarding

8.4

Comfort

8.2

Reviews

1 / 16
10.0
Excellent

Anonymous,Dec 2025

RSW - ISP

There was no food offered so I had to just put okay. Other than that all was great.

Related info for your journey

Find useful and relevant information for your journey from Durham to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Durham to South Carolina?

    Departing from Durham to South Carolina will take you 3h 03m. Durham and South Carolina are separated by a distance of 152 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Durham to South Carolina one-way?

    For one-way options, check prices for Breeze Airways. According to our data, you can fly for as low as $33. Users have also found prices from $79 and $98 on Delta and American Airlines, respectively.

  • What are the most popular routes from Durham to South Carolina?

    When deciding which route to take from Durham to South Carolina consider Raleigh-Durham - Savannah/Hilton Head, Raleigh-Durham - Charlotte Douglas or Raleigh-Durham - Myrtle Beach Intl as they are the most popular.

  • Can I find deals for flights from Durham to South Carolina that include hotel bookings?

    Yes. In addition to deals on Durham to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South Carolina.

  • Can I find deals for business class flights from Durham to South Carolina?

    Yes. Cheapflights offers flight deals from Durham to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Durham to South Carolina (average of $54). Flying from Durham to South Carolina in December is currently the most expensive (average of $363). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Durham to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Durham to South Carolina

Discover the top 3 airlines that operate flights from Durham to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$71Average$187FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$446FlexibilityNo cancel feeOn-time71%
DeltaCheapest$283Average$457FlexibilityNo cancel feeOn-timeN/A

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