South Carolina

$88+ Cheap flights from Durham, NC to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — CHS
ago. 5 — ago. 121
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Cheap flight deals from Durham to South Carolina

Keep the following information in mind while searching for Durham to South Carolina flight deals. Data was last updated julio 31, 2025.

Round-trip from

$100
(Priceline)

One-way from

$88
(Mytrip)

Popular in

March

Cheapest in

May

Average price

$367
From Durham to South Carolina
One-way flight from Durham to South Carolina
Highest demand for flights based on searches. 17% potential increase in price ($75 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Average for round-trip flights in July 2025

Find flight deals from Durham to South Carolina

Cheapest flights from Durham to South Carolina
Explore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 31, 2025.

This Priceline deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/2411:21 amRDU - CHS
1 stop3h 42mBreeze Airways
jue. 8/287:00 amCHS - RDU
1 stop3h 41mBreeze Airways
Deal found 7/30$100
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/309:49 pmRDU - CHS
1 stop19h 18mSpirit Airlines
dom. 11/26:08 pmCHS - RDU
1 stop14h 20mSpirit Airlines
Deal found 7/29$181
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/227:56 pmRDU - CLT
1 stop14h 29mSpirit Airlines
lun. 8/257:00 amCLT - RDU
1 stop11h 51mSpirit Airlines
Deal found 7/29$195
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/203:08 pmRDU - SAV
1 stop6h 17mDelta
jue. 9/255:20 amSAV - RDU
1 stop3h 31mDelta
Deal found 7/31$197
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/2812:49 pmRDU - CHS
1 stop4h 27mAmerican Airlines
mar. 9/27:38 pmCHS - RDU
1 stop3h 30mAmerican Airlines
Deal found 7/31$197
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/265:49 amRDU - CLT
1 stop7h 46mAmerican Airlines
vie. 9/265:25 pmCLT - RDU
Nonstop1h 01mAmerican Airlines
Deal found 7/30$211
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/265:19 pmRDU - MYR
1 stop5h 52mAmerican Airlines
mar. 9/27:24 pmMYR - RDU
1 stop3h 44mAmerican Airlines
Deal found 7/29$212
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/146:00 amRDU - SAV
1 stop4h 07mAmerican Airlines
dom. 9/215:24 amSAV - RDU
1 stop2h 42mAmerican Airlines
Deal found 7/31$218
This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/49:49 pmRDU - MYR
1 stop9h 11mSpirit Airlines
dom. 9/77:36 pmMYR - RDU
1 stop18h 59mSpirit Airlines
Deal found 7/30$223
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/125:16 pmRDU - GSP
1 stop5h 42mAmerican Airlines
vie. 9/197:38 pmGSP - RDU
1 stop3h 33mAmerican Airlines
Deal found 7/31$227
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/45:15 pmRDU - CHS
1 stop6h 33mDelta
lun. 10/207:59 pmCHS - RDU
1 stop4h 03mDelta
Deal found 7/29$232
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/172:25 pmRDU - SAV
1 stop6h 00mSouthwest
vie. 9/195:45 amSAV - RDU
2 stops8h 40mSouthwest
Deal found 7/30$235

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 31, 2025.
Use the filters below to find and compare flights from Durham to South Carolina that are best for you.

Fly from

Durham

Fly to

South Carolina

Route

Depart

Return

Price

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

dom. 8/24

11:21 am-3:03 pm

1 stop3h 42m

Charleston

jue. 8/28

7:00 am-10:41 am

1 stop3h 41m

$100

RaleighCharlotte

RDU - CLT

RDUCLT

Raleigh-Durham

vie. 8/22

7:56 pm-10:25 am

1 stop14h 29m

Charlotte Douglas

lun. 8/25

7:00 am-6:51 pm

1 stop11h 51m

$195

RaleighSavannah

RDU - SAV

RDUSAV

Raleigh-Durham

sáb. 9/20

3:08 pm-9:25 pm

1 stop6h 17m

Savannah/Hilton Head

jue. 9/25

5:20 am-8:51 am

1 stop3h 31m

$197

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

jue. 8/28

12:49 pm-5:16 pm

1 stop4h 27m

Charleston

mar. 9/2

7:38 pm-11:08 pm

1 stop3h 30m

$197

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

vie. 8/22

2:55 pm-8:35 pm

1 stop5h 40m

Charleston

dom. 8/24

8:17 pm-6:51 pm

1 stop22h 34m

$210

RaleighCharlotte

RDU - CLT

RDUCLT

Raleigh-Durham

vie. 9/26

5:49 am-1:35 pm

1 stop7h 46m

Charlotte Douglas

vie. 9/26

5:25 pm-6:26 pm

Nonstop1h 01m

$211

RaleighMyrtle Beach

RDU - MYR

RDUMYR

Raleigh-Durham

mar. 8/26

5:19 pm-11:11 pm

1 stop5h 52m

Myrtle Beach Intl

mar. 9/2

7:24 pm-11:08 pm

1 stop3h 44m

$212

RaleighSavannah

RDU - SAV

RDUSAV

Raleigh-Durham

dom. 9/14

6:00 am-10:07 am

1 stop4h 07m

Savannah/Hilton Head

dom. 9/21

5:24 am-8:06 am

1 stop2h 42m

$218

RaleighMyrtle Beach

RDU - MYR

RDUMYR

Raleigh-Durham

jue. 9/4

9:49 pm-7:00 am

1 stop9h 11m

Myrtle Beach Intl

dom. 9/7

7:36 pm-2:35 pm

1 stop18h 59m

$223

RaleighGreenville

RDU - GSP

RDUGSP

Raleigh-Durham

vie. 9/12

5:16 pm-10:58 pm

1 stop5h 42m

Greenville

vie. 9/19

7:38 pm-11:11 pm

1 stop3h 33m

$227

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 60 results
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Best time to book a flight from Durham to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to South Carolina

What is the cheapest month to book a flight from Durham to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Durham to South Carolina (average of $217). Flying from Durham to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SC?

Find hourly flight availability from Durham to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 31, 2025.

When flying from Durham to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated julio 31, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and Breeze Airways from Durham to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
8.0
Very good

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Comfort

8.0

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Durham to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines to fly from Durham to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $88. Users have also found prices from $89 and $99 on Frontier and Delta, respectively.

  • What are the most popular routes from Durham to South Carolina?

  • Can I find deals for flights from Durham to South Carolina that include hotel bookings?

    Yes. In addition to deals on Durham to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South Carolina.

  • Can I find deals for business class flights from Durham to South Carolina?

    Yes. Cheapflights offers flight deals from Durham to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Durham to South Carolina (average of $217). Flying from Durham to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Durham to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Durham to South Carolina

Discover the top 3 airlines that operate flights from Durham to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$71Average$187FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$158Average$473FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$433FlexibilityNo cancel feeOn-time71%

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