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South Carolina

$71+ Cheap flights from Durham, NC to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — CHS
Apr 14 — Apr 211
Tue 4/14
Tue 4/21
1 adult, Economy
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Cheap flight deals from Durham to South Carolina

Cheapest flights from Durham to South Carolina
Explore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:38 pm
RDU
-
CHS
1 stop10h 00m
Multiple Airlines
Thu 4/26:15 am
CHS
-
RDU
1 stop3h 52m
Multiple Airlines
Deal found 3/14$171
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:46 pm
RDU
-
CLT
1 stop16h 32m
Multiple Airlines
Fri 4/179:32 pm
CLT
-
RDU
1 stop13h 26m
Multiple Airlines
Deal found 3/10$173
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/68:45 pm
RDU
-
CLT
1 stop14h 12m
Multiple Airlines
Wed 4/89:18 am
CLT
-
RDU
1 stop8h 11m
Multiple Airlines
Deal found 3/10$174
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:46 pm
RDU
-
CLT
1 stop16h 32m
Multiple Airlines
Thu 4/169:32 pm
CLT
-
RDU
1 stop12h 37m
Multiple Airlines
Deal found 3/11$175
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:25 pm
RDU
-
CLT
1 stop5h 28m
Multiple Airlines
Wed 4/159:32 pm
CLT
-
RDU
1 stop12h 27m
Multiple Airlines
Deal found 3/11$176
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:03 pm
RDU
-
CLT
1 stop19h 51m
Multiple Airlines
Sun 5/106:28 am
CLT
-
RDU
1 stop7h 44m
Multiple Airlines
Deal found 3/14$185
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:25 pm
RDU
-
CLT
1 stop5h 28m
Multiple Airlines
Thu 4/169:31 am
CLT
-
RDU
1 stop6h 55m
Multiple Airlines
Deal found 3/12$191
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:32 pm
RDU
-
CHS
1 stop12h 03m
Multiple Airlines
Thu 5/76:00 am
CHS
-
RDU
1 stop12h 37m
Multiple Airlines
Deal found 3/13$192
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/199:37 pm
RDU
-
MYR
1 stop16h 36m
Multiple Airlines
Tue 4/2110:20 am
MYR
-
RDU
1 stop8h 22m
Multiple Airlines
Deal found 3/13$193
This Mytrip deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:25 pm
RDU
-
CLT
1 stop5h 28m
Spirit Airlines
Wed 4/1510:16 am
CLT
-
RDU
1 stop4h 32m
Spirit Airlines
Deal found 3/11$193
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/310:39 pm
RDU
-
CHS
1 stop23h 14m
Multiple Airlines
Thu 5/76:00 am
CHS
-
RDU
1 stop12h 37m
Multiple Airlines
Deal found 3/13$197
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2610:38 pm
RDU
-
CLT
1 stop10h 49m
Multiple Airlines
Sun 5/38:50 am
CLT
-
RDU
1 stop11h 42m
Multiple Airlines
Deal found 3/12$198

Find flight deals from Durham to South Carolina

Keep the following information in mind while searching for Durham to South Carolina flight deals. Data was last updated March 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$171
(Kiwi.com)

One-way from

$71
(Kiwi.com)
Provider with most accurate pricing for Raleigh-Durham-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Myrtle Beach Intl flights.
Search Deals
From Durham to South Carolina
Search Deals
One-way flight from Durham to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Durham to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RaleighSavannah

RDU - SAV

RDUSAV

Raleigh-Durham

Fri 4/10

8:51 am-3:55 pm

2 stops31h 04m

Savannah/Hilton Head

Fri 4/17

1:45 pm-8:32 pm

1 stop6h 47m

$217

RaleighCharleston

RDU - CHS

RDUCHS

Raleigh-Durham

Tue 4/7

2:00 pm-9:25 pm

1 stop7h 25m

Charleston

Tue 4/14

6:00 am-2:13 pm

1 stop8h 13m

$221

RaleighMyrtle Beach

RDU - MYR

RDUMYR

Raleigh-Durham

Sat 5/9

10:03 pm-9:50 am

1 stop11h 47m

Myrtle Beach Intl

Sat 5/16

3:17 pm-5:08 pm

1 stop25h 51m

$238

RaleighMyrtle Beach

RDU - MYR

RDUMYR

Raleigh-Durham

Sun 4/5

6:00 am-11:05 am

1 stop5h 05m

Myrtle Beach Intl

Wed 4/8

11:28 am-8:46 am

2 stops21h 18m

$259

RaleighMyrtle Beach

RDU - MYR

RDUMYR

Raleigh-Durham

Fri 3/27

9:37 am-8:48 pm

1 stop11h 11m

Myrtle Beach Intl

Mon 3/30

3:20 pm-9:53 pm

1 stop6h 33m

$268

RaleighGreenville

RDU - GSP

RDUGSP

Raleigh-Durham

Tue 4/7

1:25 pm-8:00 pm

1 stop6h 35m

Greenville

Tue 4/14

8:20 am-12:50 pm

1 stop4h 30m

$271

RaleighSavannah

RDU - SAV

RDUSAV

Raleigh-Durham

Wed 4/8

1:25 pm-8:25 pm

1 stop7h 00m

Savannah/Hilton Head

Wed 4/15

6:40 am-4:30 pm

2 stops9h 50m

$276

RaleighGreenville

RDU - GSP

RDUGSP

Raleigh-Durham

Wed 4/15

3:50 pm-8:00 pm

1 stop4h 10m

Greenville

Wed 4/22

6:45 am-4:30 pm

2 stops9h 45m

$276

RaleighMyrtle Beach

RDU - MYR

RDUMYR

Raleigh-Durham

Thu 3/26

3:50 pm-10:00 am

1 stop18h 10m

Myrtle Beach Intl

Mon 3/30

3:20 pm-8:37 am

1 stop17h 17m

$285

RaleighCharlotte

RDU - CLT

RDUCLT

Raleigh-Durham

Thu 4/16

3:46 pm-8:09 am

2 stops16h 23m

Charlotte Douglas

Sun 4/19

9:54 pm-2:48 pm

2 stops16h 54m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/10

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Durham to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to South Carolina

What is the cheapest month to book a flight from Durham to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Durham to South Carolina (average of $54). Flying from Durham to South Carolina in January is currently the most expensive (average of $467). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SC?

Find hourly flight availability from Durham to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 15, 2026.

One of the essential ways to save on airfare from Durham to South Carolina is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 86% on airfare.

What is the cheapest day to fly from Durham to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Durham to South Carolina. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their Durham to South Carolina flight should consider departing on Monday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 15, 2026.
Get a feel of what it's like to fly with Breeze Airways,Delta, andAmerican Airlines from Durham to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Boarding

8.3

Overall

8.1

Crew

8.7

Comfort

8.2

Food

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Breeze Airways
8.1
Very good
271 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Boarding

8.3

Overall

8.1

Crew

8.7

Comfort

8.2

Food

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Delta
7.9
Good
8,292 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Boarding

8.3

Overall

8.1

Crew

8.7

Comfort

8.2

Food

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
American Airlines
7.1
Good
11,472 reviews
Breeze Airways
8.1
Very good
271 reviews

Entertainment

6.6

Boarding

8.3

Overall

8.1

Crew

8.7

Comfort

8.2

Food

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.

Related info for your journey

Find useful and relevant information for your journey from Durham to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Durham to South Carolina?

    Departing from Durham to South Carolina will take you 6h 35m. Durham and South Carolina are separated by a distance of 205 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Durham to South Carolina one-way?

    For one-way options, check prices for Breeze Airways. According to our data, you can fly for as low as $56. Users have also found prices from $79 and $98 on Delta and American Airlines, respectively.

  • What are the most popular routes from Durham to South Carolina?

    When deciding which route to take from Durham to South Carolina consider Raleigh-Durham - Charlotte Douglas, Raleigh-Durham - Savannah/Hilton Head or Raleigh-Durham - Charleston as they are the most popular.

  • Can I find deals for flights from Durham to South Carolina that include hotel bookings?

    Yes. In addition to deals on Durham to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South Carolina.

  • Can I find deals for business class flights from Durham to South Carolina?

    Yes. Cheapflights offers flight deals from Durham to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Durham to South Carolina (average of $54). Flying from Durham to South Carolina in January is currently the most expensive (average of $467). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Durham to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Durham to South Carolina

Discover the top 3 airlines that operate flights from Durham to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$54Average$190FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$435FlexibilityNo cancel feeOn-time71%
DeltaCheapest$283Average$458FlexibilityNo cancel feeOn-timeN/A

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