$88+ Cheap flights from Detroit (DTT) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — CHS
Oct 21 — Oct 281
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Detroit to South CarolinaExplore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:59 pm -
1 stop17h 39m
Tue 10/273:00 pm -
1 stop20h 40m
Deal found 9/17![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:50 pm -
1 stop14h 48m
Tue 10/273:00 pm -
1 stop20h 40m
Deal found 9/17![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:59 pm -
1 stop17h 39m
Thu 10/296:45 am -
2 stops29h 22m
Deal found 9/17![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:50 pm -
1 stop14h 48m
Thu 10/296:45 am -
2 stops29h 22m
Deal found 9/17![Multiple Airlines logo]()
$227
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:30 am -
1 stop4h 35m
Tue 11/103:25 pm -
1 stop6h 45m
Deal found 9/17![Southwest logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:50 pm -
1 stop14h 48m
Fri 10/238:58 pm -
1 stop13h 54m
Deal found 9/16![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:03 pm -
2 stops17h 35m
Tue 10/273:00 pm -
1 stop20h 40m
Deal found 9/16![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:33 pm -
1 stop11h 55m
Tue 12/84:03 pm -
1 stop19h 10m
Deal found 9/17![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:02 pm -
1 stop14h 36m
Sat 10/313:42 pm -
1 stop18h 10m
Deal found 9/19![Multiple Airlines logo]()
$252
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
2 stops12h 25m
Sat 12/55:55 pm -
1 stop4h 05m
Deal found 9/17![Southwest logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:59 pm -
1 stop17h 39m
Wed 10/286:00 am -
2 stops18h 44m
Deal found 9/17![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:33 pm -
1 stop10h 30m
Wed 12/92:57 pm -
1 stop20h 16m
Deal found 9/18![Multiple Airlines logo]()
$255
Best flights from Detroit to South CarolinaDiscover carefully curated flight deals from Detroit to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Detroit to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:35 am -
1 stop4h 53m
Tue 11/101:06 pm -
Nonstop2h 14m
Deal found 9/19![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:02 am -
1 stop5h 08m
Sat 10/242:51 pm -
1 stop5h 58m
Deal found 9/17![United Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:20 am -
1 stop9h 40m
Mon 10/198:10 am -
1 stop6h 00m
Deal found 9/17![Southwest logo]()
$343
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/146:00 am -
1 stop6h 02m
Mon 1/1812:37 pm -
1 stop6h 47m
Deal found 9/18![American Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:07 pm -
1 stop11h 31m
Sun 11/12:13 pm -
1 stop18h 39m
Deal found 9/20![Multiple Airlines logo]()
$390
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:30 am -
2 stops6h 56m
Sat 10/2410:29 am -
1 stop7h 51m
Deal found 9/17![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:45 am -
Nonstop1h 57m
Tue 11/1011:30 am -
Nonstop2h 00m
Deal found 9/17![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:25 pm -
1 stop5h 45m
Sun 11/227:25 am -
2 stops9h 50m
Deal found 9/20![Southwest logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:00 am -
1 stop3h 47m
Tue 10/2010:23 am -
2 stops10h 17m
Deal found 9/16![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:40 am -
Nonstop2h 01m
Tue 12/86:59 pm -
1 stop5h 57m
Deal found 9/20![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:20 am -
1 stop6h 10m
Wed 10/216:40 pm -
1 stop3h 55m
Deal found 9/20![Southwest logo]()
$363
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
1 stop4h 34m
Sun 11/155:54 pm -
1 stop6h 43m
Deal found 9/19![American Airlines logo]()
$400
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:00 am -
1 stop3h 47m
Sat 10/103:03 pm -
2 stops7h 12m
Deal found 9/17![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/72:30 pm -
1 stop4h 31m
Sun 11/86:00 am -
Nonstop1h 49m
Deal found 9/20![Delta logo]()
$366
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop4h 37m
Tue 10/65:11 pm -
1 stop4h 56m
Deal found 9/17![American Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:10 am -
2 stops10h 30m
Mon 10/198:55 pm -
2 stops13h 10m
Deal found 9/17![Southwest logo]()
$371
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:10 am -
2 stops10h 05m
Mon 11/210:45 am -
2 stops10h 15m
Deal found 9/18![Southwest logo]()
$373
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:45 am -
Nonstop1h 57m
Wed 10/2811:27 am -
Nonstop1h 55m
Deal found 9/16![Delta logo]()
$384
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:49 pm -
1 stop3h 49m
Sat 10/3111:36 am -
2 stops9h 58m
Deal found 9/20![American Airlines logo]()
$434
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:15 am -
2 stops8h 02m
Sun 11/299:37 pm -
1 stop4h 52m
Deal found 9/17![United Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:05 am -
1 stop9h 30m
Sun 11/87:45 am -
2 stops9h 30m
Deal found 9/20![Southwest logo]()
$373
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:40 pm -
Nonstop2h 11m
Tue 10/276:35 pm -
Nonstop2h 15m
Deal found 9/19![Delta logo]()
$389
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:10 am -
1 stop4h 55m
Tue 10/272:13 pm -
2 stops7h 33m
Deal found 9/19![American Airlines logo]()
$434
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:55 pm -
1 stop5h 55m
Thu 10/152:10 pm -
1 stop9h 45m
Deal found 9/17![Southwest logo]()
$378
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:19 am -
1 stop4h 07m
Mon 10/55:38 pm -
1 stop6h 21m
Deal found 9/20![United Airlines logo]()
$421
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:49 pm -
Nonstop2h 16m
Fri 10/236:50 pm -
Nonstop2h 09m
Deal found 9/16![Delta logo]()
$389
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:55 pm -
1 stop4h 04m
Sun 10/255:00 am -
1 stop4h 21m
Deal found 9/16![American Airlines logo]()
$457
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:35 pm -
1 stop4h 00m
Tue 10/208:30 am -
1 stop4h 00m
Deal found 9/16![Southwest logo]()
$380
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:30 am -
2 stops6h 56m
Tue 10/272:52 pm -
2 stops9h 05m
Deal found 9/20![United Airlines logo]()
$422
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:55 pm -
Nonstop2h 12m
Mon 12/146:56 pm -
Nonstop2h 16m
Deal found 9/16![Delta logo]()
$389
Last-minute flights from Detroit to South CarolinaDiscover last-minute flight deals from Detroit to South Carolina. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to South Carolina. Data last updated September 21, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:59 pm -
1 stop17h 39m
Tue 10/273:00 pm -
1 stop20h 40m
Deal found 9/17![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:59 pm -
1 stop17h 39m
Thu 10/296:45 am -
2 stops29h 22m
Deal found 9/17![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:59 pm -
1 stop17h 39m
Wed 10/286:00 am -
2 stops18h 44m
Deal found 9/17![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:29 pm -
1 stop17h 26m
Thu 10/228:10 pm -
1 stop27h 19m
Deal found 9/19![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:29 pm -
1 stop17h 26m
Thu 10/298:10 pm -
1 stop27h 27m
Deal found 9/16![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:50 pm -
1 stop14h 48m
Tue 10/273:00 pm -
1 stop20h 40m
Deal found 9/17![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:50 pm -
1 stop14h 48m
Thu 10/296:45 am -
2 stops29h 22m
Deal found 9/17![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:50 pm -
1 stop14h 48m
Fri 10/238:58 pm -
1 stop13h 54m
Deal found 9/16![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/243:03 pm -
2 stops17h 35m
Tue 10/273:00 pm -
1 stop20h 40m
Deal found 9/16![Multiple Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:29 pm -
1 stop17h 26m
Wed 10/282:42 pm -
1 stop8h 55m
Deal found 9/17![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:02 pm -
1 stop14h 36m
Sat 10/313:42 pm -
1 stop18h 10m
Deal found 9/19![Multiple Airlines logo]()
$252
This JetBlue deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:39 pm -
1 stop6h 39m
Wed 11/48:44 am -
1 stop8h 05m
Deal found 9/17![JetBlue logo]()
$258
One-way flights from Detroit to South CarolinaSearch for one-way flight options from Detroit to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from Detroit to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Super.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:59 pm -
1 stop11h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Frontier logo]()
$88
This Expedia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:59 pm -
1 stop11h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:34 pm -
1 stop20h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Frontier logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:50 pm -
1 stop14h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Frontier logo]()
$98
This CheapOair deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:07 pm -
1 stop11h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$99
This Super.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:28 pm -
1 stop12h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/161:02 pm -
1 stop19h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:59 pm -
1 stop17h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/142:53 pm -
1 stop17h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:29 pm -
1 stop28h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:35 pm -
1 stop20h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:29 pm -
2 stops17h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$120
Find flight deals from Detroit to South Carolina
Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $222 (Kiwi.com) |
One-way from | $88 (Super.com) |
Popular in | March |
Cheapest in | October |
Average price | $523 |
Good round-trip deal | $379 or less |
Good one-way deal | $233 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Detroit to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitMyrtle Beach
DTW Detroit Metropolitan Wayne County - MYR Myrtle Beach Intl
DTWMYR
Detroit Metropolitan Wayne County
Tue 12/15
6:00 am-1:15 pm
1 stop7h 15m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$121
DetroitCharlotte
DTW Detroit Metropolitan Wayne County - CLT Charlotte Douglas
DTWCLT
Detroit Metropolitan Wayne County
Mon 10/12
12:57 pm-8:37 am
1 stop19h 40m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Tue 11/10
7:46 am-3:14 pm
1 stop7h 28m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$132
DetroitSavannah
DTW Detroit Metropolitan Wayne County - SAV Savannah/Hilton Head
DTWSAV
Detroit Metropolitan Wayne County
Sat 10/31
11:25 am-3:35 pm
1 stop4h 10m
Savannah/Hilton Head
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$133
DetroitCharlotte
DTW Detroit Metropolitan Wayne County - CLT Charlotte Douglas
DTWCLT
Detroit Metropolitan Wayne County
Tue 12/15
5:30 am-10:15 am
1 stop4h 45m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$134
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Tue 11/17
6:55 am-5:25 pm
2 stops10h 30m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$138
DetroitCharlotte
DTW Detroit Metropolitan Wayne County - CLT Charlotte Douglas
DTWCLT
Detroit Metropolitan Wayne County
Sat 11/14
9:05 am-7:35 pm
2 stops10h 30m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
DetroitSavannah
DTW Detroit Metropolitan Wayne County - SAV Savannah/Hilton Head
DTWSAV
Detroit Metropolitan Wayne County
Mon 11/9
7:46 am-2:47 pm
1 stop7h 01m
Savannah/Hilton Head
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$150
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Mon 12/14
9:36 pm-10:36 pm
2 stops25h 00m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$153
DetroitCharlotte
DTW Detroit Metropolitan Wayne County - CLT Charlotte Douglas
DTWCLT
Detroit Metropolitan Wayne County
Thu 12/17
8:20 am-7:25 pm
2 stops11h 05m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$170
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Detroit to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
DTW-CHS
DTW-MYR
DTW-SAV
DTW-CLT
DTW-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to South Carolina
DTT-USSC
DTW-CHS
DTW-MYR
DTW-SAV
DTW-CLT
What is the cheapest month to book a flight from Detroit to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $346). Flying from Detroit to South Carolina in March is currently the most expensive (average of $457). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to SC?
Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 21, 2026.
When flying from Detroit to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 20% versus a flight in the morning.
Weekly flight availability from Detroit to South Carolina
Explore weekly flight availability from Detroit to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 21, 2026.
The most flights from DTT to USSC are scheduled on a Friday (13 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (5 on average).
How much does it cost to fly round-trip from Detroit to South Carolina?
Airfare is below average for this route at the moment.
Detroit to South Carolina flights typically cost between $378 and $543 in October.The cheapest round-trip price found within the last 5 days was $222 on Multiple Airlines (Oct 19-Oct 27).
How far ahead should I book a flight from Detroit to South Carolina?
The best time to book flights from Detroit to South Carolina is 61 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest day to fly from Detroit to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Detroit to South Carolina. Price data was last updated on September 19, 2026.
Travelers seeking maximum savings on their Detroit to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 21, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAmerican Airlines from Detroit to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Detroit to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to South Carolina by cabin class
Find flights from Detroit to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and South Carolina flights
Browse other Detroit and South Carolina flight options. Last updated on September 21, 2026.
Popular flight searches
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Detroit to South Carolina flights
Consider these flights traveling from Detroit to South Carolina.
Top 4 airlines flying from Detroit to South Carolina
Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$235 | Average$403 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$418 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$283 | Average$358 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$298 | Average$443 | FlexibilityNo cancel fee | On-timeN/A |