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$41+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from Detroit to South Carolina

Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated August 20, 2025.

Round-trip from

$94
(FlightHub)

One-way from

$41
(FlightHub)

Popular in

December

Cheapest in

August

Average price

$152

Good round-trip deal

$126 or less

Good one-way deal

$64 or less
From Detroit Metropolitan Wayne County to South Carolina
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One-way flight from Detroit Metropolitan Wayne County to South Carolina
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Highest demand for flights based on searches. 21% potential increase in price ($63 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to South Carolina.
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Price to beat on a one-way flight from Detroit Metropolitan Wayne County to South Carolina.
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Find flight deals from Detroit to South Carolina

Cheapest flights from Detroit to South Carolina
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/139:12 amDTW - SAV
1 stop5h 03mSpirit Airlines
Sat 9/203:15 pmSAV - DTW
1 stop7h 14mSpirit Airlines
Deal found 8/19$94
This Cheapflightsfares deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/109:12 amDTW - CLT
1 stop5h 17mSpirit Airlines
Sun 9/142:39 pmCLT - DTW
Nonstop1h 47mSpirit Airlines
Deal found 8/19$116
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/173:44 pmDTW - SAV
Nonstop2h 06mSpirit Airlines
Mon 10/206:47 pmSAV - DTW
Nonstop2h 11mSpirit Airlines
Deal found 8/19$117
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/273:44 pmDTW - SAV
Nonstop2h 06mSpirit Airlines
Mon 11/36:47 pmSAV - DTW
Nonstop2h 11mSpirit Airlines
Deal found 8/19$118
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2611:56 amDTW - CLT
Nonstop1h 48mSpirit Airlines
Sun 9/282:39 pmCLT - DTW
Nonstop1h 47mSpirit Airlines
Deal found 8/18$118
This Priceline deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:56 amDTW - CLT
Nonstop1h 48mSpirit Airlines
Sun 10/52:35 pmCLT - DTW
Nonstop1h 45mSpirit Airlines
Deal found 8/18$120
This Cheapflightsfares deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/89:12 amDTW - CLT
1 stop5h 17mSpirit Airlines
Tue 9/169:10 amCLT - DTW
1 stop4h 49mSpirit Airlines
Deal found 8/19$122
This Cheapflightsfares deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/811:56 amDTW - CLT
Nonstop1h 48mSpirit Airlines
Tue 9/99:10 amCLT - DTW
1 stop6h 44mSpirit Airlines
Deal found 8/18$123
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/36:15 amDTW - CLT
1 stop7h 50mSpirit Airlines
Mon 9/89:10 amCLT - DTW
1 stop4h 49mSpirit Airlines
Deal found 8/20$125
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/63:44 pmDTW - SAV
Nonstop2h 06mSpirit Airlines
Fri 10/106:47 pmSAV - DTW
Nonstop2h 11mSpirit Airlines
Deal found 8/19$127
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/103:44 pmDTW - SAV
Nonstop2h 06mSpirit Airlines
Fri 10/176:47 pmSAV - DTW
Nonstop2h 11mSpirit Airlines
Deal found 8/18$128
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2511:56 amDTW - CLT
Nonstop1h 48mSpirit Airlines
Fri 9/262:39 pmCLT - DTW
Nonstop1h 47mSpirit Airlines
Deal found 8/18$128

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to South Carolina that are best for you.

Fly from

Detroit

Fly to

South Carolina

Route

Depart

Return

Price

DetroitSavannah

DTW - SAV

DTWSAV

Detroit Metropolitan Wayne County

Sat 9/13

9:12 am-2:15 pm

1 stop5h 03m

Savannah/Hilton Head

Sat 9/20

3:15 pm-10:29 pm

1 stop7h 14m

$94

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Wed 9/10

9:12 am-2:29 pm

1 stop5h 17m

Charlotte Douglas

Sun 9/14

2:39 pm-4:26 pm

Nonstop1h 47m

$116

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Sun 9/14

11:56 am-1:44 pm

Nonstop1h 48m

Charlotte Douglas

Wed 9/17

9:10 am-3:54 pm

1 stop6h 44m

$116

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Wed 9/10

9:12 am-2:29 pm

1 stop5h 17m

Charlotte Douglas

Fri 9/12

2:39 pm-4:26 pm

Nonstop1h 47m

$116

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Mon 9/15

11:56 am-1:44 pm

Nonstop1h 48m

Charlotte Douglas

Wed 9/17

9:10 am-1:59 pm

1 stop4h 49m

$116

DetroitSavannah

DTW - SAV

DTWSAV

Detroit Metropolitan Wayne County

Fri 10/31

3:44 pm-5:50 pm

Nonstop2h 06m

Savannah/Hilton Head

Mon 11/3

6:47 pm-8:58 pm

Nonstop2h 11m

$117

DetroitSavannah

DTW - SAV

DTWSAV

Detroit Metropolitan Wayne County

Fri 10/17

3:44 pm-5:50 pm

Nonstop2h 06m

Savannah/Hilton Head

Mon 10/20

6:47 pm-8:58 pm

Nonstop2h 11m

$117

DetroitSavannah

DTW - SAV

DTWSAV

Detroit Metropolitan Wayne County

Mon 10/20

3:44 pm-5:50 pm

Nonstop2h 06m

Savannah/Hilton Head

Fri 10/24

6:47 pm-8:58 pm

Nonstop2h 11m

$118

DetroitSavannah

DTW - SAV

DTWSAV

Detroit Metropolitan Wayne County

Mon 10/27

3:44 pm-5:50 pm

Nonstop2h 06m

Savannah/Hilton Head

Mon 11/3

6:47 pm-8:58 pm

Nonstop2h 11m

$118

DetroitSavannah

DTW - SAV

DTWSAV

Detroit Metropolitan Wayne County

Fri 11/7

3:10 pm-5:18 pm

Nonstop2h 08m

Savannah/Hilton Head

Mon 11/10

6:13 pm-8:24 pm

Nonstop2h 11m

$118

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/20

Showing 1-10 of 60 results
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Best time to book a flight from Detroit to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to South Carolina

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South Carolina (average of $217). Flying from Detroit Metropolitan Wayne County Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to SC?

Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

When flying from Detroit Metropolitan Wayne County Airport to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Detroit Metropolitan Wayne County Airport to South Carolina

Explore weekly flight availability from Detroit to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 20, 2025.

The most flights from DTW to USSC are scheduled on a Monday (13 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (6 on average).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 20, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Detroit Metropolitan Wayne County Airport to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,982 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Spirit Airlines
6.3
Okay
8,039 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Comfort

8.0

Entertainment

7.5

Crew

8.6

Food

7.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to South Carolina?

    If you book a flight to South Carolina from Detroit, you will be flying from Detroit Metropolitan Wayne County, which is the city’s only airport. Detroit Metropolitan Wayne County (DTW) is located 17.3 mi from the center of Detroit.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to South Carolina?

    Spirit Airlines, Delta, and American Airlines can get you from Detroit Metropolitan Wayne County Airport to South Carolina in just under 2h 07m. Your travel time can differ by up to 3h 25m. The distance from Detroit Metropolitan Wayne County Airport to South Carolina is about 669 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Detroit Metropolitan Wayne County Airport to South Carolina?

    When deciding which route to take from Detroit Metropolitan Wayne County Airport to South Carolina consider Detroit Metropolitan Wayne County - Charlotte Douglas, Detroit Metropolitan Wayne County - Savannah/Hilton Head or Detroit Metropolitan Wayne County - Myrtle Beach Intl as they are the most popular.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to South Carolina?

    The top 3 most reliable airlines when flying from Detroit Metropolitan Wayne County Airport to South Carolina are Spirit Airlines (96%), WestJet (80%) and Delta (70%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to South Carolina?

    Looking for the cheapest flight from Detroit Metropolitan Wayne County Airport to South Carolina? While on average our users pay $210, our data indicates the cheapest price to be $43. The most popular route (Detroit Metropolitan Wayne County - Charlotte Douglas), is priced around $86.

  • Can I find deals for flights from Detroit to South Carolina that include hotel bookings?

    Yes. In addition to deals on Detroit to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to South Carolina.

  • Can I find deals for business class flights from Detroit to South Carolina?

    Yes. Cheapflights offers flight deals from Detroit to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South Carolina (average of $217). Flying from Detroit Metropolitan Wayne County Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Detroit to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Detroit to South Carolina

Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$66Average$165FlexibilityNo cancel feeOn-time65%
DeltaCheapest$159Average$378FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$180Average$362FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$231Average$365FlexibilityNo cancel feeOn-time63%

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