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South Carolina

$51+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
nov. 13 — nov. 201
jue. 11/13
jue. 11/20
1 adult, Economy
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Cheap flight deals from Detroit to South Carolina

Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated octubre 14, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$138
(Cheapflightsfares)

One-way from

$51
(Cheapflightsfares)

Popular in

November

Cheapest in

August

Average price

$248

Good round-trip deal

$248 or less

Good one-way deal

$90 or less
Provider with most accurate pricing for Detroit (DTT)-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Detroit (DTT)-Myrtle Beach Intl flights.
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From Detroit Metropolitan Wayne County to South Carolina
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One-way flight from Detroit Metropolitan Wayne County to South Carolina
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Highest demand for flights based on searches. 21% potential increase in price ($68 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to South Carolina.
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Price to beat on a one-way flight from Detroit Metropolitan Wayne County to South Carolina.
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Find flight deals from Detroit to South Carolina

Cheapest flights from Detroit to South Carolina
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 14, 2025.

This Priceline deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/133:12 pmDTW - CLT
1 stop6h 56mSpirit Airlines
sáb. 11/156:00 amCLT - DTW
1 stop7h 04mSpirit Airlines
Deal found 10/14$137
This Cheapflightsfares deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/63:12 pmDTW - CLT
1 stop6h 56mSpirit Airlines
mar. 11/116:00 amCLT - DTW
1 stop4h 58mSpirit Airlines
Deal found 10/14$138
This Cheapflightsfares deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/113:19 pmDTW - CLT
1 stop8h 03mSpirit Airlines
sáb. 12/136:25 amCLT - DTW
Nonstop1h 48mSpirit Airlines
Deal found 10/13$139
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/59:39 pmDTW - CLT
1 stop21h 03mMultiple Airlines
sáb. 11/84:55 pmCLT - DTW
1 stop7h 12mMultiple Airlines
Deal found 10/14$143
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/63:12 pmDTW - CLT
1 stop6h 56mSpirit Airlines
sáb. 11/89:53 amCLT - DTW
1 stop5h 22mSpirit Airlines
Deal found 10/14$145
This Cheapflightsfares deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/33:12 pmDTW - CLT
1 stop6h 56mSpirit Airlines
jue. 11/66:00 amCLT - DTW
1 stop4h 58mSpirit Airlines
Deal found 10/13$148
This Cheapflightsfares deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/316:18 pmDTW - CLT
1 stop4h 43mSpirit Airlines
mar. 11/46:00 amCLT - DTW
1 stop4h 58mSpirit Airlines
Deal found 10/14$150
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/1210:42 amDTW - CLT
1 stop9h 16mSpirit Airlines
dom. 11/166:11 pmCLT - DTW
Nonstop1h 45mSpirit Airlines
Deal found 10/14$151
This Cheapflightsfares deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/63:12 pmDTW - CLT
1 stop6h 56mSpirit Airlines
dom. 11/96:11 pmCLT - DTW
Nonstop1h 45mSpirit Airlines
Deal found 10/12$154
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/63:12 pmDTW - CLT
1 stop6h 56mSpirit Airlines
lun. 11/106:00 amCLT - DTW
1 stop4h 58mSpirit Airlines
Deal found 10/14$158
This Priceline deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/269:40 amDTW - MYR
Nonstop1h 56mSpirit Airlines
jue. 10/3012:31 pmMYR - DTW
Nonstop1h 58mSpirit Airlines
Deal found 10/12$176
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/17:58 pmDTW - CHS
1 stop12h 58mSpirit Airlines
vie. 11/146:11 pmCHS - DTW
1 stop5h 56mSpirit Airlines
Deal found 10/14$185

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 14, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to South Carolina that are best for you.

Fly from

Detroit

Fly to

South Carolina

Route

Depart

Return

Price

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

jue. 11/6

3:24 pm-5:16 pm

Nonstop1h 52m

Charlotte Douglas

dom. 11/9

6:11 pm-7:56 pm

Nonstop1h 45m

$159

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

mar. 11/11

2:22 pm-4:10 pm

Nonstop1h 48m

Charlotte Douglas

sáb. 11/15

5:14 pm-7:07 pm

Nonstop1h 53m

$161

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

mié. 10/22

5:23 pm-11:29 pm

1 stop6h 06m

Charlotte Douglas

vie. 10/24

12:05 pm-6:01 pm

1 stop5h 56m

$176

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

lun. 12/8

8:02 pm-9:55 pm

Nonstop1h 53m

Charlotte Douglas

sáb. 12/13

5:14 pm-7:07 pm

Nonstop1h 53m

$181

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

vie. 1/9

2:00 pm-3:51 pm

Nonstop1h 51m

Charlotte Douglas

lun. 1/12

11:35 am-1:32 pm

Nonstop1h 57m

$181

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

jue. 11/6

7:05 am-8:54 am

Nonstop1h 49m

Charlotte Douglas

mar. 11/11

9:27 am-11:22 am

Nonstop1h 55m

$191

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

sáb. 11/1

10:23 am-12:11 pm

Nonstop1h 48m

Charlotte Douglas

sáb. 11/8

5:25 pm-7:15 pm

Nonstop1h 50m

$196

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

vie. 10/31

2:08 pm-3:55 pm

Nonstop1h 47m

Charlotte Douglas

mar. 11/4

12:56 pm-2:40 pm

Nonstop1h 44m

$207

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

vie. 12/5

2:22 pm-4:13 pm

Nonstop1h 51m

Charlotte Douglas

lun. 12/8

5:11 pm-7:04 pm

Nonstop1h 53m

$211

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

vie. 12/5

4:00 pm-6:16 pm

Nonstop2h 16m

Charleston

lun. 12/8

6:56 pm-9:17 pm

Nonstop2h 21m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/12

Showing 1-10 of 60 results
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Best time to book a flight from Detroit to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to South Carolina

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South Carolina (average of $91). Flying from Detroit Metropolitan Wayne County Airport to South Carolina in December is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to SC?

Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 14, 2025.

One of the essential ways to save on airfare from Detroit Metropolitan Wayne County Airport to South Carolina is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 17% on airfare.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Detroit to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Detroit Metropolitan Wayne County Airport to South Carolina

Explore weekly flight availability from Detroit to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated octubre 14, 2025.

The most flights from DTW to USSC are scheduled on a Monday (12 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated octubre 14, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Detroit Metropolitan Wayne County Airport to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,975 reviews
Southwest
8.0
Very good
4,238 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,042 reviews
Southwest
8.0
Very good
4,238 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,096 reviews
Southwest
8.0
Very good
4,238 reviews

Entertainment

7.5

Boarding

8.1

Overall

8.0

Food

7.0

Crew

8.6

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to South Carolina?

    If you book a flight to South Carolina from Detroit, you will be flying from Detroit Metropolitan Wayne County, which is the city’s only airport. Detroit Metropolitan Wayne County (DTW) is located 17.3 mi from the center of Detroit.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to South Carolina?

    Spirit Airlines, Delta, and American Airlines can get you from Detroit Metropolitan Wayne County Airport to South Carolina in just under 1h 48m. Your travel time can differ by up to 4h 26m. The distance from Detroit Metropolitan Wayne County Airport to South Carolina is about 500 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Detroit Metropolitan Wayne County Airport to South Carolina?

    When deciding which route to take from Detroit Metropolitan Wayne County Airport to South Carolina consider Detroit Metropolitan Wayne County - Charlotte Douglas, Detroit Metropolitan Wayne County - Savannah/Hilton Head or Detroit Metropolitan Wayne County - Charleston as they are the most popular.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to South Carolina?

    The top 3 most reliable airlines when flying from Detroit Metropolitan Wayne County Airport to South Carolina are Spirit Airlines (87%), WestJet (87%) and Delta (79%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to South Carolina?

    Looking for the cheapest flight from Detroit Metropolitan Wayne County Airport to South Carolina? While on average our users pay $331, our data indicates the cheapest price to be $158. The most popular route (Detroit Metropolitan Wayne County - Charlotte Douglas), is priced around $126.

  • Can I find deals for flights from Detroit to South Carolina that include hotel bookings?

    Yes. In addition to deals on Detroit to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to South Carolina.

  • Can I find deals for business class flights from Detroit to South Carolina?

    Yes. Cheapflights offers flight deals from Detroit to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South Carolina (average of $91). Flying from Detroit Metropolitan Wayne County Airport to South Carolina in December is currently the most expensive (average of $186). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Detroit to South Carolina

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Top 4 airlines flying from Detroit to South Carolina

Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$76Average$174FlexibilityNo cancel feeOn-time65%
DeltaCheapest$159Average$384FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$352FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$231Average$373FlexibilityNo cancel feeOn-time63%

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