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South Carolina

$58+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — CHS
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Detroit to South Carolina

Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated September 15, 2025.

Round-trip from

$118
(Kiwi.com)

One-way from

$58
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$218

Good round-trip deal

$159 or less

Good one-way deal

$100 or less
From Detroit Metropolitan Wayne County to South Carolina
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One-way flight from Detroit Metropolitan Wayne County to South Carolina
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Highest demand for flights based on searches. 21% potential increase in price ($66 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to South Carolina.
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Price to beat on a one-way flight from Detroit Metropolitan Wayne County to South Carolina.
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Find flight deals from Detroit to South Carolina

Cheapest flights from Detroit to South Carolina
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:20 pmDTW - CLT
1 stop6h 16mSpirit Airlines
Tue 10/76:00 amCLT - DTW
1 stop9h 14mSpirit Airlines
Deal found 9/13$118
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/155:23 pmDTW - CLT
1 stop6h 06mSpirit Airlines
Thu 10/166:00 amCLT - DTW
1 stop9h 14mSpirit Airlines
Deal found 9/14$126
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1011:46 amDTW - CLT
Nonstop1h 54mSpirit Airlines
Wed 10/156:00 amCLT - DTW
1 stop9h 14mSpirit Airlines
Deal found 9/14$127
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/215:23 pmDTW - CLT
1 stop6h 06mSpirit Airlines
Sat 10/2512:00 pmCLT - DTW
1 stop7h 10mSpirit Airlines
Deal found 9/13$128
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:20 pmDTW - CLT
1 stop6h 16mSpirit Airlines
Tue 10/76:00 amCLT - DTW
1 stop9h 14mSpirit Airlines
Deal found 9/13$129
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:20 pmDTW - CLT
1 stop6h 16mSpirit Airlines
Fri 10/31:48 pmCLT - DTW
1 stop8h 52mSpirit Airlines
Deal found 9/13$131
This Booking.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:20 pmDTW - CLT
1 stop6h 16mSpirit Airlines
Tue 10/76:00 amCLT - DTW
1 stop9h 14mSpirit Airlines
Deal found 9/13$132
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:20 pmDTW - CLT
1 stop6h 16mSpirit Airlines
Wed 10/86:00 amCLT - DTW
1 stop9h 14mSpirit Airlines
Deal found 9/13$133
This Trip.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:20 pmDTW - CLT
1 stop6h 16mMultiple Airlines
Sat 10/42:01 pmCLT - DTW
1 stop18h 43mMultiple Airlines
Deal found 9/14$134
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/75:23 pmDTW - CLT
1 stop6h 06mSpirit Airlines
Fri 10/102:35 pmCLT - DTW
Nonstop1h 45mSpirit Airlines
Deal found 9/13$135
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/305:20 pmDTW - CLT
1 stop6h 16mSpirit Airlines
Mon 10/62:35 pmCLT - DTW
Nonstop1h 45mSpirit Airlines
Deal found 9/13$138
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/511:46 amDTW - CLT
Nonstop1h 54mSpirit Airlines
Wed 10/86:00 amCLT - DTW
1 stop9h 14mSpirit Airlines
Deal found 9/13$139

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to South Carolina that are best for you.

Fly from

Detroit

Fly to

South Carolina

Route

Depart

Return

Price

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Wed 10/15

10:23 am-12:11 pm

Nonstop1h 48m

Charlotte Douglas

Tue 10/21

6:00 am-7:50 am

Nonstop1h 50m

$151

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Sat 10/18

10:23 am-12:11 pm

Nonstop1h 48m

Charlotte Douglas

Sat 10/25

5:25 pm-7:15 pm

Nonstop1h 50m

$151

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Thu 11/6

10:00 am-11:56 am

Nonstop1h 56m

Myrtle Beach Intl

Sun 11/9

1:01 pm-2:57 pm

Nonstop1h 56m

$156

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Sat 10/11

7:50 pm-9:35 pm

Nonstop1h 45m

Charlotte Douglas

Tue 10/14

5:25 pm-7:15 pm

Nonstop1h 50m

$161

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Wed 10/8

10:23 am-12:11 pm

Nonstop1h 48m

Charlotte Douglas

Sat 10/11

12:56 pm-2:40 pm

Nonstop1h 44m

$171

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Tue 10/7

5:45 am-11:00 am

1 stop5h 15m

Charlotte Douglas

Sat 10/11

6:00 am-7:50 am

Nonstop1h 50m

$181

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Sat 10/4

9:35 pm-11:17 pm

Nonstop1h 42m

Charlotte Douglas

Wed 10/8

8:16 am-12:56 pm

1 stop4h 40m

$181

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Sat 10/18

2:08 pm-3:55 pm

Nonstop1h 47m

Charlotte Douglas

Thu 10/23

6:00 am-7:50 am

Nonstop1h 50m

$181

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Thu 11/6

2:08 pm-3:55 pm

Nonstop1h 47m

Charlotte Douglas

Tue 11/11

12:44 pm-2:34 pm

Nonstop1h 50m

$181

DetroitMyrtle Beach

DTW - MYR

DTWMYR

Detroit Metropolitan Wayne County

Mon 10/6

4:55 pm-12:11 am

1 stop7h 16m

Myrtle Beach Intl

Thu 10/9

12:31 pm-2:29 pm

Nonstop1h 58m

$191

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 60 results
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Best time to book a flight from Detroit to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to South Carolina

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South Carolina (average of $217). Flying from Detroit Metropolitan Wayne County Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to SC?

Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from Detroit Metropolitan Wayne County Airport to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Detroit Metropolitan Wayne County Airport to South Carolina

Explore weekly flight availability from Detroit to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 15, 2025.

The most flights from DTW to USSC are scheduled on a Friday (12 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (9 on average).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 15, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Detroit Metropolitan Wayne County Airport to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,245 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,245 reviews
Southwest
8.0
Very good
4,245 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,956 reviews
Southwest
8.0
Very good
4,245 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,245 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,016 reviews
Southwest
8.0
Very good
4,245 reviews

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to South Carolina?

    If you book a flight to South Carolina from Detroit, you will be flying from Detroit Metropolitan Wayne County, which is the city’s only airport. Detroit Metropolitan Wayne County (DTW) is located 17.3 mi from the center of Detroit.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to South Carolina?

    Delta, Spirit Airlines, and Southwest can get you from Detroit Metropolitan Wayne County Airport to South Carolina in just under 1h 48m. Your travel time can differ by up to 5h 28m. The distance from Detroit Metropolitan Wayne County Airport to South Carolina is about 500 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Detroit Metropolitan Wayne County Airport to South Carolina one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $64. Southwest flights start at $73 while deals on JetBlue start at $81 one-way.

  • What are the most popular routes from Detroit Metropolitan Wayne County Airport to South Carolina?

    When deciding which route to take from Detroit Metropolitan Wayne County Airport to South Carolina consider Detroit Metropolitan Wayne County - Charlotte Douglas, Detroit Metropolitan Wayne County - Charleston or Detroit Metropolitan Wayne County - Savannah/Hilton Head as they are the most popular.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to South Carolina?

    The top 3 most reliable airlines when flying from Detroit Metropolitan Wayne County Airport to South Carolina are Spirit Airlines (95%), Aeromexico (81%) and WestJet (79%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to South Carolina?

    Looking for the cheapest flight from Detroit Metropolitan Wayne County Airport to South Carolina? While on average our users pay $293, our data indicates the cheapest price to be $128. The most popular route (Detroit Metropolitan Wayne County - Charlotte Douglas), is priced around $131.

  • Can I find deals for flights from Detroit to South Carolina that include hotel bookings?

    Yes. In addition to deals on Detroit to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to South Carolina.

  • Can I find deals for business class flights from Detroit to South Carolina?

    Yes. Cheapflights offers flight deals from Detroit to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South Carolina (average of $217). Flying from Detroit Metropolitan Wayne County Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Detroit to South Carolina

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Top 4 airlines flying from Detroit to South Carolina

Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$70Average$171FlexibilityNo cancel feeOn-time65%
DeltaCheapest$159Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$187Average$358FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$231Average$364FlexibilityNo cancel feeOn-time63%

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