$53+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Detroit to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to South Carolina
Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated June 12, 2025.
Round-trip from | $121 (Kiwi.com) |
|---|---|
One-way from | $53 (FlightHub) |
Popular in | December |
Cheapest in | October |
Average price | $236 |
Good round-trip deal | $145 or less |
Good one-way deal | $64 or less |
Find flight deals from Detroit to South Carolina
Cheapest flights from Detroit to South CarolinaExplore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Cheapflightsfares deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This FlightHub deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
DetroitMyrtle Beach
DTW - MYR
DTWMYR
Detroit Metropolitan Wayne County
Tue 8/12
6:05 am-7:39 am
Nonstop1h 34m
Myrtle Beach Intl
Sun 8/17
12:18 pm-2:12 pm
Nonstop1h 54m
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Thu 8/7
6:10 am-10:02 am
1 stop3h 52m
Charlotte Douglas
Mon 8/11
6:29 pm-8:17 pm
Nonstop1h 48m
DetroitCharleston
DTW - CHS
DTWCHS
Detroit Metropolitan Wayne County
Sat 7/5
2:20 pm-10:29 pm
1 stop8h 09m
Charleston
Thu 7/10
10:53 am-12:55 pm
Nonstop2h 02m
DetroitMyrtle Beach
DTW - MYR
DTWMYR
Detroit Metropolitan Wayne County
Fri 8/1
12:43 pm-12:21 pm
1 stop23h 38m
Myrtle Beach Intl
Mon 8/4
5:57 pm-8:01 pm
Nonstop2h 04m
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Sat 9/20
9:15 pm-11:04 pm
Nonstop1h 49m
Charlotte Douglas
Thu 9/25
9:35 am-11:32 am
Nonstop1h 57m
DetroitColumbia
DTW - CAE
DTWCAE
Detroit Metropolitan Wayne County
Sat 9/6
5:40 am-1:21 pm
1 stop7h 41m
Columbia Metropolitan
Tue 9/9
11:57 am-9:42 pm
1 stop9h 45m
DetroitMyrtle Beach
DTW - MYR
DTWMYR
Detroit Metropolitan Wayne County
Tue 7/8
8:40 am-10:34 am
Nonstop1h 54m
Myrtle Beach Intl
Tue 7/15
11:29 am-1:25 pm
Nonstop1h 56m
DetroitCharleston
DTW - CHS
DTWCHS
Detroit Metropolitan Wayne County
Sat 8/30
3:50 pm-5:58 pm
Nonstop2h 08m
Charleston
Wed 9/3
11:20 am-1:21 pm
Nonstop2h 01m
DetroitMyrtle Beach
DTW - MYR
DTWMYR
Detroit Metropolitan Wayne County
Sun 6/15
10:05 am-3:27 pm
1 stop5h 22m
Myrtle Beach Intl
Fri 6/20
6:14 pm-10:29 pm
1 stop4h 15m
DetroitColumbia
DTW - CAE
DTWCAE
Detroit Metropolitan Wayne County
Thu 7/17
6:30 am-2:18 pm
1 stop7h 48m
Columbia Metropolitan
Tue 7/22
1:24 pm-9:11 pm
1 stop7h 47m
Best time to book a flight from Detroit to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to South Carolina
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to South Carolina (average of $217). Flying from Detroit Metropolitan Wayne County Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTW to SC?
Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.
When flying from Detroit Metropolitan Wayne County Airport to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from Detroit Metropolitan Wayne County Airport to South Carolina
Explore weekly flight availability from Detroit to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 12, 2025.
The most flights from DTW to USSC are scheduled on a Monday (13 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (7 on average).
Rainfall in South Carolina by month
Plan your trip to South Carolina by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.
Temperature in South Carolina by month
Plan your trip to South Carolina by taking into account the average temperature totals by month.
If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 12, 2025.
See what other customers who have flown with Southwest, Delta and United Airlines from Detroit to South Carolina have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
Food
Crew
Comfort
Overall
Entertainment
Reviews
John,May 2025
PVD - BNA
Boarding
Food
Crew
Comfort
Overall
Entertainment
Reviews
John,May 2025
PVD - BNA
Boarding
Food
Crew
Comfort
Overall
Entertainment
Reviews
John,May 2025
PVD - BNA
Boarding
Food
Crew
Comfort
Overall
Entertainment
Reviews
John,May 2025
PVD - BNA
Boarding
Food
Crew
Comfort
Overall
Entertainment
Reviews
John,May 2025
PVD - BNA
Boarding
Food
Crew
Comfort
Overall
Entertainment
Reviews
John,May 2025
PVD - BNA
Related info for your journey
Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Detroit to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from Detroit to South Carolina
Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$68 | Average$169 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$158 | Average$376 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$178 | Average$362 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$237 | Average$374 | FlexibilityNo cancel fee | On-time63% |