$77+ Cheap flights from Detroit (DTT) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — CHS
Jul 4 — Jul 111
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to South Carolina with Cheapflights
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Cheapest flights from Detroit to South CarolinaExplore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 4, 2026.
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:00 am
DTW
- SAV
1 stop6h 55m
Multiple Airlines
Sat 8/2212:19 pm
SAV
- DTW
1 stop24h 48m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$204
This Super.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:30 am
DTW
- CHS
1 stop8h 53m
JetBlue
Tue 7/285:19 pm
CHS
- DTW
1 stop5h 26m
JetBlue
Deal found 6/3![JetBlue logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:00 am
DTW
- SAV
1 stop6h 55m
Multiple Airlines
Thu 9/310:05 am
SAV
- DTW
1 stop27h 02m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:00 am
DTW
- GSP
1 stop20h 57m
Multiple Airlines
Mon 8/244:55 pm
GSP
- DTW
1 stop20h 12m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- SAV
1 stop28h 43m
Multiple Airlines
Wed 7/2912:19 pm
SAV
- DTW
1 stop24h 36m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- SAV
1 stop8h 43m
Multiple Airlines
Sun 7/2610:05 am
SAV
- DTW
1 stop26h 50m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$232
This Super.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:30 am
DTW
- CHS
1 stop5h 37m
JetBlue
Tue 7/72:15 pm
CHS
- DTW
1 stop8h 30m
JetBlue
Deal found 6/3![JetBlue logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- SAV
1 stop28h 43m
Multiple Airlines
Thu 7/3010:05 am
SAV
- DTW
1 stop26h 50m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- GSP
1 stop22h 45m
Multiple Airlines
Sun 7/268:37 am
GSP
- DTW
1 stop28h 18m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:10 am
DTW
- GSP
2 stops25h 18m
Multiple Airlines
Mon 8/174:57 pm
GSP
- DTW
1 stop20h 10m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:00 am
DTW
- CHS
1 stop29h 03m
Multiple Airlines
Thu 9/2410:05 pm
CHS
- DTW
1 stop15h 02m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:00 am
DTW
- SAV
1 stop26h 00m
Multiple Airlines
Thu 9/249:15 am
SAV
- DTW
1 stop27h 52m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$254
Best flights from Detroit to South CarolinaDiscover carefully curated flight deals from Detroit to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 4, 2026.
Discover carefully curated flight deals from Detroit to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 4, 2026.
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:41 am
DTW
- MYR
Nonstop1h 57m
Delta
Wed 8/2611:33 am
MYR
- DTW
Nonstop1h 57m
Delta
Deal found 5/30![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:13 am
DTW
- CAE
1 stop4h 03m
United Airlines
Sat 7/410:31 am
CAE
- DTW
1 stop4h 03m
United Airlines
Deal found 6/1![United Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
DTW
- SAV
2 stops10h 25m
Southwest
Tue 9/81:10 pm
SAV
- DTW
2 stops8h 40m
Southwest
Deal found 6/3![Southwest logo]()
$329
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
DTW
- AGS
1 stop6h 18m
American Airlines
Sat 8/155:40 pm
AGS
- DTW
1 stop5h 57m
American Airlines
Deal found 6/2![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:20 am
DTW
- SAV
1 stop3h 56m
Delta
Tue 8/256:11 pm
SAV
- DTW
Nonstop2h 17m
Delta
Deal found 6/3![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:00 am
DTW
- CAE
1 stop4h 39m
United Airlines
Wed 7/82:51 pm
CAE
- DTW
2 stops8h 40m
United Airlines
Deal found 6/1![United Airlines logo]()
$352
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:25 am
DTW
- HHH
1 stop7h 07m
Delta
Wed 8/264:15 pm
HHH
- DTW
1 stop7h 06m
Delta
Deal found 6/3![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:50 pm
DTW
- MYR
1 stop3h 50m
Southwest
Tue 9/1511:00 am
MYR
- DTW
2 stops10h 15m
Southwest
Deal found 6/3![Southwest logo]()
$364
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:11 pm
DTW
- AGS
1 stop5h 06m
American Airlines
Tue 7/76:30 am
AGS
- DTW
1 stop6h 16m
American Airlines
Deal found 6/2![American Airlines logo]()
$375
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:25 am
DTW
- MYR
2 stops7h 25m
Southwest
Thu 10/18:15 pm
MYR
- DTW
1 stop3h 40m
Southwest
Deal found 6/2![Southwest logo]()
$364
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:37 am
DTW
- CLT
Nonstop1h 49m
Delta
Tue 7/77:00 am
CLT
- DTW
1 stop7h 51m
Delta
Deal found 6/4![Delta logo]()
$333
This United Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:20 am
DTW
- CAE
2 stops11h 08m
United Airlines
Sun 8/307:54 pm
CAE
- DTW
1 stop4h 05m
United Airlines
Deal found 5/30![United Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:00 am
DTW
- AGS
1 stop5h 18m
American Airlines
Mon 7/66:31 pm
AGS
- DTW
1 stop6h 10m
American Airlines
Deal found 6/1![American Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:25 pm
DTW
- MYR
1 stop6h 50m
Southwest
Sat 10/3111:50 am
MYR
- DTW
2 stops7h 00m
Southwest
Deal found 6/1![Southwest logo]()
$364
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1810:00 am
DTW
- MYR
Nonstop1h 54m
Delta
Fri 9/2512:50 pm
MYR
- DTW
Nonstop1h 57m
Delta
Deal found 6/2![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:17 pm
DTW
- AGS
1 stop5h 52m
American Airlines
Sun 7/125:00 am
AGS
- DTW
1 stop4h 17m
American Airlines
Deal found 5/31![American Airlines logo]()
$395
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:55 am
DTW
- SAV
1 stop4h 25m
Southwest
Thu 7/165:25 pm
SAV
- DTW
2 stops6h 45m
Southwest
Deal found 6/3![Southwest logo]()
$364
This United Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:50 am
DTW
- HHH
1 stop5h 31m
United Airlines
Tue 6/233:05 pm
HHH
- DTW
1 stop7h 14m
United Airlines
Deal found 6/2![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:45 am
DTW
- SAV
Nonstop2h 07m
Delta
Mon 7/276:10 pm
SAV
- DTW
Nonstop2h 17m
Delta
Deal found 6/3![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:39 am
DTW
- AGS
2 stops7h 35m
American Airlines
Tue 8/185:40 pm
AGS
- DTW
1 stop5h 52m
American Airlines
Deal found 6/1![American Airlines logo]()
$400
This Southwest deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:35 am
DTW
- SAV
2 stops7h 05m
Southwest
Tue 7/146:45 am
SAV
- DTW
1 stop6h 00m
Southwest
Deal found 5/31![Southwest logo]()
$364
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:25 pm
DTW
- AGS
1 stop5h 05m
Delta
Tue 8/187:15 pm
AGS
- DTW
1 stop5h 44m
Delta
Deal found 5/30![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:13 am
DTW
- CAE
1 stop4h 03m
United Airlines
Tue 7/72:51 pm
CAE
- DTW
2 stops8h 40m
United Airlines
Deal found 6/3![United Airlines logo]()
$442
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:35 am
DTW
- CHS
2 stops7h 35m
Southwest
Fri 7/174:45 pm
CHS
- DTW
2 stops7h 25m
Southwest
Deal found 6/3![Southwest logo]()
$369
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:10 pm
DTW
- CHS
Nonstop2h 14m
Delta
Mon 8/176:43 pm
CHS
- DTW
Nonstop2h 02m
Delta
Deal found 6/2![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:00 am
DTW
- HHH
1 stop4h 17m
American Airlines
Sat 8/293:27 pm
HHH
- DTW
2 stops9h 25m
American Airlines
Deal found 5/31![American Airlines logo]()
$435
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:45 am
DTW
- CHS
2 stops11h 00m
Southwest
Sun 8/162:05 pm
CHS
- DTW
2 stops7h 25m
Southwest
Deal found 6/1![Southwest logo]()
$369
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:31 pm
DTW
- CHS
Nonstop2h 13m
Delta
Sun 7/126:43 pm
CHS
- DTW
Nonstop2h 02m
Delta
Deal found 6/3![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
DTW
- CAE
2 stops7h 46m
United Airlines
Sun 6/147:45 pm
CAE
- DTW
1 stop4h 06m
United Airlines
Deal found 6/3![United Airlines logo]()
$485
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:00 am
DTW
- HHH
1 stop5h 26m
American Airlines
Tue 6/2311:40 am
HHH
- DTW
2 stops8h 46m
American Airlines
Deal found 6/3![American Airlines logo]()
$443
Last-minute flights from Detroit to South CarolinaDiscover last-minute flight deals from Detroit to South Carolina. Data last updated June 4, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to South Carolina. Data last updated June 4, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:30 am
DTW
- CHS
1 stop5h 37m
JetBlue
Tue 7/72:15 pm
CHS
- DTW
1 stop8h 30m
JetBlue
Deal found 6/3![JetBlue logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/199:12 am
DTW
- MYR
1 stop24h 38m
Multiple Airlines
Mon 8/173:31 pm
MYR
- DTW
1 stop21h 36m
Multiple Airlines
Deal found 5/31![Multiple Airlines logo]()
$281
This Super.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/217:30 am
DTW
- CHS
1 stop8h 53m
JetBlue
Tue 7/285:19 pm
CHS
- DTW
1 stop5h 26m
JetBlue
Deal found 6/3![JetBlue logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/219:12 am
DTW
- CHS
1 stop9h 02m
Multiple Airlines
Tue 7/2811:15 am
CHS
- DTW
1 stop25h 40m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- SAV
1 stop28h 43m
Multiple Airlines
Wed 7/2912:19 pm
SAV
- DTW
1 stop24h 36m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- SAV
1 stop8h 43m
Multiple Airlines
Sun 7/2610:05 am
SAV
- DTW
1 stop26h 50m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- SAV
1 stop28h 43m
Multiple Airlines
Thu 7/3010:05 am
SAV
- DTW
1 stop26h 50m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- GSP
1 stop22h 45m
Multiple Airlines
Sun 7/268:37 am
GSP
- DTW
1 stop28h 18m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- SAV
1 stop8h 43m
Multiple Airlines
Mon 7/276:00 am
SAV
- DTW
2 stops30h 55m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:12 am
DTW
- CHS
1 stop27h 52m
Multiple Airlines
Tue 7/2811:15 am
CHS
- DTW
1 stop25h 40m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:12 am
DTW
- CHS
1 stop9h 02m
Multiple Airlines
Tue 8/411:15 am
CHS
- DTW
1 stop25h 40m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:12 am
DTW
- CHS
1 stop9h 02m
Multiple Airlines
Wed 8/54:04 pm
CHS
- DTW
2 stops19h 28m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$267
One-way flights from Detroit to South CarolinaSearch for one-way flight options from Detroit to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 4, 2026.
Search for one-way flight options from Detroit to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:42 pm
DTW
- CLT
1 stop21h 49m
Frontier
Deal found 6/4![Frontier logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:42 pm
DTW
- CLT
1 stop8h 53m
Frontier
Deal found 6/3![Frontier logo]()
$85
This Trip.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/309:12 am
DTW
- CLT
1 stop11h 55m
Frontier
Deal found 6/2![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3012:42 pm
DTW
- CLT
1 stop8h 53m
Frontier
Deal found 6/3![Frontier logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:12 am
DTW
- CLT
1 stop11h 55m
Frontier
Deal found 6/1![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/189:12 am
DTW
- CLT
1 stop11h 55m
Frontier
Deal found 6/1![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:00 am
DTW
- SAV
1 stop26h 55m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$105
This Trip.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1612:42 pm
DTW
- CLT
1 stop8h 53m
Frontier
Deal found 6/2![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:00 am
DTW
- SAV
1 stop6h 55m
Multiple Airlines
Deal found 5/30![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:00 am
DTW
- GSP
1 stop20h 57m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$111
This Super.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:50 pm
DTW
- CLT
1 stop5h 13m
Frontier
Deal found 6/3![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3011:00 am
DTW
- GSP
1 stop29h 44m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$114
Find flight deals from Detroit to South Carolina
Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated June 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $204 (Kiwi.com) |
One-way from | $77 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $276 |
Good round-trip deal | $339 or less |
Good one-way deal | $218 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 4, 2026.
Use the filters below to find and compare flights from Detroit to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitMyrtle Beach
DTW - MYR
DTWMYR
Detroit Metropolitan Wayne County
Wed 8/19
8:41 am-10:38 am
Nonstop1h 57m
Myrtle Beach Intl
Wed 8/26
11:33 am-1:30 pm
Nonstop1h 57m
$299
DetroitColumbia
DTW - CAE
DTWCAE
Detroit Metropolitan Wayne County
Wed 6/24
10:13 am-2:16 pm
1 stop4h 03m
Columbia Metropolitan
Sat 7/4
10:31 am-2:34 pm
1 stop4h 03m
$309
DetroitSavannah
DTW - SAV
DTWSAV
Detroit Metropolitan Wayne County
Tue 8/18
5:20 am-9:16 am
1 stop3h 56m
Savannah/Hilton Head
Tue 8/25
6:11 pm-8:28 pm
Nonstop2h 17m
$309
DetroitHilton Head Island
DTW - HHH
DTWHHH
Detroit Metropolitan Wayne County
Wed 8/19
8:25 am-3:32 pm
1 stop7h 07m
Hilton Head Island
Wed 8/26
4:15 pm-11:21 pm
1 stop7h 06m
$323
DetroitSavannah
DTW - SAV
DTWSAV
Detroit Metropolitan Wayne County
Tue 9/1
6:00 am-4:25 pm
2 stops10h 25m
Savannah/Hilton Head
Tue 9/8
1:10 pm-9:50 pm
2 stops8h 40m
$329
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Tue 6/30
10:37 am-12:26 pm
Nonstop1h 49m
Charlotte Douglas
Tue 7/7
7:00 am-2:51 pm
1 stop7h 51m
$333
DetroitAugusta
DTW - AGS
DTWAGS
Detroit Metropolitan Wayne County
Wed 8/12
6:00 am-12:18 pm
1 stop6h 18m
Augusta Bush Field
Sat 8/15
5:40 pm-11:37 pm
1 stop5h 57m
$339
Quickest round-trip
DetroitMyrtle Beach
DTW - MYR
DTWMYR
Detroit Metropolitan Wayne County
Fri 9/18
10:00 am-11:54 am
Nonstop1h 54m
Myrtle Beach Intl
Fri 9/25
12:50 pm-2:47 pm
Nonstop1h 57m
$339
DetroitSavannah
DTW - SAV
DTWSAV
Detroit Metropolitan Wayne County
Tue 7/21
8:45 am-10:52 am
Nonstop2h 07m
Savannah/Hilton Head
Mon 7/27
6:10 pm-8:27 pm
Nonstop2h 17m
$339
DetroitAugusta
DTW - AGS
DTWAGS
Detroit Metropolitan Wayne County
Wed 8/12
4:25 pm-9:30 pm
1 stop5h 05m
Augusta Bush Field
Tue 8/18
7:15 pm-12:59 am
1 stop5h 44m
$339
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Detroit to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
DTW-MYR
DTW-CAE
DTW-SAV
DTW-AGS
DTW-HHH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to South Carolina
DTT-USSC
DTW-MYR
DTW-CAE
DTW-SAV
DTW-AGS
What is the cheapest month to book a flight from Detroit to South Carolina?
Currently, August is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $45). Flying from Detroit to South Carolina in May is currently the most expensive (average of $216). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to SC?
Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 4, 2026.
When flying from Detroit to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 12% versus a flight in the morning.
How much does it cost to fly round-trip from Detroit to South Carolina?
How far ahead should I book a flight from Detroit to South Carolina?
The best time to book flights from Detroit to South Carolina is 19 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest day to fly from Detroit to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Detroit to South Carolina. Price data was last updated on May 30, 2026.
Travelers seeking maximum savings on their Detroit to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 4, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAmerican Airlines from Detroit to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Detroit to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to South Carolina by cabin class
Find flights from Detroit to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and South Carolina flights
Browse other Detroit and South Carolina flight options. Last updated on June 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Detroit to South Carolina flights
Consider these flights traveling from Detroit to South Carolina.
Top 3 airlines flying from Detroit to South Carolina
Discover the top 3 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$172 | Average$408 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$218 | Average$398 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$233 | Average$372 | FlexibilityNo cancel fee | On-time63% |