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South Carolina

$50+ Cheap flights from Detroit (DTT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — CHS
Dec 23 — Dec 301
Tue 12/23
Tue 12/30
1 adult, Economy
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Find flight deals from Detroit to South Carolina

Cheapest flights from Detroit to South Carolina
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 23, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:00 amDTW - CHS
1 stop5h 00mSpirit Airlines
Fri 12/129:49 pmCHS - DTW
1 stop12h 19mSpirit Airlines
Deal found 11/22$116
This Expedia deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/167:08 amDTW - CLT
1 stop5h 54mMultiple Airlines
Tue 12/233:07 pmCLT - DTW
1 stop18h 05mMultiple Airlines
Deal found 11/21$144
This Cheapflightsfares deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/167:08 amDTW - CLT
1 stop5h 54mSpirit Airlines
Tue 12/239:38 pmCLT - DTW
1 stop11h 55mSpirit Airlines
Deal found 11/21$149
This Priceline deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:15 pmDTW - CLT
Nonstop1h 53mFrontier
Thu 1/19:24 amCLT - DTW
Nonstop1h 56mFrontier
Deal found 11/22$150
This Frontier deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:25 amDTW - CLT
1 stop10h 36mFrontier
Tue 12/309:24 amCLT - DTW
Nonstop1h 56mFrontier
Deal found 11/23$151
This Kiwi.com deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/76:00 amDTW - CHS
1 stop5h 00mSpirit Airlines
Thu 12/119:49 pmCHS - DTW
1 stop12h 19mSpirit Airlines
Deal found 11/21$151
This Frontier deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1812:15 pmDTW - CLT
Nonstop1h 53mFrontier
Sun 12/219:33 pmCLT - DTW
1 stop11h 20mFrontier
Deal found 11/22$152
This Kiwi.com deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:00 amDTW - SAV
1 stop6h 23mSpirit Airlines
Fri 12/121:18 pmSAV - DTW
1 stop18h 26mSpirit Airlines
Deal found 11/22$153
This Kiwi.com deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amDTW - CHS
1 stop5h 00mMultiple Airlines
Sat 12/137:00 amCHS - DTW
1 stop9h 54mMultiple Airlines
Deal found 11/21$153
This Mytrip deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:00 amDTW - CHS
1 stop5h 00mSpirit Airlines
Sat 12/1311:55 amCHS - DTW
2 stops20h 12mSpirit Airlines
Deal found 11/21$154
This Super.com deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:15 pmDTW - CLT
Nonstop1h 53mFrontier
Sun 12/283:07 pmCLT - DTW
1 stop17h 35mFrontier
Deal found 11/22$157
This Cheapflightsfares deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/167:08 amDTW - CLT
1 stop5h 54mSpirit Airlines
Fri 12/199:38 pmCLT - DTW
1 stop11h 55mSpirit Airlines
Deal found 11/20$158

Cheap flight deals from Detroit to South Carolina

Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated November 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$116
(Cheapflightsfares)

One-way from

$50
(Cheapflightsfares)

Popular in

November

Cheapest in

August

Average price

$367

Good round-trip deal

$299 or less

Good one-way deal

$110 or less
Provider with most accurate pricing for Detroit (DTT)-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Myrtle Beach Intl flights.
Search Deals
From Detroit (DTT) to South Carolina
Search Deals
One-way flight from Detroit (DTT) to South Carolina
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Detroit (DTT) to South Carolina.
Search Deals
Price to beat on a one-way flight from Detroit (DTT) to South Carolina.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 23, 2025.
Use the filters below to find and compare flights from Detroit to South Carolina that are best for you.

Fly from

Detroit

Fly to

South Carolina

Route

Depart

Return

Price

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Wed 1/21

7:15 am-1:38 pm

1 stop6h 23m

Charlotte Douglas

Wed 1/28

9:30 am-11:26 am

Nonstop1h 56m

$149

DetroitSavannah

DTW - SAV

DTWSAV

Detroit Metropolitan Wayne County

Mon 12/8

6:00 am-12:23 pm

1 stop6h 23m

Savannah/Hilton Head

Fri 12/12

1:18 pm-7:44 am

1 stop18h 26m

$153

DetroitCharleston

DTW - CHS

DTWCHS

Detroit Metropolitan Wayne County

Thu 1/8

8:22 am-4:10 pm

1 stop7h 48m

Charleston

Fri 1/9

5:05 pm-7:56 am

1 stop14h 51m

$158

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Thu 1/8

7:45 pm-9:32 pm

Nonstop1h 47m

Charlotte Douglas

Sun 1/11

6:00 am-7:55 am

Nonstop1h 55m

$169

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Thu 1/29

2:15 pm-4:05 pm

Nonstop1h 50m

Charlotte Douglas

Sun 2/1

12:59 pm-2:47 pm

Nonstop1h 48m

$169

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Sun 1/11

2:15 pm-4:05 pm

Nonstop1h 50m

Charlotte Douglas

Sat 1/17

6:00 am-7:55 am

Nonstop1h 55m

$169

DetroitSavannah

DTW - SAV

DTWSAV

Detroit Metropolitan Wayne County

Thu 1/8

10:08 pm-12:02 pm

1 stop13h 54m

Savannah/Hilton Head

Sun 1/18

12:58 pm-7:56 am

1 stop18h 58m

$176

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Wed 2/18

5:05 am-2:17 pm

1 stop9h 12m

Charlotte Douglas

Sun 2/22

3:12 pm-9:54 pm

1 stop6h 42m

$178

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Fri 1/16

10:37 am-4:02 pm

1 stop5h 25m

Charlotte Douglas

Mon 1/19

9:30 am-11:26 am

Nonstop1h 56m

$179

DetroitSavannah

DTW - SAV

DTWSAV

Detroit Metropolitan Wayne County

Sat 1/17

10:08 pm-12:02 pm

1 stop13h 54m

Savannah/Hilton Head

Mon 1/19

12:58 pm-12:19 am

1 stop11h 21m

$185

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/20

Showing 1-10 of 60 results
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Best time to book a flight from Detroit to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to South Carolina

What is the cheapest month to book a flight from Detroit to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $91). Flying from Detroit to South Carolina in December is currently the most expensive (average of $175). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to SC?

Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 23, 2025.

When flying from Detroit to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 18% versus a flight at noon.

What is the cheapest day to fly from Detroit to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Detroit to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Detroit to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Detroit to South Carolina

Explore weekly flight availability from Detroit to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 23, 2025.

The most flights from DTT to USSC are scheduled on a Wednesday (7 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from Detroit to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 23, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Detroit to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,252 reviews

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,252 reviews
Southwest
8.0
Very good
4,252 reviews

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,997 reviews
Southwest
8.0
Very good
4,252 reviews

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,046 reviews
Southwest
8.0
Very good
4,252 reviews

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,159 reviews
Southwest
8.0
Very good
4,252 reviews

Overall

8.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to South Carolina?

    Most people fly from Detroit All airports (DTT) if they book a flight from Detroit to South Carolina. Detroit All airports is conveniently located just 0.6 mi from Detroit’s city center.

  • How long is the flight from Detroit to South Carolina?

    There are many flights that can get you from Detroit to South Carolina in 4h 23m. Fly via Spirit Airlines, Delta, or American Airlines to get the fastest option. There are 584 mi between Detroit and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Detroit to South Carolina one-way?

    $70 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Spirit Airlines and JetBlue, with prices starting from $73 and $81, respectively.

  • What are the most popular routes from Detroit to South Carolina?

    The most popular route from Detroit to South Carolina is Detroit Metropolitan Wayne County - Charlotte Douglas. You may also consider Detroit Metropolitan Wayne County - Charleston or Detroit Metropolitan Wayne County - Savannah/Hilton Head.

  • What are the most reliable airlines from Detroit to South Carolina?

    The top 3 most reliable airlines when flying from Detroit to South Carolina are Air France (96%), WestJet (89%) and Endeavor Airlines (86%).

  • What are the cheapest flights from Detroit to South Carolina?

    Looking for the cheapest flight from Detroit to South Carolina? While on average our users pay $329, our data indicates the cheapest price to be $119. The most popular route (Detroit Metropolitan Wayne County - Charlotte Douglas), is priced around $127.

  • Can I find deals for flights from Detroit to South Carolina that include hotel bookings?

    Yes. In addition to deals on Detroit to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to South Carolina.

  • Can I find deals for business class flights from Detroit to South Carolina?

    Yes. Cheapflights offers flight deals from Detroit to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $91). Flying from Detroit to South Carolina in December is currently the most expensive (average of $175). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Detroit to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Detroit to South Carolina

Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$76Average$172FlexibilityNo cancel feeOn-time65%
DeltaCheapest$159Average$382FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$197Average$346FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$231Average$377FlexibilityNo cancel feeOn-time63%

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