$66+ Cheap flights from Detroit (DTT) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — CHS
Apr 7 — Apr 141
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to South Carolina with Cheapflights
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Cheapest flights from Detroit to South CarolinaExplore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 8, 2026.
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:58 pm
DTW
- CLT
1 stop8h 03m
Spirit Airlines
Tue 5/197:12 am
CLT
- DTW
1 stop5h 40m
Spirit Airlines
Deal found 3/4![Spirit Airlines logo]()
$141
This Cheapflightsfares deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:22 am
DTW
- CLT
1 stop7h 38m
Spirit Airlines
Sat 4/1810:16 am
CLT
- DTW
1 stop8h 57m
Spirit Airlines
Deal found 3/4![Spirit Airlines logo]()
$145
This Cheapflightsfares deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:22 am
DTW
- CLT
1 stop7h 38m
Spirit Airlines
Wed 4/89:18 am
CLT
- DTW
1 stop6h 32m
Spirit Airlines
Deal found 3/8![Spirit Airlines logo]()
$146
This Priceline deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:22 am
DTW
- CLT
1 stop7h 38m
Spirit Airlines
Tue 4/287:12 am
CLT
- DTW
1 stop5h 40m
Spirit Airlines
Deal found 3/7![Spirit Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/411:34 am
DTW
- CLT
1 stop7h 26m
Multiple Airlines
Tue 4/79:17 pm
CLT
- DTW
1 stop11h 29m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$150
This Mytrip deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:22 am
DTW
- CLT
1 stop7h 38m
Spirit Airlines
Wed 4/89:17 pm
CLT
- DTW
1 stop11h 29m
Spirit Airlines
Deal found 3/8![Spirit Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/173:59 pm
DTW
- CLT
1 stop16h 22m
Multiple Airlines
Wed 3/189:00 pm
CLT
- DTW
1 stop12h 23m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$152
This CheapOair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/411:34 am
DTW
- CLT
1 stop12h 19m
Spirit Airlines
Mon 4/139:17 pm
CLT
- DTW
1 stop11h 29m
Spirit Airlines
Deal found 3/5![Spirit Airlines logo]()
$154
This Trip.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:22 am
DTW
- CLT
1 stop7h 38m
Multiple Airlines
Thu 4/1611:48 am
CLT
- DTW
Nonstop1h 59m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$155
This Cheapflightsfares deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:58 pm
DTW
- CLT
1 stop8h 03m
Spirit Airlines
Fri 5/810:16 am
CLT
- DTW
1 stop8h 37m
Spirit Airlines
Deal found 3/6![Spirit Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:53 pm
DTW
- CLT
1 stop26h 00m
Spirit Airlines
Tue 4/79:17 pm
CLT
- DTW
1 stop11h 29m
Spirit Airlines
Deal found 3/7![Spirit Airlines logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/42:06 pm
DTW
- MYR
1 stop18h 46m
Spirit Airlines
Tue 4/149:49 pm
MYR
- DTW
1 stop10h 13m
Spirit Airlines
Deal found 3/4![Spirit Airlines logo]()
$199
Best flights from Detroit to South CarolinaDiscover carefully curated flight deals from Detroit to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 8, 2026.
Discover carefully curated flight deals from Detroit to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 8, 2026.
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:17 pm
DTW
- CLT
Nonstop1h 49m
Delta
Tue 4/1412:40 pm
CLT
- DTW
Nonstop1h 53m
Delta
Deal found 3/8![Delta logo]()
$283
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2011:55 am
DTW
- CAE
1 stop4h 56m
American Airlines
Sat 5/235:13 pm
CAE
- DTW
1 stop6h 26m
American Airlines
Deal found 3/3![American Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
DTW
- CAE
1 stop7h 41m
United Airlines
Sat 5/167:38 pm
CAE
- DTW
1 stop4h 17m
United Airlines
Deal found 3/3![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:55 am
DTW
- MYR
2 stops9h 15m
Southwest
Tue 6/22:10 pm
MYR
- DTW
2 stops7h 25m
Southwest
Deal found 3/8![Southwest logo]()
$344
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:16 pm
DTW
- CLT
Nonstop1h 44m
Delta
Tue 4/2112:40 pm
CLT
- DTW
Nonstop1h 53m
Delta
Deal found 3/6![Delta logo]()
$283
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
DTW
- HHH
1 stop7h 40m
American Airlines
Wed 5/132:58 pm
HHH
- DTW
1 stop4h 11m
American Airlines
Deal found 3/8![American Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:50 am
DTW
- HHH
1 stop5h 31m
United Airlines
Fri 6/53:05 pm
HHH
- DTW
1 stop7h 09m
United Airlines
Deal found 3/7![United Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:30 am
DTW
- CLT
1 stop7h 00m
Delta
Sat 7/1812:59 pm
CLT
- DTW
Nonstop1h 46m
Delta
Deal found 3/7![Delta logo]()
$293
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:00 pm
DTW
- CLT
2 stops9h 40m
Southwest
Sun 5/248:35 am
CLT
- DTW
1 stop4h 05m
Southwest
Deal found 3/6![Southwest logo]()
$348
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:19 am
DTW
- CLT
Nonstop1h 50m
Delta
Sat 5/95:35 am
CLT
- DTW
1 stop3h 51m
Delta
Deal found 3/8![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/182:40 pm
DTW
- CAE
1 stop4h 21m
United Airlines
Sat 3/215:15 pm
CAE
- DTW
1 stop6h 19m
United Airlines
Deal found 3/6![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:20 pm
DTW
- GSP
1 stop6h 40m
Southwest
Thu 4/166:25 pm
GSP
- DTW
1 stop3h 55m
Southwest
Deal found 3/8![Southwest logo]()
$349
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
DTW
- AGS
2 stops6h 27m
American Airlines
Sat 4/253:03 pm
AGS
- DTW
1 stop4h 06m
American Airlines
Deal found 3/3![American Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:15 pm
DTW
- CLT
1 stop5h 58m
Delta
Tue 5/265:00 pm
CLT
- DTW
Nonstop1h 48m
Delta
Deal found 3/5![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 am
DTW
- CAE
2 stops7h 50m
United Airlines
Sun 4/193:25 pm
CAE
- DTW
1 stop6h 47m
United Airlines
Deal found 3/8![United Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:00 am
DTW
- GSP
2 stops10h 45m
Southwest
Thu 4/1612:35 pm
GSP
- DTW
2 stops10h 55m
Southwest
Deal found 3/8![Southwest logo]()
$366
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:09 am
DTW
- CLT
Nonstop1h 46m
Delta
Wed 5/205:00 pm
CLT
- DTW
Nonstop1h 48m
Delta
Deal found 3/4![Delta logo]()
$303
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:11 am
DTW
- FLO
1 stop5h 39m
American Airlines
Tue 5/196:15 am
FLO
- DTW
1 stop4h 17m
American Airlines
Deal found 3/4![American Airlines logo]()
$373
This Delta deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/11:45 pm
DTW
- CLT
1 stop4h 29m
Delta
Sat 7/44:30 pm
CLT
- DTW
1 stop6h 14m
Delta
Deal found 3/4![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:55 am
DTW
- MYR
2 stops9h 15m
Southwest
Fri 6/52:05 pm
MYR
- DTW
2 stops6h 55m
Southwest
Deal found 3/8![Southwest logo]()
$369
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/139:43 am
DTW
- FLO
2 stops12h 04m
American Airlines
Wed 5/205:20 am
FLO
- DTW
2 stops9h 00m
American Airlines
Deal found 3/4![American Airlines logo]()
$383
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:29 am
DTW
- CLT
1 stop5h 58m
Delta
Wed 5/135:30 pm
CLT
- DTW
1 stop5h 14m
Delta
Deal found 3/8![Delta logo]()
$303
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:00 am
DTW
- MYR
1 stop5h 17m
United Airlines
Sat 4/183:15 pm
MYR
- DTW
1 stop7h 02m
United Airlines
Deal found 3/3![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/164:00 pm
DTW
- GSP
1 stop6h 15m
Southwest
Thu 4/236:25 am
GSP
- DTW
1 stop5h 55m
Southwest
Deal found 3/6![Southwest logo]()
$386
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:57 am
DTW
- FLO
1 stop3h 53m
American Airlines
Wed 5/205:20 am
FLO
- DTW
1 stop4h 07m
American Airlines
Deal found 3/4![American Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:18 pm
DTW
- SAV
1 stop7h 41m
United Airlines
Mon 5/47:04 pm
SAV
- DTW
1 stop4h 55m
United Airlines
Deal found 3/4![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:40 am
DTW
- MYR
Nonstop1h 57m
Delta
Tue 6/211:32 am
MYR
- DTW
Nonstop1h 58m
Delta
Deal found 3/8![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
DTW
- GSP
1 stop6h 00m
Southwest
Mon 5/186:25 pm
GSP
- DTW
1 stop3h 55m
Southwest
Deal found 3/3![Southwest logo]()
$386
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2111:36 am
DTW
- FLO
1 stop6h 14m
American Airlines
Sun 3/225:16 am
FLO
- DTW
1 stop4h 09m
American Airlines
Deal found 3/7![American Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:47 pm
DTW
- SAV
1 stop4h 12m
United Airlines
Sun 4/265:40 am
SAV
- DTW
1 stop4h 34m
United Airlines
Deal found 3/3![United Airlines logo]()
$409
Last-minute flights from Detroit to South CarolinaDiscover last-minute flight deals from Detroit to South Carolina. Data last updated March 8, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to South Carolina. Data last updated March 8, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/173:59 pm
DTW
- CLT
1 stop16h 22m
Multiple Airlines
Wed 3/189:00 pm
CLT
- DTW
1 stop12h 23m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$152
This Mytrip deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:05 am
DTW
- CLT
2 stops14h 12m
Spirit Airlines
Tue 3/319:17 pm
CLT
- DTW
1 stop11h 29m
Spirit Airlines
Deal found 3/7![Spirit Airlines logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:53 pm
DTW
- CLT
1 stop26h 00m
Spirit Airlines
Tue 4/79:17 pm
CLT
- DTW
1 stop11h 29m
Spirit Airlines
Deal found 3/7![Spirit Airlines logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/411:34 am
DTW
- CLT
1 stop7h 26m
Multiple Airlines
Tue 4/79:17 pm
CLT
- DTW
1 stop11h 29m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$150
This CheapOair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/411:34 am
DTW
- CLT
1 stop12h 19m
Spirit Airlines
Mon 4/139:17 pm
CLT
- DTW
1 stop11h 29m
Spirit Airlines
Deal found 3/5![Spirit Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/42:06 pm
DTW
- MYR
1 stop18h 46m
Spirit Airlines
Tue 4/149:49 pm
MYR
- DTW
1 stop10h 13m
Spirit Airlines
Deal found 3/4![Spirit Airlines logo]()
$199
This Cheapflightsfares deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:22 am
DTW
- CLT
1 stop7h 38m
Spirit Airlines
Wed 4/89:18 am
CLT
- DTW
1 stop6h 32m
Spirit Airlines
Deal found 3/8![Spirit Airlines logo]()
$146
This Trip.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:22 am
DTW
- CLT
1 stop7h 38m
Multiple Airlines
Thu 4/1611:48 am
CLT
- DTW
Nonstop1h 59m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$155
This Mytrip deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:22 am
DTW
- CLT
1 stop7h 38m
Spirit Airlines
Wed 4/89:17 pm
CLT
- DTW
1 stop11h 29m
Spirit Airlines
Deal found 3/8![Spirit Airlines logo]()
$151
This Cheapflightsfares deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:22 am
DTW
- CLT
1 stop7h 38m
Spirit Airlines
Sat 4/1810:16 am
CLT
- DTW
1 stop8h 57m
Spirit Airlines
Deal found 3/4![Spirit Airlines logo]()
$145
This Priceline deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:22 am
DTW
- CLT
1 stop7h 38m
Spirit Airlines
Tue 4/287:12 am
CLT
- DTW
1 stop5h 40m
Spirit Airlines
Deal found 3/7![Spirit Airlines logo]()
$149
This Cheapflightsfares deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:22 am
DTW
- CLT
1 stop7h 38m
Spirit Airlines
Tue 4/217:12 am
CLT
- DTW
1 stop5h 40m
Spirit Airlines
Deal found 3/6![Spirit Airlines logo]()
$157
One-way flights from Detroit to South CarolinaSearch for one-way flight options from Detroit to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 8, 2026.
Search for one-way flight options from Detroit to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 8, 2026.
This Super.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:58 pm
DTW
- CLT
1 stop8h 03m
Spirit Airlines
Deal found 3/4![Spirit Airlines logo]()
$66
This Cheapflightsfares deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:16 am
DTW
- MYR
1 stop5h 28m
Spirit Airlines
Deal found 3/5![Spirit Airlines logo]()
$67
This Spirit deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:34 am
DTW
- SAV
1 stop4h 21m
Spirit Airlines
Deal found 3/8![Spirit Airlines logo]()
$68
This Cheapflightsfares deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:22 am
DTW
- CLT
1 stop7h 38m
Spirit Airlines
Deal found 3/8![Spirit Airlines logo]()
$68
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/29:16 am
DTW
- MYR
1 stop5h 28m
Spirit Airlines
Deal found 3/4![Spirit Airlines logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:58 pm
DTW
- CLT
1 stop8h 03m
Spirit Airlines
Deal found 3/4![Spirit Airlines logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:22 am
DTW
- CLT
1 stop7h 38m
Spirit Airlines
Deal found 3/7![Spirit Airlines logo]()
$73
This Mytrip deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/411:34 am
DTW
- CLT
1 stop12h 19m
Spirit Airlines
Deal found 3/8![Spirit Airlines logo]()
$77
This Mytrip deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/309:53 pm
DTW
- CHS
1 stop13h 16m
Spirit Airlines
Deal found 3/4![Spirit Airlines logo]()
$77
This Trip.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:53 pm
DTW
- CHS
1 stop13h 16m
Spirit Airlines
Deal found 3/6![Spirit Airlines logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/39:16 am
DTW
- MYR
1 stop5h 28m
Spirit Airlines
Deal found 3/3![Spirit Airlines logo]()
$79
This Super.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:09 pm
DTW
- CLT
1 stop4h 28m
Frontier
Deal found 3/7![Frontier logo]()
$79
Find flight deals from Detroit to South Carolina
Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated March 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $141 (Kiwi.com) |
One-way from | $66 (Super.com) |
Popular in | January |
Cheapest in | August |
Average price | $424 |
Good round-trip deal | $349 or less |
Good one-way deal | $209 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2026.
Use the filters below to find and compare flights from Detroit to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Tue 4/7
2:17 pm-4:06 pm
Nonstop1h 49m
Charlotte Douglas
Tue 4/14
12:40 pm-2:33 pm
Nonstop1h 53m
$283
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Tue 4/14
2:16 pm-4:00 pm
Nonstop1h 44m
Charlotte Douglas
Tue 4/21
12:40 pm-2:33 pm
Nonstop1h 53m
$283
DetroitColumbia
DTW - CAE
DTWCAE
Detroit Metropolitan Wayne County
Wed 5/20
11:55 am-4:51 pm
1 stop4h 56m
Columbia Metropolitan
Sat 5/23
5:13 pm-11:39 pm
1 stop6h 26m
$289
DetroitColumbia
DTW - CAE
DTWCAE
Detroit Metropolitan Wayne County
Wed 5/13
6:00 am-1:41 pm
1 stop7h 41m
Columbia Metropolitan
Sat 5/16
7:38 pm-11:55 pm
1 stop4h 17m
$289
DetroitHilton Head Island
DTW - HHH
DTWHHH
Detroit Metropolitan Wayne County
Sat 5/9
6:00 am-1:40 pm
1 stop7h 40m
Hilton Head Island
Wed 5/13
2:58 pm-7:09 pm
1 stop4h 11m
$289
DetroitHilton Head Island
DTW - HHH
DTWHHH
Detroit Metropolitan Wayne County
Tue 5/26
8:50 am-2:21 pm
1 stop5h 31m
Hilton Head Island
Fri 6/5
3:05 pm-10:14 pm
1 stop7h 09m
$289
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Wed 7/15
6:30 am-1:30 pm
1 stop7h 00m
Charlotte Douglas
Sat 7/18
12:59 pm-2:45 pm
Nonstop1h 46m
$293
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Wed 5/6
7:19 am-9:09 am
Nonstop1h 50m
Charlotte Douglas
Sat 5/9
5:35 am-9:26 am
1 stop3h 51m
$293
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Sat 5/23
12:15 pm-6:13 pm
1 stop5h 58m
Charlotte Douglas
Tue 5/26
5:00 pm-6:48 pm
Nonstop1h 48m
$293
Quickest round-trip
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Fri 5/15
7:09 am-8:55 am
Nonstop1h 46m
Charlotte Douglas
Wed 5/20
5:00 pm-6:48 pm
Nonstop1h 48m
$303
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Detroit to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
DTW-SAV
DTW-CHS
DTW-CAE
DTW-CLT
DTW-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to South Carolina
DTT-USSC
DTW-SAV
DTW-CHS
DTW-CAE
DTW-CLT
What is the cheapest month to book a flight from Detroit to South Carolina?
Currently, May is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $86). Flying from Detroit to South Carolina in January is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to SC?
Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 8, 2026.
When flying from Detroit to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 27% versus a flight at noon.
What is the cheapest day to fly from Detroit to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Detroit to South Carolina. Price data was last updated on February 21, 2026.
Travelers seeking maximum savings on their Detroit to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Detroit to South Carolina
Explore weekly flight availability from Detroit to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 8, 2026.
The most flights from DTT to USSC are scheduled on a Monday (6 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 8, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Detroit to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Detroit to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to South Carolina by cabin class
Find flights from Detroit to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and South Carolina flights
Browse other Detroit and South Carolina flight options. Last updated on March 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Detroit to South Carolina flights
Consider these flights traveling from Detroit to South Carolina.
Top 4 airlines flying from Detroit to South Carolina
Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$64 | Average$161 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$158 | Average$393 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$198 | Average$341 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$207 | Average$370 | FlexibilityNo cancel fee | On-time63% |