South Carolina

$66+ Cheap flights from Detroit (DTT) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — CHS
Apr 7 — Apr 141
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Cheap flight deals from Detroit to South Carolina

Cheapest flights from Detroit to South Carolina
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 8, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:58 pm
DTW
-
CLT
1 stop8h 03m
Spirit Airlines
Tue 5/197:12 am
CLT
-
DTW
1 stop5h 40m
Spirit Airlines
Deal found 3/4$141
This Cheapflightsfares deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:22 am
DTW
-
CLT
1 stop7h 38m
Spirit Airlines
Sat 4/1810:16 am
CLT
-
DTW
1 stop8h 57m
Spirit Airlines
Deal found 3/4$145
This Cheapflightsfares deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:22 am
DTW
-
CLT
1 stop7h 38m
Spirit Airlines
Wed 4/89:18 am
CLT
-
DTW
1 stop6h 32m
Spirit Airlines
Deal found 3/8$146
This Priceline deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:22 am
DTW
-
CLT
1 stop7h 38m
Spirit Airlines
Tue 4/287:12 am
CLT
-
DTW
1 stop5h 40m
Spirit Airlines
Deal found 3/7$149
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/411:34 am
DTW
-
CLT
1 stop7h 26m
Multiple Airlines
Tue 4/79:17 pm
CLT
-
DTW
1 stop11h 29m
Multiple Airlines
Deal found 3/6$150
This Mytrip deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:22 am
DTW
-
CLT
1 stop7h 38m
Spirit Airlines
Wed 4/89:17 pm
CLT
-
DTW
1 stop11h 29m
Spirit Airlines
Deal found 3/8$151
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/173:59 pm
DTW
-
CLT
1 stop16h 22m
Multiple Airlines
Wed 3/189:00 pm
CLT
-
DTW
1 stop12h 23m
Multiple Airlines
Deal found 3/4$152
This CheapOair deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/411:34 am
DTW
-
CLT
1 stop12h 19m
Spirit Airlines
Mon 4/139:17 pm
CLT
-
DTW
1 stop11h 29m
Spirit Airlines
Deal found 3/5$154
This Trip.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:22 am
DTW
-
CLT
1 stop7h 38m
Multiple Airlines
Thu 4/1611:48 am
CLT
-
DTW
Nonstop1h 59m
Multiple Airlines
Deal found 3/5$155
This Cheapflightsfares deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:58 pm
DTW
-
CLT
1 stop8h 03m
Spirit Airlines
Fri 5/810:16 am
CLT
-
DTW
1 stop8h 37m
Spirit Airlines
Deal found 3/6$157
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:53 pm
DTW
-
CLT
1 stop26h 00m
Spirit Airlines
Tue 4/79:17 pm
CLT
-
DTW
1 stop11h 29m
Spirit Airlines
Deal found 3/7$158
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/42:06 pm
DTW
-
MYR
1 stop18h 46m
Spirit Airlines
Tue 4/149:49 pm
MYR
-
DTW
1 stop10h 13m
Spirit Airlines
Deal found 3/4$199

Find flight deals from Detroit to South Carolina

Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated March 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$141
(Kiwi.com)

One-way from

$66
(Super.com)

Popular in

January

Cheapest in

August

Average price

$424

Good round-trip deal

$349 or less

Good one-way deal

$209 or less
Provider with most accurate pricing for Detroit (DTT)-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Detroit (DTT)-Myrtle Beach Intl flights.
From Detroit (DTT) to South Carolina
One-way flight from Detroit (DTT) to South Carolina
Highest demand for flights based on searches. 27% potential increase in price ($115 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($18 potential savings vs. average RT price).
Average for round-trip flights in March 2026
Price to beat on a round-trip flight from Detroit (DTT) to South Carolina.
Price to beat on a one-way flight from Detroit (DTT) to South Carolina.

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2026.
Use the filters below to find and compare flights from Detroit to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Tue 4/7

2:17 pm-4:06 pm

Nonstop1h 49m

Charlotte Douglas

Tue 4/14

12:40 pm-2:33 pm

Nonstop1h 53m

$283

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Tue 4/14

2:16 pm-4:00 pm

Nonstop1h 44m

Charlotte Douglas

Tue 4/21

12:40 pm-2:33 pm

Nonstop1h 53m

$283

DetroitColumbia

DTW - CAE

DTWCAE

Detroit Metropolitan Wayne County

Wed 5/20

11:55 am-4:51 pm

1 stop4h 56m

Columbia Metropolitan

Sat 5/23

5:13 pm-11:39 pm

1 stop6h 26m

$289

DetroitColumbia

DTW - CAE

DTWCAE

Detroit Metropolitan Wayne County

Wed 5/13

6:00 am-1:41 pm

1 stop7h 41m

Columbia Metropolitan

Sat 5/16

7:38 pm-11:55 pm

1 stop4h 17m

$289

DetroitHilton Head Island

DTW - HHH

DTWHHH

Detroit Metropolitan Wayne County

Sat 5/9

6:00 am-1:40 pm

1 stop7h 40m

Hilton Head Island

Wed 5/13

2:58 pm-7:09 pm

1 stop4h 11m

$289

DetroitHilton Head Island

DTW - HHH

DTWHHH

Detroit Metropolitan Wayne County

Tue 5/26

8:50 am-2:21 pm

1 stop5h 31m

Hilton Head Island

Fri 6/5

3:05 pm-10:14 pm

1 stop7h 09m

$289

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Wed 7/15

6:30 am-1:30 pm

1 stop7h 00m

Charlotte Douglas

Sat 7/18

12:59 pm-2:45 pm

Nonstop1h 46m

$293

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Wed 5/6

7:19 am-9:09 am

Nonstop1h 50m

Charlotte Douglas

Sat 5/9

5:35 am-9:26 am

1 stop3h 51m

$293

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Sat 5/23

12:15 pm-6:13 pm

1 stop5h 58m

Charlotte Douglas

Tue 5/26

5:00 pm-6:48 pm

Nonstop1h 48m

$293
Quickest round-trip

DetroitCharlotte

DTW - CLT

DTWCLT

Detroit Metropolitan Wayne County

Fri 5/15

7:09 am-8:55 am

Nonstop1h 46m

Charlotte Douglas

Wed 5/20

5:00 pm-6:48 pm

Nonstop1h 48m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/8

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
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6

Best time to book a flight from Detroit to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to South Carolina

What is the cheapest month to book a flight from Detroit to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $86). Flying from Detroit to South Carolina in January is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to SC?

Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 8, 2026.

When flying from Detroit to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 27% versus a flight at noon.

What is the cheapest day to fly from Detroit to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Detroit to South Carolina. Price data was last updated on February 21, 2026.

Travelers seeking maximum savings on their Detroit to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Detroit to South Carolina

Explore weekly flight availability from Detroit to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 8, 2026.

The most flights from DTT to USSC are scheduled on a Monday (6 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 8, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Detroit to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Food

7.0

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Related info for your journey

Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Detroit to South Carolina?

    Most people fly from Detroit All airports (DTT) if they book a flight from Detroit to South Carolina. Detroit All airports is conveniently located just 0.6 mi from Detroit’s city center.

  • How long is the flight from Detroit to South Carolina?

    There are many flights that can get you from Detroit to South Carolina in 1h 49m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. There are 500 mi between Detroit and South Carolina. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Detroit to South Carolina one-way?

    $92 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on American Airlines and Frontier, with prices starting from $130 and $132, respectively.

  • What are the most popular routes from Detroit to South Carolina?

  • What are the most reliable airlines from Detroit to South Carolina?

    The top 3 most reliable airlines when flying from Detroit to South Carolina are Republic Airways (80%), Endeavor Airlines (78%) and WestJet (77%).

  • What are the cheapest flights from Detroit to South Carolina?

    Looking for the cheapest flight from Detroit to South Carolina? While on average our users pay $509, our data indicates the cheapest price to be $268. The most popular route (Detroit Metropolitan Wayne County - Myrtle Beach Intl), is priced around $152.

  • Can I find deals for flights from Detroit to South Carolina that include hotel bookings?

    Yes. In addition to deals on Detroit to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to South Carolina.

  • Can I find deals for business class flights from Detroit to South Carolina?

    Yes. Cheapflights offers flight deals from Detroit to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $86). Flying from Detroit to South Carolina in January is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Detroit to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Detroit to South Carolina

Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$64Average$161FlexibilityNo cancel feeOn-time65%
DeltaCheapest$158Average$393FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$198Average$341FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$207Average$370FlexibilityNo cancel feeOn-time63%

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