$49+ Cheap flights from Detroit (DTT) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/16. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — CHS
Mar 24 — Mar 311
1 adult, Economy
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Find cheap flights from Detroit to South Carolina with Cheapflights
1. Tell us where you want to go
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Cheapest flights from Detroit to South CarolinaExplore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.
This Priceline deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:55 am
DTW
- CLT
Nonstop1h 51m
Frontier
Sat 5/164:16 pm
CLT
- DTW
1 stop8h 22m
Frontier
Deal found 2/20![Frontier logo]()
$139
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:51 pm
DTW
- CLT
Nonstop1h 51m
Frontier
Mon 5/411:33 am
CLT
- DTW
1 stop25h 14m
Frontier
Deal found 2/19![Frontier logo]()
$140
This Cheapflightsfares deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/252:06 pm
DTW
- CLT
1 stop5h 55m
Spirit Airlines
Thu 3/269:18 am
CLT
- DTW
1 stop6h 32m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/299:16 am
DTW
- CLT
1 stop9h 58m
Multiple Airlines
Mon 5/45:30 pm
CLT
- DTW
1 stop14h 22m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$142
This Frontier deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:51 pm
DTW
- CLT
Nonstop1h 51m
Frontier
Sun 4/127:30 am
CLT
- DTW
Nonstop1h 59m
Frontier
Deal found 2/22![Frontier logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:59 pm
DTW
- CHS
1 stop11h 33m
Spirit Airlines
Tue 5/53:26 pm
CHS
- DTW
1 stop8h 54m
Spirit Airlines
Deal found 2/21![Spirit Airlines logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/252:06 pm
DTW
- CLT
1 stop5h 55m
Spirit Airlines
Tue 4/79:18 am
CLT
- DTW
1 stop6h 32m
Spirit Airlines
Deal found 2/21![Spirit Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:57 pm
DTW
- CLT
1 stop5h 13m
Multiple Airlines
Mon 5/185:30 pm
CLT
- DTW
1 stop14h 22m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/149:53 pm
DTW
- CHS
1 stop10h 39m
Spirit Airlines
Sat 4/183:26 pm
CHS
- DTW
1 stop8h 54m
Spirit Airlines
Deal found 2/20![Spirit Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/128:59 pm
DTW
- CLT
1 stop15h 00m
Spirit Airlines
Tue 5/193:09 pm
CLT
- DTW
1 stop9h 11m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$147
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:48 pm
DTW
- CLT
1 stop11h 10m
Frontier
Mon 3/910:42 am
CLT
- DTW
Nonstop1h 58m
Frontier
Deal found 2/18![Frontier logo]()
$148
This Expedia deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:01 pm
DTW
- CLT
Nonstop1h 51m
Multiple Airlines
Mon 3/239:00 pm
CLT
- DTW
1 stop12h 23m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$149
Best flights from Detroit to South CarolinaDiscover carefully curated flight deals from Detroit to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 22, 2026.
Discover carefully curated flight deals from Detroit to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 22, 2026.
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:00 pm
DTW
- CLT
Nonstop1h 50m
Delta
Tue 5/195:00 pm
CLT
- DTW
Nonstop1h 48m
Delta
Deal found 2/18![Delta logo]()
$159
This Spirit deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/182:06 pm
DTW
- CLT
1 stop5h 55m
Spirit Airlines
Sun 3/229:00 pm
CLT
- DTW
1 stop12h 23m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/164:08 pm
DTW
- CAE
1 stop25h 44m
Multiple Airlines
Mon 4/206:42 pm
CAE
- DTW
1 stop14h 56m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$212
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:47 pm
DTW
- CAE
1 stop4h 12m
United Airlines
Wed 4/223:25 pm
CAE
- DTW
1 stop6h 47m
United Airlines
Deal found 2/18![United Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
DTW
- HHH
1 stop4h 32m
American Airlines
Tue 5/123:44 pm
HHH
- DTW
1 stop6h 32m
American Airlines
Deal found 2/19![American Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:25 am
DTW
- MYR
2 stops7h 25m
Southwest
Mon 8/178:10 am
MYR
- DTW
1 stop7h 00m
Southwest
Deal found 2/18![Southwest logo]()
$324
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:00 pm
DTW
- CLT
Nonstop1h 50m
Delta
Wed 5/205:35 am
CLT
- DTW
1 stop3h 47m
Delta
Deal found 2/18![Delta logo]()
$169
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:10 am
DTW
- CLT
Nonstop1h 46m
Delta
Sat 5/165:00 pm
CLT
- DTW
Nonstop1h 48m
Delta
Deal found 2/18![Delta logo]()
$199
This CheapOair deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/55:45 am
DTW
- CHS
1 stop11h 55m
Spirit Airlines
Mon 3/95:00 pm
CHS
- DTW
1 stop7h 09m
Spirit Airlines
Deal found 2/18![Spirit Airlines logo]()
$228
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:00 pm
DTW
- CLT
Nonstop1h 50m
Delta
Tue 5/195:00 pm
CLT
- DTW
Nonstop1h 48m
Delta
Deal found 2/18![Delta logo]()
$199
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:00 pm
DTW
- CLT
Nonstop1h 50m
Delta
Tue 5/196:00 am
CLT
- DTW
Nonstop1h 46m
Delta
Deal found 2/18![Delta logo]()
$199
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:00 am
DTW
- HHH
1 stop4h 32m
American Airlines
Mon 4/276:39 pm
HHH
- DTW
1 stop5h 46m
American Airlines
Deal found 2/19![American Airlines logo]()
$269
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:18 am
DTW
- HHH
1 stop6h 58m
United Airlines
Thu 4/234:11 pm
HHH
- DTW
2 stops7h 48m
United Airlines
Deal found 2/19![United Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/910:26 am
DTW
- CLT
Nonstop1h 49m
Delta
Wed 5/205:35 am
CLT
- DTW
1 stop5h 34m
Delta
Deal found 2/18![Delta logo]()
$209
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:48 am
DTW
- CAE
1 stop4h 13m
United Airlines
Tue 3/107:39 pm
CAE
- DTW
1 stop4h 18m
United Airlines
Deal found 2/19![United Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:11 am
DTW
- HHH
1 stop4h 15m
American Airlines
Sat 5/92:54 pm
HHH
- DTW
2 stops8h 31m
American Airlines
Deal found 2/18![American Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:00 am
DTW
- GSP
1 stop11h 53m
Multiple Airlines
Mon 4/205:43 pm
GSP
- DTW
2 stops17h 55m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$313
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:00 am
DTW
- GSP
1 stop6h 00m
Southwest
Wed 3/256:20 am
GSP
- DTW
1 stop5h 55m
Southwest
Deal found 2/18![Southwest logo]()
$343
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2511:19 am
DTW
- HHH
1 stop4h 21m
American Airlines
Fri 5/16:39 pm
HHH
- DTW
1 stop3h 49m
American Airlines
Deal found 2/18![American Airlines logo]()
$306
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/107:50 pm
DTW
- CLT
Nonstop1h 43m
Delta
Tue 4/1412:40 pm
CLT
- DTW
Nonstop1h 53m
Delta
Deal found 2/19![Delta logo]()
$231
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:05 pm
DTW
- SAV
1 stop5h 10m
United Airlines
Wed 4/228:00 am
SAV
- DTW
1 stop5h 20m
United Airlines
Deal found 2/21![United Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
DTW
- GSP
1 stop5h 45m
Southwest
Wed 3/256:20 am
GSP
- DTW
1 stop5h 55m
Southwest
Deal found 2/18![Southwest logo]()
$355
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:00 pm
DTW
- CLT
Nonstop1h 47m
Delta
Thu 5/216:00 am
CLT
- DTW
Nonstop1h 46m
Delta
Deal found 2/18![Delta logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:05 am
DTW
- GSP
1 stop7h 07m
Multiple Airlines
Mon 3/26:49 pm
GSP
- DTW
2 stops40h 18m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$378
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:19 am
DTW
- HHH
1 stop6h 22m
United Airlines
Sat 5/93:08 pm
HHH
- DTW
1 stop7h 00m
United Airlines
Deal found 2/18![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:49 pm
DTW
- FLO
1 stop4h 03m
American Airlines
Sun 4/195:20 am
FLO
- DTW
1 stop4h 07m
American Airlines
Deal found 2/20![American Airlines logo]()
$323
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/252:15 pm
DTW
- GSP
2 stops8h 25m
Southwest
Tue 3/316:20 am
GSP
- DTW
1 stop5h 55m
Southwest
Deal found 2/19![Southwest logo]()
$360
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/47:45 pm
DTW
- AGS
1 stop4h 11m
American Airlines
Wed 4/85:00 pm
AGS
- DTW
1 stop5h 11m
American Airlines
Deal found 2/19![American Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:40 am
DTW
- GSP
2 stops9h 10m
Southwest
Thu 4/168:10 am
GSP
- DTW
2 stops6h 45m
Southwest
Deal found 2/19![Southwest logo]()
$377
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:00 am
DTW
- CAE
1 stop7h 17m
United Airlines
Mon 3/97:39 pm
CAE
- DTW
1 stop4h 18m
United Airlines
Deal found 2/18![United Airlines logo]()
$349
Last-minute flights from Detroit to South CarolinaDiscover last-minute flight deals from Detroit to South Carolina. Data last updated February 22, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to South Carolina. Data last updated February 22, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:17 pm
DTW
- CLT
Nonstop1h 51m
Frontier
Fri 3/1311:07 am
CLT
- DTW
Nonstop1h 58m
Frontier
Deal found 2/18![Frontier logo]()
$139
This Priceline deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:17 pm
DTW
- CLT
Nonstop1h 51m
Multiple Airlines
Fri 3/139:18 am
CLT
- DTW
1 stop6h 32m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$140
This Cheapflightsfares deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/102:06 pm
DTW
- CLT
1 stop6h 06m
Spirit Airlines
Thu 3/129:18 am
CLT
- DTW
1 stop6h 32m
Spirit Airlines
Deal found 2/20![Spirit Airlines logo]()
$154
This Priceline deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:01 pm
DTW
- CLT
Nonstop1h 51m
Multiple Airlines
Mon 3/231:20 pm
CLT
- DTW
1 stop9h 12m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:00 am
DTW
- CLT
1 stop7h 52m
Spirit Airlines
Wed 4/153:09 pm
CLT
- DTW
1 stop9h 11m
Spirit Airlines
Deal found 2/21![Spirit Airlines logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:22 am
DTW
- CLT
1 stop9h 26m
Multiple Airlines
Wed 4/153:09 pm
CLT
- DTW
1 stop9h 11m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:06 pm
DTW
- CLT
1 stop5h 55m
Spirit Airlines
Thu 4/1611:15 am
CLT
- DTW
1 stop4h 58m
Spirit Airlines
Deal found 2/21![Spirit Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:22 am
DTW
- CLT
1 stop9h 26m
Multiple Airlines
Wed 4/89:17 pm
CLT
- DTW
1 stop11h 29m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:06 pm
DTW
- CLT
1 stop5h 55m
Spirit Airlines
Mon 4/139:17 pm
CLT
- DTW
1 stop11h 29m
Spirit Airlines
Deal found 2/21![Spirit Airlines logo]()
$152
This Cheapflightsfares deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/252:06 pm
DTW
- CLT
1 stop5h 55m
Spirit Airlines
Thu 3/269:18 am
CLT
- DTW
1 stop6h 32m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/252:06 pm
DTW
- CLT
1 stop5h 55m
Spirit Airlines
Tue 4/79:18 am
CLT
- DTW
1 stop6h 32m
Spirit Airlines
Deal found 2/21![Spirit Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/252:06 pm
DTW
- CLT
1 stop5h 55m
Multiple Airlines
Wed 4/155:30 pm
CLT
- DTW
1 stop22h 43m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$147
One-way flights from Detroit to South CarolinaSearch for one-way flight options from Detroit to South Carolina. Find affordable one-way fares based on user searches. Data last updated February 22, 2026.
Search for one-way flight options from Detroit to South Carolina. Find affordable one-way fares based on user searches. Data last updated February 22, 2026.
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:01 pm
DTW
- CLT
Nonstop1h 51m
Frontier
Deal found 2/19![Frontier logo]()
$49
This Super.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:55 am
DTW
- CLT
Nonstop1h 51m
Frontier
Deal found 2/19![Frontier logo]()
$58
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:55 am
DTW
- CLT
Nonstop1h 51m
Frontier
Deal found 2/19![Frontier logo]()
$59
This Super.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/211:28 pm
DTW
- CLT
1 stop7h 05m
Spirit Airlines
Deal found 2/22![Spirit Airlines logo]()
$67
This CheapOair deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:34 am
DTW
- SAV
1 stop4h 21m
Spirit Airlines
Deal found 2/18![Spirit Airlines logo]()
$68
This Super.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:06 pm
DTW
- CLT
1 stop5h 55m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$68
This Cheapflightsfares deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:34 am
DTW
- SAV
1 stop4h 21m
Spirit Airlines
Deal found 2/20![Spirit Airlines logo]()
$69
This Expedia deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/182:06 pm
DTW
- CLT
1 stop5h 55m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:00 am
DTW
- CLT
1 stop12h 48m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$72
This Super.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:41 am
DTW
- CLT
Nonstop1h 51m
Frontier
Deal found 2/20![Frontier logo]()
$73
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/161:28 pm
DTW
- CLT
1 stop7h 05m
Spirit Airlines
Deal found 2/18![Spirit Airlines logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/12:06 pm
DTW
- CLT
1 stop4h 54m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$76
Find flight deals from Detroit to South Carolina
Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated February 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $139 (Priceline) |
One-way from | $49 (Frontier) |
Popular in | January |
Cheapest in | August |
Average price | $319 |
Good round-trip deal | $369 or less |
Good one-way deal | $264 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
Use the filters below to find and compare flights from Detroit to South Carolina that are best for you.
Fly from
Detroit
Fly to
South Carolina
Route
Depart
Return
Price
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Wed 5/13
2:00 pm-3:50 pm
Nonstop1h 50m
Charlotte Douglas
Tue 5/19
5:00 pm-6:48 pm
Nonstop1h 48m
$159
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Wed 3/18
2:06 pm-8:01 pm
1 stop5h 55m
Charlotte Douglas
Sun 3/22
9:00 pm-9:23 am
1 stop12h 23m
$168
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Wed 5/13
2:00 pm-3:50 pm
Nonstop1h 50m
Charlotte Douglas
Wed 5/20
5:35 am-9:22 am
1 stop3h 47m
$169
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Wed 5/13
7:10 am-8:56 am
Nonstop1h 46m
Charlotte Douglas
Sat 5/16
5:00 pm-6:48 pm
Nonstop1h 48m
$199
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Sat 5/9
2:00 pm-3:50 pm
Nonstop1h 50m
Charlotte Douglas
Tue 5/19
5:00 pm-6:48 pm
Nonstop1h 48m
$199
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Sat 5/16
2:00 pm-3:50 pm
Nonstop1h 50m
Charlotte Douglas
Tue 5/19
6:00 am-7:46 am
Nonstop1h 46m
$199
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Sat 5/9
10:26 am-12:15 pm
Nonstop1h 49m
Charlotte Douglas
Wed 5/20
5:35 am-11:09 am
1 stop5h 34m
$209
DetroitColumbia
DTW - CAE
DTWCAE
Detroit Metropolitan Wayne County
Thu 4/16
4:08 pm-5:52 pm
1 stop25h 44m
Columbia Metropolitan
Mon 4/20
6:42 pm-9:38 am
1 stop14h 56m
$212
DetroitCharleston
DTW - CHS
DTWCHS
Detroit Metropolitan Wayne County
Thu 3/5
5:45 am-5:40 pm
1 stop11h 55m
Charleston
Mon 3/9
5:00 pm-12:09 am
1 stop7h 09m
$228
DetroitCharlotte
DTW - CLT
DTWCLT
Detroit Metropolitan Wayne County
Fri 4/10
7:50 pm-9:33 pm
Nonstop1h 43m
Charlotte Douglas
Tue 4/14
12:40 pm-2:33 pm
Nonstop1h 53m
$231
Showing 1-10 of 60 results
Best time to book a flight from Detroit to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
DTW-CLT
DTW-CHS
DTW-GSP
DTW-AGS
DTW-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to South Carolina
DTT-USSC
DTW-CLT
DTW-CHS
DTW-GSP
DTW-AGS
What is the cheapest month to book a flight from Detroit to South Carolina?
Currently, May is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $89). Flying from Detroit to South Carolina in January is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to SC?
Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 22, 2026.
When flying from Detroit to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 27% versus a flight at noon.
What is the cheapest day to fly from Detroit to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Detroit to South Carolina. Price data was last updated on February 17, 2026.
Travelers seeking maximum savings on their Detroit to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Detroit to South Carolina
Explore weekly flight availability from Detroit to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 22, 2026.
The most flights from DTT to USSC are scheduled on a Monday (7 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (3 on average).
How much does it cost to fly round-trip from Detroit to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 22, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Detroit to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Detroit to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to South Carolina by cabin class
Find flights from Detroit to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and South Carolina flights
Browse other Detroit and South Carolina flight options. Last updated on February 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Detroit to South Carolina flights
Consider these flights traveling from Detroit to South Carolina.
Top 4 airlines flying from Detroit to South Carolina
Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$64 | Average$160 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$158 | Average$394 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$198 | Average$340 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$207 | Average$362 | FlexibilityNo cancel fee | On-time63% |