$83+ Cheap flights from Detroit (DTT) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — CHS
Nov 1 — Nov 81
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Detroit to South CarolinaExplore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2026.
Explore the most affordable flight options available from Detroit to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:30 am -
1 stop8h 14m
Mon 11/28:52 pm -
2 stops26h 45m
Deal found 9/30![Multiple Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:53 pm -
2 stops38h 45m
Wed 11/117:54 pm -
1 stop27h 43m
Deal found 9/30![Multiple Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:35 pm -
1 stop17h 03m
Tue 11/33:00 pm -
1 stop20h 40m
Deal found 10/1![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:51 pm -
2 stops13h 47m
Thu 10/2910:13 pm -
1 stop25h 24m
Deal found 9/30![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:53 pm -
2 stops25h 06m
Wed 11/48:24 pm -
1 stop21h 29m
Deal found 9/30![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:41 pm -
1 stop18h 48m
Mon 11/168:52 pm -
2 stops26h 45m
Deal found 9/27![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:53 pm -
2 stops38h 45m
Tue 11/103:00 pm -
1 stop20h 40m
Deal found 9/30![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:07 pm -
1 stop11h 41m
Tue 11/33:00 pm -
1 stop20h 40m
Deal found 10/1![Multiple Airlines logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:53 pm -
2 stops13h 45m
Wed 11/117:54 pm -
1 stop27h 43m
Deal found 9/30![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:35 pm -
1 stop17h 03m
Wed 11/46:00 am -
2 stops18h 44m
Deal found 10/1![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:07 pm -
1 stop11h 41m
Thu 11/52:13 pm -
1 stop18h 39m
Deal found 10/1![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2612:41 pm -
2 stops19h 57m
Wed 11/117:54 pm -
1 stop27h 43m
Deal found 9/30![Multiple Airlines logo]()
$238
Best flights from Detroit to South CarolinaDiscover carefully curated flight deals from Detroit to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 2, 2026.
Discover carefully curated flight deals from Detroit to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 2, 2026.
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:55 am -
2 stops9h 35m
Sat 11/78:20 am -
2 stops9h 10m
Deal found 9/27![Southwest logo]()
$289
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:50 pm -
Nonstop2h 12m
Mon 12/146:47 pm -
Nonstop2h 13m
Deal found 10/1![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:26 am -
2 stops6h 51m
Sat 11/75:37 pm -
1 stop6h 20m
Deal found 9/28![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/265:08 am -
1 stop5h 30m
Wed 12/307:05 pm -
1 stop5h 31m
Deal found 9/29![American Airlines logo]()
$436
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:50 pm -
1 stop3h 57m
Thu 11/55:40 am -
1 stop3h 47m
Deal found 9/29![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/145:15 am -
1 stop4h 45m
Sat 2/2010:15 am -
2 stops9h 55m
Deal found 9/28![Southwest logo]()
$371
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/65:20 am -
1 stop4h 48m
Fri 3/1211:10 am -
Nonstop1h 59m
Deal found 9/30![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:26 am -
2 stops11h 42m
Sun 11/17:54 pm -
1 stop4h 05m
Deal found 9/29![United Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:50 am -
2 stops9h 35m
Sun 12/68:20 am -
2 stops8h 55m
Deal found 9/29![Southwest logo]()
$376
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:25 am -
Nonstop1h 55m
Sat 11/710:52 am -
1 stop5h 02m
Deal found 9/28![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:10 am -
1 stop5h 49m
Sat 10/101:50 pm -
1 stop7h 44m
Deal found 9/29![American Airlines logo]()
$439
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:40 am -
2 stops9h 00m
Wed 12/236:40 am -
2 stops10h 00m
Deal found 10/2![Southwest logo]()
$388
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:25 am -
1 stop7h 05m
Tue 11/312:23 pm -
1 stop6h 18m
Deal found 9/27![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:00 am -
1 stop5h 35m
Sat 10/242:51 pm -
1 stop7h 24m
Deal found 9/30![United Airlines logo]()
$455
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:05 am -
2 stops7h 25m
Fri 10/301:05 pm -
2 stops8h 40m
Deal found 10/1![Southwest logo]()
$401
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:25 am -
1 stop6h 05m
Wed 11/412:23 pm -
2 stops9h 49m
Deal found 9/29![Delta logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:00 am -
2 stops9h 53m
Tue 12/1512:33 pm -
2 stops10h 37m
Deal found 9/28![American Airlines logo]()
$499
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:00 am -
2 stops7h 26m
Thu 10/155:38 pm -
1 stop6h 21m
Deal found 10/1![United Airlines logo]()
$462
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:25 pm -
2 stops6h 40m
Wed 11/48:05 am -
2 stops13h 20m
Deal found 9/30![Southwest logo]()
$407
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:25 am -
1 stop4h 49m
Thu 10/155:59 pm -
1 stop6h 59m
Deal found 10/1![Delta logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:23 am -
1 stop4h 40m
Tue 12/812:33 pm -
2 stops8h 58m
Deal found 9/27![American Airlines logo]()
$534
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:49 am -
2 stops8h 19m
Tue 12/15:45 pm -
1 stop4h 29m
Deal found 9/27![United Airlines logo]()
$486
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:40 am -
2 stops7h 40m
Thu 1/710:55 am -
2 stops8h 55m
Deal found 9/27![Southwest logo]()
$410
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/207:48 pm -
1 stop4h 11m
Mon 11/236:53 pm -
Nonstop2h 07m
Deal found 9/30![Delta logo]()
$399
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:00 am -
1 stop4h 05m
Sat 10/2411:36 am -
1 stop4h 43m
Deal found 10/1![American Airlines logo]()
$542
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:50 am -
2 stops11h 05m
Sun 11/228:15 am -
2 stops9h 00m
Deal found 9/27![Southwest logo]()
$435
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:26 am -
2 stops11h 42m
Sun 11/87:54 pm -
1 stop4h 05m
Deal found 9/29![United Airlines logo]()
$534
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am -
2 stops11h 38m
Sun 11/15:54 pm -
1 stop4h 47m
Deal found 9/30![American Airlines logo]()
$578
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:10 am -
2 stops13h 20m
Tue 10/271:35 pm -
2 stops8h 10m
Deal found 9/28![Southwest logo]()
$438
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:49 pm -
Nonstop2h 16m
Tue 10/277:10 am -
Nonstop2h 08m
Deal found 10/1![Delta logo]()
$439
Last-minute flights from Detroit to South CarolinaDiscover last-minute flight deals from Detroit to South Carolina. Data last updated October 2, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to South Carolina. Data last updated October 2, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:51 pm -
2 stops13h 47m
Thu 10/2910:13 pm -
1 stop25h 24m
Deal found 9/30![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2612:41 pm -
2 stops19h 57m
Wed 11/117:54 pm -
1 stop27h 43m
Deal found 9/30![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:53 pm -
2 stops25h 06m
Wed 11/48:24 pm -
1 stop21h 29m
Deal found 9/30![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:53 pm -
2 stops13h 45m
Wed 11/117:54 pm -
1 stop27h 43m
Deal found 9/30![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:53 pm -
2 stops38h 45m
Wed 11/117:54 pm -
1 stop27h 43m
Deal found 9/30![Multiple Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:53 pm -
2 stops38h 45m
Tue 11/103:00 pm -
1 stop20h 40m
Deal found 9/30![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:30 am -
1 stop8h 14m
Mon 11/28:52 pm -
2 stops26h 45m
Deal found 9/30![Multiple Airlines logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:35 pm -
1 stop17h 03m
Tue 11/33:00 pm -
1 stop20h 40m
Deal found 10/1![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:35 pm -
1 stop17h 03m
Wed 11/46:00 am -
2 stops18h 44m
Deal found 10/1![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:07 pm -
1 stop11h 41m
Tue 11/33:00 pm -
1 stop20h 40m
Deal found 10/1![Multiple Airlines logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Sun 11/19:07 pm -
1 stop11h 41m
Thu 11/52:13 pm -
1 stop18h 39m
Deal found 10/1![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:41 pm -
1 stop18h 48m
Mon 11/168:52 pm -
2 stops26h 45m
Deal found 9/27![Multiple Airlines logo]()
$229
One-way flights from Detroit to South CarolinaSearch for one-way flight options from Detroit to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 2, 2026.
Search for one-way flight options from Detroit to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:30 am -
1 stop23h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:02 pm -
2 stops18h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Frontier logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:53 pm -
2 stops13h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:30 am -
2 stops7h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:53 pm -
2 stops38h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Frontier logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/24:08 pm -
2 stops16h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:59 pm -
1 stop11h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:53 pm -
2 stops38h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:53 pm -
2 stops25h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:07 pm -
1 stop11h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/1![Multiple Airlines logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:33 pm -
1 stop21h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:37 pm -
2 stops37h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![Frontier logo]()
$125
Find flight deals from Detroit to South Carolina
Keep the following information in mind while searching for Detroit to South Carolina flight deals. Data was last updated October 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $194 (Kiwi.com) |
One-way from | $83 (Kiwi.com) |
Popular in | August |
Cheapest in | February |
Average price | $454 |
Good round-trip deal | $439 or less |
Good one-way deal | $233 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 2, 2026.
Use the filters below to find and compare flights from Detroit to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Tue 11/10
7:46 am-3:14 pm
1 stop7h 28m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
DetroitMyrtle Beach
DTW Detroit Metropolitan Wayne County - MYR Myrtle Beach Intl
DTWMYR
Detroit Metropolitan Wayne County
Wed 2/10
5:15 am-1:05 pm
2 stops7h 50m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$182
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Thu 10/22
4:55 pm-9:35 pm
1 stop4h 40m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$189
DetroitGreenville
DTW Detroit Metropolitan Wayne County - GSP Greenville
DTWGSP
Detroit Metropolitan Wayne County
Sat 10/31
11:25 am-3:25 pm
1 stop4h 00m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$189
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Tue 10/27
11:05 am-7:35 pm
2 stops8h 30m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$194
DetroitMyrtle Beach
DTW Detroit Metropolitan Wayne County - MYR Myrtle Beach Intl
DTWMYR
Detroit Metropolitan Wayne County
Tue 3/30
8:30 am-10:29 am
Nonstop1h 59m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$199
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Mon 1/4
3:50 pm-6:03 pm
Nonstop2h 13m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$199
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Tue 12/22
8:55 am-11:20 am
Nonstop2h 25m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$199
DetroitMyrtle Beach
DTW Detroit Metropolitan Wayne County - MYR Myrtle Beach Intl
DTWMYR
Detroit Metropolitan Wayne County
Wed 12/30
5:40 am-2:20 pm
1 stop8h 40m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$208
DetroitCharleston
DTW Detroit Metropolitan Wayne County - CHS Charleston
DTWCHS
Detroit Metropolitan Wayne County
Tue 3/30
7:05 am-2:48 pm
1 stop7h 43m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$209
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Detroit to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Detroit with our price prediction graph.
DTW-GSP
DTW-MYR
DTW-CHS
DTW-CAE
DTW-HHH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit to South Carolina
DTT-USSC
DTW-GSP
DTW-MYR
DTW-CHS
DTW-CAE
What is the cheapest month to book a flight from Detroit to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Detroit to South Carolina (average of $346). Flying from Detroit to South Carolina in March is currently the most expensive (average of $463). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTT to SC?
Find hourly flight availability from Detroit to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 2, 2026.
When flying from Detroit to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 20% versus a flight in the morning.
How much does it cost to fly round-trip from Detroit to South Carolina?
Airfare is below average for this route at the moment.
Detroit to South Carolina flights typically cost between $439 and $623 in October.The cheapest round-trip price found within the last 5 days was $218 on Multiple Airlines (Oct 30-Nov 11).
How far ahead should I book a flight from Detroit to South Carolina?
The best time to book flights from Detroit to South Carolina is 61 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest day to fly from Detroit to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Detroit to South Carolina. Price data was last updated on September 26, 2026.
Travelers seeking maximum savings on their Detroit to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 2, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAmerican Airlines from Detroit to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Related info for your journey
Find useful and relevant information for your journey from Detroit to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Detroit to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to South Carolina by cabin class
Find flights from Detroit to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and South Carolina flights
Browse other Detroit and South Carolina flight options. Last updated on October 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Detroit to South Carolina flights
Consider these flights traveling from Detroit to South Carolina.
Top 4 airlines flying from Detroit to South Carolina
Discover the top 4 airlines that operate flights from Detroit to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$235 | Average$403 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$414 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$283 | Average$371 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$299 | Average$444 | FlexibilityNo cancel fee | On-timeN/A |