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South Carolina

$319+ Cheap flights from Columbia, MO (COU) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
COU — CHS
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Columbia to South Carolina

Keep the following information in mind while searching for Columbia to South Carolina flight deals. Data was last updated September 15, 2025.

Round-trip from

$319
(American Airlines)
From Columbia Regional to South Carolina
Search Deals

Find flight deals from Columbia to South Carolina

Cheapest flights from Columbia to South Carolina
Explore the most affordable flight options available from Columbia to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:01 amCOU - HHH
2 stops9h 50mAmerican Airlines
Sat 11/111:16 amHHH - COU
2 stops9h 03mAmerican Airlines
Deal found 9/13$319
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:24 amCOU - HHH
2 stops9h 23mAmerican Airlines
Sat 10/41:57 pmHHH - COU
1 stop7h 24mAmerican Airlines
Deal found 9/15$334
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:33 pmCOU - CLT
1 stop4h 55mAmerican Airlines
Sat 10/412:10 pmCLT - COU
1 stop6h 53mAmerican Airlines
Deal found 9/14$378
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/202:05 pmCOU - CLT
1 stop5h 32mAmerican Airlines
Sat 11/221:01 pmCLT - COU
1 stop6h 35mAmerican Airlines
Deal found 9/13$400
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/307:24 amCOU - CHS
1 stop5h 40mAmerican Airlines
Sat 10/47:06 amCHS - COU
1 stop5h 52mAmerican Airlines
Deal found 9/14$430
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/302:52 pmCOU - CLT
2 stops22h 18mUnited Airlines
Sat 10/46:00 amCLT - COU
2 stops16h 27mUnited Airlines
Deal found 9/14$557
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/208:00 amCOU - CLT
2 stops25h 02mUnited Airlines
Sat 11/227:44 pmCLT - COU
2 stops19h 42mUnited Airlines
Deal found 9/13$597
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/308:00 amCOU - CHS
1 stop11h 08mUnited Airlines
Sat 10/46:02 amCHS - COU
1 stop9h 15mUnited Airlines
Deal found 9/15$737
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/286:24 amCOU - MYR
2 stops6h 51mAmerican Airlines
Thu 10/27:00 amMYR - COU
1 stop6h 00mAmerican Airlines
Deal found 9/12$830
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:17 amCOU - MYR
2 stops7h 58mAmerican Airlines
Thu 12/255:13 pmMYR - COU
1 stop6h 19mAmerican Airlines
Deal found 9/13$885

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Columbia to South Carolina that are best for you.

Fly from

Columbia

Fly to

South Carolina

Route

Depart

Return

Price

ColumbiaHilton Head Island

COU - HHH

COUHHH

Columbia Regional

Tue 10/28

6:01 am-4:51 pm

2 stops9h 50m

Hilton Head Island

Sat 11/1

11:16 am-7:19 pm

2 stops9h 03m

$319

ColumbiaHilton Head Island

COU - HHH

COUHHH

Columbia Regional

Tue 9/30

6:24 am-4:47 pm

2 stops9h 23m

Hilton Head Island

Sat 10/4

1:57 pm-8:21 pm

1 stop7h 24m

$334

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Tue 9/30

6:33 pm-12:28 am

1 stop4h 55m

Charlotte Douglas

Sat 10/4

12:10 pm-6:03 pm

1 stop6h 53m

$378

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Thu 11/20

2:05 pm-8:37 pm

1 stop5h 32m

Charlotte Douglas

Sat 11/22

1:01 pm-6:36 pm

1 stop6h 35m

$400

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Tue 9/30

7:24 am-2:04 pm

1 stop5h 40m

Charleston

Sat 10/4

7:06 am-11:58 am

1 stop5h 52m

$430

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Tue 9/30

2:52 pm-2:10 pm

2 stops22h 18m

Charlotte Douglas

Sat 10/4

6:00 am-9:27 pm

2 stops16h 27m

$557

ColumbiaHilton Head Island

COU - HHH

COUHHH

Columbia Regional

Thu 1/15

6:57 am-5:34 pm

2 stops9h 37m

Hilton Head Island

Mon 1/19

6:14 pm-11:19 am

3 stops18h 05m

$564

ColumbiaCharlotte

COU - CLT

COUCLT

Columbia Regional

Thu 11/20

8:00 am-10:02 am

2 stops25h 02m

Charlotte Douglas

Sat 11/22

7:44 pm-2:26 pm

2 stops19h 42m

$597

ColumbiaCharleston

COU - CHS

COUCHS

Columbia Regional

Tue 9/30

8:00 am-8:08 pm

1 stop11h 08m

Charleston

Sat 10/4

6:02 am-2:17 pm

1 stop9h 15m

$737

ColumbiaMyrtle Beach

COU - MYR

COUMYR

Columbia Regional

Sun 9/28

6:24 am-2:15 pm

2 stops6h 51m

Myrtle Beach Intl

Thu 10/2

7:00 am-12:00 pm

1 stop6h 00m

$830

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 15 results
1
2

Best time to book a flight from Columbia to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 15, 2025.
See what other customers who have flown with American Airlines from Columbia to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Overall

7.2

Comfort

7.2

Boarding

7.5

Crew

8.0

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Overall

7.2

Comfort

7.2

Boarding

7.5

Crew

8.0

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Columbia to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to South Carolina?

    Columbia Regional (COU), located 11.1 mi from the city center, is the airport you fly out of when you book flights from Columbia to South Carolina.

  • How long is the flight from Columbia, Missouri to South Carolina?

    Departing from Columbia, Missouri to South Carolina will take you 9h 50m. There are 791 mi between Columbia, Missouri and South Carolina. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Columbia, Missouri to South Carolina?

    When deciding which route to take from Columbia, Missouri to South Carolina consider Columbia Regional - Myrtle Beach Intl, Columbia Regional - Charleston or Columbia Regional - Charlotte Douglas as they are the most popular.

  • Can I find deals for flights from Columbia to South Carolina that include hotel bookings?

    Yes. In addition to deals on Columbia to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to South Carolina.

  • Can I find deals for business class flights from Columbia to South Carolina?

    Yes. Cheapflights offers flight deals from Columbia to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Columbia, Missouri to South Carolina (average of $217). Flying from Columbia, Missouri to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Columbia to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Columbia to South Carolina

Discover the top airline that operate flights from Columbia to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$437Average$470FlexibilityNo cancel feeOn-time71%

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