South Carolina

$197+ Cheap flights from Cape Cod and the Islands to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/17. Fares are subject to change and may not be available on all flights or dates of travel.
MVY — CHS
Mar 5 — Mar 121
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Cheap flight deals from Cape Cod and the Islands to South Carolina

Cheapest flights from Cape Cod and the Islands to South Carolina
Explore the most affordable flight options available from Cape Cod and the Islands to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/84:59 pm
MVY
-
SAV
1 stop5h 32m
Delta
Tue 7/146:05 am
SAV
-
MVY
1 stop5h 15m
Delta
Deal found 2/1$206
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:25 am
MVY
-
SAV
1 stop7h 36m
JetBlue
Tue 8/2511:20 am
SAV
-
MVY
1 stop4h 41m
JetBlue
Deal found 2/2$243
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/224:59 pm
MVY
-
SAV
1 stop5h 32m
Delta
Wed 6/247:25 am
SAV
-
MVY
1 stop6h 54m
Delta
Deal found 2/2$318
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:52 am
ACK
-
CHS
1 stop4h 53m
JetBlue
Wed 6/311:40 am
CHS
-
ACK
1 stop4h 51m
JetBlue
Deal found 2/2$328
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:02 pm
MVY
-
CHS
1 stop5h 26m
Delta
Sun 5/316:00 am
CHS
-
MVY
1 stop6h 38m
Delta
Deal found 2/1$426
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1511:25 am
MVY
-
CHS
1 stop7h 40m
JetBlue
Wed 8/1911:00 am
CHS
-
MVY
1 stop5h 01m
JetBlue
Deal found 2/2$468
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:04 pm
MVY
-
CHS
1 stop6h 09m
Delta
Sun 5/316:00 am
CHS
-
MVY
1 stop6h 38m
Delta
Deal found 2/1$484
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/217:05 am
HYA
-
CHS
1 stop5h 13m
JetBlue
Wed 2/2510:20 am
CHS
-
HYA
1 stop7h 00m
JetBlue
Deal found 2/2$500
This JetBlue deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/111:26 am
MVY
-
SAV
1 stop6h 06m
JetBlue
Sat 8/1511:20 am
SAV
-
MVY
1 stop4h 41m
JetBlue
Deal found 2/2$502
This JetBlue deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:25 am
MVY
-
SAV
1 stop7h 36m
JetBlue
Sun 8/1611:20 am
SAV
-
MVY
1 stop4h 41m
JetBlue
Deal found 2/1$524
This JetBlue deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1712:07 pm
HYA
-
CHS
1 stop6h 35m
JetBlue
Fri 3/2010:50 am
CHS
-
HYA
1 stop6h 30m
JetBlue
Deal found 2/1$555
This JetBlue deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:16 am
HYA
-
CHS
1 stop7h 29m
JetBlue
Sun 9/138:00 am
CHS
-
HYA
1 stop7h 00m
JetBlue
Deal found 1/31$570

Find flight deals from Cape Cod and the Islands to South Carolina

Keep the following information in mind while searching for Cape Cod and the Islands to South Carolina flight deals. Data was last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$206
(Delta)

One-way from

$197
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$152
Provider with most accurate pricing for Boston Logan Intl-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Boston Logan Intl-Myrtle Beach Intl flights.
From Cape Cod and the Islands to South Carolina
One-way flight from Cape Cod and the Islands to South Carolina
Highest demand for flights based on searches. 15% potential increase in price ($40 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($12 potential savings vs. average RT price).
Average for round-trip flights in February 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cape Cod and the Islands to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Cape Cod and the Islands to South Carolina that are best for you.

Fly from

Cape Cod and the Islands

Fly to

South Carolina

Route

Depart

Return

Price

West TisburySavannah

MVY - SAV

MVYSAV

West Tisbury Martha's Vineyard

Wed 7/8

4:59 pm-10:31 pm

1 stop5h 32m

Savannah/Hilton Head

Tue 7/14

6:05 am-11:20 am

1 stop5h 15m

$206

West TisburySavannah

MVY - SAV

MVYSAV

West Tisbury Martha's Vineyard

Mon 6/22

4:59 pm-10:31 pm

1 stop5h 32m

Savannah/Hilton Head

Wed 6/24

7:25 am-2:19 pm

1 stop6h 54m

$318

NantucketCharleston

ACK - CHS

ACKCHS

Nantucket Memorial

Mon 6/1

10:52 am-3:45 pm

1 stop4h 53m

Charleston

Wed 6/3

11:40 am-4:31 pm

1 stop4h 51m

$328

West TisburyCharleston

MVY - CHS

MVYCHS

West Tisbury Martha's Vineyard

Fri 5/29

4:02 pm-9:28 pm

1 stop5h 26m

Charleston

Sun 5/31

6:00 am-12:38 pm

1 stop6h 38m

$426

West TisburyCharleston

MVY - CHS

MVYCHS

West Tisbury Martha's Vineyard

Thu 5/28

12:04 pm-6:13 pm

1 stop6h 09m

Charleston

Sun 5/31

6:00 am-12:38 pm

1 stop6h 38m

$484

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Sat 2/21

7:05 am-12:18 pm

1 stop5h 13m

Charleston

Wed 2/25

10:20 am-5:20 pm

1 stop7h 00m

$500

West TisburySavannah

MVY - SAV

MVYSAV

West Tisbury Martha's Vineyard

Sat 8/1

11:26 am-5:32 pm

1 stop6h 06m

Savannah/Hilton Head

Sat 8/15

11:20 am-4:01 pm

1 stop4h 41m

$502

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Tue 3/17

12:07 pm-6:42 pm

1 stop6h 35m

Charleston

Fri 3/20

10:50 am-5:20 pm

1 stop6h 30m

$555

NantucketCharlotte

ACK - CLT

ACKCLT

Nantucket Memorial

Fri 5/29

3:49 pm-9:51 pm

2 stops30h 02m

Charlotte Douglas

Tue 6/2

6:00 am-2:51 pm

2 stops8h 51m

$608

West TisburySavannah

MVY - SAV

MVYSAV

West Tisbury Martha's Vineyard

Sat 6/20

3:10 pm-9:30 pm

1 stop6h 20m

Savannah/Hilton Head

Sat 6/27

7:25 am-2:19 pm

1 stop6h 54m

$671

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 33 results
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Best time to book a flight from Cape Cod and the Islands to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Cape Cod and the Islands with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cape Cod and the Islands to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Cape Cod and the Islands to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Cape Cod and the Islands to South Carolina?

    Delta, JetBlue, and United Airlines can get you from Cape Cod and the Islands to South Carolina in just under 4h 53m. Your travel time can differ by up to 25h 09m. The distance between Cape Cod and the Islands and South Carolina is about 796 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Cape Cod and the Islands to South Carolina that include hotel bookings?

    Yes. In addition to deals on Cape Cod and the Islands to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cape Cod and the Islands to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Cod and the Islands to South Carolina.

  • Can I find deals for business class flights from Cape Cod and the Islands to South Carolina?

    Yes. Cheapflights offers flight deals from Cape Cod and the Islands to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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