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South Carolina

$103+ Cheap flights from Cape Cod and the Islands to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/29. Fares are subject to change and may not be available on all flights or dates of travel.
ACK — CHS
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Cape Cod and the Islands to South Carolina

Keep the following information in mind while searching for Cape Cod and the Islands to South Carolina flight deals. Data was last updated July 31, 2025.

Round-trip from

$206
(Delta)

One-way from

$103
(American Airlines)

Popular in

April

Cheapest in

February

Average price

$196
From Cape Cod and the Islands to South Carolina
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One-way flight from Cape Cod and the Islands to South Carolina
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Highest demand for flights based on searches. 13% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Cape Cod and the Islands to South Carolina

Cheapest flights from Cape Cod and the Islands to South Carolina
Explore the most affordable flight options available from Cape Cod and the Islands to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/202:13 pmMVY - CHS
1 stop7h 09mDelta
Tue 8/266:00 amCHS - MVY
1 stop5h 04mDelta
Deal found 7/31$206
This Trip.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1210:16 amHYA - CHS
1 stop7h 29mJetBlue
Mon 9/156:40 pmCHS - HYA
1 stop14h 51mJetBlue
Deal found 7/30$315
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/213:26 pmACK - CLT
1 stop25h 47mDelta
Sat 8/237:37 pmCLT - ACK
1 stop19h 09mDelta
Deal found 7/30$325
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/161:40 pmHYA - CHS
2 stops10h 19mAmerican Airlines
Wed 8/206:00 amCHS - HYA
2 stops8h 04mAmerican Airlines
Deal found 7/31$331
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/222:03 pmMVY - CHS
1 stop6h 37mAmerican Airlines
Tue 8/266:38 amCHS - MVY
1 stop5h 24mAmerican Airlines
Deal found 7/30$372
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2111:44 amMVY - CLT
1 stop20h 32mDelta
Mon 8/257:59 pmCLT - MVY
1 stop18h 41mDelta
Deal found 7/29$393
This Priceline deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1510:16 amMVY - SAV
1 stop7h 14mJetBlue
Tue 8/199:56 amSAV - MVY
1 stop6h 05mJetBlue
Deal found 7/31$412
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2311:01 amACK - CHS
2 stops7h 59mAmerican Airlines
Tue 8/266:00 amCHS - ACK
1 stop5h 54mAmerican Airlines
Deal found 7/29$422
This JetBlue deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2211:23 amMVY - CHS
1 stop6h 41mJetBlue
Tue 8/2611:00 amCHS - MVY
1 stop5h 01mJetBlue
Deal found 7/31$459
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/222:03 pmMVY - MYR
2 stops9h 08mAmerican Airlines
Mon 8/2510:53 amMYR - MVY
1 stop4h 44mAmerican Airlines
Deal found 7/29$493
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/211:41 pmACK - CLT
1 stop21h 28mAmerican Airlines
Sat 8/239:00 amCLT - ACK
Nonstop2h 11mAmerican Airlines
Deal found 7/29$507
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/152:03 pmMVY - SAV
2 stops8h 57mAmerican Airlines
Sun 8/175:00 amSAV - MVY
2 stops12h 16mAmerican Airlines
Deal found 7/29$517

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cape Cod and the Islands to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Cape Cod and the Islands to South Carolina that are best for you.

Fly from

Cape Cod and the Islands

Fly to

South Carolina

Route

Depart

Return

Price

West TisburyCharleston

MVY - CHS

MVYCHS

West Tisbury Martha's Vineyard

Wed 8/20

2:13 pm-9:22 pm

1 stop7h 09m

Charleston

Tue 8/26

6:00 am-11:04 am

1 stop5h 04m

$206

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Fri 9/12

10:16 am-5:45 pm

1 stop7h 29m

Charleston

Mon 9/15

6:40 pm-9:31 am

1 stop14h 51m

$315

NantucketCharlotte

ACK - CLT

ACKCLT

Nantucket Memorial

Thu 8/21

3:26 pm-5:13 pm

1 stop25h 47m

Charlotte Douglas

Sat 8/23

7:37 pm-2:46 pm

1 stop19h 09m

$325

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Sat 8/16

1:40 pm-11:59 pm

2 stops10h 19m

Charleston

Wed 8/20

6:00 am-2:04 pm

2 stops8h 04m

$331

West TisburyCharleston

MVY - CHS

MVYCHS

West Tisbury Martha's Vineyard

Fri 8/22

2:03 pm-8:40 pm

1 stop6h 37m

Charleston

Tue 8/26

6:38 am-12:02 pm

1 stop5h 24m

$372

West TisburyCharlotte

MVY - CLT

MVYCLT

West Tisbury Martha's Vineyard

Thu 8/21

11:44 am-8:16 am

1 stop20h 32m

Charlotte Douglas

Mon 8/25

7:59 pm-2:40 pm

1 stop18h 41m

$393

West TisburySavannah

MVY - SAV

MVYSAV

West Tisbury Martha's Vineyard

Fri 8/15

10:16 am-5:30 pm

1 stop7h 14m

Savannah/Hilton Head

Tue 8/19

9:56 am-4:01 pm

1 stop6h 05m

$412

NantucketCharleston

ACK - CHS

ACKCHS

Nantucket Memorial

Sat 8/23

11:01 am-7:00 pm

2 stops7h 59m

Charleston

Tue 8/26

6:00 am-11:54 am

1 stop5h 54m

$422

West TisburyCharleston

MVY - CHS

MVYCHS

West Tisbury Martha's Vineyard

Fri 8/22

11:23 am-6:04 pm

1 stop6h 41m

Charleston

Tue 8/26

11:00 am-4:01 pm

1 stop5h 01m

$459

West TisburyMyrtle Beach

MVY - MYR

MVYMYR

West Tisbury Martha's Vineyard

Fri 8/22

2:03 pm-11:11 pm

2 stops9h 08m

Myrtle Beach Intl

Mon 8/25

10:53 am-3:37 pm

1 stop4h 44m

$493

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 42 results
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Best time to book a flight from Cape Cod and the Islands to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Cape Cod and the Islands with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cape Cod and the Islands to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 31, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and JetBlue from Cape Cod and the Islands to South Carolina by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,900 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
JetBlue
7.3
Good
2,914 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Cape Cod and the Islands to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Cape Cod and the Islands to South Carolina one-way?

    $103 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and JetBlue, with prices starting from $109 and $137, respectively.

  • Can I find deals for flights from Cape Cod and the Islands to South Carolina that include hotel bookings?

    Yes. In addition to deals on Cape Cod and the Islands to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cape Cod and the Islands to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Cod and the Islands to South Carolina.

  • Can I find deals for business class flights from Cape Cod and the Islands to South Carolina?

    Yes. Cheapflights offers flight deals from Cape Cod and the Islands to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cape Cod and the Islands to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Cape Cod and the Islands to South Carolina (average of $217). Flying from Cape Cod and the Islands to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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