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$123+ Cheap flights from Cape Cod and the Islands to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/29. Fares are subject to change and may not be available on all flights or dates of travel.
ACK — CHS
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from Cape Cod and the Islands to South Carolina

Keep the following information in mind while searching for Cape Cod and the Islands to South Carolina flight deals. Data was last updated April 30, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$206
(Delta)

One-way from

$123
(Delta)

Popular in

April

Cheapest in

February

Average price

$279
Provider with most accurate pricing for Boston Logan Intl-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Boston Logan Intl-Myrtle Beach Intl flights.
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From Cape Cod and the Islands to South Carolina
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One-way flight from Cape Cod and the Islands to South Carolina
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Highest demand for flights based on searches. 15% potential increase in price ($33 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Cape Cod and the Islands to South Carolina

Cheapest flights from Cape Cod and the Islands to South Carolina
Explore the most affordable flight options available from Cape Cod and the Islands to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/264:45 pmACK - CLT
1 stop5h 07mDelta
Mon 6/3011:43 amCLT - ACK
1 stop4h 22mDelta
Deal found 4/29$206
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/93:23 pmMVY - CLT
1 stop6h 39mDelta
Tue 7/159:00 amCLT - MVY
1 stop5h 40mDelta
Deal found 4/29$256
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/411:55 amMVY - MYR
1 stop4h 49mDelta
Tue 7/86:00 amMYR - MVY
2 stops8h 40mDelta
Deal found 4/28$332
This JetBlue deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2212:26 pmMVY - SAV
1 stop4h 51mJetBlue
Sun 7/2711:25 amSAV - MVY
1 stop4h 36mJetBlue
Deal found 4/28$332
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2612:15 pmACK - CLT
2 stops9h 09mAmerican Airlines
Mon 6/309:21 amCLT - ACK
1 stop7h 35mAmerican Airlines
Deal found 4/29$400
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2411:40 amMVY - SAV
1 stop6h 14mDelta
Tue 5/276:00 amSAV - MVY
1 stop5h 32mDelta
Deal found 4/28$427
This JetBlue deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/111:20 amMVY - CHS
1 stop6h 44mJetBlue
Sun 8/311:00 amCHS - MVY
1 stop5h 01mJetBlue
Deal found 4/29$525
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2611:08 amACK - CLT
2 stops12h 49mUnited Airlines
Mon 6/306:00 amCLT - ACK
2 stops9h 10mUnited Airlines
Deal found 4/29$573
This JetBlue deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2111:40 amPVC - CHS
1 stop5h 20mJetBlue
Sat 5/2411:44 amCHS - PVC
1 stop4h 06mJetBlue
Deal found 4/28$595
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2312:15 pmMVY - CHS
1 stop5h 15mDelta
Mon 5/266:00 amCHS - MVY
1 stop5h 32mDelta
Deal found 4/29$626
This JetBlue deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/21:55 pmHYA - CHS
1 stop6h 00mJetBlue
Sat 5/311:45 amCHS - HYA
1 stop7h 53mJetBlue
Deal found 4/29$717
This JetBlue Airways deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/144:50 pmMVY - CHS
1 stop24h 10mMultiple Airlines
Sun 5/188:45 pmCHS - MVY
1 stop18h 25mMultiple Airlines
Deal found 4/29$926

Cheapflights Fare Finder

Customize your flight search to find flights from Cape Cod and the Islands to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Cape Cod and the Islands to South Carolina that are best for you.

Fly from

Cape Cod and the Islands

Fly to

South Carolina

Route

Depart

Return

Price

NantucketCharlotte

ACK - CLT

ACKCLT

Nantucket Memorial

Thu 6/26

4:45 pm-9:52 pm

1 stop5h 07m

Charlotte Douglas

Mon 6/30

11:43 am-4:05 pm

1 stop4h 22m

$206

West TisburyCharlotte

MVY - CLT

MVYCLT

West Tisbury Martha's Vineyard

Wed 7/9

3:23 pm-10:02 pm

1 stop6h 39m

Charlotte Douglas

Tue 7/15

9:00 am-2:40 pm

1 stop5h 40m

$256

West TisburySavannah

MVY - SAV

MVYSAV

West Tisbury Martha's Vineyard

Tue 7/22

12:26 pm-5:17 pm

1 stop4h 51m

Savannah/Hilton Head

Sun 7/27

11:25 am-4:01 pm

1 stop4h 36m

$332

West TisburyMyrtle Beach

MVY - MYR

MVYMYR

West Tisbury Martha's Vineyard

Fri 7/4

11:55 am-4:44 pm

1 stop4h 49m

Myrtle Beach Intl

Tue 7/8

6:00 am-2:40 pm

2 stops8h 40m

$332

NantucketCharlotte

ACK - CLT

ACKCLT

Nantucket Memorial

Thu 6/26

12:15 pm-9:24 pm

2 stops9h 09m

Charlotte Douglas

Mon 6/30

9:21 am-4:56 pm

1 stop7h 35m

$400

West TisburySavannah

MVY - SAV

MVYSAV

West Tisbury Martha's Vineyard

Sat 5/24

11:40 am-5:54 pm

1 stop6h 14m

Savannah/Hilton Head

Tue 5/27

6:00 am-11:32 am

1 stop5h 32m

$427

West TisburyCharleston

MVY - CHS

MVYCHS

West Tisbury Martha's Vineyard

Fri 8/1

11:20 am-6:04 pm

1 stop6h 44m

Charleston

Sun 8/3

11:00 am-4:01 pm

1 stop5h 01m

$525

NantucketCharlotte

ACK - CLT

ACKCLT

Nantucket Memorial

Thu 6/26

11:08 am-11:57 pm

2 stops12h 49m

Charlotte Douglas

Mon 6/30

6:00 am-3:10 pm

2 stops9h 10m

$573

ProvincetownCharleston

PVC - CHS

PVCCHS

Provincetown

Wed 5/21

11:40 am-5:00 pm

1 stop5h 20m

Charleston

Sat 5/24

11:44 am-3:50 pm

1 stop4h 06m

$595

West TisburyCharleston

MVY - CHS

MVYCHS

West Tisbury Martha's Vineyard

Fri 5/23

12:15 pm-5:30 pm

1 stop5h 15m

Charleston

Mon 5/26

6:00 am-11:32 am

1 stop5h 32m

$626

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 22 results
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Best time to book a flight from Cape Cod and the Islands to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Cape Cod and the Islands with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cape Cod and the Islands to South Carolina

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 30, 2025.
To help decide which airline to fly from Cape Cod and the Islands to South Carolina, see what other customers have to say about Delta, United Airlines and JetBlue. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,929 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,929 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
JetBlue
7.3
Good
2,922 reviews
Delta
8.0
Very good
7,929 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,929 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Cape Cod and the Islands to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Cape Cod and the Islands to South Carolina one-way?

    $123 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on JetBlue and American Airlines, with prices starting from $223 and $244, respectively.

  • Can I find deals for flights from Cape Cod and the Islands to South Carolina that include hotel bookings?

    Yes. In addition to deals on Cape Cod and the Islands to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cape Cod and the Islands to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cape Cod and the Islands to South Carolina.

  • Can I find deals for business class flights from Cape Cod and the Islands to South Carolina?

    Yes. Cheapflights offers flight deals from Cape Cod and the Islands to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cape Cod and the Islands to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Cape Cod and the Islands to South Carolina (average of $217). Flying from Cape Cod and the Islands to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Cape Cod and the Islands to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Cape Cod and the Islands to South Carolina

Discover the top airline that operate flights from Cape Cod and the Islands to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$263Average$357FlexibilityNo cancel feeOn-time62%

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