Cape Cod and the Islands

$180+ Cheap flights from South Carolina to Cape Cod and the Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ACK
Jun 16 — Jun 231
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Cheap flight deals from South Carolina to Cape Cod and the Islands

Cheapest flights from South Carolina to Cape Cod and the Islands
Explore the most affordable flight options available from South Carolina to Cape Cod and the Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 17, 2026.

This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:15 am
CHS
-
ACK
2 stops9h 04m
Delta
Tue 6/94:40 pm
ACK
-
CHS
1 stop5h 23m
Delta
Deal found 5/12$334
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:57 am
CLT
-
ACK
1 stop4h 42m
Delta
Sat 7/43:20 pm
ACK
-
CLT
1 stop5h 42m
Delta
Deal found 5/16$359
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:00 am
CHS
-
ACK
1 stop4h 26m
Delta
Wed 6/244:40 pm
ACK
-
CHS
1 stop5h 23m
Delta
Deal found 5/12$360
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
CHS
-
MVY
1 stop10h 54m
American Airlines
Tue 8/115:24 pm
MVY
-
CHS
1 stop17h 12m
American Airlines
Deal found 5/13$368
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/239:57 am
CLT
-
ACK
1 stop4h 42m
Delta
Tue 6/304:40 pm
ACK
-
CLT
1 stop4h 53m
Delta
Deal found 5/12$372
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:00 am
CHS
-
ACK
2 stops9h 42m
American Airlines
Tue 6/233:34 pm
ACK
-
CHS
2 stops8h 13m
American Airlines
Deal found 5/13$376
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:30 am
CLT
-
ACK
2 stops9h 09m
Delta
Tue 6/2312:06 pm
ACK
-
CLT
1 stop7h 26m
Delta
Deal found 5/16$378
This JetBlue deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2911:00 am
CHS
-
ACK
1 stop4h 23m
JetBlue
Wed 9/212:02 pm
ACK
-
CHS
1 stop7h 17m
JetBlue
Deal found 5/13$386
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
SAV
-
MVY
1 stop5h 02m
Delta
Wed 7/111:42 am
MVY
-
SAV
1 stop6h 30m
Delta
Deal found 5/13$389
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:17 am
CLT
-
ACK
1 stop6h 16m
American Airlines
Sat 8/2212:11 pm
ACK
-
CLT
Nonstop2h 25m
American Airlines
Deal found 5/14$390
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/299:35 am
CLT
-
MVY
1 stop5h 24m
Delta
Tue 8/411:53 am
MVY
-
CLT
1 stop4h 30m
Delta
Deal found 5/12$392
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:57 am
CLT
-
ACK
1 stop4h 42m
Delta
Fri 7/312:06 pm
ACK
-
CLT
1 stop7h 26m
Delta
Deal found 5/16$393

Find flight deals from South Carolina to Cape Cod and the Islands

Keep the following information in mind while searching for South Carolina to Cape Cod and the Islands flight deals. Data was last updated May 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$334
(Delta)

One-way from

$180
(American Airlines)

Popular in

December

Cheapest in

March

Average price

$289
Provider with most accurate pricing for Myrtle Beach Intl-Boston Logan Intl flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Boston Logan Intl flights.
From South Carolina to Cape Cod and the Islands
One-way flight from South Carolina to Cape Cod and the Islands
Highest demand for flights based on searches. 31% potential increase in price ($106 potential increase over avg. RT price).
Cheapest flight prices on average. 7% potential price decrease ($16 potential savings vs. average RT price).
Average for round-trip flights in May 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cape Cod and the Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
Use the filters below to find and compare flights from South Carolina to Cape Cod and the Islands that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonNantucket

CHS - ACK

CHSACK

Charleston

Tue 6/2

5:15 am-2:19 pm

2 stops9h 04m

Nantucket Memorial

Tue 6/9

4:40 pm-12:36 am

2 stops7h 56m

$339

CharlestonNantucket

CHS - ACK

CHSACK

Charleston

Mon 6/22

7:00 am-11:26 am

1 stop4h 26m

Nantucket Memorial

Wed 6/24

4:40 pm-10:03 pm

1 stop5h 23m

$360

CharlestonWest Tisbury

CHS - MVY

CHSMVY

Charleston

Wed 8/5

6:00 am-4:54 pm

1 stop10h 54m

West Tisbury Martha's Vineyard

Tue 8/11

5:24 pm-10:36 am

1 stop17h 12m

$368

CharlestonNantucket

CHS - ACK

CHSACK

Charleston

Sat 6/20

5:00 am-3:22 pm

2 stops10h 22m

Nantucket Memorial

Tue 6/23

11:11 am-3:43 pm

1 stop4h 32m

$371

CharlestonWest Tisbury

CHS - MVY

CHSMVY

Charleston

Wed 6/24

7:00 am-11:02 am

1 stop4h 02m

West Tisbury Martha's Vineyard

Wed 7/1

11:42 am-5:41 pm

1 stop5h 59m

$380

CharlestonWest Tisbury

CHS - MVY

CHSMVY

Charleston

Wed 6/10

6:00 am-12:38 pm

1 stop6h 38m

West Tisbury Martha's Vineyard

Wed 6/17

3:43 pm-12:36 am

2 stops8h 53m

$386

CharlotteNantucket

CLT - ACK

CLTACK

Charlotte Douglas

Wed 6/24

7:03 am-11:26 am

1 stop4h 23m

Nantucket Memorial

Mon 6/29

12:06 pm-7:32 pm

1 stop7h 26m

$406

CharlotteWest Tisbury

CLT - MVY

CLTMVY

Charlotte Douglas

Tue 6/30

6:00 am-12:38 pm

1 stop6h 38m

West Tisbury Martha's Vineyard

Mon 7/13

11:42 am-4:23 pm

1 stop4h 41m

$439

CharlotteWest Tisbury

CLT - MVY

CLTMVY

Charlotte Douglas

Tue 6/23

6:00 am-12:38 pm

1 stop6h 38m

West Tisbury Martha's Vineyard

Mon 6/29

11:42 am-4:26 pm

1 stop4h 44m

$439

GreenvilleWest Tisbury

GSP - MVY

GSPMVY

Greenville

Thu 6/25

6:14 am-1:21 pm

1 stop7h 07m

West Tisbury Martha's Vineyard

Mon 6/29

12:24 pm-10:38 pm

2 stops10h 14m

$442

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/12

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Cape Cod and the Islands

Have a flexible travel schedule? Discover the best time to fly to Cape Cod and the Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Cape Cod and the Islands
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cape Cod and the Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from South Carolina to Cape Cod and the Islands?

    For as low as $722, Delta can have you in Cape Cod and the Islands from South Carolina in 6h 06m. Airlines will cover a distance of 830 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from South Carolina to Cape Cod and the Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cape Cod and the Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cape Cod and the Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cape Cod and the Islands.

  • Can I find deals for business class flights from South Carolina to Cape Cod and the Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cape Cod and the Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Cape Cod and the Islands

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from South Carolina to Cape Cod and the Islands

Discover the top 2 airlines that operate flights from South Carolina to Cape Cod and the Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$157Average$435FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$206Average$331FlexibilityNo cancel feeOn-time71%

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