South Carolina

$209+ Cheap flights from Appleton (ATW) to South Carolina

ATW — CHS
Dec 10 — Dec 171
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Cheap flight deals from Appleton to South Carolina

Cheapest flights from Appleton to South Carolina

Sat 12/122:39 pm -
1 stop5h 32m
Tue 12/156:15 am -
1 stop6h 47m
Deal found 11/8$349
Fri 12/411:28 am -
1 stop5h 47m
Sun 12/67:05 am -
1 stop4h 53m
Deal found 11/6$349
Wed 12/165:18 am -
1 stop7h 15m
Mon 12/213:39 pm -
1 stop7h 43m
Deal found 11/5$352
Sat 12/127:04 am -
2 stops10h 13m
Tue 12/156:00 am -
1 stop5h 58m
Deal found 11/8$354
Wed 12/27:56 am -
1 stop4h 28m
Wed 12/98:07 am -
2 stops10h 48m
Deal found 11/7$357
Thu 12/105:30 am -
1 stop5h 00m
Sun 12/137:15 am -
1 stop4h 43m
Deal found 11/9$359
Mon 11/235:30 am -
1 stop6h 45m
Sat 11/285:40 am -
2 stops7h 12m
Deal found 11/7$369
Sun 12/139:46 am -
1 stop21h 17m
Wed 12/162:57 pm -
1 stop26h 48m
Deal found 11/8$370
Wed 12/25:18 am -
1 stop7h 15m
Wed 12/92:18 pm -
2 stops7h 38m
Deal found 11/10$374
Thu 12/35:18 am -
1 stop7h 15m
Sun 12/611:26 am -
1 stop7h 41m
Deal found 11/6$377
Sat 11/216:05 am -
1 stop7h 09m
Mon 11/304:11 pm -
1 stop7h 06m
Deal found 11/6$384
Sun 12/2011:39 am -
1 stop5h 24m
Sat 12/266:43 pm -
1 stop6h 16m
Deal found 11/10$399

Find flight deals from Appleton to South Carolina

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$349
(Delta)

One-way from

$209
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$369
Provider with most accurate pricing for Appleton Intl-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Appleton Intl-Myrtle Beach Intl flights.
From Appleton Intl to South Carolina
One-way flight from Appleton Intl to South Carolina
Highest demand for flights based on searches. 6% potential increase in price ($28 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Appleton to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

AppletonMyrtle Beach

ATW Appleton Intl - MYR Myrtle Beach Intl

ATWMYR

Appleton Intl

Mon 11/30

9:51 am-9:55 am

1 stop23h 04m

Myrtle Beach Intl

Wed 12/31

12:00 am-11:00 pm

Nonstop0h 00m

$209

AppletonColumbia

ATW Appleton Intl - CAE Columbia Metropolitan

ATWCAE

Appleton Intl

Mon 4/26

5:29 am-12:27 pm

1 stop5h 58m

Columbia Metropolitan

Sat 5/1

5:10 pm-9:58 pm

1 stop5h 48m

$349

AppletonColumbia

ATW Appleton Intl - CAE Columbia Metropolitan

ATWCAE

Appleton Intl

Sun 4/25

5:29 am-12:27 pm

1 stop5h 58m

Columbia Metropolitan

Sat 5/1

5:10 pm-9:58 pm

1 stop5h 48m

$349

AppletonColumbia

ATW Appleton Intl - CAE Columbia Metropolitan

ATWCAE

Appleton Intl

Thu 4/15

5:29 am-11:18 am

1 stop4h 49m

Columbia Metropolitan

Mon 4/19

5:10 pm-9:58 pm

1 stop5h 48m

$349

AppletonColumbia

ATW Appleton Intl - CAE Columbia Metropolitan

ATWCAE

Appleton Intl

Wed 4/28

5:29 am-12:27 pm

1 stop5h 58m

Columbia Metropolitan

Sun 5/2

5:10 pm-9:58 pm

1 stop5h 48m

$349

AppletonCharleston

ATW Appleton Intl - CHS Charleston

ATWCHS

Appleton Intl

Wed 2/3

8:02 am-1:46 pm

1 stop4h 44m

Charleston

Sat 2/6

12:36 pm-7:19 pm

1 stop7h 43m

$359

AppletonCharleston

ATW Appleton Intl - CHS Charleston

ATWCHS

Appleton Intl

Tue 1/12

8:02 am-1:46 pm

1 stop4h 44m

Charleston

Sat 1/16

9:46 am-4:06 pm

1 stop7h 20m

$359

AppletonCharleston

ATW Appleton Intl - CHS Charleston

ATWCHS

Appleton Intl

Sun 12/20

11:01 am-6:02 pm

1 stop6h 01m

Charleston

Sun 12/27

6:00 pm-10:22 pm

1 stop5h 22m

$359

AppletonCharleston

ATW Appleton Intl - CHS Charleston

ATWCHS

Appleton Intl

Sat 4/17

5:29 am-11:26 am

1 stop4h 57m

Charleston

Fri 4/23

5:55 pm-9:58 pm

1 stop5h 03m

$359

AppletonMyrtle Beach

ATW Appleton Intl - MYR Myrtle Beach Intl

ATWMYR

Appleton Intl

Thu 1/28

5:00 am-5:48 pm

2 stops11h 48m

Myrtle Beach Intl

Tue 2/2

11:27 am-7:19 pm

2 stops8h 52m

$362

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/8

Showing 1-10 of 38 resultsSorted by cheapest first
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Best time to book a flight from Appleton to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Appleton with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Appleton to South Carolina

What is the cheapest month to book a flight from Appleton to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Appleton to South Carolina (average of $317). Flying from Appleton to South Carolina in June is currently the most expensive (average of $477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Appleton to South Carolina?

Airfare is typical for this route at the moment.
Appleton to South Carolina flights typically cost between $322 and $397 in January.
The cheapest round-trip price found within the last 5 days was $359 on United Airlines (Jan 7-Jan 10).

How far ahead should I book a flight from Appleton to South Carolina?

The best time to book flights from Appleton to South Carolina is 32 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Reviews of airlines servicing South Carolina

Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Appleton to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.8

Boarding

8.1

Crew

8.5

Overall

7.8

Comfort

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Entertainment

7.8

Boarding

8.1

Crew

8.5

Overall

7.8

Comfort

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Entertainment

7.8

Boarding

8.1

Crew

8.5

Overall

7.8

Comfort

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Entertainment

7.8

Boarding

8.1

Crew

8.5

Overall

7.8

Comfort

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Related info for your journey

  • What airport do you fly from for flights from Appleton to South Carolina?

    Most people fly from Appleton Intl (ATW) if they book a flight from Appleton to South Carolina. Appleton Intl is conveniently located just 5.1 mi from Appleton’s city center.

  • How long is the flight from Appleton to South Carolina?

    For as low as $357, Delta can have you in South Carolina from Appleton in 4h 28m. Airlines will cover a distance of 892 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Appleton to South Carolina?

  • Can I find deals for flights from Appleton to South Carolina that include hotel bookings?

    Yes. In addition to deals on Appleton to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Appleton to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Appleton to South Carolina.

  • Can I find deals for business class flights from Appleton to South Carolina?

    Yes. Cheapflights offers flight deals from Appleton to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Appleton to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Appleton to South Carolina (average of $317). Flying from Appleton to South Carolina in June is currently the most expensive (average of $477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Appleton to South Carolina

Top 3 airlines flying from Appleton to South Carolina

AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$266Average$393FlexibilityNo cancel feeOn-time69%
DeltaCheapest$273Average$375FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$279Average$443FlexibilityNo cancel feeOn-time71%

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