
Keep the following information in mind while searching for Appleton to South Carolina flight deals. Data was last updated November 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $349 (Delta) |
One-way from | $209 (Kiwi.com) |
Popular in | June |
Cheapest in | February |
Average price | $369 |
Fly from
Fly to
Route
Depart
Return
AppletonMyrtle Beach
ATW Appleton Intl - MYR Myrtle Beach Intl
ATWMYR
Appleton Intl
Mon 11/30
9:51 am-9:55 am
1 stop23h 04m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
AppletonColumbia
ATW Appleton Intl - CAE Columbia Metropolitan
ATWCAE
Appleton Intl
Mon 4/26
5:29 am-12:27 pm
1 stop5h 58m
Columbia Metropolitan
Sat 5/1
5:10 pm-9:58 pm
1 stop5h 48m
AppletonColumbia
ATW Appleton Intl - CAE Columbia Metropolitan
ATWCAE
Appleton Intl
Sun 4/25
5:29 am-12:27 pm
1 stop5h 58m
Columbia Metropolitan
Sat 5/1
5:10 pm-9:58 pm
1 stop5h 48m
AppletonColumbia
ATW Appleton Intl - CAE Columbia Metropolitan
ATWCAE
Appleton Intl
Thu 4/15
5:29 am-11:18 am
1 stop4h 49m
Columbia Metropolitan
Mon 4/19
5:10 pm-9:58 pm
1 stop5h 48m
AppletonColumbia
ATW Appleton Intl - CAE Columbia Metropolitan
ATWCAE
Appleton Intl
Wed 4/28
5:29 am-12:27 pm
1 stop5h 58m
Columbia Metropolitan
Sun 5/2
5:10 pm-9:58 pm
1 stop5h 48m
AppletonCharleston
ATW Appleton Intl - CHS Charleston
ATWCHS
Appleton Intl
Wed 2/3
8:02 am-1:46 pm
1 stop4h 44m
Charleston
Sat 2/6
12:36 pm-7:19 pm
1 stop7h 43m
AppletonCharleston
ATW Appleton Intl - CHS Charleston
ATWCHS
Appleton Intl
Tue 1/12
8:02 am-1:46 pm
1 stop4h 44m
Charleston
Sat 1/16
9:46 am-4:06 pm
1 stop7h 20m
AppletonCharleston
ATW Appleton Intl - CHS Charleston
ATWCHS
Appleton Intl
Sun 12/20
11:01 am-6:02 pm
1 stop6h 01m
Charleston
Sun 12/27
6:00 pm-10:22 pm
1 stop5h 22m
AppletonCharleston
ATW Appleton Intl - CHS Charleston
ATWCHS
Appleton Intl
Sat 4/17
5:29 am-11:26 am
1 stop4h 57m
Charleston
Fri 4/23
5:55 pm-9:58 pm
1 stop5h 03m
AppletonMyrtle Beach
ATW Appleton Intl - MYR Myrtle Beach Intl
ATWMYR
Appleton Intl
Thu 1/28
5:00 am-5:48 pm
2 stops11h 48m
Myrtle Beach Intl
Tue 2/2
11:27 am-7:19 pm
2 stops8h 52m
Everything you need to know about your flight from Appleton to South Carolina
Entertainment
Boarding
Crew
Overall
Comfort
Food
Reviews
Ellen,Oct 2026
GRR - ATL
Entertainment
Boarding
Crew
Overall
Comfort
Food
Reviews
Ellen,Oct 2026
GRR - ATL
Entertainment
Boarding
Crew
Overall
Comfort
Food
Reviews
Ellen,Oct 2026
GRR - ATL
Entertainment
Boarding
Crew
Overall
Comfort
Food
Reviews
Ellen,Oct 2026
GRR - ATL
Find useful and relevant information for your journey from Appleton to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$266 | Average$393 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$273 | Average$375 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$279 | Average$443 | FlexibilityNo cancel fee | On-time71% |