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$148+ Cheap flights from Amarillo (AMA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — CHS
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
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Cheap flight deals from Amarillo to South Carolina

Cheapest flights from Amarillo to South Carolina
Explore the most affordable flight options available from Amarillo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/206:26 pmAMA - CAE
1 stop4h 42mAmerican Airlines
mié. 1/141:09 pmCAE - AMA
1 stop5h 59mAmerican Airlines
Deal found 12/9$554
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/207:35 amAMA - CAE
2 stops34h 24mUnited Airlines
mié. 1/148:00 amCAE - AMA
2 stops9h 56mUnited Airlines
Deal found 12/9$578
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/216:26 pmAMA - CAE
1 stop4h 42mAmerican Airlines
dom. 1/47:46 pmCAE - AMA
1 stop5h 08mAmerican Airlines
Deal found 12/9$604
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/206:26 pmAMA - CAE
1 stop4h 42mAmerican Airlines
dom. 1/47:46 pmCAE - AMA
1 stop5h 08mAmerican Airlines
Deal found 12/9$690
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/207:35 amAMA - CAE
2 stops25h 30mUnited Airlines
dom. 1/47:37 pmCAE - AMA
2 stops22h 22mUnited Airlines
Deal found 12/9$772
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/154:11 pmAMA - CAE
1 stop5h 20mAmerican Airlines
mié. 12/1710:10 amCAE - AMA
2 stops13h 22mAmerican Airlines
Deal found 12/10$993
This Southwest deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/139:55 amAMA - CHS
1 stop5h 55mSouthwest
lun. 12/158:25 amCHS - AMA
1 stop6h 55mSouthwest
Deal found 12/10$1,037

Find flight deals from Amarillo to South Carolina

Keep the following information in mind while searching for Amarillo to South Carolina flight deals. Data was last updated diciembre 12, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$269
(United Airlines)

One-way from

$148
(American Airlines)
Provider with most accurate pricing for Amarillo-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Amarillo-Myrtle Beach Intl flights.
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From Amarillo to South Carolina
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One-way flight from Amarillo to South Carolina
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Amarillo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from Amarillo to South Carolina that are best for you.

Fly from

Amarillo

Fly to

South Carolina

Route

Depart

Return

Price

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

mié. 1/7

12:06 pm-11:44 pm

2 stops10h 38m

Columbia Metropolitan

mié. 1/14

8:00 am-4:56 pm

2 stops9h 56m

$269

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

sáb. 1/24

7:30 am-6:55 pm

2 stops10h 25m

Columbia Metropolitan

mar. 1/27

8:00 am-4:56 pm

2 stops9h 56m

$349

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

mié. 1/7

6:15 am-12:28 pm

1 stop5h 13m

Columbia Metropolitan

mié. 1/14

6:00 am-4:14 pm

2 stops11h 14m

$405

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

sáb. 2/21

9:05 am-4:10 pm

1 stop6h 05m

Charleston

mié. 2/25

5:07 pm-10:08 pm

1 stop6h 01m

$434

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

mar. 1/20

4:47 pm-10:34 pm

1 stop4h 47m

$148

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

mié. 3/4

4:32 pm-10:25 pm

1 stop4h 53m

$176

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

mié. 3/4

9:05 am-11:44 pm

2 stops13h 39m

$181

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

mar. 1/20

5:35 pm-4:17 pm

3 stops21h 42m

$320

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Best time to book a flight from Amarillo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Amarillo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Amarillo to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated diciembre 12, 2025.
Read through reviews of airlines operating flights from Amarillo to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,050 reviews

Food

6.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Overall

7.2

Boarding

7.5

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
American Airlines
7.2
Good
11,050 reviews
American Airlines
7.2
Good
11,050 reviews

Food

6.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Overall

7.2

Boarding

7.5

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from Amarillo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Amarillo to South Carolina?

    Most people fly from Amarillo (AMA) if they book a flight from Amarillo to South Carolina. Amarillo is conveniently located just 6.9 mi from Amarillo’s city center.

  • How long is the flight from Amarillo to South Carolina?

    A quick flight from Amarillo to South Carolina can take about 5h 13m. United Airlines provides one of the quickest options available for as low as $405. The distance between Amarillo and South Carolina is about 1171 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Amarillo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Amarillo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Amarillo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Amarillo to South Carolina.

  • Can I find deals for business class flights from Amarillo to South Carolina?

    Yes. Cheapflights offers flight deals from Amarillo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Amarillo to South Carolina

Discover the top airline that operate flights from Amarillo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$318Average$557FlexibilityNo cancel feeOn-time71%

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