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$295+ Cheap flights from Amarillo (AMA) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — CHS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Amarillo to South Carolina

Keep the following information in mind while searching for Amarillo to South Carolina flight deals. Data was last updated September 11, 2025.

Round-trip from

$295
(American Airlines)
From Amarillo to South Carolina
Search Deals

Find flight deals from Amarillo to South Carolina

Cheapest flights from Amarillo to South Carolina
Explore the most affordable flight options available from Amarillo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/84:17 pmAMA - CHS
1 stop5h 07mAmerican Airlines
Thu 12/117:00 amCHS - AMA
1 stop5h 53mAmerican Airlines
Deal found 9/10$295
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/83:14 pmAMA - CHS
1 stop5h 45mUnited Airlines
Thu 12/1111:33 amCHS - AMA
2 stops12h 01mUnited Airlines
Deal found 9/10$300
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:45 pmAMA - CHS
2 stops14h 15mSouthwest
Mon 10/206:15 amCHS - AMA
2 stops8h 45mSouthwest
Deal found 9/9$475
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/178:24 pmAMA - CHS
1 stop16h 12mAmerican Airlines
Mon 10/207:00 pmCHS - AMA
1 stop15h 45mAmerican Airlines
Deal found 9/9$476
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/232:16 pmAMA - CAE
2 stops8h 22mAmerican Airlines
Tue 9/306:15 amCAE - AMA
2 stops8h 31mAmerican Airlines
Deal found 9/10$531
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/124:26 pmAMA - CAE
1 stop5h 54mAmerican Airlines
Sun 9/147:20 pmCAE - AMA
1 stop5h 35mAmerican Airlines
Deal found 9/10$564
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/173:20 pmAMA - CHS
3 stops31h 23mUnited Airlines
Mon 10/207:47 pmCHS - AMA
2 stops19h 22mUnited Airlines
Deal found 9/9$657
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/125:38 pmAMA - CAE
2 stops22h 13mUnited Airlines
Sun 9/147:35 pmCAE - AMA
2 stops27h 55mUnited Airlines
Deal found 9/10$1,091

Cheapflights Fare Finder

 
Customize your flight search to find flights from Amarillo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Amarillo to South Carolina that are best for you.

Fly from

Amarillo

Fly to

South Carolina

Route

Depart

Return

Price

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Sat 11/8

4:17 pm-10:24 pm

1 stop5h 07m

Charleston

Thu 12/11

7:00 am-11:53 am

1 stop5h 53m

$295

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Sat 11/8

3:14 pm-9:59 pm

1 stop5h 45m

Charleston

Thu 12/11

11:33 am-10:34 pm

2 stops12h 01m

$300

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Fri 10/17

6:45 pm-10:00 am

2 stops14h 15m

Charleston

Mon 10/20

6:15 am-2:00 pm

2 stops8h 45m

$475

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Fri 10/17

8:24 pm-1:36 pm

1 stop16h 12m

Charleston

Mon 10/20

7:00 pm-9:45 am

1 stop15h 45m

$476

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 3/10

5:05 am-1:20 pm

1 stop7h 15m

Charleston

Wed 3/11

7:37 pm-11:44 pm

1 stop5h 07m

$507

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Tue 9/23

2:16 pm-11:38 pm

2 stops8h 22m

Columbia Metropolitan

Tue 9/30

6:15 am-1:46 pm

2 stops8h 31m

$531

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Fri 10/17

3:20 pm-11:43 pm

3 stops31h 23m

Charleston

Mon 10/20

7:47 pm-2:09 pm

2 stops19h 22m

$657

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Thu 10/9

2:30 pm-12:25 am

2 stops8h 55m

$318

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Thu 10/9

5:00 am-1:36 pm

1 stop7h 36m

$364

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Thu 10/9

5:27 pm-11:42 pm

3 stops53h 15m

$633

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Amarillo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Amarillo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Amarillo to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Amarillo to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Food

6.4

Overall

7.2

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Food

6.4

Overall

7.2

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from Amarillo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Amarillo to South Carolina?

    Most people fly from Amarillo (AMA) if they book a flight from Amarillo to South Carolina. Amarillo is conveniently located just 6.9 mi from Amarillo’s city center.

  • How long is the flight from Amarillo to South Carolina?

    A quick flight from Amarillo to South Carolina can take about 5h 07m. American Airlines provides one of the quickest options available for as low as $295. The distance between Amarillo and South Carolina is about 1247 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Amarillo to South Carolina one-way?

    The cheapest airlines for a one-way flight from Amarillo to South Carolina are Southwest ($318), American Airlines ($364), and United Airlines ($633).

  • Can I find deals for flights from Amarillo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Amarillo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Amarillo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Amarillo to South Carolina.

  • Can I find deals for business class flights from Amarillo to South Carolina?

    Yes. Cheapflights offers flight deals from Amarillo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Amarillo to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Amarillo to South Carolina (average of $217). Flying from Amarillo to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Amarillo to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Amarillo to South Carolina

Discover the top airline that operate flights from Amarillo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$385Average$454FlexibilityNo cancel feeOn-time71%

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