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$179+ Cheap flights from Amarillo (AMA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — CHS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Amarillo to South Carolina

Cheapest flights from Amarillo to South Carolina
Explore the most affordable flight options available from Amarillo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/14:16 pmAMA - CHS
1 stop5h 18mAmerican Airlines
Thu 12/47:00 amCHS - AMA
1 stop5h 53mAmerican Airlines
Deal found 10/28$385
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/112:10 pmAMA - CHS
2 stops10h 45mSouthwest
Thu 12/46:00 amCHS - AMA
2 stops9h 20mSouthwest
Deal found 10/28$425
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amAMA - CHS
1 stop7h 11mAmerican Airlines
Mon 12/17:10 pmCHS - AMA
1 stop15h 30mAmerican Airlines
Deal found 10/27$533
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:00 amAMA - CHS
1 stop7h 26mAmerican Airlines
Mon 11/177:00 amCHS - AMA
1 stop5h 51mAmerican Airlines
Deal found 10/29$547
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/242:20 pmAMA - CHS
2 stops8h 10mSouthwest
Mon 12/16:10 amCHS - AMA
2 stops11h 20mSouthwest
Deal found 10/27$622
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/245:45 pmAMA - CAE
2 stops26h 45mUnited Airlines
Mon 12/12:50 pmCAE - AMA
2 stops21h 41mUnited Airlines
Deal found 10/27$759
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2412:05 pmAMA - CHS
2 stops21h 03mUnited Airlines
Mon 12/14:38 pmCHS - AMA
3 stops30h 56mUnited Airlines
Deal found 10/27$788
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amAMA - CAE
1 stop7h 39mAmerican Airlines
Mon 12/16:59 pmCAE - AMA
1 stop15h 41mAmerican Airlines
Deal found 10/27$823

Cheap flight deals from Amarillo to South Carolina

Keep the following information in mind while searching for Amarillo to South Carolina flight deals. Data was last updated October 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$375
(United Airlines)

One-way from

$179
(American Airlines)
Provider with most accurate pricing for Amarillo-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Amarillo-Myrtle Beach Intl flights.
Search Deals
From Amarillo to South Carolina
Search Deals
One-way flight from Amarillo to South Carolina
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Amarillo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Amarillo to South Carolina that are best for you.

Fly from

Amarillo

Fly to

South Carolina

Route

Depart

Return

Price

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Fri 1/30

3:20 pm-9:57 pm

1 stop5h 37m

Charleston

Mon 2/2

4:01 pm-9:51 pm

1 stop6h 50m

$375

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Mon 12/1

4:16 pm-10:34 pm

1 stop5h 18m

Charleston

Thu 12/4

7:00 am-11:53 am

1 stop5h 53m

$385

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Mon 12/1

12:10 pm-11:55 pm

2 stops10h 45m

Charleston

Thu 12/4

6:00 am-2:20 pm

2 stops9h 20m

$425

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 3/10

12:32 pm-5:45 pm

1 stop4h 13m

Charleston

Wed 3/11

7:37 pm-11:44 pm

1 stop5h 07m

$507

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Wed 3/25

12:32 pm-7:14 pm

1 stop5h 42m

Columbia Metropolitan

Sat 3/28

7:08 am-11:26 am

1 stop5h 18m

$582

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Mon 1/19

7:30 am-10:17 am

2 stops25h 47m

Columbia Metropolitan

Mon 2/16

7:36 pm-4:56 pm

2 stops22h 20m

$669

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Mon 1/19

5:35 pm-11:44 pm

2 stops29h 09m

Columbia Metropolitan

Thu 1/22

9:10 am-9:59 pm

2 stops13h 49m

$708

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Mon 11/24

5:45 pm-9:30 pm

2 stops26h 45m

Columbia Metropolitan

Mon 12/1

2:50 pm-11:31 am

2 stops21h 41m

$759

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Mon 11/24

6:00 am-2:39 pm

1 stop7h 39m

Columbia Metropolitan

Mon 12/1

6:59 pm-9:40 am

1 stop15h 41m

$823

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 11/18

7:00 am-2:31 pm

1 stop6h 31m

$179

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Best time to book a flight from Amarillo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Amarillo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Amarillo to South Carolina
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from Amarillo to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,030 reviews

Boarding

7.5

Comfort

7.2

Overall

7.2

Crew

8.0

Entertainment

6.9

Food

6.4

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
American Airlines
7.2
Good
11,030 reviews
American Airlines
7.2
Good
11,030 reviews

Boarding

7.5

Comfort

7.2

Overall

7.2

Crew

8.0

Entertainment

6.9

Food

6.4

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from Amarillo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Amarillo to South Carolina?

    Most people fly from Amarillo (AMA) if they book a flight from Amarillo to South Carolina. Amarillo is conveniently located just 6.9 mi from Amarillo’s city center.

  • How long is the flight from Amarillo to South Carolina?

    A quick flight from Amarillo to South Carolina can take about 5h 18m. United Airlines provides one of the quickest options available for as low as $385. The distance between Amarillo and South Carolina is about 1247 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Amarillo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Amarillo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Amarillo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Amarillo to South Carolina.

  • Can I find deals for business class flights from Amarillo to South Carolina?

    Yes. Cheapflights offers flight deals from Amarillo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Amarillo to South Carolina

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Top airline flying from Amarillo to South Carolina

Discover the top airline that operate flights from Amarillo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$318Average$444FlexibilityNo cancel feeOn-time71%

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