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$367+ Cheap flights from Amarillo (AMA) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
AMA — CHS
Apr 17 — Apr 241
Fri 4/17
Fri 4/24
1 adult, Economy
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Cheap flight deals from Amarillo to South Carolina

Cheapest flights from Amarillo to South Carolina
Explore the most affordable flight options available from Amarillo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 18, 2026.

This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/59:00 am
AMA
-
CHS
1 stop6h 11m
United Airlines
Wed 5/65:07 pm
CHS
-
AMA
1 stop6h 27m
United Airlines
Deal found 3/16$367
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/79:00 am
AMA
-
CHS
1 stop6h 11m
United Airlines
Tue 4/215:12 pm
CHS
-
AMA
1 stop6h 22m
United Airlines
Deal found 3/17$386
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/79:00 am
AMA
-
CHS
2 stops13h 59m
United Airlines
Thu 4/95:12 pm
CHS
-
AMA
1 stop6h 22m
United Airlines
Deal found 3/17$391
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:00 am
AMA
-
CHS
2 stops9h 38m
American Airlines
Tue 4/214:41 pm
CHS
-
AMA
1 stop6h 01m
American Airlines
Deal found 3/17$411
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:00 am
AMA
-
CAE
2 stops11h 16m
United Airlines
Tue 11/1710:20 am
CAE
-
AMA
2 stops12h 21m
United Airlines
Deal found 3/13$466
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/512:30 pm
AMA
-
CHS
1 stop4h 58m
American Airlines
Tue 4/214:41 pm
CHS
-
AMA
1 stop6h 01m
American Airlines
Deal found 3/17$472
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:15 am
AMA
-
CAE
1 stop6h 56m
American Airlines
Wed 4/17:44 pm
CAE
-
AMA
1 stop5h 15m
American Airlines
Deal found 3/13$487
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:04 pm
AMA
-
CAE
2 stops24h 51m
United Airlines
Sat 5/210:34 am
CAE
-
AMA
2 stops13h 00m
United Airlines
Deal found 3/16$567
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:55 am
AMA
-
CAE
2 stops9h 50m
American Airlines
Sat 5/24:15 pm
CAE
-
AMA
1 stop6h 27m
American Airlines
Deal found 3/16$572
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2812:04 pm
AMA
-
CAE
2 stops10h 40m
United Airlines
Wed 4/110:41 am
CAE
-
AMA
2 stops12h 53m
United Airlines
Deal found 3/13$603
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:07 pm
AMA
-
CAE
1 stop15h 51m
American Airlines
Sat 5/24:15 pm
CAE
-
AMA
1 stop6h 27m
American Airlines
Deal found 3/16$605
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:19 pm
AMA
-
CAE
2 stops15h 55m
United Airlines
Mon 4/207:38 pm
CAE
-
AMA
2 stops22h 02m
United Airlines
Deal found 3/16$717

Find flight deals from Amarillo to South Carolina

Keep the following information in mind while searching for Amarillo to South Carolina flight deals. Data was last updated March 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$367
(United Airlines)
Provider with most accurate pricing for Amarillo-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Amarillo-Myrtle Beach Intl flights.
Search Deals
From Amarillo to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Amarillo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Amarillo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 5/5

9:00 am-4:11 pm

1 stop6h 11m

Charleston

Wed 5/6

5:07 pm-10:34 pm

1 stop6h 27m

$367

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 4/14

7:00 am-6:35 pm

1 stop10h 35m

Charleston

Tue 4/21

1:15 pm-10:10 pm

1 stop9h 55m

$378

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Tue 4/7

9:00 am-11:59 pm

2 stops13h 59m

Charleston

Thu 4/9

6:00 am-2:26 pm

2 stops9h 26m

$396
Quickest round-trip

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Sat 3/28

7:15 am-3:11 pm

1 stop6h 56m

Columbia Metropolitan

Wed 4/1

7:44 pm-11:59 pm

1 stop5h 15m

$487

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Wed 4/22

5:19 pm-9:51 am

2 stops15h 32m

Columbia Metropolitan

Sat 5/2

10:34 am-10:34 pm

2 stops13h 00m

$567

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Sat 3/28

12:04 pm-11:44 pm

2 stops10h 40m

Columbia Metropolitan

Wed 4/1

5:35 pm-4:40 pm

3 stops24h 05m

$764

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Wed 4/22

5:19 pm-9:51 am

2 stops15h 32m

Columbia Metropolitan

Sun 5/3

7:38 pm-11:24 am

2 stops16h 46m

$848

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Tue 4/21

5:19 pm-9:51 am

2 stops15h 32m

Columbia Metropolitan

Sun 5/3

7:38 pm-11:24 am

2 stops16h 46m

$848
Cheapest one-way

AmarilloColumbia

AMA - CAE

AMACAE

Amarillo

Sat 3/28

12:04 pm-11:44 pm

2 stops10h 40m

$384
Quickest one-way

AmarilloCharleston

AMA - CHS

AMACHS

Amarillo

Thu 3/26

10:20 am-6:28 pm

1 stop7h 08m

$429

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/13

Showing 1-10 of 12 resultsSorted by cheapest first
1
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Best time to book a flight from Amarillo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Amarillo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Amarillo to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Amarillo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Amarillo to South Carolina?

    Most people fly from Amarillo (AMA) if they book a flight from Amarillo to South Carolina. Amarillo is conveniently located just 6.9 mi from Amarillo’s city center.

  • How long is the flight from Amarillo to South Carolina?

    A quick flight from Amarillo to South Carolina can take about 6h 11m. United Airlines provides one of the quickest options available for as low as $367. The distance between Amarillo and South Carolina is about 1247 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Amarillo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Amarillo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Amarillo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Amarillo to South Carolina.

  • Can I find deals for business class flights from Amarillo to South Carolina?

    Yes. Cheapflights offers flight deals from Amarillo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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