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Sicily

$305+ Cheap flights from South Carolina to Sicily

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CTA
ene. 8 — ene. 151
jue. 1/8
jue. 1/15
1 adult, Economy
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Cheap flight deals from South Carolina to Sicily

Cheapest flights from South Carolina to Sicily
Explore the most affordable flight options available from South Carolina to Sicily. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 9, 2025.

This Mytrip deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/126:50 pmCLT - CTA
2 stops21h 35mMultiple Airlines
dom. 12/145:45 amCTA - CLT
3 stops36h 19mMultiple Airlines
Deal found 12/8$1,199
This Mytrip deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1111:55 amCHS - CTA
3 stops29h 25mMultiple Airlines
sáb. 12/139:35 amCTA - CHS
2 stops31h 25mMultiple Airlines
Deal found 12/7$1,249
This FlightHub deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/247:44 pmCLT - PMO
2 stops45h 16mLufthansa
dom. 12/286:25 pmPMO - CLT
1 stop28h 30mLufthansa
Deal found 12/9$1,351
This KAYAK deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/257:44 pmCLT - CTA
2 stops15h 51mLufthansa
dom. 1/116:10 pmCTA - CLT
2 stops30h 49mLufthansa
Deal found 12/7$1,359
This KAYAK deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/242:54 pmCLT - CTA
2 stops23h 51mLufthansa
dom. 1/116:10 pmCTA - CLT
2 stops30h 49mLufthansa
Deal found 12/7$1,427
This KAYAK deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/257:44 pmCLT - CTA
2 stops15h 51mLufthansa
mar. 1/133:25 pmCTA - CLT
2 stops33h 34mLufthansa
Deal found 12/7$1,451
This KAYAK deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/242:54 pmCLT - CTA
2 stops23h 51mLufthansa
mar. 1/1311:40 amCTA - CLT
2 stops37h 19mLufthansa
Deal found 12/7$1,520
This KAYAK deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/242:54 pmCLT - CTA
2 stops23h 51mLufthansa
lun. 1/126:00 amCTA - CLT
2 stops18h 59mLufthansa
Deal found 12/7$1,603
This KAYAK deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/257:44 pmCLT - CTA
2 stops33h 01mLufthansa
lun. 1/126:00 amCTA - CLT
2 stops16h 55mLufthansa
Deal found 12/7$1,622
This Ovago deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/114:38 pmCHS - CTA
2 stops36h 37mLufthansa
sáb. 12/133:25 pmCTA - CHS
2 stops33h 36mLufthansa
Deal found 12/7$1,890
This Trip.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/246:25 pmCLT - PMO
3 stops22h 35mMultiple Airlines
dom. 12/286:10 amPMO - CLT
3 stops38h 00mMultiple Airlines
Deal found 12/9$2,141
This Ovago deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/192:54 pmCLT - PMO
2 stops14h 31mLufthansa
dom. 1/113:15 pmPMO - CLT
2 stops31h 40mLufthansa
Deal found 12/8$2,240

Find flight deals from South Carolina to Sicily

Keep the following information in mind while searching for South Carolina to Sicily flight deals. Data was last updated diciembre 9, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$516
(KLM)

One-way from

$305
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Catania Fontanarossa flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Catania Fontanarossa flights.
Search Deals
From South Carolina to Sicily
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One-way flight from South Carolina to Sicily
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Sicily that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 9, 2025.
Use the filters below to find and compare flights from South Carolina to Sicily that are best for you.

Fly from

South Carolina

Fly to

Sicily

Route

Depart

Return

Price

CharlotteCatania

CLT - CTA

CLTCTA

Charlotte Douglas

mié. 1/21

1:13 pm-2:40 pm

2 stops19h 27m

Catania Fontanarossa

mié. 1/28

3:25 pm-8:38 pm

2 stops35h 13m

$625

CharlotteCatania

CLT - CTA

CLTCTA

Charlotte Douglas

dom. 1/18

6:50 pm-7:50 pm

2 stops19h 00m

Catania Fontanarossa

dom. 1/25

6:10 pm-4:55 pm

1 stop28h 45m

$660

SavannahCatania

SAV - CTA

SAVCTA

Savannah/Hilton Head

lun. 4/20

11:45 am-7:55 am

1 stop14h 10m

Catania Fontanarossa

jue. 5/7

9:55 am-9:30 pm

1 stop17h 35m

$708

SavannahCatania

SAV - CTA

SAVCTA

Savannah/Hilton Head

dom. 4/19

7:25 am-7:55 am

1 stop18h 30m

Catania Fontanarossa

jue. 5/7

9:55 am-9:30 pm

1 stop17h 35m

$708

SavannahCatania

SAV - CTA

SAVCTA

Savannah/Hilton Head

lun. 4/20

7:25 am-7:55 am

1 stop18h 30m

Catania Fontanarossa

vie. 5/8

9:55 am-10:31 pm

1 stop18h 36m

$708

SavannahCatania

SAV - CTA

SAVCTA

Savannah/Hilton Head

mié. 4/22

11:45 am-7:55 am

1 stop14h 10m

Catania Fontanarossa

vie. 5/8

9:55 am-10:31 pm

1 stop18h 36m

$708

SavannahCatania

SAV - CTA

SAVCTA

Savannah/Hilton Head

mié. 4/22

7:25 am-7:55 am

1 stop18h 30m

Catania Fontanarossa

jue. 5/7

9:55 am-10:38 pm

2 stops18h 43m

$712

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

dom. 3/22

7:50 pm-6:20 pm

2 stops17h 30m

Palermo Punta Raisi

mar. 3/31

11:55 am-11:58 pm

2 stops18h 03m

$726

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

dom. 2/22

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

sáb. 2/28

9:45 am-4:55 pm

2 stops37h 10m

$738

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

vie. 1/23

11:12 am-11:25 pm

3 stops30h 13m

Palermo Punta Raisi

vie. 1/30

6:50 am-11:59 pm

3 stops47h 09m

$750

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/8

Showing 1-10 of 42 results
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Best time to book a flight from South Carolina to Sicily

Have a flexible travel schedule? Discover the best time to fly to Sicily from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Sicily

What is the cheapest time of day to fly from SC to SI?

Find hourly flight availability from South Carolina to Sicily. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 9, 2025.

It’s typically best to fly out from South Carolina to Sicily in the evening. Doing so could potentially save you 30% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Sicily

Get insights into the airlines that provide service to Sicily. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sicily. Reviews last updated diciembre 9, 2025.
Read reviews from past customers who have flown Lufthansa from South Carolina to Sicily. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Lufthansa
6.8
Okay
7,618 reviews

Comfort

6.8

Overall

6.8

Entertainment

6.4

Food

6.3

Crew

7.6

Boarding

7.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2024

SFO - FRA

Convenient flight to my destination. Good entertainment options on board. I was seated close to some people who had noisy children which made sleeping a bit challenging.
Lufthansa
6.8
Okay
7,618 reviews
Lufthansa
6.8
Okay
7,618 reviews

Comfort

6.8

Overall

6.8

Entertainment

6.4

Food

6.3

Crew

7.6

Boarding

7.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Dec 2024

SFO - FRA

Convenient flight to my destination. Good entertainment options on board. I was seated close to some people who had noisy children which made sleeping a bit challenging.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Sicily. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Sicily?

    Departing from South Carolina to Sicily will take you 14h 10m. The distance from South Carolina to Sicily is about 5214 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from South Carolina to Sicily that include hotel bookings?

    Yes. In addition to deals on South Carolina to Sicily flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Sicily?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Sicily.

  • Can I find deals for business class flights from South Carolina to Sicily?

    Yes. Cheapflights offers flight deals from South Carolina to Sicily by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for South Carolina to Sicily

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Sicily

Discover the top airline that operate flights from South Carolina to Sicily. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$635Average$1,459FlexibilityNo cancel feeOn-time76%

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