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Sicily

$287+ Cheap flights from South Carolina to Sicily

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CTA
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from South Carolina to Sicily

Cheapest flights from South Carolina to Sicily
Explore the most affordable flight options available from South Carolina to Sicily. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This KLM deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/242:26 pm
CLT
-
CTA
2 stops18h 14m
KLM
Tue 3/33:25 pm
CTA
-
CLT
2 stops37h 05m
KLM
Deal found 1/27$545
This Justfly.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:50 pm
CLT
-
PMO
2 stops17h 35m
Multiple Airlines
Tue 3/3111:50 am
PMO
-
CLT
2 stops18h 07m
Multiple Airlines
Deal found 1/27$608
This KLM deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:30 pm
CLT
-
CTA
2 stops17h 20m
KLM
Mon 4/610:35 pm
CTA
-
CLT
2 stops23h 51m
KLM
Deal found 1/27$609
This KLM deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:59 pm
CLT
-
CTA
1 stop29h 56m
Multiple Airlines
Wed 5/279:55 am
CTA
-
CLT
1 stop18h 28m
Multiple Airlines
Deal found 1/27$613
This KLM deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:20 pm
CLT
-
CTA
1 stop34h 35m
KLM
Wed 5/279:55 am
CTA
-
CLT
1 stop18h 28m
KLM
Deal found 1/28$614
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:40 pm
CLT
-
CTA
1 stop17h 05m
Lufthansa
Tue 10/66:00 am
CTA
-
CLT
1 stop16h 45m
Lufthansa
Deal found 1/27$669
This FlightHub deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:50 pm
CLT
-
PMO
2 stops17h 35m
SWISS
Sat 2/289:45 am
PMO
-
CLT
2 stops37h 10m
SWISS
Deal found 1/28$669
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:40 am
CLT
-
CTA
2 stops26h 50m
SWISS
Tue 10/68:35 pm
CTA
-
CLT
2 stops26h 32m
SWISS
Deal found 1/27$687
This KAYAK deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:50 pm
CLT
-
PMO
2 stops17h 35m
Multiple Airlines
Sat 2/2812:10 pm
PMO
-
CLT
1 stop34h 45m
Multiple Airlines
Deal found 1/27$692
This Gotogate deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:30 am
CLT
-
CTA
2 stops19h 45m
Multiple Airlines
Tue 10/66:00 am
CTA
-
CLT
1 stop16h 45m
Multiple Airlines
Deal found 1/29$693
This Booking.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:15 pm
CHS
-
CTA
2 stops42h 30m
Multiple Airlines
Wed 9/911:50 am
CTA
-
CHS
2 stops52h 43m
Multiple Airlines
Deal found 1/28$753
This KAYAK deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/272:48 pm
CHS
-
CTA
2 stops14h 27m
Multiple Airlines
Fri 3/68:50 am
CTA
-
CHS
2 stops16h 10m
Multiple Airlines
Deal found 1/28$754

Find flight deals from South Carolina to Sicily

Keep the following information in mind while searching for South Carolina to Sicily flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$545
(KLM)

One-way from

$287
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Catania Fontanarossa flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Catania Fontanarossa flights.
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From South Carolina to Sicily
Search Deals
One-way flight from South Carolina to Sicily
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Sicily that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from South Carolina to Sicily that are best for you.

Fly from

South Carolina

Fly to

Sicily

Route

Depart

Return

Price

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 3/22

7:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Tue 3/31

11:50 am-11:57 pm

2 stops18h 07m

$608

CharlotteCatania

CLT - CTA

CLTCTA

Charlotte Douglas

Tue 3/31

2:30 pm-1:50 pm

2 stops17h 20m

Catania Fontanarossa

Mon 4/6

10:35 pm-4:26 pm

2 stops23h 51m

$609

CharlotteCatania

CLT - CTA

CLTCTA

Charlotte Douglas

Wed 5/6

7:59 pm-7:55 am

1 stop29h 56m

Catania Fontanarossa

Wed 5/27

9:55 am-10:23 pm

1 stop18h 28m

$613

CharlotteCatania

CLT - CTA

CLTCTA

Charlotte Douglas

Wed 5/6

3:20 pm-7:55 am

1 stop34h 35m

Catania Fontanarossa

Wed 5/27

10:15 am-10:02 pm

2 stops17h 47m

$623

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 2/22

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sat 2/28

9:45 am-4:55 pm

2 stops37h 10m

$669

CharlestonCatania

CHS - CTA

CHSCTA

Charleston

Fri 2/27

2:48 pm-11:15 am

2 stops14h 27m

Catania Fontanarossa

Fri 3/6

8:50 am-7:00 pm

2 stops16h 10m

$754

CharlotteCatania

CLT - CTA

CLTCTA

Charlotte Douglas

Tue 2/24

6:50 pm-5:00 pm

2 stops16h 10m

Catania Fontanarossa

Tue 3/3

6:00 am-8:57 pm

2 stops20h 57m

$788

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Wed 4/1

10:48 pm-11:05 am

2 stops54h 17m

Palermo Punta Raisi

Tue 4/7

12:15 pm-4:47 pm

2 stops34h 32m

$857

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Wed 3/4

7:50 am-11:05 am

2 stops21h 15m

Palermo Punta Raisi

Sun 3/8

10:05 am-8:57 pm

2 stops39h 52m

$876

CharlottePalermo

CLT - PMO

CLTPMO

Charlotte Douglas

Sun 2/15

6:50 pm-6:25 pm

2 stops17h 35m

Palermo Punta Raisi

Sat 2/21

12:15 pm-4:55 pm

2 stops34h 40m

$880

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 37 results
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Best time to book a flight from South Carolina to Sicily

Have a flexible travel schedule? Discover the best time to fly to Sicily from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Sicily
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Sicily

Get insights into the airlines that provide service to Sicily. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sicily. Reviews last updated January 29, 2026.
Read reviews from past customers who have flown Lufthansa from South Carolina to Sicily. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Lufthansa
6.8
Okay
7,754 reviews

Boarding

7.0

Food

6.3

Overall

6.8

Crew

7.6

Entertainment

6.4

Comfort

6.8

Reviews

1 / 20
6.0
Good

Anonymous,Dec 2025

SFO - MUC

The coordination between United and Lufthansa teams is poor and confusing.
Lufthansa
6.8
Okay
7,754 reviews
Lufthansa
6.8
Okay
7,754 reviews

Boarding

7.0

Food

6.3

Overall

6.8

Crew

7.6

Entertainment

6.4

Comfort

6.8

Reviews

1 / 20
6.0
Good

Anonymous,Dec 2025

SFO - MUC

The coordination between United and Lufthansa teams is poor and confusing.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Sicily. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Sicily?

    Departing from South Carolina to Sicily will take you 17h 20m. The distance from South Carolina to Sicily is about 5079 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from South Carolina to Sicily that include hotel bookings?

    Yes. In addition to deals on South Carolina to Sicily flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Sicily?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Sicily.

  • Can I find deals for business class flights from South Carolina to Sicily?

    Yes. Cheapflights offers flight deals from South Carolina to Sicily by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for South Carolina to Sicily

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Sicily

Discover the top airline that operate flights from South Carolina to Sicily. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$635Average$1,459FlexibilityNo cancel feeOn-time76%

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