$1,546+ Cheap flights from Myrtle Beach (MYR) to Sicily
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CTA
Jan 17 — Jan 241
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Sicily
Best flights from Myrtle Beach to SicilyDiscover carefully curated flight deals from Myrtle Beach to Sicily that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.
Discover carefully curated flight deals from Myrtle Beach to Sicily that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.
This Ovago deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/23:11 pmMYR - PMO
2 stops21h 54mBritish Airways
Sat 4/116:55 pmPMO - MYR
2 stops45h 26mBritish Airways
Deal found 12/16![British Airways logo]()
$1,546
This Air Canada deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/212:07 pmMYR - PMO
3 stops23h 18mAir Canada
Sat 4/1110:05 amPMO - MYR
3 stops31h 08mAir Canada
Deal found 12/16![Air Canada logo]()
$2,559
Find flight deals from Myrtle Beach to Sicily
Keep the following information in mind while searching for Myrtle Beach to Sicily flight deals. Data was last updated December 18, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $1,546 (Ovago) |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Sicily that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Sicily that are best for you.
Fly from
Myrtle Beach
Fly to
Sicily
Route
Depart
Return
Price
Myrtle BeachPalermo
MYR - PMO
MYRPMO
Myrtle Beach Intl
Thu 4/2
3:11 pm-7:05 pm
2 stops21h 54m
Palermo Punta Raisi
Sat 4/11
6:55 pm-10:21 am
2 stops45h 26m
$1,546
Myrtle BeachPalermo
MYR - PMO
MYRPMO
Myrtle Beach Intl
Thu 4/2
12:07 pm-5:25 pm
3 stops23h 18m
Palermo Punta Raisi
Sat 4/11
10:05 am-11:13 am
3 stops31h 08m
$2,559
Best time to book a flight from Myrtle Beach to Sicily
Have a flexible travel schedule? Discover the best time to fly to Sicily from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Sicily
What is the cheapest time of day to fly from MYR to SI?
Find hourly flight availability from Myrtle Beach to Sicily. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.
A simple way to save on the total cost of your ticket is to fly from Myrtle Beach to Sicily in the evening. If you’re flexible enough to do this you can expect to save up to 58% on your trip compared to booking a flight in the afternoon.