Sicily

$452+ Cheap flights from Missouri to Sicily

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CTA
Jul 8 — Jul 151
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Cheap flight deals from Missouri to Sicily

Keep the following information in mind while searching for Missouri to Sicily flight deals. Data was last updated July 3, 2025.

Round-trip from

$867
(KAYAK)

One-way from

$452
(Kiwi.com)
From Missouri to Sicily
One-way flight from Missouri to Sicily

Find flight deals from Missouri to Sicily

Cheapest flights from Missouri to Sicily
Explore the most affordable flight options available from Missouri to Sicily. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Lufthansa deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/123:50 pmSTL - CTA
2 stops42h 45mLufthansa
Sun 11/166:20 pmCTA - STL
2 stops36h 24mLufthansa
Deal found 6/30$801
This Priceline deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/276:27 pmMCI - CTA
2 stops33h 33mLufthansa
Sat 10/116:00 amCTA - MCI
2 stops24h 54mLufthansa
Deal found 6/30$1,012
This oojo deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:27 pmMCI - CTA
2 stops31h 18mTurkish Airlines
Tue 10/147:10 pmCTA - MCI
2 stops26h 10mTurkish Airlines
Deal found 7/1$1,258
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/131:30 pmSTL - CTA
2 stops17h 30mMultiple Airlines
Wed 7/169:25 amCTA - STL
3 stops31h 27mMultiple Airlines
Deal found 6/30$1,312
This Air France deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/179:56 amMCI - CTA
1 stop14h 59mAir France
Mon 7/218:55 amCTA - MCI
1 stop17h 22mAir France
Deal found 7/2$1,364
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/178:10 amMCI - CTA
2 stops16h 45mDelta
Mon 7/218:55 amCTA - MCI
2 stops21h 14mDelta
Deal found 7/1$1,369
This Air Canada deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/271:00 pmMCI - CTA
3 stops23h 55mAir Canada
Sat 10/118:45 amCTA - MCI
3 stops31h 24mAir Canada
Deal found 6/30$1,564
This oojo deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/36:27 pmMCI - PMO
2 stops40h 48mTurkish Airlines
Thu 7/109:20 amPMO - MCI
2 stops43h 11mTurkish Airlines
Deal found 7/2$1,597
This KLM deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/119:59 amMCI - CTA
1 stop14h 56mMultiple Airlines
Tue 10/149:55 amCTA - MCI
1 stop15h 43mMultiple Airlines
Deal found 7/2$1,654
This KLM deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/279:59 amMCI - CTA
1 stop14h 56mKLM
Sat 10/119:55 amCTA - MCI
1 stop15h 43mKLM
Deal found 6/30$1,809
This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/39:47 pmMCI - PMO
3 stops29h 53mMultiple Airlines
Thu 7/108:10 pmPMO - MCI
3 stops35h 02mMultiple Airlines
Deal found 7/2$1,812
This Gurufare deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/35:40 pmMCI - PMO
2 stops16h 35mLufthansa
Thu 7/109:45 amPMO - MCI
1 stop19h 31mLufthansa
Deal found 7/2$2,071

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Sicily that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Missouri to Sicily that are best for you.

Fly from

Missouri

Fly to

Sicily

Route

Depart

Return

Price

St. LouisCatania

STL - CTA

STLCTA

Lambert-St Louis

Wed 11/12

3:50 pm-5:35 pm

2 stops42h 45m

Catania Fontanarossa

Sun 11/16

6:20 pm-11:44 pm

2 stops36h 24m

$801

Kansas CityCatania

MCI - CTA

MCICTA

Kansas City

Sat 9/27

6:27 pm-11:00 am

2 stops33h 33m

Catania Fontanarossa

Sat 10/11

6:00 am-11:54 pm

2 stops24h 54m

$1,012

St. LouisCatania

STL - CTA

STLCTA

Lambert-St Louis

Sun 7/13

1:30 pm-2:00 pm

2 stops17h 30m

Catania Fontanarossa

Wed 7/16

9:25 am-9:52 am

3 stops31h 27m

$1,312

Kansas CityCatania

MCI - CTA

MCICTA

Kansas City

Thu 7/17

9:56 am-7:55 am

1 stop14h 59m

Catania Fontanarossa

Mon 7/21

8:55 am-7:17 pm

1 stop17h 22m

$1,364

Kansas CityCatania

MCI - CTA

MCICTA

Kansas City

Thu 7/17

8:10 am-7:55 am

2 stops16h 45m

Catania Fontanarossa

Mon 7/21

8:55 am-11:09 pm

2 stops21h 14m

$1,369

Kansas CityCatania

MCI - CTA

MCICTA

Kansas City

Sat 9/27

1:00 pm-7:55 pm

3 stops23h 55m

Catania Fontanarossa

Sat 10/11

8:45 am-9:09 am

3 stops31h 24m

$1,564

Kansas CityCatania

MCI - CTA

MCICTA

Kansas City

Sat 9/27

9:59 am-7:55 am

1 stop14h 56m

Catania Fontanarossa

Sat 10/11

9:55 am-6:38 pm

1 stop15h 43m

$1,809

Kansas CityPalermo

MCI - PMO

MCIPMO

Kansas City

Sat 8/16

11:25 am-7:15 am

2 stops36h 50m

Palermo Punta Raisi

Sat 8/23

9:45 am-10:26 pm

2 stops19h 41m

$9,091

St. LouisCatania

STL - CTA

STLCTA

Lambert-St Louis

Fri 8/8

7:29 pm-10:35 pm

3 stops44h 06m

$452

St. LouisCatania

STL - CTA

STLCTA

Lambert-St Louis

Fri 8/8

10:08 am-7:05 pm

2 stops25h 57m

$601

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/3

Showing 1-10 of 11 results
1
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Best time to book a flight from Missouri to Sicily

Have a flexible travel schedule? Discover the best time to fly to Sicily from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Sicily

What is the cheapest time of day to fly from MO to SI?

Find hourly flight availability from Missouri to Sicily. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

When flying from Missouri to Sicily, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Sicily

Get insights into the airlines that provide service to Sicily. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sicily. Reviews last updated July 3, 2025.
Read through reviews of airlines operating flights from Missouri to Sicily, such as Delta, KLM, and Air France. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Missouri to Sicily. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • Can I find deals for flights from Missouri to Sicily that include hotel bookings?

    Yes. In addition to deals on Missouri to Sicily flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Sicily?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Sicily.

  • Can I find deals for business class flights from Missouri to Sicily?

    Yes. Cheapflights offers flight deals from Missouri to Sicily by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Sicily?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Sicily (average of $667). Flying from Missouri to Sicily in June is currently the most expensive (average of $1,317). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Sicily

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Missouri to Sicily

Discover the top 2 airlines that operate flights from Missouri to Sicily. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$803Average$1,258FlexibilityNo cancel feeOn-time76%
DeltaCheapest$1,007Average$1,257FlexibilityNo cancel feeOn-timeN/A

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