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$241+ Cheap flights from Key Largo, FL to Sicily

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — CTA
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Key Largo to Sicily

Keep the following information in mind while searching for Key Largo to Sicily flight deals. Data was last updated September 16, 2025.

Round-trip from

$508
(lol.travel)

One-way from

$241
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$814
From Key Largo to Sicily
Search Deals
One-way flight from Key Largo to Sicily
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($114 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Key Largo to Sicily

Cheapest flights from Key Largo to Sicily
Explore the most affordable flight options available from Key Largo to Sicily. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This lol.travel deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/277:45 pmMIA - CTA
1 stop16h 00mMultiple Airlines
Mon 11/108:40 pmCTA - MIA
1 stop26h 50mMultiple Airlines
Deal found 9/14$508
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/202:25 pmMIA - PMO
2 stops18h 15mMultiple Airlines
Mon 11/311:45 pmPMO - MIA
2 stops23h 10mMultiple Airlines
Deal found 9/16$546
This Gotogate deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/207:30 pmMIA - PMO
1 stop34h 40mITA Airways
Mon 11/37:05 pmPMO - MIA
1 stop31h 50mITA Airways
Deal found 9/16$556
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/212:25 pmMIA - PMO
2 stops20h 30mMultiple Airlines
Tue 11/48:10 pmPMO - MIA
2 stops24h 30mMultiple Airlines
Deal found 9/15$558
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/212:25 pmMIA - PMO
2 stops20h 30mMultiple Airlines
Tue 10/2811:55 amPMO - MIA
2 stops35h 35mMultiple Airlines
Deal found 9/14$562
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/212:25 pmMIA - CTA
2 stops22h 20mMultiple Airlines
Tue 10/2811:40 amCTA - MIA
2 stops33h 00mMultiple Airlines
Deal found 9/14$565
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/217:30 pmMIA - PMO
1 stop21h 35mITA Airways
Tue 11/412:25 pmPMO - MIA
1 stop33h 50mITA Airways
Deal found 9/15$567
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/110:30 pmMIA - PMO
1 stop37h 15mTurkish Airlines
Fri 12/129:30 amPMO - MIA
1 stop17h 05mTurkish Airlines
Deal found 9/14$569
This lol.travel deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:40 pmMIA - CTA
2 stops18h 05mLufthansa
Mon 11/1012:15 pmCTA - MIA
2 stops34h 40mLufthansa
Deal found 9/15$574
This FlightHub deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:40 pmMIA - PMO
1 stop12h 50mITA Airways
Wed 11/196:10 amPMO - MIA
1 stop16h 05mITA Airways
Deal found 9/15$574
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2110:15 pmMIA - CTA
1 stop38h 00mTurkish Airlines
Tue 10/287:25 pmCTA - MIA
1 stop31h 10mTurkish Airlines
Deal found 9/14$578
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2812:15 amMIA - PMO
1 stop17h 45mITA Airways
Wed 11/56:10 amPMO - MIA
1 stop16h 05mITA Airways
Deal found 9/14$579

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to Sicily that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Key Largo to Sicily that are best for you.

Fly from

Key Largo

Fly to

Sicily

Route

Depart

Return

Price

MiamiCatania

MIA - CTA

MIACTA

Miami

Mon 10/27

7:45 pm-4:45 pm

1 stop16h 00m

Catania Fontanarossa

Mon 11/10

8:40 pm-5:30 pm

1 stop26h 50m

$508

MiamiPalermo

MIA - PMO

MIAPMO

Miami

Mon 10/20

2:25 pm-2:40 pm

2 stops18h 15m

Palermo Punta Raisi

Mon 11/3

11:45 pm-4:55 pm

2 stops23h 10m

$546

MiamiPalermo

MIA - PMO

MIAPMO

Miami

Mon 10/20

7:30 pm-12:10 pm

1 stop34h 40m

Palermo Punta Raisi

Mon 11/3

7:05 pm-8:55 pm

1 stop31h 50m

$556

MiamiCatania

MIA - CTA

MIACTA

Miami

Thu 2/12

10:30 pm-8:35 am

1 stop28h 05m

Catania Fontanarossa

Tue 2/17

7:25 pm-8:35 pm

1 stop31h 10m

$569

MiamiCatania

MIA - CTA

MIACTA

Miami

Tue 2/10

7:40 pm-9:30 am

1 stop31h 50m

Catania Fontanarossa

Tue 2/24

3:25 pm-4:15 pm

1 stop30h 50m

$574

MiamiCatania

MIA - CTA

MIACTA

Miami

Sat 11/1

12:15 am-11:10 pm

1 stop17h 55m

Catania Fontanarossa

Wed 11/12

6:00 am-4:15 pm

1 stop16h 15m

$574

MiamiPalermo

MIA - PMO

MIAPMO

Miami

Tue 2/10

7:40 pm-9:15 am

1 stop31h 35m

Palermo Punta Raisi

Tue 2/24

6:10 am-4:15 pm

1 stop16h 05m

$574

MiamiCatania

MIA - CTA

MIACTA

Miami

Mon 11/3

10:20 am-6:25 pm

1 stop26h 05m

Catania Fontanarossa

Thu 11/13

7:25 pm-8:35 pm

1 stop31h 10m

$578

MiamiPalermo

MIA - PMO

MIAPMO

Miami

Mon 11/10

4:40 pm-5:40 pm

2 stops19h 00m

Palermo Punta Raisi

Wed 11/19

7:10 am-10:29 pm

2 stops21h 19m

$586

MiamiPalermo

MIA - PMO

MIAPMO

Miami

Thu 10/23

4:30 pm-12:55 am

2 stops26h 25m

Palermo Punta Raisi

Sat 11/1

6:40 pm-11:05 pm

2 stops33h 25m

$592

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 40 results
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Best time to book a flight from Key Largo to Sicily

Have a flexible travel schedule? Discover the best time to fly to Sicily from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Sicily

What is the cheapest month to book a flight from Key Largo to Sicily?

Currently, January is the cheapest month in which you can book a flight from Key Largo to Sicily (average of $667). Flying from Key Largo to Sicily in June is currently the most expensive (average of $1,315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to SI?

Find hourly flight availability from Key Largo to Sicily. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Key Largo to Sicily, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Sicily

Get insights into the airlines that provide service to Sicily. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sicily. Reviews last updated September 16, 2025.
See what other customers who have flown with Delta, SWISS, and Turkish Airlines from Key Largo to Sicily have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
SWISS
7.6
Good
1,737 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Turkish Airlines
7.3
Good
3,968 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Iberia
7.0
Good
2,924 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
ITA Airways
6.7
Okay
1,036 reviews
Delta
8.0
Very good
7,957 reviews

Boarding

8.2

Comfort

7.9

Crew

8.5

Overall

8.0

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Sicily. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Key Largo to Sicily?

    For as low as $1,026, ITA Airways can have you in Sicily from Key Largo in 15h 55m. The distance between Key Largo and Sicily is about 5437 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Key Largo to Sicily?

    The most popular route from Key Largo to Sicily is Miami - Catania Fontanarossa. You may also consider Miami - Palermo Punta Raisi or Miami - Lamezia Terme Intl.

  • Can I find deals for flights from Key Largo to Sicily that include hotel bookings?

    Yes. In addition to deals on Key Largo to Sicily flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Sicily?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Sicily.

  • Can I find deals for business class flights from Key Largo to Sicily?

    Yes. Cheapflights offers flight deals from Key Largo to Sicily by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Sicily?

    Currently, January is the cheapest month in which you can book a flight from Key Largo to Sicily (average of $667). Flying from Key Largo to Sicily in June is currently the most expensive (average of $1,315). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Key Largo to Sicily

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Key Largo to Sicily

Discover the top 5 airlines that operate flights from Key Largo to Sicily. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$559Average$1,009FlexibilityNo cancel feeOn-timeN/A
IberiaCheapest$604Average$805FlexibilityNo cancel feeOn-time77%
Turkish AirlinesCheapest$626Average$713FlexibilityNo cancel feeOn-time77%
ITA AirwaysCheapest$657Average$977FlexibilityNo cancel feeOn-time81%
SWISSCheapest$675Average$1,058FlexibilityNo cancel feeOn-time79%

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