Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Odessa to Seville as you normally would.
For a flight from Odessa to Seville, you will be flying into Sevilla. Sevilla (SVQ) is just 5.6 mi from the center of the city. Sevilla is the only Seville airport and it handles 0 inbound flights from Odessa per day. 0 airlines have flights to Sevilla from Odessa on a regular basis.