Sao Paulo

$670+ Cheap flights from Iowa to Sao Paulo, Brazil (SAO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAO
Mar 14 — Mar 211
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Cheap flight deals from Iowa to Sao Paulo

Cheapest flights from Iowa to Sao Paulo
Explore the most affordable flight options available from Iowa to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:01 pm
OMA
-
GRU
1 stop32h 59m
Multiple Airlines
Sun 4/264:05 am
GRU
-
OMA
2 stops39h 06m
Multiple Airlines
Deal found 2/10$898
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:01 pm
OMA
-
GRU
1 stop32h 59m
Multiple Airlines
Thu 4/235:25 am
GRU
-
OMA
2 stops32h 19m
Multiple Airlines
Deal found 2/10$953
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:01 pm
OMA
-
GRU
1 stop32h 59m
Multiple Airlines
Sat 4/2512:50 pm
GRU
-
OMA
2 stops33h 24m
Multiple Airlines
Deal found 2/10$1,043
This Gurufare deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:30 pm
DSM
-
GRU
2 stops19h 45m
LATAM Airlines
Sat 9/269:30 pm
GRU
-
DSM
2 stops41h 52m
LATAM Airlines
Deal found 2/10$1,103
This KAYAK deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:49 am
DSM
-
GRU
2 stops19h 01m
LATAM Airlines
Tue 6/168:30 am
GRU
-
DSM
2 stops15h 56m
LATAM Airlines
Deal found 2/9$1,124
This KAYAK deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:30 am
OMA
-
GRU
1 stop22h 10m
LATAM Airlines
Thu 4/237:30 am
GRU
-
OMA
2 stops18h 40m
LATAM Airlines
Deal found 2/10$1,125
This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:05 am
OMA
-
GRU
2 stops19h 35m
LATAM Airlines
Sun 8/163:40 am
GRU
-
OMA
2 stops22h 19m
LATAM Airlines
Deal found 2/11$1,127
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:20 am
DSM
-
GRU
1 stop22h 10m
United Airlines
Tue 6/169:50 pm
GRU
-
DSM
1 stop18h 23m
United Airlines
Deal found 2/11$1,128
This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:21 pm
OMA
-
GRU
2 stops19h 49m
LATAM Airlines
Wed 6/1011:40 am
GRU
-
OMA
2 stops27h 58m
LATAM Airlines
Deal found 2/11$1,131
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
DSM
-
GRU
2 stops25h 30m
United Airlines
Tue 6/910:20 pm
GRU
-
DSM
1 stop14h 01m
United Airlines
Deal found 2/9$1,132
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:35 pm
OMA
-
GRU
2 stops19h 40m
Delta
Thu 4/237:30 am
GRU
-
OMA
2 stops18h 40m
Delta
Deal found 2/10$1,133
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:22 pm
OMA
-
GRU
2 stops35h 23m
United Airlines
Thu 4/239:50 pm
GRU
-
OMA
1 stop23h 16m
United Airlines
Deal found 2/10$1,137

Find flight deals from Iowa to Sao Paulo

Keep the following information in mind while searching for Iowa to Sao Paulo flight deals. Data was last updated February 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$898
(Kiwi.com)

One-way from

$670
(Copa Airlines)
Provider with most accurate pricing for Des Moines-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for Des Moines-Sao Paulo (SAO) flights.
From Iowa to Sao Paulo (SAO)
One-way flight from Iowa to Sao Paulo (SAO)

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Iowa to Sao Paulo that are best for you.

Fly from

Iowa

Fly to

Sao Paulo

Route

Depart

Return

Price

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Mon 4/13

6:01 pm-5:00 am

1 stop32h 59m

Sao Paulo Guarulhos Intl

Sat 4/25

12:50 pm-8:14 pm

2 stops33h 24m

$1,043

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Mon 4/13

7:04 am-5:40 am

1 stop20h 36m

Sao Paulo Guarulhos Intl

Thu 4/23

10:50 pm-10:43 am

1 stop13h 53m

$1,125

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Mon 4/13

7:04 am-5:40 am

1 stop20h 36m

Sao Paulo Guarulhos Intl

Mon 4/27

10:50 pm-10:43 am

1 stop13h 53m

$1,125

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Mon 4/13

6:35 pm-4:15 pm

2 stops19h 40m

Sao Paulo Guarulhos Intl

Thu 4/23

7:30 am-12:10 am

2 stops18h 40m

$1,133

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Mon 4/13

6:35 pm-4:15 pm

2 stops19h 40m

Sao Paulo Guarulhos Intl

Mon 4/27

7:10 am-12:10 am

2 stops19h 00m

$1,133

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Sun 4/12

5:22 pm-6:45 am

2 stops35h 23m

Sao Paulo Guarulhos Intl

Thu 4/23

9:50 pm-7:06 pm

1 stop23h 16m

$1,137

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Sun 4/12

5:22 pm-6:45 am

2 stops35h 23m

Sao Paulo Guarulhos Intl

Mon 4/27

9:50 pm-2:20 pm

2 stops18h 30m

$1,137

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Sun 4/12

6:09 pm-5:40 am

1 stop33h 31m

Sao Paulo Guarulhos Intl

Thu 4/23

10:50 pm-10:43 am

1 stop13h 53m

$1,144

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Sun 4/12

6:09 pm-5:40 am

1 stop33h 31m

Sao Paulo Guarulhos Intl

Mon 4/27

10:50 pm-10:43 am

1 stop13h 53m

$1,144

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Sat 4/11

12:00 pm-5:40 am

1 stop15h 40m

Sao Paulo Guarulhos Intl

Mon 4/27

10:50 pm-10:43 am

1 stop13h 53m

$1,165

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

Showing 1-10 of 21 results
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Best time to book a flight from Iowa to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Sao Paulo
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Iowa to Sao Paulo?

    Departing from Iowa to Sao Paulo will take you 19h 40m. The distance between Iowa and Sao Paulo is about 5474 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Iowa to Sao Paulo?

  • Can I find deals for flights from Iowa to Sao Paulo that include hotel bookings?

    Yes. In addition to deals on Iowa to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Sao Paulo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Sao Paulo.

  • Can I find deals for business class flights from Iowa to Sao Paulo?

    Yes. Cheapflights offers flight deals from Iowa to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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