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Sao Paulo

$415+ Cheap flights from Iowa to Sao Paulo, Brazil (SAO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAO
May 4 — May 111
Mon 5/4
Mon 5/11
1 adult, Economy
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Cheap flight deals from Iowa to Sao Paulo

Cheapest flights from Iowa to Sao Paulo
Explore the most affordable flight options available from Iowa to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/217:30 am
DSM
-
GRU
1 stop35h 10m
Multiple Airlines
Mon 7/62:20 am
GRU
-
DSM
2 stops40h 03m
Multiple Airlines
Deal found 3/30$1,024
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:07 am
OMA
-
GRU
1 stop16h 53m
Multiple Airlines
Sat 8/227:35 am
GRU
-
OMA
2 stops35h 31m
Multiple Airlines
Deal found 4/3$1,044
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/217:30 am
DSM
-
GRU
1 stop35h 10m
Multiple Airlines
Thu 7/92:20 am
GRU
-
DSM
2 stops21h 55m
Multiple Airlines
Deal found 3/30$1,048
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:06 pm
DSM
-
GRU
2 stops33h 14m
Multiple Airlines
Wed 7/88:30 am
GRU
-
DSM
1 stop26h 03m
Multiple Airlines
Deal found 4/1$1,056
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:06 pm
DSM
-
GRU
2 stops33h 14m
Multiple Airlines
Wed 7/88:30 am
GRU
-
DSM
1 stop26h 03m
Multiple Airlines
Deal found 3/30$1,065
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:06 pm
DSM
-
GRU
2 stops33h 14m
Multiple Airlines
Mon 7/611:40 am
GRU
-
DSM
1 stop29h 44m
Multiple Airlines
Deal found 4/1$1,090
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/217:30 am
DSM
-
GRU
1 stop35h 10m
Multiple Airlines
Wed 7/85:15 pm
GRU
-
DSM
2 stops48h 35m
Multiple Airlines
Deal found 3/30$1,103
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/217:30 am
DSM
-
GRU
1 stop35h 10m
Multiple Airlines
Sun 7/52:20 am
GRU
-
DSM
2 stops21h 55m
Multiple Airlines
Deal found 3/30$1,110
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/287:30 am
DSM
-
GRU
1 stop35h 10m
Multiple Airlines
Mon 7/62:20 am
GRU
-
DSM
2 stops40h 03m
Multiple Airlines
Deal found 3/30$1,126
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:00 am
DSM
-
GRU
1 stop35h 40m
Multiple Airlines
Thu 5/2111:50 am
GRU
-
DSM
2 stops28h 10m
Multiple Airlines
Deal found 3/30$1,127
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/289:27 am
DSM
-
GRU
2 stops16h 53m
Multiple Airlines
Wed 7/88:30 am
GRU
-
DSM
1 stop26h 03m
Multiple Airlines
Deal found 3/30$1,129
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:06 pm
DSM
-
GRU
2 stops33h 14m
Multiple Airlines
Mon 7/611:40 am
GRU
-
DSM
1 stop29h 44m
Multiple Airlines
Deal found 3/30$1,130

Find flight deals from Iowa to Sao Paulo

Keep the following information in mind while searching for Iowa to Sao Paulo flight deals. Data was last updated April 4, 2026.

Round-trip from

$1,024
(Kiwi.com)

One-way from

$415
(Kiwi.com)
From Iowa to Sao Paulo (SAO)
Search Deals
One-way flight from Iowa to Sao Paulo (SAO)
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2026.
Use the filters below to find and compare flights from Iowa to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 5/14

7:00 am-8:40 pm

1 stop35h 40m

Sao Paulo Guarulhos Intl

Thu 5/21

11:50 am-2:00 pm

2 stops28h 10m

$1,127

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 9/13

6:30 pm-8:00 pm

2 stops23h 30m

Sao Paulo Guarulhos Intl

Sun 9/20

11:45 pm-5:42 pm

2 stops19h 57m

$1,159

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 6/23

4:11 pm-5:25 am

2 stops35h 14m

Sao Paulo Guarulhos Intl

Wed 7/8

8:30 am-8:33 am

1 stop26h 03m

$1,173

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Thu 8/13

6:25 pm-9:40 am

1 stop13h 15m

Sao Paulo Guarulhos Intl

Sun 8/23

10:20 pm-2:14 pm

1 stop17h 54m

$1,213

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Fri 8/14

5:35 am-5:30 am

2 stops21h 55m

Sao Paulo Guarulhos Intl

Sun 8/23

11:45 pm-9:13 pm

2 stops23h 28m

$1,213

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Wed 5/27

6:25 pm-9:40 am

1 stop13h 15m

Sao Paulo Guarulhos Intl

Wed 6/10

10:20 pm-2:17 pm

1 stop17h 57m

$1,213

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Wed 5/27

6:29 pm-4:15 pm

2 stops19h 46m

Sao Paulo Guarulhos Intl

Fri 6/12

7:30 am-11:50 pm

2 stops18h 20m

$1,235

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 6/28

8:30 pm-9:40 am

1 stop35h 10m

Sao Paulo Guarulhos Intl

Tue 7/7

9:50 pm-10:35 pm

1 stop26h 45m

$1,247

OmahaSao Paulo

OMA - GRU

OMAGRU

Omaha Eppley Airfield

Wed 5/27

6:25 pm-9:40 am

1 stop13h 15m

Sao Paulo Guarulhos Intl

Fri 6/12

10:20 pm-10:27 am

1 stop14h 07m

$1,253

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 6/28

8:30 pm-9:40 am

1 stop35h 10m

Sao Paulo Guarulhos Intl

Fri 7/10

10:20 pm-9:40 pm

1 stop25h 20m

$1,283

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 25 resultsSorted by cheapest first
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Best time to book a flight from Iowa to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Sao Paulo
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Sao Paulo?

    Departing from Iowa to Sao Paulo will take you 23h 30m. The distance between Iowa and Sao Paulo is about 5405 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Iowa to Sao Paulo?

    While some choose either Des Moines - Sao Paulo Guarulhos Intl or Moline Quad-City - Sao Paulo Guarulhos Intl, Omaha Eppley Airfield - Sao Paulo Guarulhos Intl is the most popular route from Iowa to Sao Paulo.

  • Can I find deals for flights from Iowa to Sao Paulo that include hotel bookings?

    Yes. In addition to deals on Iowa to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Sao Paulo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Sao Paulo.

  • Can I find deals for business class flights from Iowa to Sao Paulo?

    Yes. Cheapflights offers flight deals from Iowa to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
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