$123+ Cheap flights from Iowa to San Antonio (SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAT
Aug 28 — Sep 41
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Iowa to San Antonio
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Cheapest flights from Iowa to San AntonioExplore the most affordable flight options available from Iowa to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
Explore the most affordable flight options available from Iowa to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
This CheapOair deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:41 pm
OMA
- SAT
1 stop14h 40m
Frontier
Sat 10/1712:16 pm
SAT
- OMA
1 stop7h 30m
Frontier
Deal found 7/27![Frontier logo]()
$251
This CheapOair deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:41 pm
OMA
- SAT
1 stop13h 31m
Frontier
Mon 11/211:08 am
SAT
- OMA
1 stop8h 38m
Frontier
Deal found 7/28![Frontier logo]()
$256
This CheapOair deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:29 pm
OMA
- SAT
1 stop23h 56m
Frontier
Tue 9/158:20 pm
SAT
- OMA
1 stop22h 14m
Frontier
Deal found 7/25![Frontier logo]()
$257
This Frontier deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:24 pm
CID
- SAT
1 stop22h 30m
Frontier
Sat 8/228:26 pm
SAT
- CID
1 stop17h 17m
Frontier
Deal found 7/24![Frontier logo]()
$260
This CheapOair deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:18 pm
OMA
- SAT
1 stop5h 13m
Frontier
Sun 8/308:26 pm
SAT
- OMA
1 stop17h 07m
Frontier
Deal found 7/27![Frontier logo]()
$261
This CheapOair deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:29 am
DSM
- SAT
1 stop7h 56m
Frontier
Thu 10/83:10 pm
SAT
- DSM
1 stop22h 08m
Frontier
Deal found 7/25![Frontier logo]()
$265
This Frontier deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:00 pm
OMA
- SAT
1 stop23h 31m
Frontier
Wed 8/268:26 pm
SAT
- OMA
1 stop17h 07m
Frontier
Deal found 7/28![Frontier logo]()
$271
This CheapOair deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:00 pm
OMA
- SAT
1 stop22h 54m
Frontier
Wed 8/198:26 pm
SAT
- OMA
1 stop17h 07m
Frontier
Deal found 7/27![Frontier logo]()
$281
This CheapOair deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:15 pm
OMA
- SAT
1 stop22h 39m
Frontier
Thu 8/137:49 pm
SAT
- OMA
1 stop23h 26m
Frontier
Deal found 7/27![Frontier logo]()
$291
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:44 pm
MLI
- SAT
1 stop7h 06m
United Airlines
Tue 9/11:45 pm
SAT
- MLI
1 stop7h 16m
United Airlines
Deal found 7/24![United Airlines logo]()
$293
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/152:55 pm
OMA
- SAT
1 stop4h 28m
United Airlines
Tue 12/294:18 pm
SAT
- OMA
1 stop5h 57m
United Airlines
Deal found 7/27![United Airlines logo]()
$294
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/165:39 pm
OMA
- SAT
1 stop6h 52m
Delta
Mon 12/216:15 pm
SAT
- OMA
1 stop5h 52m
Delta
Deal found 7/27![Delta logo]()
$299
Best flights from Iowa to San AntonioDiscover carefully curated flight deals from Iowa to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
Discover carefully curated flight deals from Iowa to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:44 pm
MLI
- SAT
1 stop7h 06m
United Airlines
Tue 9/11:45 pm
SAT
- MLI
1 stop7h 16m
United Airlines
Deal found 7/24![United Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:20 pm
OMA
- SAT
2 stops6h 40m
Southwest
Mon 9/146:40 am
SAT
- OMA
1 stop5h 50m
Southwest
Deal found 7/26![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:19 am
MLI
- SAT
1 stop7h 44m
Delta
Wed 9/165:15 am
SAT
- MLI
2 stops11h 14m
Delta
Deal found 7/25![Delta logo]()
$318
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:32 pm
MLI
- SAT
1 stop6h 18m
American Airlines
Sun 9/610:59 am
SAT
- MLI
2 stops7h 20m
American Airlines
Deal found 7/28![American Airlines logo]()
$321
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:07 am
OMA
- SAT
1 stop7h 48m
United Airlines
Mon 9/145:30 am
SAT
- OMA
1 stop5h 13m
United Airlines
Deal found 7/26![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/163:05 pm
OMA
- SAT
2 stops6h 30m
Southwest
Sat 9/191:10 pm
SAT
- OMA
1 stop6h 35m
Southwest
Deal found 7/25![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/911:08 am
MLI
- SAT
2 stops10h 02m
Delta
Wed 10/144:29 pm
SAT
- MLI
1 stop6h 01m
Delta
Deal found 7/28![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:05 pm
OMA
- SAT
2 stops8h 05m
Southwest
Wed 9/167:45 am
SAT
- OMA
1 stop8h 05m
Southwest
Deal found 7/24![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:43 pm
DSM
- SAT
1 stop6h 43m
Delta
Wed 11/182:33 pm
SAT
- DSM
1 stop4h 42m
Delta
Deal found 7/28![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:00 am
DSM
- SAT
1 stop7h 38m
United Airlines
Tue 11/174:19 pm
SAT
- DSM
1 stop6h 11m
United Airlines
Deal found 7/26![United Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:27 am
DSM
- SAT
2 stops7h 35m
American Airlines
Wed 11/182:55 pm
SAT
- DSM
1 stop3h 59m
American Airlines
Deal found 7/28![American Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:25 am
OMA
- SAT
1 stop4h 55m
Southwest
Thu 9/176:00 am
SAT
- OMA
1 stop4h 25m
Southwest
Deal found 7/25![Southwest logo]()
$304
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2310:30 am
MLI
- SAT
1 stop6h 01m
United Airlines
Sun 8/305:30 pm
SAT
- MLI
1 stop5h 44m
United Airlines
Deal found 7/27![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:16 pm
CID
- SAT
2 stops8h 12m
Delta
Mon 8/242:43 pm
SAT
- CID
1 stop7h 40m
Delta
Deal found 7/25![Delta logo]()
$334
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:05 am
OMA
- SAT
1 stop6h 25m
Southwest
Tue 9/154:20 pm
SAT
- OMA
2 stops5h 50m
Southwest
Deal found 7/25![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:05 am
CID
- SAT
1 stop7h 50m
United Airlines
Tue 9/151:45 pm
SAT
- CID
1 stop7h 08m
United Airlines
Deal found 7/26![United Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:50 pm
LSE
- SAT
1 stop5h 08m
American Airlines
Mon 10/266:38 pm
SAT
- LSE
1 stop5h 21m
American Airlines
Deal found 7/26![American Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/91:45 pm
OMA
- SAT
1 stop6h 03m
Delta
Wed 10/142:30 pm
SAT
- OMA
1 stop4h 53m
Delta
Deal found 7/28![Delta logo]()
$335
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:05 am
CID
- SAT
1 stop7h 50m
United Airlines
Sun 9/135:30 pm
SAT
- CID
1 stop5h 12m
United Airlines
Deal found 7/24![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:05 am
DSM
- SAT
1 stop6h 55m
Southwest
Tue 11/171:00 pm
SAT
- DSM
2 stops7h 45m
Southwest
Deal found 7/26![Southwest logo]()
$330
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/711:00 am
CID
- SAT
2 stops11h 27m
Delta
Sun 1/105:30 am
SAT
- CID
2 stops10h 22m
Delta
Deal found 7/25![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2212:24 pm
LSE
- SAT
2 stops10h 30m
American Airlines
Sat 8/296:00 am
SAT
- LSE
2 stops8h 42m
American Airlines
Deal found 7/25![American Airlines logo]()
$424
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:10 am
DSM
- SAT
2 stops7h 40m
Southwest
Thu 12/32:40 pm
SAT
- DSM
1 stop7h 25m
Southwest
Deal found 7/26![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:15 pm
MLI
- SAT
2 stops8h 01m
United Airlines
Sat 8/222:15 pm
SAT
- MLI
2 stops8h 59m
United Airlines
Deal found 7/24![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:50 am
CID
- SAT
1 stop4h 59m
Delta
Sat 8/226:30 am
SAT
- CID
1 stop4h 50m
Delta
Deal found 7/28![Delta logo]()
$354
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:26 pm
LSE
- SAT
1 stop5h 43m
American Airlines
Sun 9/276:48 pm
SAT
- LSE
1 stop5h 32m
American Airlines
Deal found 7/24![American Airlines logo]()
$430
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am
DSM
- SAT
2 stops8h 00m
Southwest
Thu 11/269:15 am
SAT
- DSM
2 stops8h 00m
Southwest
Deal found 7/26![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:42 am
MLI
- SAT
2 stops7h 01m
United Airlines
Wed 9/1612:00 pm
SAT
- MLI
2 stops9h 00m
United Airlines
Deal found 7/25![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:20 pm
LSE
- SAT
1 stop7h 28m
American Airlines
Sat 8/155:59 am
SAT
- LSE
1 stop5h 55m
American Airlines
Deal found 7/27![American Airlines logo]()
$446
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:29 pm
CID
- SAT
2 stops11h 59m
Delta
Sat 8/152:43 pm
SAT
- CID
1 stop7h 40m
Delta
Deal found 7/28![Delta logo]()
$384
Last-minute flights from Iowa to San AntonioDiscover last-minute flight deals from Iowa to San Antonio. Data last updated July 29, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to San Antonio. Data last updated July 29, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:00 pm
OMA
- SAT
1 stop22h 54m
Frontier
Tue 8/117:49 pm
SAT
- OMA
1 stop23h 26m
Frontier
Deal found 7/26![Frontier logo]()
$322
This CheapOair deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:15 pm
OMA
- SAT
1 stop22h 39m
Frontier
Thu 8/137:49 pm
SAT
- OMA
1 stop23h 26m
Frontier
Deal found 7/27![Frontier logo]()
$291
This Frontier deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:24 pm
CID
- SAT
1 stop22h 30m
Frontier
Sat 8/228:26 pm
SAT
- CID
1 stop17h 17m
Frontier
Deal found 7/24![Frontier logo]()
$260
This CheapOair deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:00 pm
OMA
- SAT
1 stop22h 54m
Frontier
Wed 8/198:26 pm
SAT
- OMA
1 stop17h 07m
Frontier
Deal found 7/27![Frontier logo]()
$281
This Frontier deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:00 pm
OMA
- SAT
1 stop23h 31m
Frontier
Wed 8/268:26 pm
SAT
- OMA
1 stop17h 07m
Frontier
Deal found 7/28![Frontier logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1712:06 pm
OMA
- SAT
2 stops31h 25m
Multiple Airlines
Wed 8/268:26 pm
SAT
- OMA
1 stop17h 07m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$302
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:33 am
DSM
- SAT
1 stop5h 16m
American Airlines
Wed 8/268:00 am
SAT
- DSM
1 stop7h 12m
American Airlines
Deal found 7/26![American Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:45 pm
MLI
- SAT
1 stop5h 55m
American Airlines
Sun 8/235:00 am
SAT
- MLI
1 stop6h 02m
American Airlines
Deal found 7/27![American Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:44 pm
MLI
- SAT
1 stop7h 06m
United Airlines
Tue 9/11:45 pm
SAT
- MLI
1 stop7h 16m
United Airlines
Deal found 7/24![United Airlines logo]()
$293
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/254:32 pm
MLI
- SAT
1 stop5h 28m
American Airlines
Wed 9/26:52 pm
SAT
- MLI
1 stop5h 16m
American Airlines
Deal found 7/27![American Airlines logo]()
$316
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:14 am
MLI
- SAT
2 stops7h 29m
United Airlines
Wed 9/212:55 pm
SAT
- MLI
1 stop6h 36m
United Airlines
Deal found 7/27![United Airlines logo]()
$321
This CheapOair deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:18 pm
OMA
- SAT
1 stop5h 13m
Frontier
Sun 8/308:26 pm
SAT
- OMA
1 stop17h 07m
Frontier
Deal found 7/27![Frontier logo]()
$261
One-way flights from Iowa to San AntonioSearch for one-way flight options from Iowa to San Antonio. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
Search for one-way flight options from Iowa to San Antonio. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
This Orbitz deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am
DSM
- SAT
1 stop7h 56m
Frontier
Deal found 7/26![Frontier logo]()
$123
This Priceline deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:19 pm
DSM
- SAT
1 stop5h 12m
Frontier
Deal found 7/24![Frontier logo]()
$131
This CheapOair deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:31 pm
DSM
- SAT
1 stop20h 50m
Frontier
Deal found 7/27![Frontier logo]()
$134
This CheapOair deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:30 pm
DSM
- SAT
1 stop22h 55m
Frontier
Deal found 7/25![Frontier logo]()
$135
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/161:45 pm
OMA
- SAT
1 stop7h 22m
United Airlines
Deal found 7/27![United Airlines logo]()
$150
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/165:45 am
OMA
- SAT
2 stops7h 35m
Southwest
Deal found 7/27![Southwest logo]()
$155
This Trip.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:15 pm
OMA
- SAT
1 stop22h 39m
Frontier
Deal found 7/28![Frontier logo]()
$159
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:00 am
DSM
- SAT
1 stop5h 52m
United Airlines
Deal found 7/24![United Airlines logo]()
$163
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:50 am
CID
- SAT
1 stop6h 28m
American Airlines
Deal found 7/24![American Airlines logo]()
$167
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:25 pm
DSM
- SAT
2 stops7h 35m
Southwest
Deal found 7/27![Southwest logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:12 pm
CID
- SAT
1 stop23h 34m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$168
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:55 am
CID
- SAT
2 stops7h 48m
United Airlines
Deal found 7/24![United Airlines logo]()
$172
Find flight deals from Iowa to San Antonio
Keep the following information in mind while searching for Iowa to San Antonio flight deals. Data was last updated July 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $251 (CheapOair) |
One-way from | $123 (Orbitz) |
Popular in | June |
Cheapest in | August |
Average price | $406 |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Iowa to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MolineSan Antonio
MLI - SAT
MLISAT
Moline Quad-City
Tue 8/25
3:44 pm-10:50 pm
1 stop7h 06m
San Antonio
Tue 9/1
1:45 pm-9:01 pm
1 stop7h 16m
$293
OmahaSan Antonio
OMA - SAT
OMASAT
Omaha Eppley Airfield
Thu 9/10
9:07 am-4:55 pm
1 stop7h 48m
San Antonio
Mon 9/14
5:30 am-10:43 am
1 stop5h 13m
$299
OmahaSan Antonio
OMA - SAT
OMASAT
Omaha Eppley Airfield
Thu 9/10
3:20 pm-10:00 pm
2 stops6h 40m
San Antonio
Mon 9/14
6:40 am-12:30 pm
1 stop5h 50m
$304
OmahaSan Antonio
OMA - SAT
OMASAT
Omaha Eppley Airfield
Wed 9/16
3:05 pm-9:35 pm
2 stops6h 30m
San Antonio
Sat 9/19
1:10 pm-7:45 pm
1 stop6h 35m
$304
OmahaSan Antonio
OMA - SAT
OMASAT
Omaha Eppley Airfield
Tue 9/15
3:05 pm-11:10 pm
2 stops8h 05m
San Antonio
Wed 9/16
7:45 am-3:50 pm
1 stop8h 05m
$304
Quickest round-trip
OmahaSan Antonio
OMA - SAT
OMASAT
Omaha Eppley Airfield
Fri 9/11
10:25 am-3:20 pm
1 stop4h 55m
San Antonio
Thu 9/17
6:00 am-10:25 am
1 stop4h 25m
$304
OmahaSan Antonio
OMA - SAT
OMASAT
Omaha Eppley Airfield
Fri 9/11
7:05 am-1:30 pm
1 stop6h 25m
San Antonio
Tue 9/15
4:20 pm-10:10 pm
2 stops5h 50m
$309
MolineSan Antonio
MLI - SAT
MLISAT
Moline Quad-City
Wed 9/9
11:19 am-7:03 pm
1 stop7h 44m
San Antonio
Wed 9/16
5:15 am-4:29 pm
2 stops11h 14m
$318
MolineSan Antonio
MLI - SAT
MLISAT
Moline Quad-City
Tue 9/1
4:32 pm-10:50 pm
1 stop6h 18m
San Antonio
Sun 9/6
10:59 am-6:19 pm
2 stops7h 20m
$321
MolineSan Antonio
MLI - SAT
MLISAT
Moline Quad-City
Fri 10/9
11:08 am-9:10 pm
2 stops10h 02m
San Antonio
Wed 10/14
4:29 pm-10:30 pm
1 stop6h 01m
$321
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Iowa with our price prediction graph.
DSM-SAT
OMA-SAT
CID-SAT
MLI-SAT
LSE-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to San Antonio
USIA-SAT
DSM-SAT
OMA-SAT
CID-SAT
MLI-SAT
What is the cheapest month to book a flight from Iowa to San Antonio?
Currently, January is the cheapest month in which you can book a flight from Iowa to San Antonio (average of $315). Flying from Iowa to San Antonio in June is currently the most expensive (average of $573). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Iowa to San Antonio?
Airfare is typical for this route at the moment.
Iowa to San Antonio flights typically cost between $246 and $362 in October.The cheapest round-trip price found within the last 5 days was $265 on Frontier (Oct 4-Oct 8).
How far ahead should I book a flight from Iowa to San Antonio?
The price you pay for your flight from Iowa to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 50 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from Iowa to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Iowa to San Antonio
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Complete your trip
Complete your trip to San Antonio by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to San Antonio by cabin class
Find flights from Iowa to San Antonio, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and San Antonio flights
Browse other Iowa and San Antonio flight options. Last updated on July 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Antonio
Explore flights to San Antonio departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 29, 2026.
Iowa to San Antonio flights
Consider these flights traveling from Iowa to San Antonio.
Top 4 airlines flying from Iowa to San Antonio
Discover the top 4 airlines that operate flights from Iowa to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$213 | Average$356 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$221 | Average$381 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$387 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$359 | Average$421 | FlexibilityNo cancel fee | On-time63% |