What are the cheapest airlines flying from Des Moines to Sao Paulo round-trip?

Flying on Delta is currently your cheapest option to Sao Paulo, with prices starting at $1,039. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $1,090 and $1,103, respectively. Delta is currently priced 10% below the average price you’ll pay for this route.

What is the cheapest month to book a flight from Des Moines to Sao Paulo?

Currently, April is the cheapest month in which you can book a flight from Des Moines to Sao Paulo (average of $686). Flying from Des Moines to Sao Paulo in December is currently the most expensive (average of $1,209). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest day to fly from Des Moines to Sao Paulo?

Travelers seeking maximum savings on their Des Moines to Sao Paulo flight should consider departing on Sunday afternoons when fares are most often at their lowest. Wednesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What is the cheapest day to fly round-trip from Des Moines to Sao Paulo?

Departing on a Monday is a good option for securing a great price. You can expect to save up to 7% when planning your travel around this day of the week.

What is the cheapest month to fly from Des Moines to Sao Paulo?

Flights from Des Moines to Sao Paulo lean towards being more expensive in June. Prices are generally better when you fly from Des Moines to Sao Paulo in April, with the cheapest ticket starting at $706.

What is the cheapest time of day to fly from DSM to SAO?

It’s optimal to fly from Des Moines to Sao Paulo at noon. By choosing this option you can save up to 8% on the cost of your flight, compared to a flight in the morning.

Most accurate provider : When it comes to deals on Des Moines-Sao Paulo flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Des Moines-Sao Paulo flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Des Moines-Sao Paulo flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Sao Paulo flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Sao Paulo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airport do you fly from for flights from Des Moines to Sao Paulo?

Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Sao Paulo from Des Moines. Booking flights from Des Moines (DSM) to Sao Paulo should be relatively easy as there are 0 daily outbound flights to Sao Paulo from 1 airline.

Can I find deals for flights from Des Moines to Sao Paulo that include hotel bookings?

Yes. In addition to deals on Des Moines to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Sao Paulo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Sao Paulo.

Can I find deals for business class flights from Des Moines to Sao Paulo?

Yes. Cheapflights offers flight deals from Des Moines to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$773+ Flights from Des Moines to Sao Paulo, Brazil

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1. Tell us where you want to go

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Cheap flight deals from Des Moines to Sao Paulo

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$773 (Mytrip)
Popular in	June
Cheapest in	April
Average price	$862

Provider with most accurate pricing for Des Moines-Sao Paulo (SAO) flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Sao Paulo (SAO) flights.

Search Deals

From Des Moines to Sao Paulo (SAO)

Search Deals

Highest demand for flights based on searches. 18% potential increase in price ($266 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 10% potential price decrease ($111 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Find flight deals from Des Moines to Sao Paulo

Cheapest flights from Des Moines to Sao Paulo
Explore the most affordable flight options available from Des Moines to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

Thu 6/123:48 pmDSM - GRU

3 stops45h 32mMultiple Airlines

Thu 6/195:25 amGRU - DSM

2 stops33h 21mMultiple Airlines

Deal found 4/28

$773

Mon 9/811:04 amDSM - GRU

1 stop16h 36mDelta

Mon 9/2210:05 amGRU - DSM

1 stop14h 18mDelta

Deal found 4/28

$1,039

Wed 7/303:38 pmDSM - GRU

2 stops15h 52mUnited Airlines

Wed 8/209:30 pmGRU - DSM

2 stops21h 44mUnited Airlines

Deal found 4/28

$1,090

Thu 5/292:20 pmDSM - GRU

2 stops16h 40mAmerican Airlines

Mon 6/911:15 pmGRU - DSM

2 stops17h 55mAmerican Airlines

Deal found 4/28

$1,103

Mon 9/82:14 pmDSM - GRU

1 stop13h 26mLATAM Airlines

Sun 9/213:40 amGRU - DSM

2 stops32h 38mLATAM Airlines

Deal found 4/29

$1,104

Thu 5/298:00 amDSM - GRU

2 stops19h 35mAvianca

Sun 6/81:45 amGRU - DSM

2 stops21h 37mAvianca

Deal found 4/28

$1,342

Best flights from Des Moines to Sao Paulo
Discover carefully curated flight deals from Des Moines to Sao Paulo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2025.

Thu 6/123:48 pmDSM - GRU

3 stops45h 32mMultiple Airlines

Thu 6/195:25 amGRU - DSM

2 stops33h 21mMultiple Airlines

Deal found 4/28

$773

Mon 9/811:04 amDSM - GRU

1 stop16h 36mDelta

Mon 9/2210:05 amGRU - DSM

1 stop14h 18mDelta

Deal found 4/28

$1,039

Wed 7/303:38 pmDSM - GRU

1 stop15h 52mUnited Airlines

Wed 8/209:50 pmGRU - DSM

1 stop18h 27mUnited Airlines

Deal found 4/28

$1,090

Thu 5/292:20 pmDSM - GRU

2 stops16h 40mAmerican Airlines

Mon 6/911:15 pmGRU - DSM

2 stops17h 55mAmerican Airlines

Deal found 4/28

$1,103

Mon 9/82:14 pmDSM - GRU

1 stop13h 26mLATAM Airlines

Sun 9/213:40 amGRU - DSM

2 stops32h 38mLATAM Airlines

Deal found 4/29

$1,104

Thu 5/298:00 amDSM - GRU

2 stops19h 35mAvianca

Sun 6/81:45 amGRU - DSM

2 stops21h 37mAvianca

Deal found 4/28

$1,342

Last-minute flights from Des Moines to Sao Paulo
Discover last-minute flight deals from Des Moines to Sao Paulo. Data last updated April 29, 2025 and is based on user searches.

Sat 5/38:07 amDSM - GRU

1 stop23h 23mUnited Airlines

Mon 5/510:20 pmGRU - DSM

1 stop18h 18mUnited Airlines

Deal found 4/29

$1,239

Sat 5/35:45 amDSM - GRU

1 stop21h 55mMultiple Airlines

Sun 5/41:30 amGRU - DSM

2 stops18h 20mMultiple Airlines

Deal found 4/29

$1,423

Sat 5/35:22 pmDSM - GRU

3 stops19h 58mLATAM Airlines

Mon 5/54:10 pmGRU - DSM

2 stops20h 31mLATAM Airlines

Deal found 4/29

$2,879

Thu 5/292:15 pmDSM - GRU

1 stop13h 25mDelta

Mon 6/94:10 pmGRU - DSM

2 stops20h 29mDelta

Deal found 4/28

$1,099

Thu 5/292:20 pmDSM - GRU

2 stops16h 40mAmerican Airlines

Mon 6/911:15 pmGRU - DSM

2 stops17h 55mAmerican Airlines

Deal found 4/28

$1,103

Thu 5/298:00 amDSM - GRU

2 stops19h 35mAvianca

Sun 6/81:45 amGRU - DSM

2 stops21h 37mAvianca

Deal found 4/28

$1,342

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 6/12

3:48 pm-3:20 pm

3 stops45h 32m

Sao Paulo Guarulhos Intl

Thu 6/19

5:25 am-12:46 pm

2 stops33h 21m

$773

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 9/8

11:04 am-5:40 am

1 stop16h 36m

Sao Paulo Guarulhos Intl

Mon 9/22

10:05 am-10:23 pm

1 stop14h 18m

$1,039

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 7/30

3:38 pm-9:30 am

2 stops15h 52m

Sao Paulo Guarulhos Intl

Wed 8/20

9:30 pm-5:14 pm

2 stops21h 44m

$1,090

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 5/29

2:20 pm-9:00 am

2 stops16h 40m

Sao Paulo Guarulhos Intl

Mon 6/9

11:15 pm-3:10 pm

2 stops17h 55m

$1,103

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 9/8

2:14 pm-5:40 am

1 stop13h 26m

Sao Paulo Guarulhos Intl

Sun 9/21

3:40 am-10:18 am

2 stops32h 38m

$1,104

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 5/29

8:00 am-5:35 am

2 stops19h 35m

Sao Paulo Guarulhos Intl

Sun 6/8

1:45 am-9:22 pm

2 stops21h 37m

$1,342

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Compare providers for flights from Des Moines to Sao Paulo

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Sao Paulo in April.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Sao Paulo flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Des Moines-Sao Paulo flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Des Moines-Sao Paulo flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Sao Paulo flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Sao Paulo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Sao Paulo

Rainfall in Sao Paulo by month

In terms of precipitation, rainfall in Sao Paulo ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit Sao Paulo when rainfall is around 0.8 in.

Temperature in Sao Paulo by month

If weather is an important factor for your trip to Sao Paulo, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing Sao Paulo

Delta

8.0

Very good

7,936 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,936 reviews

Delta

8.0

Very good

7,936 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines

7.5

Good

1,767 reviews

Delta

8.0

Very good

7,936 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,696 reviews

Delta

8.0

Very good

7,936 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,936 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Avianca

6.7

Okay

2,317 reviews

Delta

8.0

Very good

7,936 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airport do you fly from for flights from Des Moines to Sao Paulo?
Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Sao Paulo from Des Moines. Booking flights from Des Moines (DSM) to Sao Paulo should be relatively easy as there are 0 daily outbound flights to Sao Paulo from 1 airline.
What are the cheapest airlines flying from Des Moines to Sao Paulo round-trip?
Flying on Delta is currently your cheapest option to Sao Paulo, with prices starting at $1,039. Additional round-trip tickets that might be worth considering are offered by United Airlines and American Airlines, with the lowest prices starting at $1,090 and $1,103, respectively. Delta is currently priced 10% below the average price you’ll pay for this route.
Can I find deals for flights from Des Moines to Sao Paulo that include hotel bookings?
Yes. In addition to deals on Des Moines to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Sao Paulo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Sao Paulo.
Can I find deals for business class flights from Des Moines to Sao Paulo?
Yes. Cheapflights offers flight deals from Des Moines to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Sao Paulo?
Currently, April is the cheapest month in which you can book a flight from Des Moines to Sao Paulo (average of $686). Flying from Des Moines to Sao Paulo in December is currently the most expensive (average of $1,209). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Santos

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Top airline flying from Des Moines to Sao Paulo

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$677	Average$853	FlexibilityNo cancel fee	On-timeN/A

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$773+ Cheap flights from Des Moines (DSM) to Sao Paulo, Brazil (SAO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Sao Paulo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to Sao Paulo

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from Des Moines to Sao Paulo

Cheapest flights from Des Moines to Sao PauloExplore the most affordable flight options available from Des Moines to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

Explore the most affordable flight options available from Des Moines to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Sao Paulo that are best for you.

Compare providers for flights from Des Moines to Sao Paulo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Sao Paulo in April.

Best time to book a flight from Des Moines to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Sao Paulo

Rainfall in Sao Paulo by month

Plan your trip to Sao Paulo by taking into account the average rainfall totals by month.

Temperature in Sao Paulo by month

Plan your trip to Sao Paulo by taking into account the average temperature totals by month.

Reviews of airlines servicing Sao Paulo

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to Sao Paulo?

What are the cheapest airlines flying from Des Moines to Sao Paulo round-trip?

Can I find deals for flights from Des Moines to Sao Paulo that include hotel bookings?

How can I find direct flights from Des Moines to Sao Paulo?

Can I find deals for business class flights from Des Moines to Sao Paulo?

What is the cheapest month to book a flight from Des Moines to Sao Paulo?

Traveling to a place near Des Moines?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Des Moines to Sao Paulo

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Des Moines to Sao Paulo

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Book with Flexibility

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Cheapest flights from Des Moines to Sao Paulo
Explore the most affordable flight options available from Des Moines to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.