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$373+ Cheap flights from Des Moines (DSM) to Sao Paulo, Brazil (SAO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAO
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Des Moines to Sao Paulo

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Sao Paulo (SAO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated junio 12, 2025.

Round-trip from

$1,011
(Mytrip)

One-way from

$457
(Mytrip)

Popular in

June

Cheapest in

April

Average price

$2,165
From Des Moines to Sao Paulo (SAO)
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One-way flight from Des Moines to Sao Paulo (SAO)
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Highest demand for flights based on searches. 19% potential increase in price ($276 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($110 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Des Moines to Sao Paulo

Cheapest flights from Des Moines to Sao Paulo
Explore the most affordable flight options available from Des Moines to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/256:30 amDSM - GRU
3 stops36h 40mMultiple Airlines
vie. 8/19:40 pmGRU - DSM
2 stops21h 36mMultiple Airlines
Deal found 6/10$1,011
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/1511:04 amDSM - GRU
2 stops17h 11mDelta
lun. 9/2910:50 pmGRU - DSM
1 stop20h 49mDelta
Deal found 6/12$1,119
This Ovago deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/146:30 pmDSM - GRU
2 stops23h 30mLATAM Airlines
lun. 9/2911:55 amGRU - DSM
2 stops24h 23mLATAM Airlines
Deal found 6/12$1,131
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/84:08 pmDSM - GRU
1 stop13h 07mAmerican Airlines
lun. 9/2210:00 pmGRU - DSM
1 stop21h 35mAmerican Airlines
Deal found 6/12$1,179
This deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/313:38 pmDSM - GRU
1 stop15h 52mUnited Airlines
jue. 8/2810:20 pmGRU - DSM
1 stop16h 03mUnited Airlines
Deal found 6/11$1,239
This Vliegwinkel deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Vliegwinkel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/256:50 pmDSM - GRU
1 stop12h 40mLufthansa
vie. 8/110:20 pmGRU - DSM
1 stop14h 12mLufthansa
Deal found 6/10$1,355
This FlightHub deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/148:00 amDSM - GRU
2 stops19h 35mAvianca
dom. 9/281:45 amGRU - DSM
2 stops22h 05mAvianca
Deal found 6/12$1,393
This lastminute.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/268:00 amDSM - GRU
2 stops20h 30mCopa Airlines
vie. 8/11:40 amGRU - DSM
2 stops18h 09mCopa Airlines
Deal found 6/11$1,481

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Des Moines to Sao Paulo that are best for you.

Fly from

Des Moines

Fly to

Sao Paulo

Route

Depart

Return

Price

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

vie. 7/25

6:30 am-9:10 pm

3 stops36h 40m

Sao Paulo Guarulhos Intl

vie. 8/1

9:40 pm-5:16 pm

2 stops21h 36m

$1,011

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

lun. 9/8

11:23 am-6:15 am

2 stops16h 52m

Sao Paulo Guarulhos Intl

lun. 9/22

10:50 pm-1:28 pm

1 stop16h 38m

$1,119

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

lun. 9/8

4:08 pm-7:15 am

1 stop13h 07m

Sao Paulo Guarulhos Intl

lun. 9/22

10:00 pm-5:35 pm

1 stop21h 35m

$1,179

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

jue. 7/31

3:38 pm-9:30 am

1 stop15h 52m

Sao Paulo Guarulhos Intl

jue. 8/28

10:20 pm-12:23 pm

1 stop16h 03m

$1,239

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

vie. 8/1

6:40 pm-6:50 am

2 stops34h 10m

Sao Paulo Guarulhos Intl

sáb. 8/30

11:05 pm-10:43 pm

2 stops25h 38m

$1,334

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

vie. 7/25

6:50 pm-9:30 am

1 stop12h 40m

Sao Paulo Guarulhos Intl

vie. 8/1

10:20 pm-10:32 am

1 stop14h 12m

$1,355

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

sáb. 7/26

8:00 am-6:30 am

2 stops20h 30m

Sao Paulo Guarulhos Intl

vie. 8/1

1:40 am-5:49 pm

2 stops18h 09m

$1,481

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

lun. 9/8

8:00 am-5:35 am

2 stops19h 35m

Sao Paulo Guarulhos Intl

jue. 9/18

1:45 am-9:45 pm

2 stops22h 00m

$2,044

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

lun. 9/15

8:00 am-2:57 am

3 stops40h 57m

$373

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

lun. 9/15

5:11 am-7:15 am

1 stop24h 04m

$558

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 12 results
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Best time to book a flight from Des Moines to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Sao Paulo

Rainfall in Sao Paulo by month

Plan your trip to Sao Paulo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Sao Paulo ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit Sao Paulo when rainfall is around 0.8 in.

Temperature in Sao Paulo by month

Plan your trip to Sao Paulo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Sao Paulo, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing Sao Paulo

Get insights into the airlines that provide service to Sao Paulo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Sao Paulo. Reviews last updated junio 12, 2025.
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,785 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Sao Paulo?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Sao Paulo from Des Moines. Booking flights from Des Moines (DSM) to Sao Paulo should be relatively easy as there are 0 daily outbound flights to Sao Paulo from 2 different airlines.

  • What are the cheapest airlines flying from Des Moines to Sao Paulo round-trip?

    Flying on Delta is currently your cheapest option to Sao Paulo, with prices starting at $1,119. Additional round-trip tickets that might be worth considering are offered by LATAM Airlines and American Airlines, with the lowest prices starting at $1,131 and $1,179, respectively. Delta is currently priced 4% below the average price you’ll pay for this route.

  • Can I find deals for flights from Des Moines to Sao Paulo that include hotel bookings?

    Yes. In addition to deals on Des Moines to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Sao Paulo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Sao Paulo.

  • Can I find deals for business class flights from Des Moines to Sao Paulo?

    Yes. Cheapflights offers flight deals from Des Moines to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Sao Paulo?

    Currently, April is the cheapest month in which you can book a flight from Des Moines to Sao Paulo (average of $687). Flying from Des Moines to Sao Paulo in December is currently the most expensive (average of $1,209). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Sao Paulo

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Guarulhos Intl flights
Omaha to Guarulhos Intl flights
Moline to Guarulhos Intl flights

Top 2 airlines flying from Des Moines to Sao Paulo

Discover the top 2 airlines that operate flights from Des Moines to Sao Paulo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$677Average$747FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$861Average$1,060FlexibilityNo cancel feeOn-time71%

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