How long is the flight from Des Moines to Sao Paulo?

For as low as $1,197, LATAM Airlines can have you in Sao Paulo from Des Moines in 16h 27m. Airlines will cover a distance of 5405 mi.

In terms of precipitation, rainfall in Sao Paulo ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit Sao Paulo when rainfall is around 0.8 in.

If weather is an important factor for your trip to Sao Paulo, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

What is the cheapest time of day to fly from DSM to SAO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Sao Paulo as you normally would.

Most accurate provider : When it comes to deals on Des Moines-Sao Paulo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Sao Paulo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Sao Paulo flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Sao Paulo flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Sao Paulo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airport do you fly from for flights from Des Moines to Sao Paulo?

Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Sao Paulo from Des Moines. Booking flights from Des Moines (DSM) to Sao Paulo should be relatively easy as there are 0 daily outbound flights to Sao Paulo from 0 different airlines.

Can I find deals for flights from Des Moines to Sao Paulo that include hotel bookings?

Yes. In addition to deals on Des Moines to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Sao Paulo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Sao Paulo.

Can I find deals for business class flights from Des Moines to Sao Paulo?

Yes. Cheapflights offers flight deals from Des Moines to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$391+ Flights from Des Moines to Sao Paulo, Brazil

Q: How much does it cost to fly round-trip from Des Moines to Sao Paulo?

Airfare is below average for this route at the moment. Des Moines to Sao Paulo flights typically cost between $1,077 and $1,571 in January. The cheapest round-trip price found within the last 3 days was $912 on Multiple Airlines (Jan 22-Jan 28).

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Cheap flight deals from Des Moines to Sao Paulo

Cheapest flights from Des Moines to Sao Paulo
Explore the most affordable flight options available from Des Moines to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

Mon 12/156:35 amDSM - GRU

1 stop21h 20mMultiple Airlines

Tue 1/207:45 pmGRU - DSM

2 stops54h 01mMultiple Airlines

Deal found 12/13

$1,313

Sun 12/142:16 pmDSM - GRU

2 stops23h 14mLATAM Airlines

Tue 1/202:20 pmGRU - DSM

2 stops23h 21mLATAM Airlines

Deal found 12/13

$1,505

Mon 12/155:34 amDSM - GRU

2 stops22h 51mLATAM Airlines

Tue 1/207:30 amGRU - DSM

2 stops17h 59mLATAM Airlines

Deal found 12/13

$1,507

Mon 12/1511:35 amDSM - GRU

1 stop16h 40mUnited Airlines

Tue 1/209:45 pmGRU - DSM

1 stop16h 10mUnited Airlines

Deal found 12/13

$1,515

Sun 12/1411:35 amDSM - GRU

1 stop16h 40mUnited Airlines

Tue 1/209:45 pmGRU - DSM

1 stop16h 10mUnited Airlines

Deal found 12/13

$1,528

Sun 12/142:16 pmDSM - GRU

2 stops15h 34mLATAM Airlines

Thu 12/2510:40 pmGRU - DSM

2 stops21h 35mLATAM Airlines

Deal found 12/13

$1,672

Wed 12/172:16 pmDSM - GRU

2 stops23h 09mLATAM Airlines

Mon 12/2210:40 amGRU - DSM

1 stop14h 51mLATAM Airlines

Deal found 12/12

$1,682

Wed 12/173:17 pmDSM - GRU

2 stops16h 03mUnited Airlines

Mon 12/229:45 pmGRU - DSM

1 stop16h 05mUnited Airlines

Deal found 12/12

$1,690

Sun 12/146:50 pmDSM - GRU

2 stops35h 40mUnited Airlines

Thu 12/259:45 pmGRU - DSM

1 stop19h 48mUnited Airlines

Deal found 12/13

$1,695

Best flights from Des Moines to Sao Paulo
Discover carefully curated flight deals from Des Moines to Sao Paulo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 14, 2025.

Wed 1/285:16 pmDSM - GRU

1 stop13h 19mMultiple Airlines

Wed 2/49:15 pmGRU - DSM

2 stops27h 54mMultiple Airlines

Deal found 12/14

$1,154

Mon 3/211:28 amDSM - GRU

2 stops16h 27mLATAM Airlines

Tue 3/1010:55 pmGRU - DSM

2 stops19h 36mLATAM Airlines

Deal found 12/12

$1,197

Mon 3/211:27 amDSM - GRU

1 stop17h 43mAmerican Airlines

Tue 3/1011:00 pmGRU - DSM

1 stop17h 56mAmerican Airlines

Deal found 12/12

$1,200

Thu 1/158:30 amDSM - GRU

3 stops28h 45mMultiple Airlines

Wed 3/45:25 pmGRU - DSM

3 stops32h 26mMultiple Airlines

Deal found 12/12

$1,155

Sun 3/15:15 pmDSM - GRU

2 stops23h 45mLATAM Airlines

Mon 3/910:40 amGRU - DSM

1 stop13h 58mLATAM Airlines

Deal found 12/12

$1,197

Sun 3/13:26 pmDSM - GRU

1 stop13h 44mAmerican Airlines

Mon 3/911:00 pmGRU - DSM

1 stop17h 56mAmerican Airlines

Deal found 12/12

$1,240

Tue 1/275:16 pmDSM - GRU

1 stop13h 19mMultiple Airlines

Tue 2/39:00 pmGRU - DSM

2 stops45h 40mMultiple Airlines

Deal found 12/13

$1,221

Tue 1/2711:26 amDSM - GRU

2 stops19h 29mLATAM Airlines

Tue 2/311:45 pmGRU - DSM

1 stop13h 56mLATAM Airlines

Deal found 12/12

$1,240

Wed 1/2811:26 amDSM - GRU

1 stop15h 14mLATAM Airlines

Wed 2/411:45 pmGRU - DSM

1 stop13h 56mLATAM Airlines

Deal found 12/14

$1,253

Last-minute flights from Des Moines to Sao Paulo
Discover last-minute flight deals from Des Moines to Sao Paulo. Data last updated December 14, 2025 and is based on user searches.

Thu 1/158:30 amDSM - GRU

3 stops28h 45mMultiple Airlines

Wed 3/45:25 pmGRU - DSM

2 stops32h 26mMultiple Airlines

Deal found 12/12

$994

Thu 1/228:30 amDSM - GRU

3 stops35h 10mMultiple Airlines

Wed 1/281:20 amGRU - DSM

2 stops24h 26mMultiple Airlines

Deal found 12/13

$912

Mon 1/265:21 amDSM - GRU

1 stop23h 49mAmerican Airlines

Mon 2/210:00 pmGRU - DSM

1 stop15h 50mAmerican Airlines

Deal found 12/12

$1,266

Mon 1/2611:30 amDSM - GRU

1 stop16h 45mUnited Airlines

Mon 2/210:25 pmGRU - DSM

2 stops19h 08mUnited Airlines

Deal found 12/11

$1,267

Tue 1/275:16 pmDSM - GRU

1 stop13h 19mMultiple Airlines

Tue 2/311:45 pmGRU - DSM

2 stops42h 55mMultiple Airlines

Deal found 12/13

$1,187

Tue 1/2711:26 amDSM - GRU

2 stops19h 29mLATAM Airlines

Tue 2/311:45 pmGRU - DSM

1 stop13h 56mLATAM Airlines

Deal found 12/12

$1,240

Wed 1/285:16 pmDSM - GRU

1 stop13h 19mMultiple Airlines

Wed 2/49:15 pmGRU - DSM

2 stops27h 54mMultiple Airlines

Deal found 12/14

$1,154

Wed 1/2811:26 amDSM - GRU

1 stop15h 14mLATAM Airlines

Wed 2/411:45 pmGRU - DSM

1 stop13h 56mLATAM Airlines

Deal found 12/14

$1,253

One-way flights from Des Moines to Sao Paulo
Search for one-way flight options from Des Moines to Sao Paulo. Find affordable one-way fares based on user searches. Data last updated December 14, 2025.

Mon 1/193:34 pmDSM - GRU

3 stops46h 36mMultiple Airlines

Deal found 12/13

$391

Sun 1/258:00 amDSM - GRU

2 stops19h 30mCopa Airlines

Deal found 12/12

$594

Fri 5/151:46 pmDSM - GRU

1 stop17h 14mAmerican Airlines

Deal found 12/14

$596

Mon 1/1911:26 amDSM - GRU

1 stop15h 14mLATAM Airlines

Deal found 12/13

$656

Sun 1/256:48 pmDSM - GRU

1 stop33h 27mUnited Airlines

Deal found 12/12

$671

Find flight deals from Des Moines to Sao Paulo

Most accurate provider	FlightHub 3 stars
Most trusted provider	Expedia 3 stars
Round-trip from	$912 (Mytrip)
One-way from	$391 (Kiwi.com)
Popular in	June
Cheapest in	April
Average price	$1,405

Provider with most accurate pricing for Des Moines-Sao Paulo (SAO) flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Sao Paulo (SAO) flights.

Search Deals

From Des Moines to Sao Paulo (SAO)

Search Deals

One-way flight from Des Moines to Sao Paulo (SAO)

Search Deals

Highest demand for flights based on searches. 18% potential increase in price ($279 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 9% potential price decrease ($103 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 1/28

5:16 pm-9:35 am

1 stop13h 19m

Sao Paulo Guarulhos Intl

Wed 2/4

9:15 pm-10:09 pm

2 stops27h 54m

$1,154

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 1/15

8:30 am-4:15 pm

3 stops28h 45m

Sao Paulo Guarulhos Intl

Wed 3/4

5:25 pm-10:51 pm

3 stops32h 26m

$1,155

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 3/2

11:28 am-6:55 am

2 stops16h 27m

Sao Paulo Guarulhos Intl

Tue 3/10

10:55 pm-4:31 pm

2 stops19h 36m

$1,197

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 3/1

5:15 pm-8:00 pm

2 stops23h 45m

Sao Paulo Guarulhos Intl

Mon 3/9

10:40 am-10:38 pm

1 stop13h 58m

$1,197

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 3/2

11:27 am-8:10 am

1 stop17h 43m

Sao Paulo Guarulhos Intl

Tue 3/10

11:00 pm-2:56 pm

1 stop17h 56m

$1,200

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 1/27

5:16 pm-9:35 am

1 stop13h 19m

Sao Paulo Guarulhos Intl

Tue 2/3

9:00 pm-3:40 pm

2 stops45h 40m

$1,221

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 3/1

3:26 pm-8:10 am

1 stop13h 44m

Sao Paulo Guarulhos Intl

Mon 3/9

11:00 pm-2:56 pm

1 stop17h 56m

$1,240

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 1/27

11:26 am-9:55 am

2 stops19h 29m

Sao Paulo Guarulhos Intl

Tue 2/3

11:45 pm-10:41 am

1 stop13h 56m

$1,240

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 1/28

11:26 am-5:40 am

1 stop15h 14m

Sao Paulo Guarulhos Intl

Wed 2/4

11:45 pm-10:41 am

1 stop13h 56m

$1,253

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 1/19

3:34 pm-5:10 pm

3 stops46h 36m

$391

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 14 results

Compare providers for flights from Des Moines to Sao Paulo

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Sao Paulo in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Sao Paulo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Sao Paulo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Sao Paulo flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Sao Paulo flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Sao Paulo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Sao Paulo

How much does it cost to fly round-trip from Des Moines to Sao Paulo?

Related info for your journey

What airport do you fly from for flights from Des Moines to Sao Paulo?
Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Sao Paulo from Des Moines. Booking flights from Des Moines (DSM) to Sao Paulo should be relatively easy as there are 0 daily outbound flights to Sao Paulo from 0 different airlines.
How long is the flight from Des Moines to Sao Paulo?
For as low as $1,197, LATAM Airlines can have you in Sao Paulo from Des Moines in 16h 27m. Airlines will cover a distance of 5405 mi.
Can I find deals for flights from Des Moines to Sao Paulo that include hotel bookings?
Yes. In addition to deals on Des Moines to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Sao Paulo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Sao Paulo.
Can I find deals for business class flights from Des Moines to Sao Paulo?
Yes. Cheapflights offers flight deals from Des Moines to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$391+ Cheap flights from Des Moines (DSM) to Sao Paulo, Brazil (SAO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Sao Paulo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to Sao Paulo

Cheapest flights from Des Moines to Sao PauloExplore the most affordable flight options available from Des Moines to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

Explore the most affordable flight options available from Des Moines to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

Find flight deals from Des Moines to Sao Paulo

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Sao Paulo that are best for you.

Compare providers for flights from Des Moines to Sao Paulo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Sao Paulo in December.

Best time to book a flight from Des Moines to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Sao Paulo

How much does it cost to fly round-trip from Des Moines to Sao Paulo?

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to Sao Paulo?

How long is the flight from Des Moines to Sao Paulo?

Can I find deals for flights from Des Moines to Sao Paulo that include hotel bookings?

How can I find direct flights from Des Moines to Sao Paulo?

Can I find deals for business class flights from Des Moines to Sao Paulo?

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Cheapest flights from Des Moines to Sao Paulo
Explore the most affordable flight options available from Des Moines to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.