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Santo Domingo

$396+ Cheap flights from Santa Cruz de la Sierra (VVI) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SDQ
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from Santa Cruz de la Sierra Viru Viru Intl to Santo Domingo Las Americas are usually found in February or November, booked 39 days in advance, depart on a Tuesday or Friday and return on a Monday

Cheap flight deals from Santa Cruz de la Sierra to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 17, 2025.

Round-trip from

$704
(Copa Airlines)

One-way from

$396
(Copa Airlines)

Popular in

April

Cheapest in

February

Average price

$683
From Santa Cruz de la Sierra Viru Viru Intl to Santo Domingo Las Americas
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One-way flight from Santa Cruz de la Sierra Viru Viru Intl to Santo Domingo Las Americas
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Highest demand for flights based on searches. 2% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Santa Cruz de la Sierra to Santo Domingo

Cheapest flights from Santa Cruz de la Sierra to Santo Domingo
Explore the most affordable flight options available from Santa Cruz de la Sierra to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/251:09 amVVI - SDQ
1 stop9h 49mCopa Airlines
vie. 10/1011:57 amSDQ - VVI
1 stop15h 39mCopa Airlines
Deal found 9/16$704
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/311:09 amVVI - SDQ
1 stop15h 06mCopa Airlines
mié. 11/122:15 pmSDQ - VVI
1 stop13h 21mCopa Airlines
Deal found 9/16$707
This Copa Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/21:09 amVVI - SDQ
1 stop15h 06mCopa Airlines
lun. 12/152:14 pmSDQ - VVI
1 stop8h 32mCopa Airlines
Deal found 9/17$730
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/252:50 amVVI - SDQ
3 stops34h 17mMultiple Airlines
vie. 10/106:10 pmSDQ - VVI
1 stop7h 40mMultiple Airlines
Deal found 9/16$734
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/11:09 amVVI - SDQ
1 stop12h 03mCopa Airlines
mar. 12/168:55 amSDQ - VVI
1 stop13h 51mCopa Airlines
Deal found 9/16$757
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/171:09 amVVI - SDQ
1 stop15h 06mCopa Airlines
mié. 1/76:39 pmSDQ - VVI
1 stop9h 05mCopa Airlines
Deal found 9/16$785
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/211:09 amVVI - SDQ
1 stop11h 58mCopa Airlines
mié. 10/226:24 pmSDQ - VVI
1 stop9h 12mCopa Airlines
Deal found 9/16$808
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/251:09 amVVI - SDQ
1 stop10h 31mCopa Airlines
sáb. 1/102:11 pmSDQ - VVI
1 stop8h 39mCopa Airlines
Deal found 9/16$843
This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/191:09 amVVI - SDQ
1 stop15h 06mCopa Airlines
vie. 1/212:40 pmSDQ - VVI
1 stop10h 10mCopa Airlines
Deal found 9/16$861

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Santo Domingo that are best for you.

Fly from

Santa Cruz de la Sierra

Fly to

Santo Domingo

Route

Depart

Return

Price

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

jue. 10/9

1:09 am-4:15 pm

1 stop15h 06m

Santo Domingo Las Americas

lun. 10/20

8:58 am-3:36 am

1 stop18h 38m

$704

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

dom. 3/1

1:14 am-1:11 pm

1 stop11h 57m

Santo Domingo Las Americas

dom. 3/8

2:13 pm-10:50 pm

1 stop8h 37m

$707

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

sáb. 11/1

11:40 am-2:26 am

1 stop14h 46m

Santo Domingo Las Americas

mié. 11/12

2:15 pm-3:36 am

1 stop13h 21m

$707

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

mar. 12/2

1:09 am-4:15 pm

1 stop15h 06m

Santo Domingo Las Americas

lun. 12/15

2:14 pm-10:46 pm

1 stop8h 32m

$730

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

mar. 10/21

1:09 am-10:56 am

1 stop9h 47m

$396

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

dom. 10/5

1:05 pm-9:15 am

3 stops20h 10m

$397

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

mar. 10/7

5:20 am-9:15 am

1 stop27h 55m

$400

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

jue. 10/9

11:59 am-10:25 pm

1 stop10h 26m

$425

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

jue. 10/9

2:50 am-4:29 pm

2 stops13h 39m

$435

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

mié. 10/8

2:50 am-4:07 pm

2 stops37h 17m

$445

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 13 results
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Best time to book a flight from Santa Cruz de la Sierra to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Santo Domingo

How far ahead should I book a flight from Santa Cruz de la Sierra to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Santa Cruz de la Sierra to Santo Domingo. Price data was last updated on September 12, 2025.

The price you pay for your flight from Santa Cruz de la Sierra to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 39 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santo Domingo (average of $362). Flying from Santa Cruz de la Sierra to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santa Cruz de la Sierra to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated septiembre 17, 2025.
Read reviews from past customers who have flown Copa Airlines and Avianca from Santa Cruz de la Sierra to Santo Domingo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,533 reviews

Entertainment

6.8

Food

6.8

Comfort

7.4

Overall

7.6

Boarding

7.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,533 reviews
Copa Airlines
7.6
Good
1,533 reviews

Entertainment

6.8

Food

6.8

Comfort

7.4

Overall

7.6

Boarding

7.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,436 reviews
Copa Airlines
7.6
Good
1,533 reviews

Entertainment

6.8

Food

6.8

Comfort

7.4

Overall

7.6

Boarding

7.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to Santo Domingo?

    Departing from Santa Cruz de la Sierra to Santo Domingo will take you 15h 06m. There are 2530 mi between Santa Cruz de la Sierra and Santo Domingo.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to Santo Domingo round-trip?

    According to our current data, Copa Airlines ($628), and Avianca ($674) offers the cheapest pricing from Santa Cruz de la Sierra to Santo Domingo. Copa Airlines is currently priced 14% below the average price you’ll pay for this route.

  • Can I find deals for flights from Santa Cruz de la Sierra to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Santo Domingo.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Santo Domingo?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santo Domingo (average of $362). Flying from Santa Cruz de la Sierra to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Santa Cruz de la Sierra to Santo Domingo

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Top 2 airlines flying from Santa Cruz de la Sierra to Santo Domingo

Discover the top 2 airlines that operate flights from Santa Cruz de la Sierra to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$628Average$860FlexibilityNo cancel feeOn-time70%
AviancaCheapest$674Average$853FlexibilityNo cancel feeOn-time71%

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