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Santo Domingo

$450+ Cheap flights from Santa Cruz de la Sierra (VVI) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — SDQ
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
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Cheap flight deals from Santa Cruz de la Sierra to Santo Domingo

Cheapest flights from Santa Cruz de la Sierra to Santo Domingo
Explore the most affordable flight options available from Santa Cruz de la Sierra to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This Copa Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:12 am
VVI
-
SDQ
1 stop12h 01m
Copa Airlines
Wed 5/66:39 pm
SDQ
-
VVI
1 stop8h 52m
Copa Airlines
Deal found 3/20$747
This Copa Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/281:14 am
VVI
-
SDQ
1 stop10h 17m
Copa Airlines
Sat 5/912:40 pm
SDQ
-
VVI
1 stop9h 58m
Copa Airlines
Deal found 3/19$770
This Avianca deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/33:35 am
VVI
-
SDQ
1 stop14h 20m
Avianca
Tue 8/116:50 pm
SDQ
-
VVI
1 stop7h 40m
Avianca
Deal found 3/23$850
This Copa Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/31:12 am
VVI
-
SDQ
1 stop10h 30m
Copa Airlines
Tue 8/1112:43 pm
SDQ
-
VVI
1 stop9h 57m
Copa Airlines
Deal found 3/20$864
This Copa Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:12 am
VVI
-
SDQ
1 stop15h 03m
Copa Airlines
Mon 7/1312:43 pm
SDQ
-
VVI
1 stop14h 52m
Copa Airlines
Deal found 3/18$1,015
This FlightHub deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/223:35 am
VVI
-
SDQ
1 stop14h 20m
Multiple Airlines
Tue 5/58:45 am
SDQ
-
VVI
2 stops31h 05m
Multiple Airlines
Deal found 3/19$1,149
This Justfly.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/33:35 am
VVI
-
SDQ
1 stop14h 20m
Multiple Airlines
Tue 8/116:50 pm
SDQ
-
VVI
2 stops13h 20m
Multiple Airlines
Deal found 3/20$1,151
This Copa Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/271:12 am
VVI
-
SDQ
1 stop10h 30m
Copa Airlines
Thu 7/912:13 pm
SDQ
-
VVI
1 stop10h 27m
Copa Airlines
Deal found 3/18$1,370
This Copa Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/271:12 am
VVI
-
SDQ
1 stop15h 03m
Copa Airlines
Fri 7/102:17 pm
SDQ
-
VVI
1 stop8h 23m
Copa Airlines
Deal found 3/19$1,425

Find flight deals from Santa Cruz de la Sierra to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$747
(Copa Airlines)

One-way from

$450
(Copa Airlines)

Popular in

April

Cheapest in

September

Average price

$751
Provider with most accurate pricing for Santa Cruz de la Sierra Viru Viru Intl-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Cruz de la Sierra Viru Viru Intl-Santo Domingo Las Americas flights.
Search Deals
From Santa Cruz de la Sierra Viru Viru Intl to Santo Domingo Las Americas
Search Deals
One-way flight from Santa Cruz de la Sierra Viru Viru Intl to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

Fri 5/1

1:12 am-1:13 pm

1 stop12h 01m

Santo Domingo Las Americas

Wed 5/6

6:39 pm-3:31 am

1 stop8h 52m

$747

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

Wed 4/22

1:15 am-11:41 am

1 stop10h 26m

Santo Domingo Las Americas

Tue 5/5

6:04 am-10:38 pm

1 stop16h 34m

$747

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/28

1:14 am-1:11 pm

1 stop11h 57m

Santo Domingo Las Americas

Sat 5/9

8:45 am-10:38 pm

1 stop13h 53m

$770

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

Wed 4/22

3:35 am-5:55 pm

1 stop14h 20m

Santo Domingo Las Americas

Tue 5/5

8:45 am-3:50 pm

2 stops31h 05m

$1,149
Cheapest one-way
Quickest one-way

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/6

1:15 am-11:41 am

1 stop10h 26m

$450

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/2

11:47 am-2:25 am

1 stop14h 38m

$450

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/7

1:15 am-4:14 pm

1 stop14h 59m

$450

Santa Cruz de la SierraSanto Domingo

VVI - SDQ

VVISDQ

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/6

11:48 am-11:55 am

2 stops24h 07m

$1,370

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Cruz de la Sierra-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Cruz de la Sierra to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Santo Domingo

How far ahead should I book a flight from Santa Cruz de la Sierra to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Santa Cruz de la Sierra to Santo Domingo. Price data was last updated on March 13, 2026.

The price you pay for your flight from Santa Cruz de la Sierra to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 7 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santo Domingo?

Currently, March is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santo Domingo (average of $292). Flying from Santa Cruz de la Sierra to Santo Domingo in January is currently the most expensive (average of $706). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santa Cruz de la Sierra to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated March 23, 2026.
Read reviews from past customers who have flown Copa Airlines and Avianca from Santa Cruz de la Sierra to Santo Domingo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,575 reviews

Crew

8.1

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Food

6.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Copa Airlines
7.5
Good
1,575 reviews
Copa Airlines
7.5
Good
1,575 reviews

Crew

8.1

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Food

6.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.
Avianca
6.5
Okay
2,505 reviews
Copa Airlines
7.5
Good
1,575 reviews

Crew

8.1

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Food

6.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Katerine,Mar 2026

LAX - PTY

Really i was expecting be more friendly with family’s, more when you travel with a infant. We expected like a priority to boarding or be friendly with the spots on the aeroplane.

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to Santo Domingo?

    Departing from Santa Cruz de la Sierra to Santo Domingo will take you 12h 01m. There are 2530 mi between Santa Cruz de la Sierra and Santo Domingo.

  • What are the cheapest airlines flying from Santa Cruz de la Sierra to Santo Domingo round-trip?

    According to our current data, Copa Airlines ($628), and Avianca ($697) offers the cheapest pricing from Santa Cruz de la Sierra to Santo Domingo. Copa Airlines is currently priced 17% below the average price you’ll pay for this route.

  • Can I find deals for flights from Santa Cruz de la Sierra to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Santo Domingo.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Santo Domingo?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Santo Domingo?

    Currently, March is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Santo Domingo (average of $292). Flying from Santa Cruz de la Sierra to Santo Domingo in January is currently the most expensive (average of $706). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 2 airlines flying from Santa Cruz de la Sierra to Santo Domingo

Discover the top 2 airlines that operate flights from Santa Cruz de la Sierra to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$628Average$803FlexibilityNo cancel feeOn-time70%
AviancaCheapest$697Average$853FlexibilityNo cancel feeOn-time71%

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