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Santo Domingo

$168+ Cheap flights from Panama City (PTY) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDQ
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Santo Domingo Las Americas are usually found in June or July, booked 62 days in advance, depart on a Thursday or Monday and return on a Wednesday

Cheap flight deals from Panama City to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$292
(Gotogate)

One-way from

$270

Popular in

December

Cheapest in

June

Average price

$417

Good round-trip deal

$428 or less

Good one-way deal

$473 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Santo Domingo Las Americas flights.
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From Panama City Tocumen Intl to Santo Domingo Las Americas
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One-way flight from Panama City Tocumen Intl to Santo Domingo Las Americas
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Highest demand for flights based on searches. 5% potential increase in price ($20 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Santo Domingo Las Americas.
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Price to beat on a one-way flight from Panama City Tocumen Intl to Santo Domingo Las Americas.
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Find flight deals from Panama City to Santo Domingo

Cheapest flights from Panama City to Santo Domingo
Explore the most affordable flight options available from Panama City to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This Avianca deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/185:25 pmPTY - SDQ
1 stop16h 25mAvianca
Fri 5/306:10 pmSDQ - PTY
1 stop15h 45mAvianca
Deal found 4/29$294
This Trip.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/411:05 amPTY - SDQ
1 stop5h 10mMultiple Airlines
Sat 6/146:54 amSDQ - PTY
2 stops18h 16mMultiple Airlines
Deal found 4/29$317
This Copa Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/157:26 amPTY - SDQ
Nonstop2h 31mCopa Airlines
Sun 5/185:21 amSDQ - PTY
Nonstop2h 37mCopa Airlines
Deal found 4/29$429
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/197:55 amPTY - SDQ
2 stops16h 55mUnited Airlines
Thu 6/193:20 pmSDQ - PTY
2 stops25h 52mUnited Airlines
Deal found 4/29$857
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/122:13 pmPTY - SDQ
2 stops27h 15mDelta
Tue 5/207:00 amSDQ - PTY
2 stops30h 48mDelta
Deal found 4/29$5,776

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Panama City to Santo Domingo that are best for you.

Fly from

Panama City

Fly to

Santo Domingo

Route

Depart

Return

Price

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Sun 5/18

5:25 pm-10:50 am

1 stop16h 25m

Santo Domingo Las Americas

Fri 5/30

6:10 pm-8:55 am

1 stop15h 45m

$294

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Wed 6/4

11:05 am-5:15 pm

1 stop5h 10m

Santo Domingo Las Americas

Sat 6/14

6:54 am-12:10 am

2 stops18h 16m

$317

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Thu 5/15

7:26 am-10:57 am

Nonstop2h 31m

Santo Domingo Las Americas

Sun 5/18

5:21 am-6:58 am

Nonstop2h 37m

$429

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Mon 5/19

7:55 am-1:50 am

2 stops16h 55m

Santo Domingo Las Americas

Thu 6/19

3:20 pm-4:12 pm

2 stops25h 52m

$857

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Mon 5/12

2:13 pm-6:28 pm

2 stops27h 15m

Santo Domingo Las Americas

Tue 5/20

7:00 am-12:48 pm

2 stops30h 48m

$5,776

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Fri 5/2

10:05 pm-10:50 am

1 stop11h 45m

$168

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Sun 6/1

6:34 pm-2:19 pm

2 stops18h 45m

$235

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Fri 5/2

9:37 am-1:10 pm

Nonstop2h 33m

$474

Panama CitySanto Domingo

PTY - SDQ

PTYSDQ

Panama City Tocumen Intl

Tue 5/27

7:55 am-1:50 am

2 stops16h 55m

$1,573

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Compare providers for flights from Panama City to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Santo Domingo in April.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santo Domingo

How far ahead should I book a flight from Panama City to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Santo Domingo. Price data was last updated on April 25, 2025.

The price you pay for your flight from Panama City to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 62 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Panama City to Santo Domingo (average of $362). Flying from Panama City to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SDQ?

Find hourly flight availability from Panama City to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

One of the essential ways to save on airfare from Panama City to Santo Domingo is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 6% on airfare.

Rainfall in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

Temperature in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated April 29, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines and United Airlines from Panama City to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.
Copa Airlines
7.5
Good
1,411 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.
Avianca
6.7
Okay
2,317 reviews
Delta
8.0
Very good
7,929 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
4.0
Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Santo Domingo?

    If you book a flight from Panama City to Santo Domingo, you will be flying from Tocumen Intl to Las Americas. Flights to Santo Domingo Las Americas (SDQ) from Panama City Tocumen Intl (PTY) take 2h 31m for a nonstop flight. There is 1 flight from Tocumen Intl to Santo Domingo per day from 2 airlines.

  • How popular is this Panama City to Santo Domingo flight route?

    The Panama City Tocumen Intl to Santo Domingo Las Americas flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Panama City to Santo Domingo round-trip?

    Cheapflights users have booked flights from Panama City to Santo Domingo round-trip from $292. Other airlines that can offer you cheap pricing are Copa Airlines, from $429, and United Airlines, from $857. These flights start at 26% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Panama City to Santo Domingo one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $270. Copa Airlines flights start at $474 while deals on United Airlines start at $1,573 one-way.

  • What are the most reliable airlines from Panama City to Santo Domingo?

    No one likes to see their flight delayed. When booking a flight from Panama City to Santo Domingo consider choosing Air France (97%), Turkish Airlines (97%) or Copa Airlines (97%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Panama City to Santo Domingo?

    Looking for the cheapest flight from Panama City to Santo Domingo? While on average our users pay $451, our data indicates the cheapest price to be $428. The most popular route (Panama City Tocumen Intl - Santo Domingo Las Americas), is priced around $363.

  • Can I find deals for flights from Panama City to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Panama City to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santo Domingo.

  • Can I find deals for business class flights from Panama City to Santo Domingo?

    Yes. Cheapflights offers flight deals from Panama City to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Santo Domingo (average of $362). Flying from Panama City to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Panama City to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Punta Cana flights
Panama City to Santiago de los Caballeros flights

Top 2 airlines flying from Panama City to Santo Domingo

Discover the top 2 airlines that operate flights from Panama City to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$288Average$349FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$345Average$417FlexibilityNo cancel feeOn-time70%

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