How long is the flight from Odessa to Santo Domingo?

American Airlines and United Airlines can get you from Odessa to Santo Domingo in just under 16h 59m. Your travel time can differ by up to 11h 12m. The distance from Odessa to Santo Domingo is about 2225 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What is the cheapest time of day to fly from OD3 to SDQ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Odessa to Santo Domingo as you normally would.

What airport do you fly into for flights to Santo Domingo from Odessa?

If you book a flight to Santo Domingo from Odessa, you will be flying to Las Americas, which is the city’s only airport. Santo Domingo Las Americas (SDQ) is located 17.5 mi from the center of Santo Domingo. There are 0 flights from Odessa to Las Americas per day from 0 different airlines.

Can I find deals for flights from Odessa to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Odessa to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Odessa to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to Santo Domingo.

Can I find deals for business class flights from Odessa to Santo Domingo?

Yes. Cheapflights offers flight deals from Odessa to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$653+ Flights from Odessa to Santo Domingo

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Odessa to Santo Domingo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Odessa to Santo Domingo

Cheapest flights from Odessa to Santo Domingo
Explore the most affordable flight options available from Odessa to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.

Sat 5/305:00 am

MAF

SDQ

2 stops16h 59m

American Airlines

Sat 7/182:19 pm

SDQ

MAF

2 stops10h 53m

American Airlines

Deal found 1/19

$653

Thu 10/88:32 pm

MAF

SDQ

2 stops16h 48m

American Airlines

Mon 10/128:00 am

SDQ

MAF

2 stops16h 59m

American Airlines

Deal found 1/17

$858

Tue 2/35:35 pm

MAF

SDQ

2 stops28h 11m

United Airlines

Thu 2/56:00 am

SDQ

MAF

2 stops14h 19m

United Airlines

Deal found 1/17

$1,040

Thu 10/86:00 am

MAF

SDQ

2 stops15h 46m

United Airlines

Mon 10/126:00 am

SDQ

MAF

3 stops18h 30m

United Airlines

Deal found 1/17

$5,882

Best flights from Odessa to Santo Domingo
Discover carefully curated flight deals from Odessa to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 20, 2026.

Sat 5/305:00 am

MAF

SDQ

2 stops16h 59m

American Airlines

Sat 7/182:19 pm

SDQ

MAF

2 stops10h 53m

American Airlines

Deal found 1/19

$653

Tue 2/35:35 pm

MAF

SDQ

2 stops28h 11m

United Airlines

Thu 2/56:00 am

SDQ

MAF

2 stops14h 19m

United Airlines

Deal found 1/17

$1,040

Last-minute flights from Odessa to Santo Domingo
Discover last-minute flight deals from Odessa to Santo Domingo. Data last updated January 20, 2026 and is based on user searches.

Tue 2/35:35 pm

MAF

SDQ

2 stops28h 11m

United Airlines

Thu 2/56:00 am

SDQ

MAF

2 stops14h 19m

United Airlines

Deal found 1/17

$1,040

Find flight deals from Odessa to Santo Domingo

Most accurate provider	FlightHub 3 stars
Most trusted provider	Ovago 2 stars
Round-trip from	$653 (American Airlines)

Provider with most accurate pricing for Midland Intl-Santo Domingo Las Americas flight deals.

Search Deals

Provider most trusted by Cheapflights users for Midland Intl-Santo Domingo Las Americas flights.

Search Deals

From Odessa to Santo Domingo Las Americas

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Odessa to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MidlandSanto Domingo

MAF - SDQ

MAFSDQ

Midland Intl

Sat 5/30

5:00 am-10:59 pm

2 stops16h 59m

Santo Domingo Las Americas

Sat 7/18

2:19 pm-12:12 am

2 stops10h 53m

$653

MidlandSanto Domingo

MAF - SDQ

MAFSDQ

Midland Intl

Tue 2/3

5:35 pm-11:46 pm

2 stops28h 11m

Santo Domingo Las Americas

Thu 2/5

6:00 am-6:19 pm

2 stops14h 19m

$1,040

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Best time to book a flight from Odessa to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Odessa with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to Santo Domingo

No data available for this route at this time. Please check back soon.

Related info for your journey

What airport do you fly into for flights to Santo Domingo from Odessa?
If you book a flight to Santo Domingo from Odessa, you will be flying to Las Americas, which is the city’s only airport. Santo Domingo Las Americas (SDQ) is located 17.5 mi from the center of Santo Domingo. There are 0 flights from Odessa to Las Americas per day from 0 different airlines.
How long is the flight from Odessa to Santo Domingo?
American Airlines and United Airlines can get you from Odessa to Santo Domingo in just under 16h 59m. Your travel time can differ by up to 11h 12m. The distance from Odessa to Santo Domingo is about 2225 mi. This flight may include one or multiple stops.
Can I find deals for flights from Odessa to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Odessa to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Odessa to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to Santo Domingo.
Can I find deals for business class flights from Odessa to Santo Domingo?
Yes. Cheapflights offers flight deals from Odessa to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$653+ Cheap flights from Odessa, TX to Santo Domingo (SDQ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Odessa to Santo Domingo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Odessa to Santo Domingo

Cheapest flights from Odessa to Santo DomingoExplore the most affordable flight options available from Odessa to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.

Explore the most affordable flight options available from Odessa to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.

Find flight deals from Odessa to Santo Domingo

Keep the following information in mind while searching for Odessa to Santo Domingo flight deals. Data was last updated January 20, 2026.

Most accurate provider

Most trusted provider

Round-trip from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Odessa to Santo Domingo that are best for you.

Best time to book a flight from Odessa to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Odessa with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Odessa to Santo Domingo

Related info for your journey

Find useful and relevant information for your journey from Odessa to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santo Domingo from Odessa?

How long is the flight from Odessa to Santo Domingo?

Can I find deals for flights from Odessa to Santo Domingo that include hotel bookings?

How can I find direct flights from Odessa to Santo Domingo?

Can I find deals for business class flights from Odessa to Santo Domingo?

Traveling to a place near Santo Domingo?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Odessa to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Odessa to Santo Domingo
Explore the most affordable flight options available from Odessa to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.