It’s generally more expensive to depart on a Wednesday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.
Due to multiple factors, expect to potentially pay more when booking in November. For low rates, September can be a great choice for travel to Puerto Plata. Flights to Puerto Plata from William P. Hobby in September are about $651 on average during September, but can be found for as low as $258.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from William P. Hobby to Puerto Plata as you normally would.