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Santo Domingo

$180+ Cheap flights from Irvine, CA to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — SDQ
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Irvine to Santo Domingo Las Americas are usually found in September or May, booked 39 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Irvine to Santo Domingo

Keep the following information in mind while searching for Irvine to Santo Domingo flight deals. Data was last updated September 15, 2025.

Round-trip from

$387
(Delta)

One-way from

$180
(Mytrip)

Popular in

December

Cheapest in

September

Average price

$470
From Irvine to Santo Domingo Las Americas
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One-way flight from Irvine to Santo Domingo Las Americas
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Highest demand for flights based on searches. 17% potential increase in price ($131 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($42 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Irvine to Santo Domingo

Cheapest flights from Irvine to Santo Domingo
Explore the most affordable flight options available from Irvine to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/47:00 amLAX - SDQ
1 stop14h 36mDelta
Fri 10/171:49 pmSDQ - LAX
1 stop12h 24mDelta
Deal found 9/14$387
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/21:40 pmLAX - SDQ
1 stop18h 35mAmerican Airlines
Mon 10/67:00 amSDQ - LAX
1 stop13h 23mAmerican Airlines
Deal found 9/13$393
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/154:46 pmLAX - SDQ
2 stops13h 39mAmerican Airlines
Wed 10/224:20 pmSDQ - LAX
1 stop10h 58mAmerican Airlines
Deal found 9/14$397
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/163:25 pmLAX - SDQ
1 stop19h 10mAmerican Airlines
Sun 10/264:50 pmSDQ - LAX
1 stop19h 46mAmerican Airlines
Deal found 9/14$398
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2912:22 pmLAX - SDQ
2 stops24h 38mSpirit Airlines
Mon 10/65:12 pmSDQ - LAX
2 stops27h 20mSpirit Airlines
Deal found 9/15$400
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/179:30 amLAX - SDQ
1 stop12h 06mDelta
Tue 12/28:40 pmSDQ - LAX
1 stop19h 22mDelta
Deal found 9/14$401
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/63:25 pmLAX - SDQ
1 stop15h 00mAmerican Airlines
Mon 10/134:20 pmSDQ - LAX
1 stop20h 16mAmerican Airlines
Deal found 9/15$404
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/178:15 pmLAX - SDQ
2 stops12h 04mAmerican Airlines
Mon 11/246:00 amSDQ - LAX
2 stops12h 50mAmerican Airlines
Deal found 9/13$408
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/129:05 pmLAX - SDQ
1 stop13h 30mAmerican Airlines
Sun 10/194:20 pmSDQ - LAX
1 stop20h 16mAmerican Airlines
Deal found 9/14$409
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/257:00 amLAX - SDQ
1 stop12h 45mAmerican Airlines
Wed 12/36:23 pmSDQ - LAX
1 stop19h 33mAmerican Airlines
Deal found 9/14$410

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Irvine to Santo Domingo that are best for you.

Fly from

Irvine

Fly to

Santo Domingo

Route

Depart

Return

Price

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Sat 10/4

7:00 am-12:36 am

1 stop14h 36m

Santo Domingo Las Americas

Fri 10/17

1:49 pm-11:13 pm

1 stop12h 24m

$387

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Sat 11/15

7:40 am-1:36 am

1 stop13h 56m

Santo Domingo Las Americas

Thu 11/20

6:45 am-2:40 pm

1 stop11h 55m

$401

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Wed 11/19

5:25 am-1:36 am

2 stops16h 11m

Santo Domingo Las Americas

Tue 12/2

6:35 am-11:21 pm

2 stops20h 46m

$406

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Fri 9/26

10:01 pm-3:20 pm

1 stop14h 19m

Santo Domingo Las Americas

Tue 9/30

4:20 pm-11:58 pm

1 stop10h 38m

$433

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Wed 2/11

1:40 pm-4:31 am

1 stop10h 51m

Santo Domingo Las Americas

Mon 2/16

2:35 am-12:19 pm

1 stop13h 44m

$451

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Sun 10/5

2:01 am-10:25 pm

1 stop17h 24m

Santo Domingo Las Americas

Mon 10/13

11:57 am-11:02 pm

1 stop14h 05m

$451

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Fri 11/14

12:07 pm-2:09 am

1 stop10h 02m

Santo Domingo Las Americas

Sat 11/22

11:54 pm-8:18 am

1 stop12h 24m

$451

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Fri 1/16

1:11 am-4:12 pm

1 stop11h 01m

Santo Domingo Las Americas

Mon 1/26

12:40 pm-10:36 pm

1 stop13h 56m

$453

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Wed 10/22

7:49 pm-9:25 am

2 stops10h 36m

Santo Domingo Las Americas

Mon 10/27

2:45 pm-11:15 pm

1 stop11h 30m

$460

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Mon 11/17

10:50 pm-7:08 pm

1 stop16h 18m

Santo Domingo Las Americas

Wed 11/26

8:40 pm-11:52 am

1 stop19h 12m

$461

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 21 results
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Best time to book a flight from Irvine to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santo Domingo

How far ahead should I book a flight from Irvine to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Santo Domingo. Price data was last updated on September 12, 2025.

The best time to book flights from Irvine to Santo Domingo is 39 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Irvine to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Irvine to Santo Domingo (average of $362). Flying from Irvine to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to SDQ?

Find hourly flight availability from Irvine to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Santo Domingo as you normally would.

How much does it cost to fly round-trip from Irvine to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated September 15, 2025.
See what other customers who have flown with Delta, Copa Airlines, and American Airlines from Irvine to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,531 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
JetBlue
7.2
Good
2,912 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Spirit Airlines
6.3
Okay
8,015 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santo Domingo from Irvine?

    Located just 17.5 mi from the city center, Santo Domingo Las Americas is the airport most travelers will use when flying to Santo Domingo from Irvine. Booking flights from Irvine to Las Americas (SDQ) should be relatively easy as there are 0 daily inbound flights from Irvine from 6 different airlines.

  • How long is the flight from Irvine to Santo Domingo?

    Departing from Irvine to Santo Domingo will take you 14h 19m. The distance between Irvine and Santo Domingo is about 3171 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Irvine to Santo Domingo one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $180. However, be on the lookout for offers from United Airlines and Delta, as they are both options that can get you from Irvine to Santo Domingo for a low price.

  • Can I find deals for flights from Irvine to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Irvine to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santo Domingo.

  • Can I find deals for business class flights from Irvine to Santo Domingo?

    Yes. Cheapflights offers flight deals from Irvine to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Irvine to Santo Domingo (average of $362). Flying from Irvine to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 6 airlines flying from Irvine to Santo Domingo

Discover the top 6 airlines that operate flights from Irvine to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$356Average$623FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$449Average$615FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$451Average$581FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$469Average$713FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$470Average$538FlexibilityNo cancel feeOn-time69%
DeltaCheapest$470Average$605FlexibilityNo cancel feeOn-timeN/A

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