What are the cheapest airlines to fly from Irvine to Santo Domingo one-way?

The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $184. However, be on the lookout for offers from Frontier and Copa Airlines, as they are both options that can get you from Irvine to Santo Domingo for a low price.

What is the cheapest day to fly from Irvine to Santo Domingo?

Travelers seeking maximum savings on their Irvine to Santo Domingo flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Thursday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What are the most popular airlines that fly from Irvine to Santo Domingo?

American Airlines, JetBlue and Copa Airlines are the most popular airlines when flying from Irvine to Santo Domingo.

How far in advance should I book a flight from Irvine to Santo Domingo?

Find a great deal and save up to 13% by booking at least 53 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Irvine to Santo Domingo within the next two weeks, with the cheapest ticket starting at $543.

What is the cheapest month to fly from Irvine to Santo Domingo?

The best pricing can be found in the month of September. Prices to Santo Domingo from Irvine average $626. You can even find prices in September for less than $626, as users have found deals to Santo Domingo from as low as $362. The month of December appears to be one of the more expensive times to travel to Santo Domingo from Irvine. Flying in the targeted month can save you up to 70%.

What airport do you fly into for flights to Santo Domingo from Irvine?

Located just 17.5 mi from the city center, Santo Domingo Las Americas is the airport most travelers will use when flying to Santo Domingo from Irvine. Booking flights from Irvine to Las Americas (SDQ) should be relatively easy as there are 0 daily inbound flights from Irvine from 6 different airlines.

Can I find deals for flights from Irvine to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Irvine to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Irvine to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santo Domingo.

Can I find deals for business class flights from Irvine to Santo Domingo?

Yes. Cheapflights offers flight deals from Irvine to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$173+ Flights from Irvine to Santo Domingo

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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Irvine to Santo Domingo Las Americas are usually found in September or May, booked 62 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Irvine to Santo Domingo

Round-trip from	$359 (Kiwi.com)
One-way from	$173 (Kiwi.com)
Popular in	December
Cheapest in	September
Average price	$611

From Irvine to Santo Domingo Las Americas

Search Deals

One-way flight from Irvine to Santo Domingo Las Americas

Search Deals

Highest demand for flights based on searches. 16% potential increase in price ($122 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 7% potential price decrease ($41 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Irvine to Santo Domingo

Cheapest flights from Irvine to Santo Domingo
Explore the most affordable flight options available from Irvine to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2025.

Fri 8/222:15 pmLAX - SDQ

1 stop18h 41mMultiple Airlines

Tue 8/265:05 pmSDQ - LAX

2 stops19h 12mMultiple Airlines

Deal found 7/31

$359

Tue 9/210:31 pmLAX - SDQ

2 stops14h 29mSpirit Airlines

Wed 9/105:05 pmSDQ - LAX

2 stops26h 24mSpirit Airlines

Deal found 7/31

$366

Sat 8/99:28 pmLAX - SDQ

1 stop24h 04mFrontier

Thu 8/211:53 pmSDQ - LAX

2 stops45h 15mFrontier

Deal found 7/30

$451

Thu 10/212:06 pmLAX - SDQ

1 stop19h 50mCopa Airlines

Wed 10/86:24 pmSDQ - LAX

1 stop21h 06mCopa Airlines

Deal found 7/31

$459

Tue 9/210:15 pmLAX - SDQ

1 stop12h 09mJetBlue

Mon 9/152:54 pmSDQ - LAX

1 stop11h 19mJetBlue

Deal found 7/31

$467

Best flights from Irvine to Santo Domingo
Discover carefully curated flight deals from Irvine to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 2, 2025.

Fri 8/222:15 pmLAX - SDQ

1 stop18h 41mMultiple Airlines

Tue 8/265:05 pmSDQ - LAX

2 stops19h 12mMultiple Airlines

Deal found 7/31

$359

Tue 9/210:31 pmLAX - SDQ

2 stops14h 29mSpirit Airlines

Wed 9/105:05 pmSDQ - LAX

2 stops26h 24mSpirit Airlines

Deal found 7/31

$366

Sat 8/99:28 pmLAX - SDQ

1 stop24h 04mFrontier

Thu 8/211:53 pmSDQ - LAX

2 stops45h 15mFrontier

Deal found 7/30

$451

Thu 10/212:06 pmLAX - SDQ

1 stop19h 50mCopa Airlines

Wed 10/86:24 pmSDQ - LAX

1 stop21h 06mCopa Airlines

Deal found 7/31

$459

Tue 9/210:15 pmLAX - SDQ

1 stop12h 09mJetBlue

Mon 9/152:54 pmSDQ - LAX

1 stop11h 19mJetBlue

Deal found 7/31

$467

Thu 8/2112:20 pmLAX - SDQ

1 stop18h 05mAmerican Airlines

Mon 8/257:05 amSDQ - LAX

1 stop19h 03mAmerican Airlines

Deal found 7/31

$471

Last-minute flights from Irvine to Santo Domingo
Discover last-minute flight deals from Irvine to Santo Domingo. Data last updated August 2, 2025 and is based on user searches.

Wed 8/62:50 pmLAX - SDQ

2 stops23h 25mAvianca

Wed 8/136:10 pmSDQ - LAX

2 stops32h 00mAvianca

Deal found 7/31

$561

Thu 8/72:01 amLAX - SDQ

1 stop17h 25mMultiple Airlines

Wed 8/135:05 pmSDQ - LAX

2 stops25h 56mMultiple Airlines

Deal found 7/31

$514

Thu 8/72:01 amLAX - SDQ

1 stop17h 25mCopa Airlines

Tue 8/126:17 pmSDQ - LAX

1 stop31h 45mCopa Airlines

Deal found 7/31

$544

Thu 8/77:00 amLAX - SDQ

1 stop14h 57mDelta

Fri 8/156:00 amSDQ - LAX

1 stop21h 48mDelta

Deal found 7/31

$648

Fri 8/83:30 pmLAX - SDQ

1 stop14h 55mAmerican Airlines

Tue 8/197:05 amSDQ - LAX

1 stop13h 07mAmerican Airlines

Deal found 8/1

$595

Sat 8/99:28 pmLAX - SDQ

1 stop24h 04mFrontier

Thu 8/211:53 pmSDQ - LAX

2 stops45h 15mFrontier

Deal found 7/30

$451

Sat 8/98:10 amLAX - SDQ

3 stops28h 37mSpirit Airlines

Thu 8/215:05 pmSDQ - LAX

2 stops25h 01mSpirit Airlines

Deal found 7/30

$524

Sat 8/91:39 pmLAX - SDQ

1 stop8h 36mJetBlue

Wed 8/202:05 amSDQ - LAX

1 stop11h 56mJetBlue

Deal found 7/30

$674

Sat 8/161:46 amLAX - SDQ

1 stop13h 26mCopa Airlines

Thu 8/288:57 amSDQ - LAX

1 stop17h 15mCopa Airlines

Deal found 7/31

$507

Wed 8/2011:00 amLAX - SDQ

1 stop11h 15mJetBlue

Tue 8/266:05 amSDQ - LAX

1 stop16h 59mJetBlue

Deal found 8/1

$467

Thu 8/2112:20 pmLAX - SDQ

1 stop18h 05mAmerican Airlines

Mon 8/257:05 amSDQ - LAX

1 stop19h 03mAmerican Airlines

Deal found 7/31

$471

Fri 8/222:15 pmLAX - SDQ

1 stop18h 41mMultiple Airlines

Tue 8/265:05 pmSDQ - LAX

2 stops19h 12mMultiple Airlines

Deal found 7/31

$359

One-way flights from Irvine to Santo Domingo
Search for one-way flight options from Irvine to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated August 2, 2025.

Mon 8/111:57 pmLAX - SDQ

2 stops22h 50mMultiple Airlines

Deal found 7/31

$173

Tue 8/265:07 pmLAX - SDQ

2 stops19h 53mSpirit Airlines

Deal found 8/1

$184

Sat 8/161:57 pmLAX - SDQ

1 stop17h 48mFrontier

Deal found 8/1

$188

Sat 9/612:05 pmLAX - SDQ

1 stop19h 53mCopa Airlines

Deal found 7/31

$221

Tue 8/269:40 pmLAX - SDQ

2 stops24h 12mDelta

Deal found 8/1

$224

Tue 8/59:40 pmLAX - SDQ

1 stop8h 45mAmerican Airlines

Deal found 7/31

$248

Sat 9/62:50 pmLAX - SDQ

3 stops23h 25mAvianca

Deal found 7/31

$260

Wed 8/66:14 amLAX - SDQ

1 stop11h 16mBritish Airways

Deal found 7/31

$383

Cheapflights Fare Finder

Use the filters below to find and compare flights from Irvine to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Fri 8/22

2:15 pm-11:56 am

1 stop18h 41m

Santo Domingo Las Americas

Tue 8/26

5:05 pm-9:17 am

2 stops19h 12m

$359

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Tue 9/2

10:31 pm-4:00 pm

2 stops14h 29m

Santo Domingo Las Americas

Wed 9/10

5:05 pm-4:29 pm

2 stops26h 24m

$366

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Sat 8/9

9:28 pm-12:32 am

1 stop24h 04m

Santo Domingo Las Americas

Thu 8/21

1:53 pm-8:08 am

2 stops45h 15m

$451

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Thu 10/2

12:06 pm-10:56 am

1 stop19h 50m

Santo Domingo Las Americas

Wed 10/8

6:24 pm-12:30 pm

1 stop21h 06m

$459

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Tue 9/2

10:15 pm-1:24 pm

1 stop12h 09m

Santo Domingo Las Americas

Mon 9/15

2:54 pm-11:13 pm

1 stop11h 19m

$467

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Thu 8/21

12:20 pm-9:25 am

1 stop18h 05m

Santo Domingo Las Americas

Mon 8/25

7:05 am-11:08 pm

1 stop19h 03m

$471

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Mon 8/11

1:57 pm-3:47 pm

2 stops22h 50m

$173

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Tue 8/26

5:07 pm-4:00 pm

2 stops19h 53m

$184

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Sat 8/16

1:57 pm-10:45 am

1 stop17h 48m

$188

Los AngelesSanto Domingo

LAX - SDQ

LAXSDQ

Los Angeles

Sat 9/6

12:05 pm-10:58 am

1 stop19h 53m

$221

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 14 results

Best time to book a flight from Irvine to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Irvine with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santo Domingo

How far ahead should I book a flight from Irvine to Santo Domingo?

The best time to book flights from Irvine to Santo Domingo is 62 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Irvine to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Irvine to Santo Domingo (average of $362). Flying from Irvine to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to SDQ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Santo Domingo as you normally would.

Reviews of airlines servicing Santo Domingo

See what other customers who have flown with Delta, Copa Airlines, and JetBlue from Irvine to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,983 reviews

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines

7.5

Good

1,493 reviews

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

JetBlue

7.3

Good

2,915 reviews

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Avianca

6.7

Okay

2,388 reviews

Delta

8.0

Very good

7,983 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airport do you fly into for flights to Santo Domingo from Irvine?
Located just 17.5 mi from the city center, Santo Domingo Las Americas is the airport most travelers will use when flying to Santo Domingo from Irvine. Booking flights from Irvine to Las Americas (SDQ) should be relatively easy as there are 0 daily inbound flights from Irvine from 6 different airlines.
What are the cheapest airlines to fly from Irvine to Santo Domingo one-way?
The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $184. However, be on the lookout for offers from Frontier and Copa Airlines, as they are both options that can get you from Irvine to Santo Domingo for a low price.
Can I find deals for flights from Irvine to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Irvine to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Irvine to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santo Domingo.
Can I find deals for business class flights from Irvine to Santo Domingo?
Yes. Cheapflights offers flight deals from Irvine to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Irvine to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Irvine to Santo Domingo (average of $362). Flying from Irvine to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Irvine to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$427	Average$524	FlexibilityNo cancel fee	On-time69%
JetBlue	Cheapest$449	Average$607	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$459	Average$600	FlexibilityNo cancel fee	On-time71%
Spirit Airlines	Cheapest$461	Average$623	FlexibilityNo cancel fee	On-time65%
Delta	Cheapest$470	Average$610	FlexibilityNo cancel fee	On-timeN/A
Copa Airlines	Cheapest$472	Average$729	FlexibilityNo cancel fee	On-time70%

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$173+ Cheap flights from Irvine, CA to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Irvine to Santo Domingo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Irvine to Santo Domingo Las Americas are usually found in September or May, booked 62 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Irvine to Santo Domingo

Keep the following information in mind while searching for Irvine to Santo Domingo flight deals. Data was last updated August 2, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Irvine to Santo Domingo

Cheapest flights from Irvine to Santo DomingoExplore the most affordable flight options available from Irvine to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2025.

Explore the most affordable flight options available from Irvine to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Irvine to Santo Domingo that are best for you.

Best time to book a flight from Irvine to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Irvine with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santo Domingo

How far ahead should I book a flight from Irvine to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Santo Domingo. Price data was last updated on July 25, 2025.

What is the cheapest month to book a flight from Irvine to Santo Domingo?

What is the cheapest time of day to fly from IR9 to SDQ?

Find hourly flight availability from Irvine to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 2, 2025.

Reviews of airlines servicing Santo Domingo

See what other customers who have flown with Delta, Copa Airlines, and JetBlue from Irvine to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santo Domingo from Irvine?

What are the cheapest airlines to fly from Irvine to Santo Domingo one-way?

Can I find deals for flights from Irvine to Santo Domingo that include hotel bookings?

How can I find direct flights from Irvine to Santo Domingo?

Can I find deals for business class flights from Irvine to Santo Domingo?

What is the cheapest month to book a flight from Irvine to Santo Domingo?

Traveling to a place near Santo Domingo?

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Alternative routes for Irvine to Santo Domingo

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Top 6 airlines flying from Irvine to Santo Domingo

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Cheapest flights from Irvine to Santo Domingo
Explore the most affordable flight options available from Irvine to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2025.