How long is the flight from Greenville to Santo Domingo?

Airlines like American Airlines and Delta fly from Greenville to Santo Domingo in about 6h. The time it takes to get you to your destination can typically vary by up to 31m. There are 1373 mi between Greenville and Santo Domingo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Greenville to Santo Domingo round-trip?

Our cheapest airline available from Greenville to Santo Domingo is Delta. Our recent data shows that you can find tickets from as low as $484 on this airline. An additional option worth looking into is American Airlines, starting at $511. Delta is priced at 22% lower than the current average price of a flight leaving 3 months from now.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What is the cheapest time of day to fly from GSP to SDQ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Greenville to Santo Domingo as you normally would.

Most accurate provider : When it comes to deals on Greenville-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Greenville-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Greenville-Santo Domingo flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Greenville-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Greenville to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Greenville to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Greenville to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Santo Domingo.

Can I find deals for business class flights from Greenville to Santo Domingo?

Yes. Cheapflights offers flight deals from Greenville to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$171+ Flights from Greenville to Santo Domingo

Q: How much does it cost to fly round-trip from Greenville to Santo Domingo?

Airfare is below average for this route at the moment. Greenville to Santo Domingo flights typically cost between $779 and $1,116 in January. The cheapest round-trip price found within the last 3 days was $468 on Delta (Jan 21-Jan 29).

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Cheap flight deals from Greenville to Santo Domingo

Cheapest flights from Greenville to Santo Domingo
Explore the most affordable flight options available from Greenville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

Wed 12/317:45 amGSP - SDQ

1 stop13h 15mAmerican Airlines

Sun 1/44:49 pmSDQ - GSP

1 stop9h 02mAmerican Airlines

Deal found 12/12

$1,289

Wed 12/3112:43 pmGSP - SDQ

2 stops13h 26mDelta

Sun 1/46:50 amSDQ - GSP

2 stops13h 23mDelta

Deal found 12/14

$1,826

Best flights from Greenville to Santo Domingo
Discover carefully curated flight deals from Greenville to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 15, 2025.

Wed 1/217:00 amGSP - SDQ

1 stop6h 00mAmerican Airlines

Thu 1/296:29 pmSDQ - GSP

1 stop6h 28mAmerican Airlines

Deal found 12/13

$468

Wed 1/216:50 amGSP - SDQ

1 stop6h 31mDelta

Thu 1/293:46 pmSDQ - GSP

1 stop7h 06mDelta

Deal found 12/15

$468

Sun 2/16:20 amGSP - SDQ

1 stop7h 46mUnited Airlines

Thu 2/54:18 pmSDQ - GSP

1 stop8h 30mUnited Airlines

Deal found 12/12

$628

Sun 1/116:00 amGSP - SDQ

1 stop16h 26mAmerican Airlines

Sun 1/186:29 pmSDQ - GSP

1 stop6h 28mAmerican Airlines

Deal found 12/12

$508

Mon 1/55:39 amGSP - SDQ

1 stop15h 21mAmerican Airlines

Mon 1/127:00 amSDQ - GSP

1 stop14h 59mAmerican Airlines

Deal found 12/13

$528

Last-minute flights from Greenville to Santo Domingo
Discover last-minute flight deals from Greenville to Santo Domingo. Data last updated December 15, 2025 and is based on user searches.

Wed 12/317:45 amGSP - SDQ

1 stop13h 15mAmerican Airlines

Sun 1/44:49 pmSDQ - GSP

1 stop9h 02mAmerican Airlines

Deal found 12/12

$1,289

Mon 1/55:39 amGSP - SDQ

1 stop15h 21mAmerican Airlines

Mon 1/127:00 amSDQ - GSP

1 stop14h 59mAmerican Airlines

Deal found 12/13

$528

Sun 1/116:00 amGSP - SDQ

1 stop16h 26mAmerican Airlines

Sun 1/186:29 pmSDQ - GSP

1 stop6h 28mAmerican Airlines

Deal found 12/12

$508

Wed 1/216:50 amGSP - SDQ

1 stop6h 31mDelta

Thu 1/293:46 pmSDQ - GSP

1 stop7h 06mDelta

Deal found 12/15

$468

One-way flights from Greenville to Santo Domingo
Search for one-way flight options from Greenville to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated December 15, 2025.

Sun 2/15:45 pmGSP - SDQ

1 stop19h 42mMultiple Airlines

Deal found 12/13

$171

Fri 2/69:48 amGSP - SDQ

1 stop27h 39mMultiple Airlines

Deal found 12/13

$187

Mon 2/24:39 pmGSP - SDQ

2 stops46h 47mMultiple Airlines

Deal found 12/13

$202

Thu 2/55:45 pmGSP - SDQ

3 stops21h 41mMultiple Airlines

Deal found 12/13

$259

Wed 2/46:50 amGSP - SDQ

2 stops11h 24mDelta

Deal found 12/13

$282

Sat 2/712:00 pmGSP - SDQ

2 stops11h 30mDelta

Deal found 12/13

$287

Fri 3/138:18 pmGSP - SDQ

2 stops33h 13mMultiple Airlines

Deal found 12/13

$296

Find flight deals from Greenville to Santo Domingo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$468 (Delta)
One-way from	$171 (Kiwi.com)
Popular in	December
Cheapest in	May
Average price	$921

Provider with most accurate pricing for Greenville-Santo Domingo Las Americas flight deals.

Search Deals

Provider most trusted by Cheapflights users for Greenville-Santo Domingo Las Americas flights.

Search Deals

From Greenville to Santo Domingo Las Americas

Search Deals

One-way flight from Greenville to Santo Domingo Las Americas

Search Deals

Highest demand for flights based on searches. 3% potential increase in price ($23 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($27 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Greenville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 1/21

7:00 am-2:00 pm

1 stop6h 00m

Santo Domingo Las Americas

Thu 1/29

6:29 pm-11:57 pm

1 stop6h 28m

$468

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 1/21

6:50 am-2:21 pm

1 stop6h 31m

Santo Domingo Las Americas

Thu 1/29

3:46 pm-9:52 pm

1 stop7h 06m

$468

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sun 1/11

6:00 am-11:26 pm

1 stop16h 26m

Santo Domingo Las Americas

Sun 1/18

6:29 pm-11:57 pm

1 stop6h 28m

$508

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Mon 1/5

5:39 am-10:00 pm

1 stop15h 21m

Santo Domingo Las Americas

Mon 1/12

7:00 am-8:59 pm

1 stop14h 59m

$528

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sun 2/1

6:20 am-3:06 pm

1 stop7h 46m

Santo Domingo Las Americas

Thu 2/5

4:18 pm-11:48 pm

1 stop8h 30m

$628

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Mon 2/2

9:48 am-2:27 pm

1 stop27h 39m

$171

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sun 2/1

5:45 pm-2:27 pm

1 stop19h 42m

$171

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Wed 2/4

6:50 am-7:14 pm

2 stops11h 24m

$282

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Thu 2/5

5:40 am-7:14 pm

2 stops12h 34m

$287

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

Sat 2/7

6:50 am-2:21 pm

1 stop6h 31m

$287

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 11 results

Compare providers for flights from Greenville to Santo Domingo

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santo Domingo in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Ovago	Price Accuracy2 stars	Trust Score*2 stars
AranGrant	Price Accuracy2 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Greenville-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Greenville-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Greenville-Santo Domingo flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Greenville-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Greenville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Santo Domingo

What is the cheapest month to book a flight from Greenville to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Greenville to Santo Domingo (average of $224). Flying from Greenville to Santo Domingo in December is currently the most expensive (average of $365). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Greenville to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Read through reviews of airlines operating flights from Greenville to Santo Domingo, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,008 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,008 reviews

Delta

7.9

Good

8,008 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,051 reviews

Delta

7.9

Good

8,008 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Greenville to Santo Domingo?
Airlines like American Airlines and Delta fly from Greenville to Santo Domingo in about 6h. The time it takes to get you to your destination can typically vary by up to 31m. There are 1373 mi between Greenville and Santo Domingo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from Greenville to Santo Domingo round-trip?
Our cheapest airline available from Greenville to Santo Domingo is Delta. Our recent data shows that you can find tickets from as low as $484 on this airline. An additional option worth looking into is American Airlines, starting at $511. Delta is priced at 22% lower than the current average price of a flight leaving 3 months from now.
Can I find deals for flights from Greenville to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Greenville to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Greenville to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Santo Domingo.
Can I find deals for business class flights from Greenville to Santo Domingo?
Yes. Cheapflights offers flight deals from Greenville to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Greenville to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Greenville to Santo Domingo (average of $224). Flying from Greenville to Santo Domingo in December is currently the most expensive (average of $365). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Greenville to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$484	Average$513	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$511	Average$567	FlexibilityNo cancel fee	On-time71%

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$171+ Cheap flights from Greenville (GSP) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Greenville to Santo Domingo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Greenville to Santo Domingo

Cheapest flights from Greenville to Santo DomingoExplore the most affordable flight options available from Greenville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

Explore the most affordable flight options available from Greenville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

Find flight deals from Greenville to Santo Domingo

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Greenville to Santo Domingo that are best for you.

Compare providers for flights from Greenville to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santo Domingo in December.

Best time to book a flight from Greenville to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Greenville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Santo Domingo

What is the cheapest month to book a flight from Greenville to Santo Domingo?

How much does it cost to fly round-trip from Greenville to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Read through reviews of airlines operating flights from Greenville to Santo Domingo, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Greenville to Santo Domingo?

What are the cheapest airlines flying from Greenville to Santo Domingo round-trip?

Can I find deals for flights from Greenville to Santo Domingo that include hotel bookings?

How can I find direct flights from Greenville to Santo Domingo?

Can I find deals for business class flights from Greenville to Santo Domingo?

What is the cheapest month to book a flight from Greenville to Santo Domingo?

Traveling to a place near Santo Domingo?

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Alternative routes for Greenville to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Greenville to Santo Domingo

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Cheapest flights from Greenville to Santo Domingo
Explore the most affordable flight options available from Greenville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.