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Santo Domingo

$422+ Cheap flights from Greenville (GSP) to Santo Domingo (SDQ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SDQ
nov. 28 — dic. 51
vie. 11/28
vie. 12/5
1 adult, Economy
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Cheap flight deals from Greenville to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated octubre 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$422
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$602
Provider with most accurate pricing for Greenville-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Greenville-Santo Domingo Las Americas flights.
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From Greenville to Santo Domingo Las Americas
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Highest demand for flights based on searches. 6% potential increase in price ($41 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Greenville to Santo Domingo

Cheapest flights from Greenville to Santo Domingo
Explore the most affordable flight options available from Greenville to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/2511:33 amGSP - SDQ
1 stop14h 59mMultiple Airlines
mar. 12/303:59 amSDQ - GSP
1 stop12h 56mMultiple Airlines
Deal found 10/27$422
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/2511:33 amGSP - SDQ
1 stop14h 59mMultiple Airlines
lun. 1/128:01 amSDQ - GSP
1 stop8h 58mMultiple Airlines
Deal found 10/27$447
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/244:40 pmGSP - SDQ
1 stop21h 43mMultiple Airlines
mar. 12/303:59 amSDQ - GSP
1 stop12h 56mMultiple Airlines
Deal found 10/27$466
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/2511:34 amGSP - SDQ
1 stop11h 11mAmerican Airlines
mar. 12/24:45 pmSDQ - GSP
1 stop8h 14mAmerican Airlines
Deal found 10/26$468
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/244:40 pmGSP - SDQ
1 stop21h 43mMultiple Airlines
lun. 12/2912:35 pmSDQ - GSP
1 stop7h 48mMultiple Airlines
Deal found 10/28$476
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/2511:33 amGSP - SDQ
1 stop14h 59mMultiple Airlines
dom. 1/118:01 amSDQ - GSP
1 stop9h 18mMultiple Airlines
Deal found 10/27$480
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/233:26 pmGSP - SDQ
1 stop11h 06mMultiple Airlines
mar. 12/303:59 amSDQ - GSP
1 stop12h 56mMultiple Airlines
Deal found 10/27$484
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/244:40 pmGSP - SDQ
1 stop21h 43mMultiple Airlines
lun. 1/128:01 amSDQ - GSP
1 stop8h 58mMultiple Airlines
Deal found 10/27$494

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
Use the filters below to find and compare flights from Greenville to Santo Domingo that are best for you.

Fly from

Greenville

Fly to

Santo Domingo

Route

Depart

Return

Price

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

mar. 11/25

11:34 am-11:45 pm

1 stop11h 11m

Santo Domingo Las Americas

mar. 12/2

4:45 pm-11:59 pm

1 stop8h 14m

$468

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

jue. 1/22

7:00 am-10:39 pm

1 stop14h 39m

Santo Domingo Las Americas

lun. 1/26

3:00 pm-11:57 pm

1 stop9h 57m

$488

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

sáb. 11/15

6:11 pm-2:05 pm

1 stop18h 54m

Santo Domingo Las Americas

mar. 12/9

3:06 pm-11:59 pm

1 stop9h 53m

$504

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

mié. 12/24

4:40 pm-3:32 am

2 stops33h 52m

Santo Domingo Las Americas

lun. 12/29

12:35 pm-7:23 pm

1 stop7h 48m

$507

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

mié. 11/12

6:01 am-3:45 pm

2 stops8h 44m

Santo Domingo Las Americas

mar. 12/9

6:00 am-3:10 pm

2 stops10h 10m

$508

GreenvilleSanto Domingo

GSP - SDQ

GSPSDQ

Greenville

vie. 11/28

11:34 am-11:45 pm

1 stop11h 11m

Santo Domingo Las Americas

mar. 12/2

1:25 pm-11:59 pm

1 stop11h 34m

$543

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Compare providers for flights from Greenville to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Santo Domingo in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Greenville-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Greenville-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Santo Domingo

What is the cheapest month to book a flight from Greenville to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Greenville to Santo Domingo (average of $226). Flying from Greenville to Santo Domingo in December is currently the most expensive (average of $400). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated octubre 29, 2025.
Read through reviews of airlines operating flights from Greenville to Santo Domingo, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Crew

8.5

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Santo Domingo?

    Airlines like American Airlines fly from Greenville to Santo Domingo in about 11h 11m. The time it takes to get you to your destination can typically vary by up to . There are 1373 mi between Greenville and Santo Domingo.

  • What are the cheapest airlines flying from Greenville to Santo Domingo round-trip?

    Our cheapest airline available from Greenville to Santo Domingo is Delta. Our recent data shows that you can find tickets from as low as $484 on this airline. An additional option worth looking into is American Airlines, starting at $499. Delta is priced at 24% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Greenville to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Greenville to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Santo Domingo.

  • Can I find deals for business class flights from Greenville to Santo Domingo?

    Yes. Cheapflights offers flight deals from Greenville to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Greenville to Santo Domingo (average of $226). Flying from Greenville to Santo Domingo in December is currently the most expensive (average of $400). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 2 airlines flying from Greenville to Santo Domingo

Discover the top 2 airlines that operate flights from Greenville to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$484Average$484FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$499Average$598FlexibilityNo cancel feeOn-time71%

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