HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santo Domingo

$147+ Cheap flights from Durham, NC to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/23. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SDQ
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Durham to Santo Domingo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Durham to Santo Domingo Las Americas are usually found in October or September, booked 43 days in advance, depart on a Wednesday or Tuesday and return on a Monday

Find flight deals from Durham to Santo Domingo

Cheapest flights from Durham to Santo Domingo
Explore the most affordable flight options available from Durham to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:16 pmRDU - SDQ
2 stops18h 03mAmerican Airlines
Thu 1/224:47 pmSDQ - RDU
1 stop8h 12mAmerican Airlines
Deal found 10/28$322
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amRDU - SDQ
1 stop15h 00mAmerican Airlines
Thu 1/221:23 pmSDQ - RDU
1 stop9h 14mAmerican Airlines
Deal found 10/30$324
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/125:39 amRDU - SDQ
2 stops10h 35mAmerican Airlines
Thu 1/226:29 pmSDQ - RDU
1 stop6h 30mAmerican Airlines
Deal found 10/29$328
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:01 pmRDU - SDQ
1 stop18h 04mAmerican Airlines
Wed 11/126:14 pmSDQ - RDU
2 stops14h 49mAmerican Airlines
Deal found 10/27$330
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:18 amRDU - SDQ
1 stop7h 23mDelta
Fri 10/316:05 amSDQ - RDU
1 stop8h 05mDelta
Deal found 10/28$331
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:18 amRDU - SDQ
1 stop7h 23mDelta
Sat 11/16:05 amSDQ - RDU
1 stop8h 05mDelta
Deal found 10/28$332
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/123:14 pmRDU - SDQ
1 stop10h 12mCopa Airlines
Tue 1/277:05 pmSDQ - RDU
1 stop19h 10mCopa Airlines
Deal found 10/29$333
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/301:08 pmRDU - SDQ
2 stops11h 19mDelta
Mon 11/38:49 pmSDQ - RDU
1 stop14h 49mDelta
Deal found 10/28$334
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2711:11 amRDU - SDQ
2 stops24h 04mAmerican Airlines
Thu 12/46:00 amSDQ - RDU
2 stops10h 27mAmerican Airlines
Deal found 10/28$335

Cheap flight deals from Durham to Santo Domingo

Keep the following information in mind while searching for Durham to Santo Domingo flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$322
(American Airlines)

One-way from

$147
(JetBlue)

Popular in

December

Cheapest in

October

Average price

$442
Provider with most accurate pricing for Raleigh-Durham-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Santo Domingo Las Americas flights.
Search Deals
From Durham to Santo Domingo Las Americas
Search Deals
One-way flight from Durham to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($64 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Durham to Santo Domingo that are best for you.

Fly from

Durham

Fly to

Santo Domingo

Route

Depart

Return

Price

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Thu 11/13

2:47 pm-1:36 am

1 stop9h 49m

Santo Domingo Las Americas

Mon 11/17

8:40 pm-9:55 am

1 stop14h 15m

$328

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Sat 11/15

7:01 pm-3:45 pm

1 stop19h 44m

Santo Domingo Las Americas

Fri 1/23

3:00 pm-10:58 pm

2 stops8h 58m

$328

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Tue 1/27

7:15 pm-12:21 pm

1 stop16h 06m

Santo Domingo Las Americas

Sun 2/1

6:29 pm-10:58 am

1 stop17h 29m

$330

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Mon 11/10

7:01 pm-2:05 pm

1 stop18h 04m

Santo Domingo Las Americas

Wed 11/12

6:14 pm-8:03 am

2 stops14h 49m

$330

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Thu 11/27

11:11 am-12:15 pm

2 stops24h 04m

Santo Domingo Las Americas

Thu 12/4

6:00 am-5:41 pm

2 stops12h 41m

$335

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Mon 12/1

9:37 pm-9:45 pm

1 stop23h 08m

Santo Domingo Las Americas

Wed 12/10

4:21 pm-11:49 am

2 stops20h 28m

$347

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Wed 12/3

8:39 pm-3:23 pm

1 stop17h 44m

Santo Domingo Las Americas

Wed 12/10

4:21 pm-4:55 pm

1 stop25h 34m

$358

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Mon 11/17

7:15 am-2:17 pm

1 stop6h 02m

Santo Domingo Las Americas

Tue 11/18

4:10 am-4:15 pm

1 stop13h 05m

$361

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Tue 12/2

5:39 pm-5:25 am

1 stop10h 46m

Santo Domingo Las Americas

Wed 12/10

4:21 pm-4:55 pm

1 stop25h 34m

$370

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Sun 11/23

6:09 am-2:17 pm

1 stop7h 08m

$147

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 17 results
1
2

Best time to book a flight from Durham to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santo Domingo

How far ahead should I book a flight from Durham to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Santo Domingo. Price data was last updated on October 24, 2025.

The best time to book flights from Durham to Santo Domingo is 43 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Durham to Santo Domingo?

Currently, October is the cheapest month in which you can book a flight from Durham to Santo Domingo (average of $147). Flying from Durham to Santo Domingo in December is currently the most expensive (average of $389). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SDQ?

Find hourly flight availability from Durham to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

A simple way to save on the total cost of your ticket is to fly from Durham to Santo Domingo in the afternoon. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Durham to Santo Domingo?

Use this chart to determine the cheapest time to fly round-trip from Durham to Santo Domingo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Durham to Santo Domingo flight should consider departing on Tuesday evenings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from Durham to Santo Domingo, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,993 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,993 reviews
Delta
7.9
Good
7,993 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,998 reviews
Delta
7.9
Good
7,993 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,030 reviews
Delta
7.9
Good
7,993 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
JetBlue
7.2
Good
2,906 reviews
Delta
7.9
Good
7,993 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Frontier
5.8
Fair
3,123 reviews
Delta
7.9
Good
7,993 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Durham to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santo Domingo from Durham?

    Located just 17.5 mi from the city center, Santo Domingo Las Americas is the airport most travelers will use when flying to Santo Domingo from Durham. Booking flights from Durham to Las Americas (SDQ) should be relatively easy as there are 0 daily inbound flights from Durham from 5 different airlines.

  • How long is the flight from Durham to Santo Domingo?

    There are many flights that can get you from Durham to Santo Domingo in 9h 49m. Fly via Delta or American Airlines to get the fastest option. There are 1327 mi between Durham and Santo Domingo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Durham to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Durham to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santo Domingo.

  • Can I find deals for business class flights from Durham to Santo Domingo?

    Yes. Cheapflights offers flight deals from Durham to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Santo Domingo?

    Currently, October is the cheapest month in which you can book a flight from Durham to Santo Domingo (average of $147). Flying from Durham to Santo Domingo in December is currently the most expensive (average of $389). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Durham to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Punta Cana flights
Raleigh to Punta Cana flights
Charlotte to Santo Domingo flights
Raleigh to Santo Domingo flights
Norfolk to Punta Cana flights
Charlotte to Puerto Plata flights
Greensboro to Punta Cana flights
Raleigh to Santiago de los Caballeros flights
Myrtle Beach to Punta Cana flights
Wilmington to Punta Cana flights
Raleigh to Puerto Plata flights
Norfolk to Puerto Plata flights
Charlotte to Santiago de los Caballeros flights
Greensboro to Santo Domingo flights
Greensboro to Santiago de los Caballeros flights
Knoxville to Punta Cana flights
Asheville to Punta Cana flights
Norfolk to Santo Domingo flights
Asheville to Santo Domingo flights
Blountville to Punta Cana flights
Norfolk to Santiago de los Caballeros flights
Wilmington to Santo Domingo flights
Myrtle Beach to Santo Domingo flights
Fayetteville to Punta Cana flights
Greensboro to Puerto Plata flights
Wilmington to Puerto Plata flights
Fayetteville to Puerto Plata flights
Jacksonville to Santiago de los Caballeros flights
Fayetteville to Santiago de los Caballeros flights
Myrtle Beach to Puerto Plata flights
Charlotte to Nagua flights
Knoxville to Puerto Plata flights

Top 5 airlines flying from Durham to Santo Domingo

Discover the top 5 airlines that operate flights from Durham to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$244Average$339FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$317Average$578FlexibilityNo cancel feeOn-time69%
DeltaCheapest$319Average$530FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$348Average$531FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$352Average$576FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.