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Santo Domingo

$125+ Cheap flights from Durham, NC to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/24. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — SDQ
ene. 15 — ene. 221
jue. 1/15
jue. 1/22
1 adult, Economy
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Cheapflights Tip: The best prices from Durham to Santo Domingo Las Americas are usually found in October or September, booked 36 days in advance, depart on a Wednesday or Tuesday and return on a Monday

Cheap flight deals from Durham to Santo Domingo

Cheapest flights from Durham to Santo Domingo
Explore the most affordable flight options available from Durham to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

This Frontier deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/306:00 amRDU - SDQ
1 stop8h 19mFrontier
jue. 1/154:24 pmSDQ - RDU
2 stops15h 55mFrontier
Deal found 12/14$336
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/306:00 amRDU - SDQ
1 stop15h 00mAmerican Airlines
jue. 1/226:00 amSDQ - RDU
1 stop18h 59mAmerican Airlines
Deal found 12/15$394
This Frontier deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/278:14 pmRDU - SDQ
2 stops18h 04mFrontier
jue. 1/112:25 pmSDQ - RDU
1 stop9h 27mFrontier
Deal found 12/14$403
This Expedia deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/241:05 pmRDU - SDQ
1 stop25h 19mFrontier
jue. 1/112:25 pmSDQ - RDU
1 stop9h 27mFrontier
Deal found 12/14$417
This Expedia deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/269:47 pmRDU - SDQ
1 stop12h 23mFrontier
jue. 1/112:25 pmSDQ - RDU
1 stop9h 27mFrontier
Deal found 12/14$429
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/315:11 pmRDU - SDQ
1 stop15h 56mAmerican Airlines
mié. 1/147:00 amSDQ - RDU
1 stop14h 22mAmerican Airlines
Deal found 12/15$438

Find flight deals from Durham to Santo Domingo

Keep the following information in mind while searching for Durham to Santo Domingo flight deals. Data was last updated diciembre 16, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$324
(JetBlue)

One-way from

$125
(Frontier)

Popular in

December

Cheapest in

October

Average price

$661
Provider with most accurate pricing for Raleigh-Durham-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Raleigh-Durham-Santo Domingo Las Americas flights.
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From Durham to Santo Domingo Las Americas
Search Deals
One-way flight from Durham to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($71 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
Use the filters below to find and compare flights from Durham to Santo Domingo that are best for you.

Fly from

Durham

Fly to

Santo Domingo

Route

Depart

Return

Price

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

lun. 2/2

7:00 am-2:14 pm

1 stop6h 14m

Santo Domingo Las Americas

jue. 2/5

3:30 pm-11:08 pm

1 stop8h 38m

$324

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

jue. 1/22

12:24 pm-10:39 pm

2 stops9h 15m

Santo Domingo Las Americas

mié. 1/28

6:00 am-5:24 pm

2 stops12h 24m

$328

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

jue. 1/22

12:24 pm-10:39 pm

2 stops9h 15m

Santo Domingo Las Americas

mar. 1/27

6:00 am-5:24 pm

2 stops12h 24m

$328

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

mié. 2/18

5:54 pm-11:26 am

1 stop16h 32m

Santo Domingo Las Americas

dom. 2/22

12:35 pm-10:14 pm

1 stop10h 39m

$336

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

jue. 1/15

6:10 am-3:27 pm

1 stop8h 17m

Santo Domingo Las Americas

lun. 1/19

12:15 pm-12:33 pm

1 stop25h 18m

$343

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

vie. 2/27

3:46 pm-2:55 am

1 stop10h 09m

Santo Domingo Las Americas

mar. 3/3

3:28 pm-10:10 pm

1 stop7h 42m

$348

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

mié. 2/25

3:46 pm-1:58 am

1 stop9h 12m

Santo Domingo Las Americas

mar. 3/3

3:28 pm-10:10 pm

1 stop7h 42m

$348

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

jue. 2/26

3:46 pm-1:58 am

1 stop9h 12m

Santo Domingo Las Americas

mar. 3/3

3:28 pm-10:10 pm

1 stop7h 42m

$348

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

vie. 2/27

3:46 pm-1:58 am

1 stop9h 12m

Santo Domingo Las Americas

lun. 3/2

6:20 am-2:46 pm

1 stop9h 26m

$354

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

mar. 1/27

12:03 pm-6:44 pm

1 stop5h 41m

Santo Domingo Las Americas

dom. 2/1

5:20 am-1:44 pm

1 stop9h 24m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 20 results
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Best time to book a flight from Durham to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santo Domingo

How far ahead should I book a flight from Durham to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Santo Domingo. Price data was last updated on December 12, 2025.

The best time to book flights from Durham to Santo Domingo is 36 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Durham to Santo Domingo?

Currently, October is the cheapest month in which you can book a flight from Durham to Santo Domingo (average of $146). Flying from Durham to Santo Domingo in March is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SDQ?

Find hourly flight availability from Durham to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 16, 2025.

A simple way to save on the total cost of your ticket is to fly from Durham to Santo Domingo in the afternoon. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Durham to Santo Domingo?

Use this chart to determine the cheapest time to fly round-trip from Durham to Santo Domingo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Durham to Santo Domingo flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Durham to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated diciembre 16, 2025.
Read through reviews of airlines operating flights from Durham to Santo Domingo, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Food

7.3

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,092 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,049 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
JetBlue
7.2
Good
2,895 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Frontier
5.8
Fair
3,082 reviews
Delta
7.9
Good
8,008 reviews

Food

7.3

Comfort

7.9

Boarding

8.1

Overall

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Durham to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santo Domingo from Durham?

    Located just 17.5 mi from the city center, Santo Domingo Las Americas is the airport most travelers will use when flying to Santo Domingo from Durham. Booking flights from Durham to Las Americas (SDQ) should be relatively easy as there are 0 daily inbound flights from Durham from 5 different airlines.

  • How long is the flight from Durham to Santo Domingo?

    There are many flights that can get you from Durham to Santo Domingo in 6h 14m. Fly via JetBlue, American Airlines, or Frontier to get the fastest option. There are 1327 mi between Durham and Santo Domingo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Durham to Santo Domingo one-way?

    The cheapest airlines for a one-way flight from Durham to Santo Domingo are Frontier ($144), United Airlines ($145), and American Airlines ($148).

  • Can I find deals for flights from Durham to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Durham to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santo Domingo.

  • Can I find deals for business class flights from Durham to Santo Domingo?

    Yes. Cheapflights offers flight deals from Durham to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Santo Domingo?

    Currently, October is the cheapest month in which you can book a flight from Durham to Santo Domingo (average of $146). Flying from Durham to Santo Domingo in March is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Durham to Santo Domingo

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Top 5 airlines flying from Durham to Santo Domingo

Discover the top 5 airlines that operate flights from Durham to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$244Average$339FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$317Average$526FlexibilityNo cancel feeOn-time69%
DeltaCheapest$319Average$485FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$344Average$569FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$348Average$522FlexibilityNo cancel feeOn-time62%

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