What are the cheapest airlines to fly from Durham to Santo Domingo one-way?

The cheapest airlines for a one-way flight from Durham to Santo Domingo are Spirit Airlines ($125), Frontier ($138), and JetBlue ($205).

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What are the most popular airlines that fly from Durham to Santo Domingo?

Consider American Airlines, JetBlue or Copa Airlines when booking your flight. These represent the most popular airlines when flying from Durham to Santo Domingo.

How far in advance should I book a flight from Durham to Santo Domingo?

Users have found that booking a flight from Durham to Santo Domingo at least 59 days early can save you up to 40% on average compared to booking a flight this week. If booking 59 days before your flight isn’t an option for you, users have found flights from Durham to Santo Domingo for as little as $438 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $438 for flights departing within the next 3 days.

What is the cheapest month to fly from Durham to Santo Domingo?

September is one of the best times of the year to fly to Santo Domingo from Durham. Prices for September average $519 per person but you can even find prices for as low as $352. The most expensive prices can be found in the month of December. Opting for a September flight can save you 37% on your journey compared to booking in December

What airport do you fly into for flights to Santo Domingo from Durham?

Located just 17.5 mi from the city center, Santo Domingo Las Americas is the airport most travelers will use when flying to Santo Domingo from Durham. Booking flights from Durham to Las Americas (SDQ) should be relatively easy as there are 0 daily inbound flights from Durham from 6 different airlines.

Can I find deals for flights from Durham to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Durham to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Durham to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santo Domingo.

Can I find deals for business class flights from Durham to Santo Domingo?

Yes. Cheapflights offers flight deals from Durham to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$125+ Flights from Durham to Santo Domingo

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Durham to Santo Domingo Las Americas are usually found in September or February, booked 58 days in advance, depart on a Wednesday or Tuesday and return on a Monday

Cheap flight deals from Durham to Santo Domingo

Round-trip from	$304 (CheapOair)
One-way from	$125 (Cheapflightsfares)
Popular in	December
Cheapest in	September
Average price	$614

From Durham to Santo Domingo Las Americas

Search Deals

One-way flight from Durham to Santo Domingo Las Americas

Search Deals

Highest demand for flights based on searches. 8% potential increase in price ($47 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in July 2025

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Find flight deals from Durham to Santo Domingo

Cheapest flights from Durham to Santo Domingo
Explore the most affordable flight options available from Durham to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Thu 9/119:23 amRDU - SDQ

1 stop6h 37mSpirit Airlines

Wed 9/175:05 pmSDQ - RDU

1 stop21h 30mSpirit Airlines

Deal found 7/31

$296

Thu 8/145:15 pmRDU - SDQ

1 stop7h 17mFrontier

Mon 8/1810:17 amSDQ - RDU

1 stop7h 11mFrontier

Deal found 7/30

$313

Mon 8/47:53 pmRDU - SDQ

1 stop15h 56mMultiple Airlines

Wed 8/135:05 pmSDQ - RDU

1 stop25h 46mMultiple Airlines

Deal found 7/31

$339

Wed 10/18:00 amRDU - SDQ

1 stop5h 24mJetBlue

Thu 10/92:34 pmSDQ - RDU

1 stop7h 36mJetBlue

Deal found 7/31

$393

Sat 9/1311:20 amRDU - SDQ

1 stop13h 16mDelta

Wed 9/177:40 pmSDQ - RDU

1 stop12h 09mDelta

Deal found 7/30

$439

Mon 9/18:00 amRDU - SDQ

1 stop12h 30mAmerican Airlines

Sat 9/207:00 amSDQ - RDU

2 stops13h 56mAmerican Airlines

Deal found 7/30

$443

Best flights from Durham to Santo Domingo
Discover carefully curated flight deals from Durham to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 31, 2025.

Thu 9/119:23 amRDU - SDQ

1 stop6h 37mSpirit Airlines

Wed 9/175:05 pmSDQ - RDU

1 stop21h 30mSpirit Airlines

Deal found 7/31

$296

Thu 8/145:15 pmRDU - SDQ

1 stop7h 17mFrontier

Mon 8/1810:17 amSDQ - RDU

1 stop7h 11mFrontier

Deal found 7/30

$313

Mon 8/47:53 pmRDU - SDQ

1 stop15h 56mMultiple Airlines

Wed 8/135:05 pmSDQ - RDU

1 stop25h 46mMultiple Airlines

Deal found 7/30

$339

Wed 10/18:00 amRDU - SDQ

1 stop5h 24mJetBlue

Thu 10/92:34 pmSDQ - RDU

1 stop7h 36mJetBlue

Deal found 7/31

$393

Sat 9/1311:20 amRDU - SDQ

1 stop13h 16mDelta

Wed 9/177:40 pmSDQ - RDU

1 stop12h 09mDelta

Deal found 7/30

$439

Mon 9/16:00 amRDU - SDQ

2 stops9h 25mAmerican Airlines

Sat 9/2012:15 pmSDQ - RDU

2 stops10h 56mAmerican Airlines

Deal found 7/30

$443

Last-minute flights from Durham to Santo Domingo
Discover last-minute flight deals from Durham to Santo Domingo. Data last updated July 31, 2025 and is based on user searches.

Mon 8/47:53 pmRDU - SDQ

1 stop15h 56mMultiple Airlines

Wed 8/135:05 pmSDQ - RDU

1 stop25h 46mMultiple Airlines

Deal found 7/30

$339

Tue 8/56:00 amRDU - SDQ

1 stop9h 20mAmerican Airlines

Wed 8/67:20 pmSDQ - RDU

1 stop15h 56mAmerican Airlines

Deal found 7/31

$459

Thu 8/75:15 pmRDU - SDQ

1 stop7h 17mFrontier

Mon 8/1110:17 amSDQ - RDU

1 stop7h 11mFrontier

Deal found 7/31

$313

Thu 8/78:24 pmRDU - SDQ

2 stops19h 23mMultiple Airlines

Mon 8/1112:46 pmSDQ - RDU

3 stops32h 13mMultiple Airlines

Deal found 7/31

$1,001

Fri 8/85:45 pmRDU - SDQ

1 stop10h 04mJetBlue

Tue 8/1211:05 pmSDQ - RDU

1 stop9h 19mJetBlue

Deal found 7/30

$668

Thu 8/145:15 pmRDU - SDQ

1 stop7h 17mFrontier

Mon 8/1810:17 amSDQ - RDU

1 stop7h 11mFrontier

Deal found 7/30

$313

Fri 8/157:53 pmRDU - SDQ

1 stop13h 32mAmerican Airlines

Mon 8/257:05 amSDQ - RDU

1 stop15h 38mAmerican Airlines

Deal found 7/30

$449

Mon 8/187:56 pmRDU - SDQ

1 stop20h 04mSpirit Airlines

Wed 8/275:05 pmSDQ - RDU

1 stop25h 46mSpirit Airlines

Deal found 7/31

$333

Wed 8/206:45 amRDU - SDQ

1 stop6h 36mJetBlue

Sat 8/302:31 pmSDQ - RDU

1 stop9h 28mJetBlue

Deal found 7/31

$433

Wed 8/274:22 pmRDU - SDQ

1 stop18h 36mCopa Airlines

Sun 8/315:23 amSDQ - RDU

1 stop9h 04mCopa Airlines

Deal found 7/30

$454

Fri 8/297:06 amRDU - SDQ

1 stop10h 54mDelta

Sun 8/312:47 pmSDQ - RDU

1 stop6h 52mDelta

Deal found 7/31

$630

One-way flights from Durham to Santo Domingo
Search for one-way flight options from Durham to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated July 31, 2025.

Thu 9/189:23 amRDU - SDQ

1 stop6h 37mSpirit Airlines

Deal found 7/29

$125

Sun 8/35:15 pmRDU - SDQ

1 stop7h 13mFrontier

Deal found 7/31

$138

Wed 9/177:00 pmRDU - SDQ

1 stop17h 15mMultiple Airlines

Deal found 7/29

$185

Tue 9/98:00 amRDU - SDQ

1 stop5h 24mJetBlue

Deal found 7/30

$205

Wed 9/175:45 amRDU - SDQ

2 stops12h 14mDelta

Deal found 7/30

$208

Tue 8/56:00 amRDU - SDQ

1 stop12h 20mAmerican Airlines

Deal found 7/31

$222

Cheapflights Fare Finder

Use the filters below to find and compare flights from Durham to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Thu 9/11

9:23 am-4:00 pm

1 stop6h 37m

Santo Domingo Las Americas

Wed 9/17

5:05 pm-2:35 pm

1 stop21h 30m

$296

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Thu 8/14

5:15 pm-12:32 am

1 stop7h 17m

Santo Domingo Las Americas

Mon 8/18

10:17 am-5:28 pm

1 stop7h 11m

$313

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Mon 8/4

7:53 pm-11:49 am

1 stop15h 56m

Santo Domingo Las Americas

Wed 8/13

5:05 pm-6:51 pm

1 stop25h 46m

$339

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Wed 10/1

8:00 am-1:24 pm

1 stop5h 24m

Santo Domingo Las Americas

Thu 10/9

2:34 pm-10:10 pm

1 stop7h 36m

$393

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Sat 9/13

11:20 am-12:36 am

1 stop13h 16m

Santo Domingo Las Americas

Wed 9/17

7:40 pm-7:49 am

1 stop12h 09m

$439

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Mon 9/1

6:00 am-3:25 pm

2 stops9h 25m

Santo Domingo Las Americas

Sat 9/20

12:15 pm-11:11 pm

2 stops10h 56m

$443

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Thu 9/18

9:23 am-4:00 pm

1 stop6h 37m

$125

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Sun 8/3

5:15 pm-12:28 am

1 stop7h 13m

$138

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Wed 9/17

7:00 pm-12:15 pm

1 stop17h 15m

$185

RaleighSanto Domingo

RDU - SDQ

RDUSDQ

Raleigh-Durham

Tue 9/9

8:00 am-1:24 pm

1 stop5h 24m

$205

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 12 results

Best time to book a flight from Durham to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Durham with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santo Domingo

How far ahead should I book a flight from Durham to Santo Domingo?

The best time to book flights from Durham to Santo Domingo is 58 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Durham to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Durham to Santo Domingo (average of $362). Flying from Durham to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to SDQ?

When flying from Durham to Santo Domingo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Durham to Santo Domingo?

Travelers seeking maximum savings on their Durham to Santo Domingo flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Santo Domingo

Read through reviews of airlines operating flights from Durham to Santo Domingo, such as Delta, JetBlue, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,981 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

JetBlue

7.3

Good

2,914 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Spirit Airlines

6.3

Okay

8,049 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Frontier

5.9

Fair

3,239 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly into for flights to Santo Domingo from Durham?
Located just 17.5 mi from the city center, Santo Domingo Las Americas is the airport most travelers will use when flying to Santo Domingo from Durham. Booking flights from Durham to Las Americas (SDQ) should be relatively easy as there are 0 daily inbound flights from Durham from 6 different airlines.
What are the cheapest airlines to fly from Durham to Santo Domingo one-way?
The cheapest airlines for a one-way flight from Durham to Santo Domingo are Spirit Airlines ($125), Frontier ($138), and JetBlue ($205).
Can I find deals for flights from Durham to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Durham to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Durham to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Santo Domingo.
Can I find deals for business class flights from Durham to Santo Domingo?
Yes. Cheapflights offers flight deals from Durham to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Durham to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Durham to Santo Domingo (average of $362). Flying from Durham to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Durham to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$258	Average$350	FlexibilityNo cancel fee	On-time62%
Copa Airlines	Cheapest$352	Average$406	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$364	Average$502	FlexibilityNo cancel fee	On-timeN/A
JetBlue	Cheapest$395	Average$537	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$407	Average$596	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$436	Average$591	FlexibilityNo cancel fee	On-time69%

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$125+ Cheap flights from Durham, NC to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Durham to Santo Domingo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Durham to Santo Domingo Las Americas are usually found in September or February, booked 58 days in advance, depart on a Wednesday or Tuesday and return on a Monday

Cheap flight deals from Durham to Santo Domingo

Keep the following information in mind while searching for Durham to Santo Domingo flight deals. Data was last updated July 31, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Durham to Santo Domingo

Cheapest flights from Durham to Santo DomingoExplore the most affordable flight options available from Durham to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Explore the most affordable flight options available from Durham to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Durham to Santo Domingo that are best for you.

Best time to book a flight from Durham to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Durham with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Durham to Santo Domingo

How far ahead should I book a flight from Durham to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Durham to Santo Domingo. Price data was last updated on July 25, 2025.

What is the cheapest month to book a flight from Durham to Santo Domingo?

What is the cheapest time of day to fly from DU8 to SDQ?

Find hourly flight availability from Durham to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

What is the cheapest day to fly from Durham to Santo Domingo?

Use this chart to determine the cheapest time to fly round-trip from Durham to Santo Domingo. Price data was last updated on September 1, 2024.

Reviews of airlines servicing Santo Domingo

Read through reviews of airlines operating flights from Durham to Santo Domingo, such as Delta, JetBlue, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Durham to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santo Domingo from Durham?

What are the cheapest airlines to fly from Durham to Santo Domingo one-way?

Can I find deals for flights from Durham to Santo Domingo that include hotel bookings?

How can I find direct flights from Durham to Santo Domingo?

Can I find deals for business class flights from Durham to Santo Domingo?

What is the cheapest month to book a flight from Durham to Santo Domingo?

Traveling to a place near Santo Domingo?

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Alternative routes for Durham to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Durham to Santo Domingo

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Cheapest flights from Durham to Santo Domingo
Explore the most affordable flight options available from Durham to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.