$233+ Cheap flights from Columbus to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — SDQ
Jun 5 — Jun 121
Round-trip
1 adult, Economy
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Find cheap flights from Columbus to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbus to Santo Domingo
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Best
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One-way
Cheapest flights from Columbus to Santo DomingoExplore the most affordable flight options available from Columbus to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
Explore the most affordable flight options available from Columbus to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:05 am
CMH
- SDQ
1 stop6h 18m
Delta
Wed 6/106:06 am
SDQ
- CMH
1 stop11h 53m
Delta
Deal found 5/4![Delta logo]()
$540
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
CMH
- SDQ
2 stops12h 35m
American Airlines
Tue 6/97:00 am
SDQ
- CMH
1 stop15h 37m
American Airlines
Deal found 5/5![American Airlines logo]()
$545
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:10 pm
CMH
- SDQ
1 stop18h 35m
American Airlines
Tue 6/97:00 am
SDQ
- CMH
1 stop15h 37m
American Airlines
Deal found 5/2![American Airlines logo]()
$548
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:19 pm
CMH
- SDQ
1 stop15h 08m
American Airlines
Thu 8/62:00 pm
SDQ
- CMH
1 stop20h 09m
American Airlines
Deal found 5/1![American Airlines logo]()
$549
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:36 am
CMH
- SDQ
2 stops11h 19m
American Airlines
Wed 6/1010:25 am
SDQ
- CMH
2 stops13h 17m
American Airlines
Deal found 5/4![American Airlines logo]()
$554
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:08 am
CMH
- SDQ
1 stop10h 16m
American Airlines
Wed 7/222:20 pm
SDQ
- CMH
1 stop10h 17m
American Airlines
Deal found 5/3![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:12 pm
CMH
- SDQ
2 stops9h 48m
American Airlines
Sat 9/261:35 pm
SDQ
- CMH
2 stops10h 27m
American Airlines
Deal found 5/1![American Airlines logo]()
$565
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:10 pm
CMH
- SDQ
1 stop18h 35m
American Airlines
Mon 6/81:45 pm
SDQ
- CMH
1 stop9h 57m
American Airlines
Deal found 5/4![American Airlines logo]()
$568
Best flights from Columbus to Santo DomingoDiscover carefully curated flight deals from Columbus to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
Discover carefully curated flight deals from Columbus to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 6, 2026.
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:03 am
CMH
- SDQ
1 stop11h 03m
Delta
Wed 8/52:42 pm
SDQ
- CMH
1 stop10h 06m
Delta
Deal found 5/1![Delta logo]()
$540
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:36 am
CMH
- SDQ
2 stops11h 19m
American Airlines
Wed 6/1010:25 am
SDQ
- CMH
2 stops13h 17m
American Airlines
Deal found 5/4![American Airlines logo]()
$554
This Copa Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/611:03 am
CMH
- SDQ
2 stops24h 39m
Copa Airlines
Mon 7/208:53 am
SDQ
- CMH
2 stops24h 56m
Copa Airlines
Deal found 5/3![Copa Airlines logo]()
$633
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:05 am
CMH
- SDQ
1 stop7h 18m
Delta
Tue 6/92:41 pm
SDQ
- CMH
1 stop9h 50m
Delta
Deal found 5/2![Delta logo]()
$540
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:00 am
CMH
- SDQ
1 stop14h 25m
American Airlines
Wed 8/52:22 pm
SDQ
- CMH
2 stops18h 17m
American Airlines
Deal found 5/3![American Airlines logo]()
$584
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:36 am
CMH
- SDQ
2 stops14h 05m
Delta
Wed 6/102:41 pm
SDQ
- CMH
1 stop6h 50m
Delta
Deal found 5/2![Delta logo]()
$565
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:15 pm
CMH
- SDQ
2 stops10h 40m
American Airlines
Tue 6/97:00 am
SDQ
- CMH
2 stops11h 45m
American Airlines
Deal found 5/6![American Airlines logo]()
$590
This Copa Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
CMH
- SDQ
2 stops16h 56m
Copa Airlines
Sun 5/242:14 pm
SDQ
- CMH
2 stops19h 35m
Copa Airlines
Deal found 5/1![Copa Airlines logo]()
$653
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:05 am
CMH
- SDQ
2 stops9h 54m
American Airlines
Tue 6/3010:29 am
SDQ
- CMH
2 stops13h 13m
American Airlines
Deal found 5/6![American Airlines logo]()
$648
Last-minute flights from Columbus to Santo DomingoDiscover last-minute flight deals from Columbus to Santo Domingo. Data last updated May 6, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Santo Domingo. Data last updated May 6, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3010:44 am
CMH
- SDQ
2 stops12h 11m
American Airlines
Sat 6/610:25 am
SDQ
- CMH
2 stops13h 17m
American Airlines
Deal found 5/2![American Airlines logo]()
$585
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:10 pm
CMH
- SDQ
1 stop18h 35m
American Airlines
Tue 6/97:00 am
SDQ
- CMH
1 stop15h 37m
American Airlines
Deal found 5/2![American Airlines logo]()
$548
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:10 pm
CMH
- SDQ
1 stop18h 35m
American Airlines
Mon 6/81:45 pm
SDQ
- CMH
1 stop9h 57m
American Airlines
Deal found 5/4![American Airlines logo]()
$568
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
CMH
- SDQ
2 stops12h 35m
American Airlines
Tue 6/97:00 am
SDQ
- CMH
1 stop15h 37m
American Airlines
Deal found 5/5![American Airlines logo]()
$545
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:05 am
CMH
- SDQ
1 stop6h 18m
Delta
Wed 6/106:06 am
SDQ
- CMH
1 stop11h 53m
Delta
Deal found 5/5![Delta logo]()
$540
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:36 am
CMH
- SDQ
2 stops11h 19m
American Airlines
Wed 6/1010:25 am
SDQ
- CMH
2 stops13h 17m
American Airlines
Deal found 5/4![American Airlines logo]()
$554
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:36 am
CMH
- SDQ
2 stops14h 05m
Delta
Wed 6/102:41 pm
SDQ
- CMH
1 stop6h 50m
Delta
Deal found 5/2![Delta logo]()
$565
One-way flights from Columbus to Santo DomingoSearch for one-way flight options from Columbus to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
Search for one-way flight options from Columbus to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated May 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/316:05 pm
CMH
- SDQ
3 stops32h 35m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:05 pm
CMH
- SDQ
2 stops22h 25m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:58 pm
CMH
- SDQ
3 stops43h 31m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:28 pm
CMH
- SDQ
3 stops35h 01m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:28 pm
CMH
- SDQ
3 stops24h 50m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:05 am
CMH
- SDQ
1 stop6h 18m
Delta
Deal found 5/3![Delta logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:48 pm
CMH
- SDQ
3 stops46h 30m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$322
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/51:01 pm
CMH
- SDQ
2 stops9h 54m
American Airlines
Deal found 5/2![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:13 pm
CMH
- SDQ
1 stop15h 16m
American Airlines
Deal found 5/2![American Airlines logo]()
$325
Find flight deals from Columbus to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 6, 2026.
Round-trip from | $540 (Delta) |
|---|---|
One-way from | $233 (Kiwi.com) |
Popular in | November |
Cheapest in | March |
Average price | $563 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Columbus to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Wed 7/29
7:03 am-6:06 pm
1 stop11h 03m
Santo Domingo Las Americas
Wed 8/5
2:42 pm-12:48 am
1 stop10h 06m
$540
Quickest round-trip
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Wed 6/3
6:05 am-1:23 pm
1 stop7h 18m
Santo Domingo Las Americas
Tue 6/9
2:41 pm-12:31 am
1 stop9h 50m
$540
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Wed 6/3
11:36 am-10:55 pm
2 stops11h 19m
Santo Domingo Las Americas
Wed 6/10
10:25 am-11:42 pm
2 stops13h 17m
$554
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Thu 6/4
10:36 am-12:41 am
2 stops14h 05m
Santo Domingo Las Americas
Wed 6/10
2:41 pm-9:31 pm
1 stop6h 50m
$565
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Wed 7/29
7:00 am-9:25 pm
1 stop14h 25m
Santo Domingo Las Americas
Wed 8/5
2:22 pm-8:39 am
2 stops18h 17m
$584
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Tue 6/2
12:15 pm-10:55 pm
2 stops10h 40m
Santo Domingo Las Americas
Tue 6/9
7:00 am-6:45 pm
2 stops11h 45m
$590
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Mon 7/6
11:03 am-11:42 am
2 stops24h 39m
Santo Domingo Las Americas
Mon 7/20
8:53 am-9:49 am
2 stops24h 56m
$633
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Wed 5/20
5:05 am-2:59 pm
2 stops9h 54m
Santo Domingo Las Americas
Tue 6/30
10:29 am-11:42 pm
2 stops13h 13m
$648
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Tue 5/19
6:00 am-10:56 pm
2 stops16h 56m
Santo Domingo Las Americas
Sun 5/24
2:14 pm-9:49 am
2 stops19h 35m
$653
Cheapest one-way
Quickest one-way
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Wed 6/3
7:05 am-1:23 pm
1 stop6h 18m
$318
Showing 1-10 of 14 resultsSorted by cheapest first
Best time to book a flight from Columbus to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Columbus with our price prediction graph.
C01-SDQ
CMH-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus to Santo Domingo
C01-SDQ
CMH-SDQ
How far ahead should I book a flight from Columbus to Santo Domingo?
The best time to book flights from Columbus to Santo Domingo is 69 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Columbus to Santo Domingo?
Currently, April is the cheapest month in which you can book a flight from Columbus to Santo Domingo (average of $184). Flying from Columbus to Santo Domingo in March is currently the most expensive (average of $412). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Columbus to Santo Domingo?
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated May 6, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Columbus to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Food
7.2
Comfort
7.9
Reviews
1 / 20
4.0
OkayJoel,May 2026
ATL - JAX
Related info for your journey
Find useful and relevant information for your journey from Columbus to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Complete your trip
Complete your trip to Santo Domingo by adding a car rental and/or hotel reservation to your travel itinerary.
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Columbus and Santo Domingo flights
Browse other Columbus and Santo Domingo flight options. Last updated on May 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santo Domingo
Explore flights to Santo Domingo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 6, 2026.
Top 5 airlines flying from Columbus to Santo Domingo
Discover the top 5 airlines that operate flights from Columbus to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$247 | Average$429 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$342 | Average$448 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$464 | Average$573 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$467 | Average$664 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$528 | Average$593 | FlexibilityNo cancel fee | On-time71% |