$227+ Cheap flights from Columbus to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — SDQ
Jul 21 — Jul 281
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest
Best
Last-minute
One-way
Cheapest flights from Columbus to Santo DomingoExplore the most affordable flight options available from Columbus to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
Explore the most affordable flight options available from Columbus to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:09 am
CMH
- SDQ
1 stop8h 08m
American Airlines
Thu 9/1710:27 am
SDQ
- CMH
1 stop12h 13m
American Airlines
Deal found 6/20![American Airlines logo]()
$540
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:08 am
CMH
- SDQ
1 stop16h 17m
American Airlines
Wed 8/52:00 pm
SDQ
- CMH
1 stop20h 09m
American Airlines
Deal found 6/16![American Airlines logo]()
$548
This Delta deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
CMH
- SDQ
1 stop7h 17m
Delta
Wed 8/57:35 pm
SDQ
- CMH
1 stop16h 13m
Delta
Deal found 6/19![Delta logo]()
$550
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:16 am
CMH
- SDQ
1 stop9h 08m
American Airlines
Wed 8/262:22 pm
SDQ
- CMH
1 stop8h 23m
American Airlines
Deal found 6/20![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:14 pm
CMH
- SDQ
1 stop18h 43m
American Airlines
Fri 8/72:00 pm
SDQ
- CMH
1 stop9h 44m
American Airlines
Deal found 6/20![American Airlines logo]()
$568
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:00 am
CMH
- SDQ
2 stops12h 44m
American Airlines
Mon 8/102:00 pm
SDQ
- CMH
1 stop22h 15m
American Airlines
Deal found 6/16![American Airlines logo]()
$573
Best flights from Columbus to Santo DomingoDiscover carefully curated flight deals from Columbus to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
Discover carefully curated flight deals from Columbus to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:03 am
CMH
- SDQ
1 stop11h 03m
Delta
Wed 8/57:35 pm
SDQ
- CMH
1 stop16h 13m
Delta
Deal found 6/20![Delta logo]()
$540
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:09 am
CMH
- SDQ
1 stop8h 08m
American Airlines
Thu 9/1710:27 am
SDQ
- CMH
1 stop12h 13m
American Airlines
Deal found 6/20![American Airlines logo]()
$540
This United Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/111:05 am
CMH
- SDQ
2 stops11h 41m
United Airlines
Sun 9/66:00 am
SDQ
- CMH
1 stop11h 08m
United Airlines
Deal found 6/17![United Airlines logo]()
$600
This American Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:09 am
CMH
- SDQ
1 stop8h 08m
American Airlines
Sun 9/2010:27 am
SDQ
- CMH
1 stop12h 13m
American Airlines
Deal found 6/18![American Airlines logo]()
$575
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/267:03 am
CMH
- SDQ
1 stop11h 03m
Delta
Fri 8/76:05 am
SDQ
- CMH
1 stop11h 29m
Delta
Deal found 6/18![Delta logo]()
$584
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:09 pm
CMH
- SDQ
1 stop19h 13m
American Airlines
Sun 10/47:34 pm
SDQ
- CMH
1 stop22h 38m
American Airlines
Deal found 6/20![American Airlines logo]()
$599
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:00 am
CMH
- SDQ
2 stops10h 44m
American Airlines
Sun 9/610:27 am
SDQ
- CMH
2 stops13h 09m
American Airlines
Deal found 6/16![American Airlines logo]()
$620
Last-minute flights from Columbus to Santo DomingoDiscover last-minute flight deals from Columbus to Santo Domingo. Data last updated June 21, 2026 and is based on user searches.
Discover last-minute flight deals from Columbus to Santo Domingo. Data last updated June 21, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/257:03 am
CMH
- SDQ
1 stop17h 51m
Delta
Thu 8/67:35 pm
SDQ
- CMH
1 stop16h 13m
Delta
Deal found 6/16![Delta logo]()
$620
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:14 pm
CMH
- SDQ
1 stop18h 43m
American Airlines
Fri 8/72:00 pm
SDQ
- CMH
1 stop9h 44m
American Airlines
Deal found 6/20![American Airlines logo]()
$568
This Delta deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/267:03 am
CMH
- SDQ
1 stop11h 03m
Delta
Fri 8/76:05 am
SDQ
- CMH
1 stop11h 29m
Delta
Deal found 6/18![Delta logo]()
$584
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/267:03 am
CMH
- SDQ
1 stop17h 51m
Delta
Thu 8/67:35 pm
SDQ
- CMH
2 stops20h 31m
Delta
Deal found 6/16![Delta logo]()
$625
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:03 am
CMH
- SDQ
1 stop11h 03m
Delta
Wed 8/57:35 pm
SDQ
- CMH
1 stop16h 13m
Delta
Deal found 6/20![Delta logo]()
$540
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:08 am
CMH
- SDQ
1 stop16h 17m
American Airlines
Wed 8/52:00 pm
SDQ
- CMH
1 stop20h 09m
American Airlines
Deal found 6/16![American Airlines logo]()
$548
One-way flights from Columbus to Santo DomingoSearch for one-way flight options from Columbus to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
Search for one-way flight options from Columbus to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:44 pm
CMH
- SDQ
2 stops22h 45m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$227
This eDestinos deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:44 pm
CMH
- SDQ
2 stops41h 19m
Frontier
Deal found 6/16![Frontier logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:45 pm
CMH
- SDQ
3 stops23h 33m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:59 pm
CMH
- SDQ
3 stops43h 30m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
CMH
- SDQ
2 stops18h 54m
Delta
Deal found 6/20![Delta logo]()
$318
This Copa Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am
CMH
- SDQ
2 stops28h 55m
Copa Airlines
Deal found 6/20![Copa Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:16 am
CMH
- SDQ
1 stop7h 06m
American Airlines
Deal found 6/20![American Airlines logo]()
$326
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:03 am
CMH
- SDQ
1 stop11h 03m
Delta
Deal found 6/20![Delta logo]()
$338
Find flight deals from Columbus to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Columbus (C01) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 21, 2026.
Round-trip from | $540 (American Airlines) |
|---|---|
One-way from | $227 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $600 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbus to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from Columbus to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Wed 7/29
7:03 am-6:06 pm
1 stop11h 03m
Santo Domingo Las Americas
Wed 8/5
7:35 pm-11:48 am
1 stop16h 13m
$540
Quickest round-trip
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Thu 9/10
7:09 am-3:17 pm
1 stop8h 08m
Santo Domingo Las Americas
Thu 9/17
10:27 am-10:40 pm
1 stop12h 13m
$540
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Thu 9/17
7:09 am-3:17 pm
1 stop8h 08m
Santo Domingo Las Americas
Sun 9/20
10:27 am-10:40 pm
1 stop12h 13m
$575
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Sun 7/26
7:03 am-6:06 pm
1 stop11h 03m
Santo Domingo Las Americas
Fri 8/7
6:05 am-5:34 pm
1 stop11h 29m
$584
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Fri 9/18
2:09 pm-9:22 am
1 stop19h 13m
Santo Domingo Las Americas
Sun 10/4
7:34 pm-6:12 pm
1 stop22h 38m
$599
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Tue 9/1
11:05 am-10:46 pm
2 stops11h 41m
Santo Domingo Las Americas
Sun 9/6
6:00 am-5:08 pm
1 stop11h 08m
$600
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Tue 9/1
8:00 am-6:44 pm
2 stops10h 44m
Santo Domingo Las Americas
Sun 9/6
10:27 am-11:36 pm
2 stops13h 09m
$620
Cheapest one-way
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Tue 7/7
5:44 pm-11:03 am
2 stops41h 19m
$256
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Fri 8/21
10:10 am-11:03 am
2 stops24h 53m
$301
ColumbusSanto Domingo
CMH - SDQ
CMHSDQ
Columbus
Wed 8/5
8:59 pm-4:29 pm
3 stops43h 30m
$311
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from Columbus to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Columbus with our price prediction graph.
C01-SDQ
CMH-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbus to Santo Domingo
C01-SDQ
CMH-SDQ
What is the cheapest month to book a flight from Columbus to Santo Domingo?
Currently, April is the cheapest month in which you can book a flight from Columbus to Santo Domingo (average of $184). Flying from Columbus to Santo Domingo in May is currently the most expensive (average of $467). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Columbus to Santo Domingo?
How far ahead should I book a flight from Columbus to Santo Domingo?
The best time to book flights from Columbus to Santo Domingo is 34 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated June 21, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Columbus to Santo Domingo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.8
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Columbus to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Complete your trip
Complete your trip to Santo Domingo by adding a car rental and/or hotel reservation to your travel itinerary.
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Columbus and Santo Domingo flights
Browse other Columbus and Santo Domingo flight options. Last updated on June 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santo Domingo
Explore flights to Santo Domingo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 21, 2026.
Top 4 airlines flying from Columbus to Santo Domingo
Discover the top 4 airlines that operate flights from Columbus to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$247 | Average$429 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$440 | Average$578 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$467 | Average$687 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$538 | Average$677 | FlexibilityNo cancel fee | On-time71% |