How long is the flight from Cali to Santo Domingo?

There are many flights that can get you from Cali to Santo Domingo in 12h 38m. Fly via Copa Airlines to get the fastest option. The distance from Cali to Santo Domingo is about 1123 mi.

What are the cheapest airlines flying from Cali to Santo Domingo round-trip?

Flying on Avianca is currently your cheapest option to Santo Domingo, with prices starting at $284. Another option worth looking into is Copa Airlines, starting at $328 round trip. Users have found that Avianca is 22% cheaper than the other options available to this destination.

What is the cheapest day to fly from Cali to Santo Domingo?

Travelers seeking maximum savings on their Cali to Santo Domingo flight should consider departing on Friday mornings when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What is the cheapest day to fly round-trip from Cali to Santo Domingo?

Flying to your destination on a Wednesday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to Santo Domingo. Check prices with Cheapflights to find a great deal for your trip.

How far in advance should I book a flight from Cali to Santo Domingo?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 54 days in advance, which can save you up to 36% on flights from Cali to Santo Domingo compared to booking the week you need them. Waiting 54 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $356. For sooner than that we have options available in the next 3 days from $370.

What is the cheapest month to fly from Cali to Santo Domingo?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, September can be a great choice for travel to Santo Domingo. Flights to Santo Domingo from Cali in September are about $365 on average during September, but can be found for as low as $306.

What is the cheapest time of day to fly from CLO to SDQ?

It’s optimal to fly from Cali to Santo Domingo in the afternoon. By choosing this option you can save up to 6% on the cost of your flight, compared to a flight at noon.

Can I find deals for flights from Cali to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Cali to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Cali to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Santo Domingo.

Can I find deals for business class flights from Cali to Santo Domingo?

Yes. Cheapflights offers flight deals from Cali to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$210+ Flights from Cali to Santo Domingo

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Cali Alfonso B. Aragon Intl to Santo Domingo Las Americas are usually found in September or February, booked 53 days in advance, depart on a Friday or Wednesday and return on a Tuesday

Cheap flight deals from Cali to Santo Domingo

Round-trip from	$339 (Copa Airlines)
One-way from	$210 (Avianca)
Popular in	December
Cheapest in	September
Average price	$337

From Cali Alfonso B. Aragon Intl to Santo Domingo Las Americas

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One-way flight from Cali Alfonso B. Aragon Intl to Santo Domingo Las Americas

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Highest demand for flights based on searches. 8% potential increase in price ($32 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from Cali to Santo Domingo

Cheapest flights from Cali to Santo Domingo
Explore the most affordable flight options available from Cali to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Thu 10/238:47 amCLO - SDQ

1 stop6h 28mCopa Airlines

Tue 10/286:43 pmSDQ - CLO

1 stop5h 52mCopa Airlines

Deal found 9/10

$339

Sat 10/118:47 amCLO - SDQ

1 stop6h 28mCopa Airlines

Tue 12/96:00 amSDQ - CLO

1 stop6h 01mCopa Airlines

Deal found 9/11

$340

Fri 10/248:47 amCLO - SDQ

1 stop12h 38mCopa Airlines

Sun 11/25:00 amSDQ - CLO

1 stop9h 11mCopa Airlines

Deal found 9/11

$341

Wed 11/58:48 amCLO - SDQ

1 stop12h 37mCopa Airlines

Sun 11/96:00 amSDQ - CLO

1 stop9h 11mCopa Airlines

Deal found 9/11

$342

Tue 9/167:40 pmCLO - SDQ

1 stop28h 40mMultiple Airlines

Mon 9/222:24 amSDQ - CLO

1 stop7h 01mMultiple Airlines

Deal found 9/10

$345

Thu 10/307:55 amCLO - SDQ

1 stop7h 55mAvianca

Sun 11/25:45 pmSDQ - CLO

1 stop13h 25mAvianca

Deal found 9/11

$351

Thu 10/3010:25 pmCLO - SDQ

1 stop17h 25mMultiple Airlines

Sun 11/27:35 amSDQ - CLO

1 stop6h 45mMultiple Airlines

Deal found 9/11

$352

Tue 11/184:52 amCLO - SDQ

1 stop7h 20mCopa Airlines

Sun 11/236:00 amSDQ - CLO

1 stop9h 11mCopa Airlines

Deal found 9/10

$366

Fri 9/1912:01 pmCLO - SDQ

1 stop27h 16mCopa Airlines

Mon 9/226:17 pmSDQ - CLO

1 stop17h 41mCopa Airlines

Deal found 9/11

$374

Thu 9/1112:01 pmCLO - SDQ

1 stop9h 25mCopa Airlines

Thu 9/1811:56 amSDQ - CLO

1 stop12h 26mCopa Airlines

Deal found 9/10

$378

Best flights from Cali to Santo Domingo
Discover carefully curated flight deals from Cali to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2025.

Thu 10/238:47 amCLO - SDQ

1 stop12h 38mCopa Airlines

Mon 10/278:58 amSDQ - CLO

1 stop9h 31mCopa Airlines

Deal found 9/10

$339

Wed 9/2412:01 pmCLO - SDQ

1 stop9h 25mCopa Airlines

Mon 9/298:59 amSDQ - CLO

1 stop6h 22mCopa Airlines

Deal found 9/10

$339

Thu 10/2312:01 pmCLO - SDQ

1 stop9h 24mCopa Airlines

Tue 10/288:58 amSDQ - CLO

1 stop15h 37mCopa Airlines

Deal found 9/9

$339

Thu 10/168:47 amCLO - SDQ

1 stop12h 38mCopa Airlines

Thu 10/232:10 pmSDQ - CLO

1 stop10h 16mCopa Airlines

Deal found 9/10

$339

Tue 9/3012:01 pmCLO - SDQ

1 stop9h 25mCopa Airlines

Tue 10/75:25 amSDQ - CLO

1 stop6h 33mCopa Airlines

Deal found 9/10

$339

Mon 9/223:23 pmCLO - SDQ

1 stop10h 13mCopa Airlines

Fri 10/1711:57 amSDQ - CLO

1 stop12h 29mCopa Airlines

Deal found 9/11

$339

Thu 10/168:47 amCLO - SDQ

1 stop6h 28mCopa Airlines

Sun 10/266:00 amSDQ - CLO

1 stop9h 11mCopa Airlines

Deal found 9/9

$339

Wed 9/248:48 amCLO - SDQ

1 stop6h 29mCopa Airlines

Tue 9/308:59 amSDQ - CLO

1 stop6h 22mCopa Airlines

Deal found 9/11

$339

Last-minute flights from Cali to Santo Domingo
Discover last-minute flight deals from Cali to Santo Domingo. Data last updated September 11, 2025 and is based on user searches.

Thu 9/1112:01 pmCLO - SDQ

1 stop9h 25mCopa Airlines

Thu 9/1811:56 amSDQ - CLO

1 stop12h 26mCopa Airlines

Deal found 9/10

$378

Tue 9/167:40 pmCLO - SDQ

1 stop28h 40mMultiple Airlines

Mon 9/222:24 amSDQ - CLO

1 stop7h 01mMultiple Airlines

Deal found 9/10

$345

Fri 9/1912:01 pmCLO - SDQ

1 stop27h 16mCopa Airlines

Mon 9/226:17 pmSDQ - CLO

1 stop17h 41mCopa Airlines

Deal found 9/11

$374

Sat 10/118:47 amCLO - SDQ

1 stop6h 28mCopa Airlines

Tue 12/96:00 amSDQ - CLO

1 stop6h 01mCopa Airlines

Deal found 9/11

$340

Thu 10/238:47 amCLO - SDQ

1 stop6h 28mCopa Airlines

Mon 10/278:58 amSDQ - CLO

1 stop6h 13mCopa Airlines

Deal found 9/11

$339

Fri 10/248:47 amCLO - SDQ

1 stop12h 38mCopa Airlines

Sun 11/25:00 amSDQ - CLO

1 stop9h 11mCopa Airlines

Deal found 9/11

$341

Thu 10/307:55 amCLO - SDQ

1 stop7h 55mAvianca

Sun 11/25:45 pmSDQ - CLO

1 stop13h 25mAvianca

Deal found 9/11

$351

Thu 10/3010:25 pmCLO - SDQ

1 stop17h 25mMultiple Airlines

Sun 11/27:35 amSDQ - CLO

1 stop6h 45mMultiple Airlines

Deal found 9/11

$352

One-way flights from Cali to Santo Domingo
Search for one-way flight options from Cali to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated September 11, 2025.

Sat 11/87:55 amCLO - SDQ

1 stop7h 55mAvianca

Deal found 9/10

$210

Wed 11/129:50 amCLO - SDQ

1 stop6h 00mAvianca

Deal found 9/10

$221

Fri 11/74:52 amCLO - SDQ

1 stop7h 20mCopa Airlines

Deal found 9/10

$232

Tue 11/114:52 amCLO - SDQ

1 stop10h 23mCopa Airlines

Deal found 9/11

$233

Fri 11/74:52 amCLO - SDQ

2 stops17h 54mUnited Airlines

Deal found 9/11

$1,284

Cheapflights Fare Finder

Use the filters below to find and compare flights from Cali to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Thu 10/23

8:47 am-10:25 pm

1 stop12h 38m

Santo Domingo Las Americas

Mon 10/27

8:58 am-5:29 pm

1 stop9h 31m

$339

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Wed 9/24

12:01 pm-10:26 pm

1 stop9h 25m

Santo Domingo Las Americas

Mon 9/29

8:59 am-2:21 pm

1 stop6h 22m

$339

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Thu 10/23

12:01 pm-10:25 pm

1 stop9h 24m

Santo Domingo Las Americas

Tue 10/28

8:58 am-11:35 pm

1 stop15h 37m

$339

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Thu 10/16

8:47 am-10:25 pm

1 stop12h 38m

Santo Domingo Las Americas

Thu 10/23

2:10 pm-11:26 pm

1 stop10h 16m

$339

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Tue 9/30

12:01 pm-10:26 pm

1 stop9h 25m

Santo Domingo Las Americas

Tue 10/7

5:25 am-10:58 am

1 stop6h 33m

$339

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Mon 9/22

3:23 pm-2:36 am

1 stop10h 13m

Santo Domingo Las Americas

Fri 10/17

11:57 am-11:26 pm

1 stop12h 29m

$339

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Thu 10/16

8:47 am-4:15 pm

1 stop6h 28m

Santo Domingo Las Americas

Sun 10/26

6:00 am-2:11 pm

1 stop9h 11m

$339

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Wed 9/24

8:48 am-4:17 pm

1 stop6h 29m

Santo Domingo Las Americas

Tue 9/30

8:59 am-2:21 pm

1 stop6h 22m

$339

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Sat 11/8

7:55 am-4:50 pm

1 stop7h 55m

$210

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Wed 11/12

9:50 am-4:50 pm

1 stop6h 00m

$221

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 13 results

Best time to book a flight from Cali to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Cali with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Santo Domingo

How far ahead should I book a flight from Cali to Santo Domingo?

The best time to book flights from Cali to Santo Domingo is 53 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Cali to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Cali to Santo Domingo (average of $362). Flying from Cali to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Cali to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Copa Airlines

7.6

Good

1,531 reviews

Reviews

1 / 20

10.0

Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Copa Airlines

7.6

Good

1,531 reviews

Copa Airlines

7.6

Good

1,531 reviews

Reviews

1 / 20

10.0

Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Avianca

6.7

Okay

2,436 reviews

Copa Airlines

7.6

Good

1,531 reviews

Reviews

1 / 20

10.0

Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

How long is the flight from Cali to Santo Domingo?
There are many flights that can get you from Cali to Santo Domingo in 12h 38m. Fly via Copa Airlines to get the fastest option. The distance from Cali to Santo Domingo is about 1123 mi.
What are the cheapest airlines flying from Cali to Santo Domingo round-trip?
Flying on Avianca is currently your cheapest option to Santo Domingo, with prices starting at $284. Another option worth looking into is Copa Airlines, starting at $328 round trip. Users have found that Avianca is 22% cheaper than the other options available to this destination.
Can I find deals for flights from Cali to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Cali to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Cali to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Santo Domingo.
Can I find deals for business class flights from Cali to Santo Domingo?
Yes. Cheapflights offers flight deals from Cali to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Cali to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Cali to Santo Domingo (average of $362). Flying from Cali to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Cali to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time
Avianca	Cheapest$284	Average$365	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$328	Average$376	FlexibilityNo cancel fee	On-time70%

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$210+ Cheap flights from Cali (CLO) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheapflights Tip: The best prices from Cali Alfonso B. Aragon Intl to Santo Domingo Las Americas are usually found in September or February, booked 53 days in advance, depart on a Friday or Wednesday and return on a Tuesday

Cheap flight deals from Cali to Santo Domingo

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Cali to Santo Domingo

Cheapest flights from Cali to Santo DomingoExplore the most affordable flight options available from Cali to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Explore the most affordable flight options available from Cali to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Cali to Santo Domingo that are best for you.

Best time to book a flight from Cali to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Cali with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Cali to Santo Domingo

How far ahead should I book a flight from Cali to Santo Domingo?

What is the cheapest month to book a flight from Cali to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Cali to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Cali to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Cali to Santo Domingo?

What are the cheapest airlines flying from Cali to Santo Domingo round-trip?

Can I find deals for flights from Cali to Santo Domingo that include hotel bookings?

How can I find direct flights from Cali to Santo Domingo?

Can I find deals for business class flights from Cali to Santo Domingo?

What is the cheapest month to book a flight from Cali to Santo Domingo?

Traveling to a place near Santo Domingo?

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Alternative routes for Cali to Santo Domingo

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Top 2 airlines flying from Cali to Santo Domingo

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Cheapest flights from Cali to Santo Domingo
Explore the most affordable flight options available from Cali to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.