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Santo Domingo

$342+ Cheap flights from Cali (CLO) to Santo Domingo (SDQ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
CLO — SDQ
fev 27 — mar 61
sex 2/27
sex 3/6
1 adult, Economy
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Cheap flight deals from Cali to Santo Domingo

Cheapest flights from Cali to Santo Domingo
Explore the most affordable flight options available from Cali to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on janeiro 28, 2026.

This Copa Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 2/512:03 pm
CLO
-
SDQ
1 stop9h 36m
Copa Airlines
qua 2/118:50 am
SDQ
-
CLO
1 stop15h 46m
Copa Airlines
Deal found 1/27$342
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 3/1410:26 pm
CLO
-
SDQ
2 stops14h 24m
Multiple Airlines
sáb 3/217:35 am
SDQ
-
CLO
1 stop14h 03m
Multiple Airlines
Deal found 1/27$351
This Copa Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 4/112:06 pm
CLO
-
SDQ
1 stop13h 14m
Copa Airlines
ter 4/78:43 am
SDQ
-
CLO
1 stop6h 27m
Copa Airlines
Deal found 1/27$353
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 2/273:34 am
CLO
-
SDQ
2 stops9h 23m
Multiple Airlines
qua 3/411:50 pm
SDQ
-
CLO
1 stop7h 28m
Multiple Airlines
Deal found 1/26$354
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 2/1211:40 am
CLO
-
SDQ
1 stop6h 02m
Multiple Airlines
qui 2/197:32 pm
SDQ
-
CLO
2 stops8h 22m
Multiple Airlines
Deal found 1/27$359
This Copa Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qui 4/235:00 am
CLO
-
SDQ
1 stop7h 12m
Copa Airlines
dom 5/38:45 am
SDQ
-
CLO
1 stop9h 51m
Copa Airlines
Deal found 1/26$383
This Copa Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 4/245:00 am
CLO
-
SDQ
1 stop5h 41m
Copa Airlines
sex 4/242:12 pm
SDQ
-
CLO
1 stop10h 24m
Copa Airlines
Deal found 1/27$388
This Priceline deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 1/3110:55 am
CLO
-
SDQ
1 stop4h 55m
Avianca
seg 2/25:45 pm
SDQ
-
CLO
1 stop6h 25m
Avianca
Deal found 1/27$395
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 2/210:15 am
CLO
-
SDQ
1 stop5h 35m
Avianca
ter 2/105:45 pm
SDQ
-
CLO
1 stop4h 55m
Avianca
Deal found 1/27$397

Find flight deals from Cali to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Cali (CLO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated janeiro 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$342
(Copa Airlines)

Popular in

December

Cheapest in

September

Average price

$391
Provider with most accurate pricing for Cali Alfonso B. Aragon Intl-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cali Alfonso B. Aragon Intl-Santo Domingo Las Americas flights.
Search Deals
From Cali Alfonso B. Aragon Intl to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cali to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated janeiro 28, 2026.
Use the filters below to find and compare flights from Cali to Santo Domingo that are best for you.

Fly from

Cali

Fly to

Santo Domingo

Route

Depart

Return

Price

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

dom 3/15

5:03 am-1:11 pm

1 stop7h 08m

Santo Domingo Las Americas

seg 3/23

8:48 am-2:09 pm

1 stop6h 21m

$342

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

ter 2/10

5:03 am-10:50 am

1 stop4h 47m

Santo Domingo Las Americas

dom 2/15

11:57 am-11:36 pm

1 stop12h 39m

$342

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

dom 3/1

12:02 pm-10:40 pm

1 stop9h 38m

Santo Domingo Las Americas

qui 3/5

2:13 pm-11:34 pm

1 stop10h 21m

$342

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

qua 2/11

12:03 pm-2:17 am

1 stop13h 14m

Santo Domingo Las Americas

qua 2/25

8:50 am-2:10 pm

1 stop6h 20m

$342

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

ter 2/10

8:48 am-10:39 pm

1 stop12h 51m

Santo Domingo Las Americas

ter 2/24

6:00 am-5:50 pm

1 stop12h 50m

$342

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

qui 3/19

5:03 am-4:14 pm

1 stop10h 11m

Santo Domingo Las Americas

seg 3/23

8:48 am-2:09 pm

1 stop6h 21m

$342

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

sáb 3/14

10:26 pm-1:50 pm

2 stops14h 24m

Santo Domingo Las Americas

sáb 3/21

7:35 am-8:38 pm

1 stop14h 03m

$351

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

qua 4/1

8:46 am-10:51 pm

1 stop13h 05m

Santo Domingo Las Americas

ter 4/7

12:38 pm-5:36 pm

1 stop5h 58m

$353

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

sex 2/27

3:34 am-1:57 pm

2 stops9h 23m

Santo Domingo Las Americas

qua 3/4

11:50 pm-6:18 am

1 stop7h 28m

$354

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

qui 4/23

5:00 am-1:12 pm

1 stop7h 12m

Santo Domingo Las Americas

dom 5/3

8:45 am-5:36 pm

1 stop9h 51m

$383

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 11 results
1
2
  • Most accurate provider: When it comes to deals on Cali-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cali-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cali-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cali-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cali-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cali to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Cali with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Santo Domingo

How far ahead should I book a flight from Cali to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Cali to Santo Domingo. Price data was last updated on January 23, 2026.

The best time to book flights from Cali to Santo Domingo is 87 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Cali to Santo Domingo?

Currently, June is the cheapest month in which you can book a flight from Cali to Santo Domingo (average of $144). Flying from Cali to Santo Domingo in April is currently the most expensive (average of $342). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated janeiro 28, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Cali to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,560 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Copa Airlines
7.5
Good
1,560 reviews
Copa Airlines
7.5
Good
1,560 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it
Avianca
6.6
Okay
2,490 reviews
Copa Airlines
7.5
Good
1,560 reviews

Food

6.8

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Crew

8.1

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

Find useful and relevant information for your journey from Cali to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cali to Santo Domingo?

    There are many flights that can get you from Cali to Santo Domingo in 7h 08m. Fly via Copa Airlines to get the fastest option. The distance from Cali to Santo Domingo is about 1123 mi.

  • What are the cheapest airlines flying from Cali to Santo Domingo round-trip?

    Flying on Copa Airlines is currently your cheapest option to Santo Domingo, with prices starting at $310. Another option worth looking into is Avianca, starting at $350 round trip. Users have found that Copa Airlines is 15% cheaper than the other options available to this destination.

  • Can I find deals for flights from Cali to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Cali to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cali to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Santo Domingo.

  • Can I find deals for business class flights from Cali to Santo Domingo?

    Yes. Cheapflights offers flight deals from Cali to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cali to Santo Domingo?

    Currently, June is the cheapest month in which you can book a flight from Cali to Santo Domingo (average of $144). Flying from Cali to Santo Domingo in April is currently the most expensive (average of $342). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 2 airlines flying from Cali to Santo Domingo

Discover the top 2 airlines that operate flights from Cali to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated janeiro 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$310Average$354FlexibilityNo cancel feeOn-time70%
AviancaCheapest$350Average$390FlexibilityNo cancel feeOn-time71%

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