What are the cheapest airlines flying from Cali to Santo Domingo round-trip?

Flying on Copa Airlines is currently your cheapest option to Santo Domingo, with prices starting at $337. Additional round-trip tickets that might be worth considering are offered by Avianca and Delta, with the lowest prices starting at $349 and $6,889, respectively. Users have found that Copa Airlines is 6% cheaper than the other options available to this destination.

What is the cheapest day to fly from Cali to Santo Domingo?

Travelers seeking maximum savings on their Cali to Santo Domingo flight should consider departing on Friday mornings when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What is the cheapest day to fly round-trip from Cali to Santo Domingo?

Flying to your destination on a Wednesday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to Santo Domingo. Check prices with Cheapflights to find a great deal for your trip.

How far in advance should I book a flight from Cali to Santo Domingo?

When searching for a good deal, it’s best to be prepared for potential fluctuations in price. We recommend booking at least 54 days in advance, which can save you up to 31% on flights from Cali to Santo Domingo compared to booking the week you need them. Waiting 54 days out may not be for everyone, so we have options available for flights within the next two weeks, with the lowest price starting at $336. For sooner than that we have options available in the next 3 days from $377.

What is the cheapest month to fly from Cali to Santo Domingo?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, September can be a great choice for travel to Santo Domingo. Flights to Santo Domingo from Cali in September are about $361 on average during September, but can be found for as low as $292.

What is the cheapest time of day to fly from CLO to SDQ?

It’s optimal to fly from Cali to Santo Domingo in the afternoon. By choosing this option you can save up to 6% on the cost of your flight, compared to a flight at noon.

Can I find deals for flights from Cali to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Cali to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Cali to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Santo Domingo.

Can I find deals for business class flights from Cali to Santo Domingo?

Yes. Cheapflights offers flight deals from Cali to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$207+ Flights from Cali to Santo Domingo

Q: How much does it cost to fly round-trip from Cali to Santo Domingo?

Airfare is typical for this route at the moment. Cali to Santo Domingo flights typically cost between $330 and $379 in August. The cheapest round-trip price found within the last 3 days was $337 on Copa Airlines (Aug 21-Aug 28).

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Cali Alfonso B. Aragon Intl to Santo Domingo Las Americas are usually found in September or February, booked 53 days in advance, depart on a Friday or Wednesday and return on a Tuesday

Cheap flight deals from Cali to Santo Domingo

Round-trip from	$337 (Copa Airlines)
One-way from	$207 (Avianca)
Popular in	December
Cheapest in	September
Average price	$358

From Cali Alfonso B. Aragon Intl to Santo Domingo Las Americas

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One-way flight from Cali Alfonso B. Aragon Intl to Santo Domingo Las Americas

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Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Cali to Santo Domingo

Cheapest flights from Cali to Santo Domingo
Explore the most affordable flight options available from Cali to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Thu 8/213:23 pmCLO - SDQ

1 stop6h 03mCopa Airlines

Thu 8/2811:54 amSDQ - CLO

1 stop6h 31mCopa Airlines

Deal found 7/28

$337

Fri 8/226:51 amCLO - SDQ

1 stop9h 24mAvianca

Fri 8/296:10 pmSDQ - CLO

1 stop15h 08mAvianca

Deal found 7/29

$349

Mon 7/2810:00 pmCLO - SDQ

1 stop18h 15mMultiple Airlines

Fri 8/226:10 pmSDQ - CLO

2 stops13h 25mMultiple Airlines

Deal found 7/28

$390

Mon 7/2812:30 amCLO - SDQ

1 stop16h 50mAmerican Airlines

Fri 8/2910:25 amSDQ - CLO

1 stop27h 55mAmerican Airlines

Deal found 7/28

$1,402

Mon 9/2210:26 amCLO - SDQ

2 stops25h 58mDelta

Sat 10/43:06 pmSDQ - CLO

2 stops32h 04mDelta

Deal found 7/28

$6,889

Best flights from Cali to Santo Domingo
Discover carefully curated flight deals from Cali to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2025.

Thu 8/213:23 pmCLO - SDQ

1 stop6h 03mCopa Airlines

Thu 8/2811:54 amSDQ - CLO

1 stop6h 31mCopa Airlines

Deal found 7/28

$337

Fri 8/226:51 amCLO - SDQ

1 stop9h 24mAvianca

Fri 8/296:10 pmSDQ - CLO

1 stop15h 08mAvianca

Deal found 7/29

$349

Sat 12/136:39 amCLO - SDQ

1 stop6h 18mMultiple Airlines

Mon 1/121:24 amSDQ - CLO

1 stop7h 58mMultiple Airlines

Deal found 7/27

$414

Mon 9/225:26 amCLO - SDQ

2 stops30h 58mDelta

Fri 10/32:50 pmSDQ - CLO

2 stops27h 44mDelta

Deal found 7/28

$6,889

Last-minute flights from Cali to Santo Domingo
Discover last-minute flight deals from Cali to Santo Domingo. Data last updated July 29, 2025 and is based on user searches.

Tue 7/296:51 amCLO - SDQ

1 stop9h 24mMultiple Airlines

Fri 8/226:10 pmSDQ - CLO

2 stops13h 25mMultiple Airlines

Deal found 7/28

$390

Thu 8/73:23 pmCLO - SDQ

1 stop6h 03mCopa Airlines

Sun 8/105:23 amSDQ - CLO

1 stop6h 35mCopa Airlines

Deal found 7/26

$430

Thu 8/213:23 pmCLO - SDQ

1 stop6h 03mCopa Airlines

Thu 8/2811:54 amSDQ - CLO

1 stop6h 31mCopa Airlines

Deal found 7/28

$337

Fri 8/226:51 amCLO - SDQ

1 stop9h 24mAvianca

Fri 8/296:10 pmSDQ - CLO

1 stop15h 08mAvianca

Deal found 7/29

$349

One-way flights from Cali to Santo Domingo
Search for one-way flight options from Cali to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated July 29, 2025.

Sun 9/76:51 amCLO - SDQ

1 stop9h 24mAvianca

Deal found 7/29

$207

Sat 1/38:48 amCLO - SDQ

1 stop6h 24mCopa Airlines

Deal found 7/27

$306

Fly from

Fly to

Route

Depart

Return

Price

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Thu 8/21

3:23 pm-10:26 pm

1 stop6h 03m

Santo Domingo Las Americas

Thu 8/28

11:54 am-5:25 pm

1 stop6h 31m

$337

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Fri 8/22

6:51 am-5:15 pm

1 stop9h 24m

Santo Domingo Las Americas

Fri 8/29

6:10 pm-8:18 am

1 stop15h 08m

$349

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Sat 12/13

6:39 am-1:57 pm

1 stop6h 18m

Santo Domingo Las Americas

Mon 1/12

1:24 am-8:22 am

1 stop7h 58m

$414

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Mon 9/22

5:26 am-1:24 pm

2 stops30h 58m

Santo Domingo Las Americas

Fri 10/3

2:50 pm-5:34 pm

2 stops27h 44m

$6,889

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Sun 9/7

6:51 am-5:15 pm

1 stop9h 24m

$207

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Sat 1/3

8:48 am-4:12 pm

1 stop6h 24m

$306

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Cali to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Cali with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Santo Domingo

How far ahead should I book a flight from Cali to Santo Domingo?

The best time to book flights from Cali to Santo Domingo is 53 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Cali to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Cali to Santo Domingo (average of $362). Flying from Cali to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Cali to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Peruse reviews from past customers who have flown with Delta, Copa Airlines, and Avianca from Cali to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,977 reviews

Reviews

1 / 20

4.0

Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.

Delta

8.0

Very good

7,977 reviews

Delta

8.0

Very good

7,977 reviews

Reviews

1 / 20

4.0

Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.

Copa Airlines

7.5

Good

1,493 reviews

Delta

8.0

Very good

7,977 reviews

Reviews

1 / 20

4.0

Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.

Avianca

6.7

Okay

2,386 reviews

Delta

8.0

Very good

7,977 reviews

Reviews

1 / 20

4.0

Okay

Tony,Apr 2024

MCO - ATL

Terrible flight crew that skipped our row for service multiple times.

Related info for your journey

What are the cheapest airlines flying from Cali to Santo Domingo round-trip?
Flying on Copa Airlines is currently your cheapest option to Santo Domingo, with prices starting at $337. Additional round-trip tickets that might be worth considering are offered by Avianca and Delta, with the lowest prices starting at $349 and $6,889, respectively. Users have found that Copa Airlines is 6% cheaper than the other options available to this destination.
Can I find deals for flights from Cali to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Cali to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Cali to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Santo Domingo.
Can I find deals for business class flights from Cali to Santo Domingo?
Yes. Cheapflights offers flight deals from Cali to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Cali to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Cali to Santo Domingo (average of $362). Flying from Cali to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Cali to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time
Avianca	Cheapest$284	Average$365	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$308	Average$353	FlexibilityNo cancel fee	On-time70%

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$207+ Cheap flights from Cali (CLO) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Cali to Santo Domingo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Cali Alfonso B. Aragon Intl to Santo Domingo Las Americas are usually found in September or February, booked 53 days in advance, depart on a Friday or Wednesday and return on a Tuesday

Cheap flight deals from Cali to Santo Domingo

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Cali to Santo Domingo

Cheapest flights from Cali to Santo DomingoExplore the most affordable flight options available from Cali to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Explore the most affordable flight options available from Cali to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Cali to Santo Domingo that are best for you.

Best time to book a flight from Cali to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Cali with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Cali to Santo Domingo

How far ahead should I book a flight from Cali to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Cali to Santo Domingo. Price data was last updated on July 25, 2025.

What is the cheapest month to book a flight from Cali to Santo Domingo?

How much does it cost to fly round-trip from Cali to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Peruse reviews from past customers who have flown with Delta, Copa Airlines, and Avianca from Cali to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Cali to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Cali to Santo Domingo round-trip?

Can I find deals for flights from Cali to Santo Domingo that include hotel bookings?

How can I find direct flights from Cali to Santo Domingo?

Can I find deals for business class flights from Cali to Santo Domingo?

What is the cheapest month to book a flight from Cali to Santo Domingo?

Traveling to a place near Santo Domingo?

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Alternative routes for Cali to Santo Domingo

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Top 2 airlines flying from Cali to Santo Domingo

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Cheapest flights from Cali to Santo Domingo
Explore the most affordable flight options available from Cali to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.