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Santo Domingo

$205+ Cheap flights from Buffalo (BUF) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SDQ
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
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Cheap flight deals from Buffalo to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 20, 2025.

Round-trip from

$405
(Expedia)

One-way from

$205
(Priceline)

Popular in

February

Cheapest in

September

Average price

$438
From Buffalo to Santo Domingo Las Americas
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One-way flight from Buffalo to Santo Domingo Las Americas
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Highest demand for flights based on searches. 7% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Buffalo to Santo Domingo

Cheapest flights from Buffalo to Santo Domingo
Explore the most affordable flight options available from Buffalo to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This Expedia deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:40 amBUF - SDQ
1 stop6h 37mJetBlue
Fri 11/74:10 amSDQ - BUF
1 stop8h 09mJetBlue
Deal found 8/18$405
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:00 amBUF - SDQ
2 stops15h 46mUnited Airlines
Sat 11/84:18 pmSDQ - BUF
1 stop7h 40mUnited Airlines
Deal found 8/18$440
This JetBlue deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1512:00 pmBUF - SDQ
1 stop9h 23mJetBlue
Mon 1/510:40 pmSDQ - BUF
1 stop10h 49mJetBlue
Deal found 8/18$465
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:27 pmBUF - SDQ
2 stops18h 45mAmerican Airlines
Sat 11/83:11 pmSDQ - BUF
2 stops9h 57mAmerican Airlines
Deal found 8/18$473
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:51 amBUF - SDQ
2 stops14h 04mAmerican Airlines
Mon 1/57:35 pmSDQ - BUF
2 stops17h 19mAmerican Airlines
Deal found 8/19$712
This Expedia deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/181:20 pmBUF - SDQ
1 stop10h 06mJetBlue
Thu 12/255:05 pmSDQ - BUF
1 stop7h 50mJetBlue
Deal found 8/20$717
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:30 amBUF - SDQ
2 stops9h 20mAmerican Airlines
Mon 1/57:35 pmSDQ - BUF
2 stops17h 19mAmerican Airlines
Deal found 8/20$757
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:13 amBUF - SDQ
2 stops8h 27mAmerican Airlines
Sat 12/276:20 pmSDQ - BUF
2 stops17h 18mAmerican Airlines
Deal found 8/20$773
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:19 amBUF - SDQ
2 stops13h 36mAmerican Airlines
Tue 1/67:05 amSDQ - BUF
1 stop16h 21mAmerican Airlines
Deal found 8/20$777
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1910:20 amBUF - SDQ
2 stops15h 30mUnited Airlines
Fri 8/221:10 pmSDQ - BUF
2 stops20h 44mUnited Airlines
Deal found 8/18$813

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Buffalo

Fly to

Santo Domingo

Route

Depart

Return

Price

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 11/1

6:40 am-1:17 pm

1 stop6h 37m

Santo Domingo Las Americas

Fri 11/7

4:10 am-3:39 pm

1 stop12h 29m

$405

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 11/1

6:00 am-12:41 pm

1 stop6h 41m

Santo Domingo Las Americas

Sat 11/8

6:00 am-9:00 pm

2 stops16h 00m

$440

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 1/24

12:45 pm-3:54 am

1 stop14h 09m

Santo Domingo Las Americas

Sat 2/7

5:19 am-11:50 am

1 stop7h 31m

$464

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 1/24

8:20 pm-3:54 am

1 stop6h 34m

Santo Domingo Las Americas

Fri 2/6

4:27 pm-11:38 pm

1 stop8h 11m

$464

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 12/15

12:00 pm-10:23 pm

1 stop9h 23m

Santo Domingo Las Americas

Mon 1/5

10:40 pm-8:29 am

1 stop10h 49m

$465

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 9/17

3:55 pm-12:35 am

1 stop8h 40m

$205

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 9/17

8:00 am-8:30 pm

2 stops12h 30m

$222

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 1/24

4:00 pm-11:59 pm

1 stop6h 59m

$223

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 1/24

6:21 am-8:40 pm

2 stops13h 19m

$229

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 12/24

7:08 pm-11:40 am

2 stops39h 32m

$436

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/20

Showing 1-10 of 15 results
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Best time to book a flight from Buffalo to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Santo Domingo

What is the cheapest month to book a flight from Buffalo to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $362). Flying from Buffalo to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SDQ?

Find hourly flight availability from Buffalo to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 20, 2025.

It’s optimal to fly from Buffalo to Santo Domingo in the afternoon. By choosing this option you can save up to 18% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated August 20, 2025.
Peruse reviews from past customers who have flown with Delta and JetBlue from Buffalo to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,916 reviews
Delta
8.0
Very good
7,982 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Crew

8.5

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Santo Domingo?

    For as low as $405, JetBlue can have you in Santo Domingo from Buffalo in 6h 37m. The distance between Buffalo and Santo Domingo is about 1773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Buffalo to Santo Domingo round-trip?

    Currently priced at $422, JetBlue will fly you from Buffalo to Santo Domingo and back. In addition to JetBlue, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $432. You may be able to fly from Buffalo to Santo Domingo for 19% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Buffalo to Santo Domingo one-way?

    The cheapest airlines for a one-way flight from Buffalo to Santo Domingo are JetBlue ($205), American Airlines ($222), and Delta ($223).

  • Can I find deals for flights from Buffalo to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santo Domingo.

  • Can I find deals for business class flights from Buffalo to Santo Domingo?

    Yes. Cheapflights offers flight deals from Buffalo to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $362). Flying from Buffalo to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Buffalo to Santo Domingo

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Top 2 airlines flying from Buffalo to Santo Domingo

Discover the top 2 airlines that operate flights from Buffalo to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$422Average$533FlexibilityNo cancel feeOn-time62%
DeltaCheapest$432Average$604FlexibilityNo cancel feeOn-timeN/A

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