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Santo Domingo

$150+ Cheap flights from Buffalo (BUF) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SDQ
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
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Cheap flight deals from Buffalo to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$324
(JetBlue)

One-way from

$150
(American Airlines)

Popular in

February

Cheapest in

September

Average price

$534
Provider with most accurate pricing for Buffalo-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Santo Domingo Las Americas flights.
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From Buffalo to Santo Domingo Las Americas
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One-way flight from Buffalo to Santo Domingo Las Americas
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Highest demand for flights based on searches. 12% potential increase in price ($78 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Buffalo to Santo Domingo

Cheapest flights from Buffalo to Santo Domingo
Explore the most affordable flight options available from Buffalo to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This JetBlue deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/47:45 amBUF - SDQ
1 stop10h 09mJetBlue
Wed 11/129:59 amSDQ - BUF
1 stop12h 06mJetBlue
Deal found 10/21$324
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/83:57 pmBUF - SDQ
1 stop8h 30mDelta
Wed 11/126:45 amSDQ - BUF
1 stop13h 34mDelta
Deal found 10/21$328
This Expedia deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/221:53 pmBUF - SDQ
1 stop9h 43mJetBlue
Thu 1/89:45 amSDQ - BUF
1 stop12h 51mJetBlue
Deal found 10/21$342
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/911:19 amBUF - SDQ
1 stop13h 17mDelta
Sat 11/158:40 pmSDQ - BUF
1 stop14h 57mDelta
Deal found 10/21$353
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/93:45 pmBUF - SDQ
1 stop8h 51mDelta
Tue 11/118:40 pmSDQ - BUF
1 stop14h 57mDelta
Deal found 10/21$378
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:33 pmBUF - SDQ
2 stops21h 12mAmerican Airlines
Tue 11/116:00 amSDQ - BUF
2 stops18h 36mAmerican Airlines
Deal found 10/21$388
This JetBlue deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/47:45 amBUF - SDQ
1 stop10h 09mJetBlue
Sun 11/94:10 amSDQ - BUF
1 stop8h 09mJetBlue
Deal found 10/21$397
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/297:00 amBUF - SDQ
1 stop11h 24mDelta
Wed 11/58:49 pmSDQ - BUF
1 stop14h 42mDelta
Deal found 10/23$399
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:00 amBUF - SDQ
1 stop17h 27mDelta
Mon 11/108:40 pmSDQ - BUF
1 stop14h 57mDelta
Deal found 10/21$401
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/292:30 pmBUF - SDQ
2 stops18h 55mAmerican Airlines
Wed 11/53:05 pmSDQ - BUF
2 stops9h 21mAmerican Airlines
Deal found 10/23$402

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Buffalo

Fly to

Santo Domingo

Route

Depart

Return

Price

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 11/10

11:19 am-1:36 am

1 stop13h 17m

Santo Domingo Las Americas

Sat 11/15

8:40 pm-10:37 am

1 stop14h 57m

$328

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 1/17

5:17 pm-12:23 pm

2 stops18h 06m

Santo Domingo Las Americas

Fri 1/23

6:00 am-10:43 pm

2 stops17h 43m

$328

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 11/8

3:57 pm-1:27 am

1 stop8h 30m

Santo Domingo Las Americas

Sat 11/15

8:40 pm-10:37 am

1 stop14h 57m

$328

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 12/22

1:53 pm-12:36 am

1 stop9h 43m

Santo Domingo Las Americas

Thu 1/8

9:45 am-9:36 pm

1 stop12h 51m

$342

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 11/9

11:19 am-1:36 am

1 stop13h 17m

Santo Domingo Las Americas

Thu 11/13

6:45 am-3:05 pm

1 stop9h 20m

$353

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 11/9

11:19 am-1:36 am

1 stop13h 17m

Santo Domingo Las Americas

Sat 11/15

8:40 pm-10:37 am

1 stop14h 57m

$353

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 11/4

7:45 am-6:54 pm

1 stop10h 09m

Santo Domingo Las Americas

Tue 11/11

4:10 am-11:19 am

1 stop8h 09m

$356

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 11/10

7:00 am-7:08 pm

1 stop11h 08m

Santo Domingo Las Americas

Tue 11/11

8:40 pm-10:37 am

1 stop14h 57m

$378

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 10/29

7:00 am-6:24 pm

1 stop11h 24m

Santo Domingo Las Americas

Wed 11/5

8:49 pm-10:31 am

1 stop14h 42m

$399

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 10/29

7:00 am-10:46 pm

2 stops15h 46m

Santo Domingo Las Americas

Wed 11/5

4:18 pm-10:58 pm

1 stop7h 40m

$420

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/22

Showing 1-10 of 20 results
1
2

Compare providers for flights from Buffalo to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Santo Domingo in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Santo Domingo

What is the cheapest month to book a flight from Buffalo to Santo Domingo?

Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in April is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated October 23, 2025.
Peruse reviews from past customers who have flown with Delta and JetBlue from Buffalo to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,981 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
7,981 reviews
Delta
7.9
Good
7,981 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,908 reviews
Delta
7.9
Good
7,981 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Santo Domingo?

    For as low as $342, Delta can have you in Santo Domingo from Buffalo in 9h 43m. The distance between Buffalo and Santo Domingo is about 1773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Buffalo to Santo Domingo round-trip?

    Currently priced at $422, JetBlue will fly you from Buffalo to Santo Domingo and back. In addition to JetBlue, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $422. You may be able to fly from Buffalo to Santo Domingo for 20% less than the average price by searching for these airlines.

  • Can I find deals for flights from Buffalo to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santo Domingo.

  • Can I find deals for business class flights from Buffalo to Santo Domingo?

    Yes. Cheapflights offers flight deals from Buffalo to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Santo Domingo?

    Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in April is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 2 airlines flying from Buffalo to Santo Domingo

Discover the top 2 airlines that operate flights from Buffalo to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$422Average$604FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$422Average$535FlexibilityNo cancel feeOn-time62%

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