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Santo Domingo

$151+ Cheap flights from Buffalo (BUF) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SDQ
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Buffalo to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$319
(American Airlines)

One-way from

$151
(American Airlines)

Popular in

February

Cheapest in

March

Average price

$604
Provider with most accurate pricing for Buffalo-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Santo Domingo Las Americas flights.
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From Buffalo to Santo Domingo Las Americas
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One-way flight from Buffalo to Santo Domingo Las Americas
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Highest demand for flights based on searches. 10% potential increase in price ($61 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Buffalo to Santo Domingo

Cheapest flights from Buffalo to Santo Domingo
Explore the most affordable flight options available from Buffalo to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:14 amBUF - SDQ
2 stops10h 41mAmerican Airlines
Sat 5/24:00 pmSDQ - BUF
2 stops18h 18mAmerican Airlines
Deal found 1/6$319
This JetBlue deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/27:00 amBUF - SDQ
1 stop12h 25mJetBlue
Fri 2/63:19 pmSDQ - BUF
1 stop9h 28mJetBlue
Deal found 1/6$347
This JetBlue deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:00 amBUF - SDQ
1 stop7h 28mJetBlue
Wed 2/2511:20 amSDQ - BUF
1 stop8h 20mJetBlue
Deal found 1/6$371
This Priceline deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/106:33 pmBUF - SDQ
1 stop14h 08mFrontier
Sat 1/175:12 pmSDQ - BUF
1 stop17h 09mFrontier
Deal found 1/7$411
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 amBUF - SDQ
1 stop8h 10mUnited Airlines
Sat 5/21:10 pmSDQ - BUF
2 stops10h 16mUnited Airlines
Deal found 1/6$415
This Delta deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1811:51 amBUF - SDQ
1 stop11h 39mDelta
Wed 1/218:45 pmSDQ - BUF
1 stop15h 26mDelta
Deal found 1/6$420
This Priceline deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/178:06 pmBUF - SDQ
1 stop12h 48mFrontier
Tue 1/202:40 pmSDQ - BUF
2 stops47h 04mFrontier
Deal found 1/6$421
This Priceline deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:00 amBUF - SDQ
1 stop8h 21mJetBlue
Sun 3/227:50 pmSDQ - BUF
1 stop13h 14mJetBlue
Deal found 1/5$424
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/168:58 pmBUF - SDQ
1 stop15h 24mMultiple Airlines
Wed 1/2112:52 pmSDQ - BUF
2 stops24h 52mMultiple Airlines
Deal found 1/6$425
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/135:12 amBUF - SDQ
2 stops11h 17mAmerican Airlines
Fri 1/164:47 pmSDQ - BUF
2 stops20h 11mAmerican Airlines
Deal found 1/6$431
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/135:12 amBUF - SDQ
2 stops11h 17mAmerican Airlines
Sun 1/184:47 pmSDQ - BUF
2 stops19h 34mAmerican Airlines
Deal found 1/6$436
This Priceline deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:00 amBUF - SDQ
2 stops21h 31mMultiple Airlines
Mon 3/3010:56 amSDQ - BUF
1 stop9h 34mMultiple Airlines
Deal found 1/7$450

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Buffalo

Fly to

Santo Domingo

Route

Depart

Return

Price

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 2/2

7:00 am-8:25 pm

1 stop12h 25m

Santo Domingo Las Americas

Fri 2/6

9:50 pm-9:02 am

1 stop12h 12m

$347

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Thu 2/19

6:00 am-2:28 pm

1 stop7h 28m

Santo Domingo Las Americas

Wed 2/25

11:20 am-6:40 pm

1 stop8h 20m

$371

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Thu 3/26

7:00 am-6:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Mon 3/30

8:25 pm-10:57 am

1 stop14h 32m

$420

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 1/18

11:51 am-12:30 am

1 stop11h 39m

Santo Domingo Las Americas

Wed 1/21

8:45 pm-11:11 am

1 stop15h 26m

$420

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Fri 1/16

8:58 pm-1:22 pm

1 stop15h 24m

Santo Domingo Las Americas

Wed 1/21

12:52 pm-12:44 pm

2 stops24h 52m

$425

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 1/13

5:12 am-5:29 pm

2 stops11h 17m

Santo Domingo Las Americas

Fri 1/16

4:47 pm-11:58 am

2 stops20h 11m

$431

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 1/18

6:00 am-2:14 pm

1 stop7h 14m

Santo Domingo Las Americas

Tue 1/20

6:01 am-2:30 pm

1 stop9h 29m

$453

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 1/17

5:16 am-5:29 pm

2 stops11h 13m

Santo Domingo Las Americas

Sun 1/18

6:29 pm-11:21 am

2 stops17h 52m

$456

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Thu 1/15

2:10 pm-2:14 pm

1 stop23h 04m

Santo Domingo Las Americas

Sun 1/25

8:59 pm-9:02 am

1 stop13h 03m

$458

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 2/17

3:00 pm-1:29 am

1 stop9h 29m

Santo Domingo Las Americas

Mon 2/23

10:35 pm-9:35 am

1 stop12h 00m

$461

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/6

Showing 1-10 of 16 results
1
2

Compare providers for flights from Buffalo to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Santo Domingo in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
OvagoPrice Accuracy2 starsTrust Score*2 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Santo Domingo

What is the cheapest month to book a flight from Buffalo to Santo Domingo?

Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated January 8, 2026.
Peruse reviews from past customers who have flown with Delta and JetBlue from Buffalo to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,032 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,032 reviews
Delta
7.9
Good
8,032 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,892 reviews
Delta
7.9
Good
8,032 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Santo Domingo?

    For as low as $420, JetBlue can have you in Santo Domingo from Buffalo in 11h 55m. The distance between Buffalo and Santo Domingo is about 1773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Buffalo to Santo Domingo round-trip?

    Currently priced at $394, Delta will fly you from Buffalo to Santo Domingo and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on JetBlue for as low as $422. You may be able to fly from Buffalo to Santo Domingo for 25% less than the average price by searching for these airlines.

  • Can I find deals for flights from Buffalo to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santo Domingo.

  • Can I find deals for business class flights from Buffalo to Santo Domingo?

    Yes. Cheapflights offers flight deals from Buffalo to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Santo Domingo?

    Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 2 airlines flying from Buffalo to Santo Domingo

Discover the top 2 airlines that operate flights from Buffalo to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$394Average$469FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$422Average$564FlexibilityNo cancel feeOn-time62%

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