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Santo Domingo

$163+ Cheap flights from Buffalo (BUF) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SDQ
Dec 24 — Dec 311
Wed 12/24
Wed 12/31
1 adult, Economy
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Cheap flight deals from Buffalo to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$342
(American Airlines)

One-way from

$163
(American Airlines)

Popular in

February

Cheapest in

March

Average price

$520
Provider with most accurate pricing for Buffalo-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Santo Domingo Las Americas flights.
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From Buffalo to Santo Domingo Las Americas
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One-way flight from Buffalo to Santo Domingo Las Americas
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Highest demand for flights based on searches. 7% potential increase in price ($41 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Buffalo to Santo Domingo

Cheapest flights from Buffalo to Santo Domingo
Explore the most affordable flight options available from Buffalo to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 24, 2025.

This JetBlue deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/158:00 amBUF - SDQ
1 stop9h 54mJetBlue
Tue 1/69:43 amSDQ - BUF
1 stop10h 06mJetBlue
Deal found 11/23$342
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:35 pmBUF - SDQ
2 stops16h 53mAmerican Airlines
Wed 12/101:28 pmSDQ - BUF
2 stops10h 29mAmerican Airlines
Deal found 11/23$375
This Delta deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:00 amBUF - SDQ
1 stop7h 42mDelta
Wed 12/103:57 pmSDQ - BUF
1 stop9h 02mDelta
Deal found 11/23$408
This SmartFares deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:00 pmBUF - SDQ
1 stop8h 22mJetBlue
Tue 12/94:10 amSDQ - BUF
1 stop8h 23mJetBlue
Deal found 11/23$450
This Kiwi.com deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:47 pmBUF - SDQ
1 stop12h 45mMultiple Airlines
Fri 1/164:40 pmSDQ - BUF
2 stops27h 31mMultiple Airlines
Deal found 11/23$456
This American Airlines deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:35 pmBUF - SDQ
2 stops20h 23mAmerican Airlines
Wed 1/146:00 amSDQ - BUF
2 stops17h 55mAmerican Airlines
Deal found 11/23$458
This Justfly.com deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:14 pmBUF - SDQ
1 stop12h 38mFrontier
Sun 12/284:33 pmSDQ - BUF
1 stop25h 12mFrontier
Deal found 11/22$459
This Priceline deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:43 amBUF - SDQ
1 stop23h 37mFrontier
Mon 12/2912:35 pmSDQ - BUF
1 stop9h 33mFrontier
Deal found 11/22$464
This Priceline deal was found by Cheapflights users on 11/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1211:30 amBUF - SDQ
2 stops21h 12mFrontier
Wed 12/1710:26 amSDQ - BUF
2 stops27h 46mFrontier
Deal found 11/22$466
This Priceline deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/182:07 pmBUF - SDQ
1 stop20h 13mFrontier
Thu 1/1511:09 amSDQ - BUF
1 stop9h 54mFrontier
Deal found 11/23$484
This Priceline deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/182:07 pmBUF - SDQ
1 stop22h 31mFrontier
Sun 1/1811:09 amSDQ - BUF
1 stop9h 54mFrontier
Deal found 11/23$498

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Buffalo

Fly to

Santo Domingo

Route

Depart

Return

Price

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 12/15

6:45 am-2:22 pm

1 stop6h 37m

Santo Domingo Las Americas

Mon 1/5

4:05 am-2:30 pm

1 stop11h 25m

$344

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Fri 12/5

6:35 pm-12:28 pm

2 stops16h 53m

Santo Domingo Las Americas

Wed 12/10

1:28 pm-10:57 pm

2 stops10h 29m

$375

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Fri 12/5

6:00 am-2:42 pm

1 stop7h 42m

Santo Domingo Las Americas

Wed 12/10

3:57 pm-11:59 pm

1 stop9h 02m

$408

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 1/12

3:25 pm-4:34 am

1 stop12h 09m

Santo Domingo Las Americas

Mon 1/26

6:00 am-6:50 pm

1 stop13h 50m

$423

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 1/18

8:30 am-11:46 pm

2 stops14h 16m

Santo Domingo Las Americas

Mon 2/2

2:53 pm-10:31 pm

1 stop8h 38m

$428

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 12/30

1:47 pm-3:32 am

1 stop12h 45m

Santo Domingo Las Americas

Fri 1/16

4:40 pm-7:11 pm

2 stops27h 31m

$456

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 1/18

6:00 am-2:14 pm

1 stop7h 14m

Santo Domingo Las Americas

Sat 1/31

4:15 am-11:47 pm

1 stop20h 32m

$462

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 12/22

10:43 am-11:20 am

1 stop23h 37m

Santo Domingo Las Americas

Mon 12/29

12:35 pm-9:08 pm

1 stop9h 33m

$464

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 12/15

2:46 pm-8:34 am

1 stop16h 48m

Santo Domingo Las Americas

Thu 1/22

6:00 am-6:50 pm

1 stop13h 50m

$523

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Fri 12/5

6:00 am-1:41 pm

1 stop6h 41m

Santo Domingo Las Americas

Wed 12/10

2:53 pm-9:48 am

2 stops19h 55m

$555

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Showing 1-10 of 21 results
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Compare providers for flights from Buffalo to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Santo Domingo in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Santo Domingo

What is the cheapest month to book a flight from Buffalo to Santo Domingo?

Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated November 24, 2025.
Peruse reviews from past customers who have flown with Delta and JetBlue from Buffalo to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,993 reviews

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
7,993 reviews
Delta
7.9
Good
7,993 reviews

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,903 reviews
Delta
7.9
Good
7,993 reviews

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Santo Domingo?

    For as low as $344, JetBlue can have you in Santo Domingo from Buffalo in 6h 37m. The distance between Buffalo and Santo Domingo is about 1773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Buffalo to Santo Domingo round-trip?

    Currently priced at $422, JetBlue will fly you from Buffalo to Santo Domingo and back. In addition to JetBlue, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $422. You may be able to fly from Buffalo to Santo Domingo for 19% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Buffalo to Santo Domingo one-way?

    The cheapest airlines for a one-way flight from Buffalo to Santo Domingo are Frontier ($254), American Airlines ($260), and JetBlue ($271).

  • Can I find deals for flights from Buffalo to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santo Domingo.

  • Can I find deals for business class flights from Buffalo to Santo Domingo?

    Yes. Cheapflights offers flight deals from Buffalo to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Santo Domingo?

    Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Buffalo to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Santo Domingo flights
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LaGuardia to Punta Cana flights
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John F Kennedy Intl to La Romana flights
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Albany to Santo Domingo flights
White Plains to Santo Domingo flights
Syracuse to Puerto Plata flights
Rochester to Santo Domingo flights
Buffalo to Puerto Plata flights
Syracuse to Santiago de los Caballeros flights
Albany to Santiago de los Caballeros flights
Newark to Nagua flights
LaGuardia to Nagua flights
Rochester to Puerto Plata flights
Albany to Puerto Plata flights
Rochester to La Romana flights
Buffalo to Santiago de los Caballeros flights
Stewart to Santo Domingo flights
Stewart to Santiago de los Caballeros flights
Islip to Santiago de los Caballeros flights
Buffalo to La Romana flights
Stewart to Puerto Plata flights
Niagara Falls to Punta Cana flights
Islip to Puerto Plata flights

Top 2 airlines flying from Buffalo to Santo Domingo

Discover the top 2 airlines that operate flights from Buffalo to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$422Average$604FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$422Average$529FlexibilityNo cancel feeOn-time62%

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