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Santo Domingo

$235+ Cheap flights from Buffalo (BUF) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SDQ
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Buffalo to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$357
(Flysmarter)

One-way from

$235
(Justfly.com)

Popular in

February

Cheapest in

August

Average price

$432
From Buffalo to Santo Domingo Las Americas
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One-way flight from Buffalo to Santo Domingo Las Americas
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Highest demand for flights based on searches. 11% potential increase in price ($69 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Buffalo to Santo Domingo

Cheapest flights from Buffalo to Santo Domingo
Explore the most affordable flight options available from Buffalo to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Flysmarter deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:00 amBUF - SDQ
1 stop7h 19mJetBlue
Thu 11/63:45 pmSDQ - BUF
1 stop7h 42mJetBlue
Deal found 9/15$357
This SmartFares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/82:49 pmBUF - SDQ
1 stop11h 51mJetBlue
Tue 11/114:59 amSDQ - BUF
1 stop7h 36mJetBlue
Deal found 9/14$373
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:14 amBUF - SDQ
2 stops9h 31mAmerican Airlines
Thu 11/66:24 pmSDQ - BUF
1 stop18h 24mAmerican Airlines
Deal found 9/15$402
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:40 amBUF - SDQ
2 stops15h 05mAmerican Airlines
Wed 11/126:00 amSDQ - BUF
2 stops10h 56mAmerican Airlines
Deal found 9/14$411
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:30 pmBUF - SDQ
2 stops17h 11mUnited Airlines
Wed 11/124:18 pmSDQ - BUF
1 stop7h 40mUnited Airlines
Deal found 9/14$452
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:00 amBUF - SDQ
2 stops14h 30mAmerican Airlines
Mon 9/227:00 amSDQ - BUF
2 stops14h 51mAmerican Airlines
Deal found 9/14$486
This JetBlue deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2111:45 amBUF - SDQ
1 stop14h 12mJetBlue
Mon 11/244:09 amSDQ - BUF
1 stop7h 53mJetBlue
Deal found 9/14$509
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:00 amBUF - SDQ
2 stops16h 45mAmerican Airlines
Tue 11/256:14 pmSDQ - BUF
2 stops17h 48mAmerican Airlines
Deal found 9/14$621

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Buffalo

Fly to

Santo Domingo

Route

Depart

Return

Price

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 11/8

2:49 pm-3:40 am

1 stop11h 51m

Santo Domingo Las Americas

Tue 11/11

4:59 am-11:35 am

1 stop7h 36m

$373

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 3/1

2:29 pm-4:31 am

1 stop13h 02m

Santo Domingo Las Americas

Wed 3/4

2:35 am-11:50 am

1 stop10h 15m

$387

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 2/3

6:00 am-3:17 pm

1 stop8h 17m

Santo Domingo Las Americas

Tue 2/10

4:27 pm-11:38 pm

1 stop8h 11m

$387

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 3/3

9:20 pm-10:03 am

1 stop11h 43m

Santo Domingo Las Americas

Thu 3/5

11:30 am-8:21 pm

1 stop9h 51m

$387

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 2/3

6:42 am-8:40 pm

2 stops12h 58m

Santo Domingo Las Americas

Tue 2/10

8:50 am-10:49 pm

2 stops14h 59m

$402

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 11/8

7:30 pm-1:41 pm

2 stops17h 11m

Santo Domingo Las Americas

Wed 11/12

4:18 pm-10:58 pm

1 stop7h 40m

$452

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 12/21

6:30 am-11:46 pm

2 stops16h 16m

$1,065

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Buffalo to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Santo Domingo

What is the cheapest month to book a flight from Buffalo to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $362). Flying from Buffalo to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SDQ?

Find hourly flight availability from Buffalo to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

It’s optimal to fly from Buffalo to Santo Domingo in the afternoon. By choosing this option you can save up to 18% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated September 16, 2025.
Peruse reviews from past customers who have flown with Delta and JetBlue from Buffalo to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,912 reviews
Delta
8.0
Very good
7,954 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Santo Domingo?

    For as low as $373, JetBlue can have you in Santo Domingo from Buffalo in 11h 51m. The distance between Buffalo and Santo Domingo is about 1773 mi.

  • What are the cheapest airlines flying from Buffalo to Santo Domingo round-trip?

    Currently priced at $422, JetBlue will fly you from Buffalo to Santo Domingo and back. In addition to JetBlue, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $432. You may be able to fly from Buffalo to Santo Domingo for 20% less than the average price by searching for these airlines.

  • Can I find deals for flights from Buffalo to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santo Domingo.

  • Can I find deals for business class flights from Buffalo to Santo Domingo?

    Yes. Cheapflights offers flight deals from Buffalo to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $362). Flying from Buffalo to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Buffalo to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Buffalo to Santo Domingo

Discover the top 2 airlines that operate flights from Buffalo to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$422Average$525FlexibilityNo cancel feeOn-time62%
DeltaCheapest$432Average$604FlexibilityNo cancel feeOn-timeN/A

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