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Santo Domingo

$133+ Cheap flights from Buffalo (BUF) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SDQ
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheap flight deals from Buffalo to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$342
(Delta)

One-way from

$133
(Trip.com)

Popular in

February

Cheapest in

March

Average price

$520
Provider with most accurate pricing for Buffalo-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Santo Domingo Las Americas flights.
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From Buffalo to Santo Domingo Las Americas
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One-way flight from Buffalo to Santo Domingo Las Americas
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Highest demand for flights based on searches. 7% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Buffalo to Santo Domingo

Cheapest flights from Buffalo to Santo Domingo
Explore the most affordable flight options available from Buffalo to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This JetBlue deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/88:00 amBUF - SDQ
1 stop10h 00mJetBlue
Wed 12/103:28 pmSDQ - BUF
1 stop7h 44mJetBlue
Deal found 11/13$390
This Expedia deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/82:46 pmBUF - SDQ
1 stop16h 48mJetBlue
Mon 12/157:01 pmSDQ - BUF
1 stop17h 32mJetBlue
Deal found 11/10$461
This Expedia deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1912:15 pmBUF - SDQ
1 stop12h 38mJetBlue
Tue 12/29:46 amSDQ - BUF
1 stop12h 45mJetBlue
Deal found 11/13$504
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:05 amBUF - SDQ
2 stops17h 45mAmerican Airlines
Mon 12/156:23 pmSDQ - BUF
2 stops17h 51mAmerican Airlines
Deal found 11/10$554
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:00 amBUF - SDQ
1 stop6h 41mUnited Airlines
Tue 12/22:53 pmSDQ - BUF
2 stops23h 19mUnited Airlines
Deal found 11/13$560
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:40 pmBUF - SDQ
2 stops32h 52mMultiple Airlines
Wed 12/318:20 amSDQ - BUF
1 stop13h 20mMultiple Airlines
Deal found 11/10$561
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:33 pmBUF - SDQ
2 stops16h 46mAmerican Airlines
Tue 12/26:00 amSDQ - BUF
2 stops18h 26mAmerican Airlines
Deal found 11/13$572
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/182:07 pmBUF - SDQ
2 stops11h 47mMultiple Airlines
Fri 12/268:20 amSDQ - BUF
1 stop13h 20mMultiple Airlines
Deal found 11/11$582

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Buffalo

Fly to

Santo Domingo

Route

Depart

Return

Price

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 3/1

7:00 am-11:59 pm

1 stop15h 59m

Santo Domingo Las Americas

Thu 3/5

8:00 pm-11:11 am

1 stop16h 11m

$342

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 1/26

6:25 am-2:39 pm

1 stop7h 14m

Santo Domingo Las Americas

Thu 2/5

9:45 am-9:36 pm

1 stop12h 51m

$378

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 12/8

8:00 am-7:00 pm

1 stop10h 00m

Santo Domingo Las Americas

Wed 12/10

3:28 pm-10:12 pm

1 stop7h 44m

$390

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 3/17

6:00 am-12:41 pm

1 stop6h 41m

Santo Domingo Las Americas

Tue 3/24

5:00 am-7:06 pm

2 stops14h 06m

$394

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 3/1

5:30 am-11:59 pm

2 stops17h 29m

Santo Domingo Las Americas

Thu 3/5

3:19 pm-11:05 am

2 stops20h 46m

$563

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Thu 12/18

2:07 pm-2:54 am

2 stops11h 47m

Santo Domingo Las Americas

Sat 12/27

3:23 pm-12:36 pm

1 stop22h 13m

$594

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 12/21

6:32 pm-3:32 am

2 stops32h 00m

Santo Domingo Las Americas

Fri 12/26

8:20 am-8:40 pm

1 stop13h 20m

$605

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Fri 12/19

9:42 am-3:32 am

1 stop16h 50m

Santo Domingo Las Americas

Mon 12/29

12:35 pm-12:52 pm

1 stop25h 17m

$655

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Fri 12/19

9:42 am-2:54 am

2 stops16h 12m

Santo Domingo Las Americas

Sat 12/27

3:23 pm-12:36 pm

1 stop22h 13m

$685

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 12/31

12:50 pm-11:59 pm

2 stops10h 09m

Santo Domingo Las Americas

Wed 1/7

1:23 pm-10:40 pm

2 stops10h 17m

$702

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 19 results
1
2

Compare providers for flights from Buffalo to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Santo Domingo in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Santo Domingo

What is the cheapest month to book a flight from Buffalo to Santo Domingo?

Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in April is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated November 13, 2025.
Peruse reviews from past customers who have flown with Delta and JetBlue from Buffalo to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,906 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Santo Domingo?

    For as low as $394, Delta can have you in Santo Domingo from Buffalo in 6h 41m. The distance between Buffalo and Santo Domingo is about 1773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Buffalo to Santo Domingo round-trip?

    Currently priced at $422, JetBlue will fly you from Buffalo to Santo Domingo and back. In addition to JetBlue, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $422. You may be able to fly from Buffalo to Santo Domingo for 18% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Buffalo to Santo Domingo one-way?

    The cheapest airlines for a one-way flight from Buffalo to Santo Domingo are Frontier ($133), Delta ($152), and American Airlines ($175).

  • Can I find deals for flights from Buffalo to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santo Domingo.

  • Can I find deals for business class flights from Buffalo to Santo Domingo?

    Yes. Cheapflights offers flight deals from Buffalo to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Santo Domingo?

    Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in April is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Buffalo to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Buffalo to Santo Domingo

Discover the top 2 airlines that operate flights from Buffalo to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$422Average$604FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$422Average$529FlexibilityNo cancel feeOn-time62%

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