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Santo Domingo

$145+ Cheap flights from Buffalo (BUF) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/17. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SDQ
Jan 8 — Jan 151
Thu 1/8
Thu 1/15
1 adult, Economy
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Cheap flight deals from Buffalo to Santo Domingo

Cheapest flights from Buffalo to Santo Domingo
Explore the most affordable flight options available from Buffalo to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 9, 2025.

This JetBlue deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/181:55 pmBUF - SDQ
1 stop9h 43mJetBlue
Mon 1/56:01 amSDQ - BUF
1 stop11h 11mJetBlue
Deal found 12/9$319
This JetBlue deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:05 amBUF - SDQ
1 stop9h 53mJetBlue
Mon 1/510:40 pmSDQ - BUF
1 stop11h 56mJetBlue
Deal found 12/9$460
This Faresmojo deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:12 amBUF - SDQ
1 stop12h 46mJetBlue
Tue 1/139:43 amSDQ - BUF
1 stop10h 06mJetBlue
Deal found 12/7$535
This JetBlue deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:00 pmBUF - SDQ
1 stop8h 22mJetBlue
Sun 12/213:28 pmSDQ - BUF
1 stop9h 15mJetBlue
Deal found 12/9$630
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/281:37 pmBUF - SDQ
1 stop23h 01mMultiple Airlines
Tue 1/134:40 pmSDQ - BUF
2 stops41h 41mMultiple Airlines
Deal found 12/7$631
This JetBlue deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1712:19 pmBUF - SDQ
1 stop11h 05mJetBlue
Mon 1/56:01 amSDQ - BUF
1 stop14h 27mJetBlue
Deal found 12/8$650
This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:22 pmBUF - SDQ
2 stops15h 45mAmerican Airlines
Thu 1/226:00 amSDQ - BUF
2 stops17h 55mAmerican Airlines
Deal found 12/7$657
This Frontier deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/231:47 pmBUF - SDQ
2 stops18h 39mFrontier
Sat 12/2711:16 amSDQ - BUF
1 stop10h 34mFrontier
Deal found 12/9$714
This JetBlue deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/221:55 pmBUF - SDQ
1 stop9h 43mJetBlue
Thu 1/226:01 amSDQ - BUF
1 stop13h 46mJetBlue
Deal found 12/8$730

Find flight deals from Buffalo to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 9, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$318
(American Airlines)

One-way from

$145
(American Airlines)

Popular in

February

Cheapest in

March

Average price

$725
Provider with most accurate pricing for Buffalo-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Santo Domingo Las Americas flights.
Search Deals
From Buffalo to Santo Domingo Las Americas
Search Deals
One-way flight from Buffalo to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Buffalo

Fly to

Santo Domingo

Route

Depart

Return

Price

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Fri 1/23

5:12 am-10:39 pm

2 stops16h 27m

Santo Domingo Las Americas

Fri 1/30

6:00 am-9:06 pm

2 stops16h 06m

$318

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 1/24

6:32 pm-2:00 pm

2 stops18h 28m

Santo Domingo Las Americas

Sat 1/31

6:29 pm-12:08 pm

2 stops18h 39m

$318

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Thu 4/23

12:50 pm-1:14 am

1 stop12h 24m

Santo Domingo Las Americas

Mon 4/27

10:28 am-11:41 pm

1 stop13h 13m

$346

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 4/29

12:25 pm-7:34 pm

1 stop7h 09m

Santo Domingo Las Americas

Tue 5/5

1:40 am-11:29 am

1 stop9h 49m

$346

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sun 2/1

3:25 pm-4:35 am

1 stop12h 10m

Santo Domingo Las Americas

Thu 2/5

6:01 am-2:30 pm

1 stop9h 29m

$346

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 3/7

7:30 pm-3:58 am

1 stop7h 28m

Santo Domingo Las Americas

Thu 3/12

7:50 pm-9:04 am

1 stop13h 14m

$370

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Sat 1/24

7:00 am-7:49 pm

1 stop11h 49m

Santo Domingo Las Americas

Sat 1/31

6:01 am-6:47 pm

1 stop13h 46m

$370

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 1/21

10:45 am-11:46 pm

2 stops12h 01m

Santo Domingo Las Americas

Wed 1/28

6:00 am-8:29 pm

2 stops15h 29m

$378

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 1/21

7:00 am-7:49 pm

1 stop11h 49m

Santo Domingo Las Americas

Wed 1/28

9:50 pm-9:02 am

1 stop12h 12m

$395

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Fri 1/23

1:39 pm-3:29 pm

1 stop24h 50m

Santo Domingo Las Americas

Fri 1/30

9:34 pm-12:44 pm

2 stops40h 10m

$407

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/7

Showing 1-10 of 19 results
1
2

Compare providers for flights from Buffalo to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Santo Domingo in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
OvagoPrice Accuracy2 starsTrust Score*2 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Santo Domingo

What is the cheapest month to book a flight from Buffalo to Santo Domingo?

Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated December 9, 2025.
Peruse reviews from past customers who have flown with Delta and JetBlue from Buffalo to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,009 reviews
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,899 reviews
Delta
7.9
Good
8,009 reviews

Entertainment

7.9

Crew

8.5

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Santo Domingo?

    For as low as $346, American Airlines can have you in Santo Domingo from Buffalo in 12h 24m. The distance between Buffalo and Santo Domingo is about 1773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Buffalo to Santo Domingo round-trip?

    Currently priced at $394, Delta will fly you from Buffalo to Santo Domingo and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on JetBlue for as low as $422. You may be able to fly from Buffalo to Santo Domingo for 25% less than the average price by searching for these airlines.

  • Can I find deals for flights from Buffalo to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santo Domingo.

  • Can I find deals for business class flights from Buffalo to Santo Domingo?

    Yes. Cheapflights offers flight deals from Buffalo to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Santo Domingo?

    Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Buffalo to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Rochester to Puerto Plata flights
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Stewart to Santiago de los Caballeros flights
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Top 2 airlines flying from Buffalo to Santo Domingo

Discover the top 2 airlines that operate flights from Buffalo to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$394Average$469FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$422Average$553FlexibilityNo cancel feeOn-time62%

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