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Santo Domingo

$158+ Cheap flights from Buffalo (BUF) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SDQ
dic. 6 — dic. 131
sáb. 12/6
sáb. 12/13
1 adult, Economy
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Cheap flight deals from Buffalo to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated noviembre 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$328
(American Airlines)

One-way from

$158
(American Airlines)

Popular in

February

Cheapest in

September

Average price

$474
Provider with most accurate pricing for Buffalo-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Santo Domingo Las Americas flights.
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From Buffalo to Santo Domingo Las Americas
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One-way flight from Buffalo to Santo Domingo Las Americas
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Highest demand for flights based on searches. 11% potential increase in price ($65 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Buffalo to Santo Domingo

Cheapest flights from Buffalo to Santo Domingo
Explore the most affordable flight options available from Buffalo to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 6, 2025.

This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/36:35 pmBUF - SDQ
2 stops16h 53mAmerican Airlines
mié. 12/101:28 pmSDQ - BUF
2 stops10h 23mAmerican Airlines
Deal found 11/5$328
This Expedia deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/312:18 pmBUF - SDQ
1 stop11h 06mJetBlue
mié. 12/103:28 pmSDQ - BUF
1 stop7h 44mJetBlue
Deal found 11/5$374
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/1212:37 pmBUF - SDQ
2 stops22h 14mMultiple Airlines
lun. 12/222:53 pmSDQ - BUF
1 stop22h 59mMultiple Airlines
Deal found 11/5$393
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/157:30 pmBUF - SDQ
2 stops18h 36mUnited Airlines
mar. 12/234:18 pmSDQ - BUF
2 stops18h 28mUnited Airlines
Deal found 11/5$445
This JetBlue deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/1510:08 amBUF - SDQ
1 stop13h 41mJetBlue
mar. 12/2310:05 amSDQ - BUF
1 stop13h 36mJetBlue
Deal found 11/5$504
This JetBlue deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/176:45 amBUF - SDQ
1 stop6h 37mJetBlue
dom. 12/2110:05 amSDQ - BUF
1 stop13h 36mJetBlue
Deal found 11/5$513
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/36:00 amBUF - SDQ
1 stop6h 41mUnited Airlines
mié. 12/106:00 amSDQ - BUF
2 stops11h 53mUnited Airlines
Deal found 11/5$541
This JetBlue deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/1510:08 amBUF - SDQ
1 stop13h 41mJetBlue
lun. 12/111:54 pmSDQ - BUF
1 stop12h 39mJetBlue
Deal found 11/5$550
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/205:49 pmBUF - SDQ
2 stops40h 31mFrontier
sáb. 12/273:23 pmSDQ - BUF
1 stop22h 13mFrontier
Deal found 11/5$569
This Gotogate deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/1211:30 amBUF - SDQ
2 stops21h 12mFrontier
lun. 12/228:42 pmSDQ - BUF
2 stops48h 58mFrontier
Deal found 11/5$585

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Buffalo

Fly to

Santo Domingo

Route

Depart

Return

Price

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

jue. 1/15

6:53 pm-2:00 pm

2 stops18h 07m

Santo Domingo Las Americas

jue. 1/22

3:00 pm-11:41 pm

2 stops9h 41m

$332

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

dom. 3/1

11:51 am-11:59 pm

1 stop11h 08m

Santo Domingo Las Americas

jue. 3/5

8:00 pm-11:11 am

1 stop16h 11m

$342

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

mié. 12/3

12:18 pm-12:24 am

1 stop11h 06m

Santo Domingo Las Americas

mié. 12/10

3:28 pm-10:12 pm

1 stop7h 44m

$374

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

sáb. 3/28

9:20 pm-9:03 am

1 stop11h 43m

Santo Domingo Las Americas

mar. 4/7

4:05 am-2:25 pm

1 stop10h 20m

$388

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

jue. 1/15

11:51 am-7:14 pm

1 stop6h 23m

Santo Domingo Las Americas

jue. 1/22

7:31 am-12:16 am

1 stop17h 45m

$423

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

mié. 12/17

6:45 am-2:22 pm

1 stop6h 37m

Santo Domingo Las Americas

dom. 12/21

10:05 am-10:41 pm

1 stop13h 36m

$513

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

dom. 3/1

5:30 am-11:59 pm

2 stops17h 29m

Santo Domingo Las Americas

jue. 3/5

11:02 am-11:20 pm

2 stops13h 18m

$529

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

mié. 12/3

6:00 am-1:41 pm

1 stop6h 41m

Santo Domingo Las Americas

mié. 12/10

6:00 am-4:53 pm

2 stops11h 53m

$541

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

dom. 3/1

6:00 am-1:41 pm

1 stop6h 41m

Santo Domingo Las Americas

jue. 3/5

2:53 pm-11:46 pm

2 stops9h 53m

$552

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

mié. 12/31

3:49 pm-3:09 am

1 stop10h 20m

$177

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 21 results
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Compare providers for flights from Buffalo to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Santo Domingo in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Santo Domingo

What is the cheapest month to book a flight from Buffalo to Santo Domingo?

Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in April is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated noviembre 6, 2025.
Peruse reviews from past customers who have flown with Delta and JetBlue from Buffalo to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,004 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
8,004 reviews
Delta
7.9
Good
8,004 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
JetBlue
7.2
Good
2,907 reviews
Delta
7.9
Good
8,004 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Santo Domingo?

    For as low as $374, American Airlines can have you in Santo Domingo from Buffalo in 11h 06m. The distance between Buffalo and Santo Domingo is about 1773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Buffalo to Santo Domingo round-trip?

    Currently priced at $422, JetBlue will fly you from Buffalo to Santo Domingo and back. In addition to JetBlue, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $422. You may be able to fly from Buffalo to Santo Domingo for 18% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Buffalo to Santo Domingo one-way?

    The cheapest airlines for a one-way flight from Buffalo to Santo Domingo are Delta ($177), Frontier ($213), and JetBlue ($243).

  • Can I find deals for flights from Buffalo to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santo Domingo.

  • Can I find deals for business class flights from Buffalo to Santo Domingo?

    Yes. Cheapflights offers flight deals from Buffalo to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Santo Domingo?

    Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in April is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Buffalo to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Rochester to La Romana flights
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Islip to Santiago de los Caballeros flights
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Top 2 airlines flying from Buffalo to Santo Domingo

Discover the top 2 airlines that operate flights from Buffalo to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$422Average$604FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$422Average$529FlexibilityNo cancel feeOn-time62%

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