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Santo Domingo

$146+ Cheap flights from Buffalo (BUF) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SDQ
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Buffalo to Santo Domingo

Cheapest flights from Buffalo to Santo Domingo
Explore the most affordable flight options available from Buffalo to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
BUF
-
SDQ
2 stops16h 52m
American Airlines
Mon 5/186:00 am
SDQ
-
BUF
2 stops17h 50m
American Airlines
Deal found 1/25$319
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:00 am
BUF
-
SDQ
1 stop16h 32m
Delta
Wed 3/188:25 pm
SDQ
-
BUF
1 stop14h 32m
Delta
Deal found 1/25$323
This JetBlue deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:30 pm
BUF
-
SDQ
1 stop6h 25m
JetBlue
Fri 3/138:56 pm
SDQ
-
BUF
1 stop12h 08m
JetBlue
Deal found 1/25$342
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:00 am
BUF
-
SDQ
1 stop16h 53m
Delta
Tue 3/176:57 am
SDQ
-
BUF
1 stop16h 16m
Delta
Deal found 1/25$360
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1011:51 am
BUF
-
SDQ
1 stop6h 23m
Delta
Sun 2/153:42 pm
SDQ
-
BUF
1 stop8h 44m
Delta
Deal found 1/27$365
This JetBlue deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:30 pm
BUF
-
SDQ
1 stop6h 25m
JetBlue
Thu 3/127:59 pm
SDQ
-
BUF
1 stop13h 05m
JetBlue
Deal found 1/25$366
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:55 am
BUF
-
SDQ
2 stops13h 58m
American Airlines
Tue 3/176:00 am
SDQ
-
BUF
2 stops17h 38m
American Airlines
Deal found 1/25$370
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:00 am
BUF
-
SDQ
2 stops15h 46m
United Airlines
Thu 3/125:00 am
SDQ
-
BUF
2 stops18h 42m
United Airlines
Deal found 1/25$385
This JetBlue deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:30 pm
BUF
-
SDQ
1 stop6h 25m
JetBlue
Sat 3/148:56 pm
SDQ
-
BUF
1 stop12h 06m
JetBlue
Deal found 1/25$390
This JetBlue deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:30 pm
BUF
-
SDQ
1 stop6h 25m
JetBlue
Sun 3/159:05 pm
SDQ
-
BUF
1 stop11h 59m
JetBlue
Deal found 1/25$392
This Travelocity deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/228:45 pm
BUF
-
SDQ
1 stop12h 08m
Multiple Airlines
Sun 3/110:46 am
SDQ
-
BUF
1 stop25h 03m
Multiple Airlines
Deal found 1/26$396
This Rumbo deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/810:35 am
BUF
-
SDQ
1 stop8h 55m
JetBlue
Sun 3/159:05 pm
SDQ
-
BUF
1 stop11h 59m
JetBlue
Deal found 1/25$403

Find flight deals from Buffalo to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$319
(American Airlines)

One-way from

$146
(American Airlines)

Popular in

February

Cheapest in

March

Average price

$604
Provider with most accurate pricing for Buffalo-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Santo Domingo Las Americas flights.
Search Deals
From Buffalo to Santo Domingo Las Americas
Search Deals
One-way flight from Buffalo to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($67 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Buffalo

Fly to

Santo Domingo

Route

Depart

Return

Price

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Thu 3/5

7:00 am-12:32 am

1 stop16h 32m

Santo Domingo Las Americas

Wed 3/18

8:25 pm-10:57 am

1 stop14h 32m

$323

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 3/10

7:00 am-6:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Wed 3/18

8:25 pm-10:57 am

1 stop14h 32m

$323

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 3/11

7:00 am-11:53 pm

1 stop16h 53m

Santo Domingo Las Americas

Wed 3/18

8:25 pm-9:42 am

1 stop13h 17m

$323

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 3/9

11:37 am-11:53 pm

1 stop12h 16m

Santo Domingo Las Americas

Wed 3/18

8:25 pm-10:57 am

1 stop14h 32m

$323

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 3/9

7:30 pm-1:55 am

1 stop6h 25m

Santo Domingo Las Americas

Fri 3/13

8:56 pm-9:04 am

1 stop12h 08m

$342

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Thu 3/5

7:30 pm-2:55 am

1 stop6h 25m

Santo Domingo Las Americas

Thu 3/12

7:59 pm-9:04 am

1 stop13h 05m

$342

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 3/10

7:30 pm-1:55 am

1 stop6h 25m

Santo Domingo Las Americas

Tue 3/17

8:56 pm-9:04 am

1 stop12h 08m

$342

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Mon 3/9

7:30 pm-1:55 am

1 stop6h 25m

Santo Domingo Las Americas

Thu 3/12

7:59 pm-9:04 am

1 stop13h 05m

$342

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Wed 3/11

2:59 pm-11:53 pm

1 stop8h 54m

Santo Domingo Las Americas

Tue 3/17

2:35 pm-9:50 am

2 stops19h 15m

$342

BuffaloSanto Domingo

BUF - SDQ

BUFSDQ

Buffalo

Tue 3/10

10:35 am-7:30 pm

1 stop8h 55m

Santo Domingo Las Americas

Fri 3/13

8:56 pm-9:04 am

1 stop12h 08m

$342

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 22 results
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Compare providers for flights from Buffalo to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Santo Domingo in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Santo Domingo

What is the cheapest month to book a flight from Buffalo to Santo Domingo?

Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated January 28, 2026.
Peruse reviews from past customers who have flown with JetBlue from Buffalo to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
JetBlue
7.2
Good
2,889 reviews

Overall

7.2

Food

6.6

Comfort

7.5

Crew

8.0

Boarding

7.4

Entertainment

7.2

Reviews

1 / 20
10.0
Excellent

JACK,Sep 2025

JFK - MSY

I liked the professional services of the crew. Keep up the good work.
JetBlue
7.2
Good
2,889 reviews
JetBlue
7.2
Good
2,889 reviews

Overall

7.2

Food

6.6

Comfort

7.5

Crew

8.0

Boarding

7.4

Entertainment

7.2

Reviews

1 / 20
10.0
Excellent

JACK,Sep 2025

JFK - MSY

I liked the professional services of the crew. Keep up the good work.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Santo Domingo?

    For as low as $342, Delta can have you in Santo Domingo from Buffalo in 6h 25m. The distance between Buffalo and Santo Domingo is about 1773 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Buffalo to Santo Domingo round-trip?

    Currently priced at $325, JetBlue will fly you from Buffalo to Santo Domingo and back. In addition to JetBlue, many other airlines offer competitively priced options for your trip. You may be able to fly from Buffalo to Santo Domingo for 38% less than the average price by searching for this airline.

  • Can I find deals for flights from Buffalo to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santo Domingo.

  • Can I find deals for business class flights from Buffalo to Santo Domingo?

    Yes. Cheapflights offers flight deals from Buffalo to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Santo Domingo?

    Currently, March is the cheapest month in which you can book a flight from Buffalo to Santo Domingo (average of $197). Flying from Buffalo to Santo Domingo in June is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for Buffalo to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Buffalo to Santo Domingo

Discover the top airline that operate flights from Buffalo to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$325Average$509FlexibilityNo cancel feeOn-time62%

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