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$320+ Cheap flights from Santo Domingo (SDQ) to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/19. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — BUF
Jul 14 — Jul 211
Tue 7/14
Tue 7/21
1 adult, Economy
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Cheap flight deals from Santo Domingo to Buffalo

Cheapest flights from Santo Domingo to Buffalo
Explore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 14, 2026.

This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:18 pm
SDQ
-
BUF
1 stop7h 19m
United Airlines
Tue 11/106:00 am
BUF
-
SDQ
1 stop16h 46m
United Airlines
Deal found 6/13$420
This JetBlue deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:25 pm
SDQ
-
BUF
1 stop10h 33m
JetBlue
Tue 8/189:15 am
BUF
-
SDQ
1 stop12h 22m
JetBlue
Deal found 6/10$631
This JetBlue deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:40 pm
SDQ
-
BUF
1 stop12h 12m
JetBlue
Tue 8/49:15 am
BUF
-
SDQ
1 stop10h 53m
JetBlue
Deal found 6/13$667
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:20 pm
SDQ
-
BUF
2 stops18h 28m
United Airlines
Tue 8/185:58 pm
BUF
-
SDQ
2 stops20h 12m
United Airlines
Deal found 6/10$734
This SmartFares deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:10 pm
SDQ
-
BUF
1 stop13h 17m
JetBlue
Fri 11/207:20 am
BUF
-
SDQ
1 stop23h 42m
JetBlue
Deal found 6/13$744
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:23 pm
SDQ
-
BUF
2 stops17h 39m
American Airlines
Fri 11/207:12 pm
BUF
-
SDQ
2 stops16h 00m
American Airlines
Deal found 6/13$796
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:00 am
SDQ
-
BUF
2 stops17h 59m
United Airlines
Tue 8/46:00 am
BUF
-
SDQ
1 stop8h 10m
United Airlines
Deal found 6/13$924

Find flight deals from Santo Domingo to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$420
(United Airlines)

One-way from

$217
(Delta)

Popular in

December

Cheapest in

January

Average price

$491
Provider with most accurate pricing for Santo Domingo Las Americas-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santo Domingo Las Americas-Buffalo flights.
Search Deals
From Santo Domingo Las Americas to Buffalo
Search Deals
One-way flight from Santo Domingo Las Americas to Buffalo
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($96 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($56 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2026.
Use the filters below to find and compare flights from Santo Domingo to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 11/6

4:18 pm-10:37 pm

1 stop7h 19m

Buffalo

Tue 11/10

6:00 am-11:46 pm

1 stop16h 46m

$420
Quickest round-trip

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 8/14

12:25 pm-10:58 pm

1 stop10h 33m

Buffalo

Tue 8/18

9:15 am-9:37 pm

1 stop12h 22m

$631

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Tue 7/28

7:40 pm-7:52 am

1 stop12h 12m

Buffalo

Tue 8/4

9:15 am-8:08 pm

1 stop10h 53m

$667

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 8/14

3:20 pm-9:48 am

2 stops18h 28m

Buffalo

Tue 8/18

5:58 pm-2:10 pm

2 stops20h 12m

$734

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Thu 11/5

8:10 pm-8:27 am

1 stop13h 17m

Buffalo

Fri 11/20

7:20 am-8:02 am

1 stop23h 42m

$744

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Tue 7/28

6:00 am-11:59 pm

2 stops17h 59m

Buffalo

Tue 8/4

6:00 am-2:10 pm

1 stop8h 10m

$924
Cheapest one-way

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Sun 7/19

10:27 am-11:53 pm

2 stops13h 26m

$363
Quickest one-way

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Sun 7/19

4:08 am-2:59 pm

1 stop10h 51m

$394

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Sun 7/19

6:00 am-9:51 am

2 stops27h 51m

$401

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Sun 7/26

3:35 pm-1:53 pm

3 stops22h 18m

$440

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Santo Domingo-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santo Domingo-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santo Domingo to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Buffalo

How much does it cost to fly round-trip from Santo Domingo to Buffalo?

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santo Domingo to Buffalo?

    Departing from Santo Domingo to Buffalo will take you 7h 19m. The distance between Santo Domingo and Buffalo is about 1773 mi.

  • Can I find deals for flights from Santo Domingo to Buffalo that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Buffalo.

  • Can I find deals for business class flights from Santo Domingo to Buffalo?

    Yes. Cheapflights offers flight deals from Santo Domingo to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Amherst
Batavia
Williamsville
Orchard Park
Eden

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