$245+ Cheap flights from Santo Domingo (SDQ) to Buffalo (BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — BUF
Aug 25 — Sep 11
Round-trip
1 adult, Economy
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Find cheap flights from Santo Domingo to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santo Domingo to Buffalo
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Best
Last-minute
One-way
Cheapest flights from Santo Domingo to BuffaloExplore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 26, 2026.
Explore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 26, 2026.
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:53 pm
SDQ
- BUF
2 stops9h 00m
Delta
Sun 10/46:05 am
BUF
- SDQ
1 stop7h 22m
Delta
Deal found 7/21![Delta logo]()
$446
This JetBlue deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:29 pm
SDQ
- BUF
1 stop8h 27m
JetBlue
Sun 10/47:00 am
BUF
- SDQ
1 stop7h 49m
JetBlue
Deal found 7/22![JetBlue logo]()
$465
This JetBlue deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:29 pm
SDQ
- BUF
1 stop8h 27m
JetBlue
Sat 10/37:00 am
BUF
- SDQ
1 stop8h 25m
JetBlue
Deal found 7/24![JetBlue logo]()
$536
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am
SDQ
- BUF
1 stop9h 10m
United Airlines
Sat 10/35:45 pm
BUF
- SDQ
2 stops18h 10m
United Airlines
Deal found 7/21![United Airlines logo]()
$607
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:10 pm
SDQ
- BUF
2 stops20h 19m
United Airlines
Sun 10/410:46 am
BUF
- SDQ
2 stops27h 24m
United Airlines
Deal found 7/21![United Airlines logo]()
$616
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
SDQ
- BUF
2 stops32h 18m
United Airlines
Tue 8/256:00 am
BUF
- SDQ
1 stop16h 46m
United Airlines
Deal found 7/21![United Airlines logo]()
$655
Best flights from Santo Domingo to BuffaloDiscover carefully curated flight deals from Santo Domingo to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 26, 2026.
Discover carefully curated flight deals from Santo Domingo to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 26, 2026.
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:53 pm
SDQ
- BUF
2 stops9h 00m
Delta
Sun 10/46:05 am
BUF
- SDQ
1 stop7h 22m
Delta
Deal found 7/21![Delta logo]()
$446
This JetBlue deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:29 pm
SDQ
- BUF
1 stop8h 27m
JetBlue
Sun 10/47:00 am
BUF
- SDQ
1 stop7h 49m
JetBlue
Deal found 7/24![JetBlue logo]()
$477
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am
SDQ
- BUF
1 stop9h 10m
United Airlines
Sat 10/35:45 pm
BUF
- SDQ
2 stops18h 10m
United Airlines
Deal found 7/21![United Airlines logo]()
$607
This JetBlue deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:29 pm
SDQ
- BUF
1 stop8h 27m
JetBlue
Sat 10/36:00 am
BUF
- SDQ
1 stop8h 26m
JetBlue
Deal found 7/22![JetBlue logo]()
$529
Last-minute flights from Santo Domingo to BuffaloDiscover last-minute flight deals from Santo Domingo to Buffalo. Data last updated July 26, 2026 and is based on user searches.
Discover last-minute flight deals from Santo Domingo to Buffalo. Data last updated July 26, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 am
SDQ
- BUF
2 stops32h 18m
United Airlines
Tue 8/256:00 am
BUF
- SDQ
1 stop16h 46m
United Airlines
Deal found 7/21![United Airlines logo]()
$655
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:53 pm
SDQ
- BUF
1 stop9h 06m
Delta
Tue 8/257:00 am
BUF
- SDQ
1 stop11h 06m
Delta
Deal found 7/21![Delta logo]()
$690
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:53 pm
SDQ
- BUF
1 stop9h 06m
Delta
Sun 9/610:00 am
BUF
- SDQ
1 stop14h 54m
Delta
Deal found 7/25![Delta logo]()
$458
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:00 pm
SDQ
- BUF
1 stop26h 56m
American Airlines
Sun 9/66:21 am
BUF
- SDQ
2 stops12h 23m
American Airlines
Deal found 7/25![American Airlines logo]()
$836
One-way flights from Santo Domingo to BuffaloSearch for one-way flight options from Santo Domingo to Buffalo. Find affordable one-way fares based on user searches. Data last updated July 26, 2026.
Search for one-way flight options from Santo Domingo to Buffalo. Find affordable one-way fares based on user searches. Data last updated July 26, 2026.
This Delta deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:53 pm
SDQ
- BUF
2 stops9h 00m
Delta
Deal found 7/21![Delta logo]()
$245
This United Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am
SDQ
- BUF
2 stops27h 35m
United Airlines
Deal found 7/21![United Airlines logo]()
$254
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/262:53 pm
SDQ
- BUF
2 stops17h 22m
Delta
Deal found 7/23![Delta logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/43:35 pm
SDQ
- BUF
2 stops20h 46m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:53 pm
SDQ
- BUF
1 stop9h 06m
Delta
Deal found 7/23![Delta logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:02 pm
SDQ
- BUF
2 stops41h 27m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/33:30 pm
SDQ
- BUF
3 stops44h 51m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:41 pm
SDQ
- BUF
3 stops45h 48m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:01 pm
SDQ
- BUF
3 stops21h 20m
Multiple Airlines
Deal found 7/21![Multiple Airlines logo]()
$311
This Expedia deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:10 pm
SDQ
- BUF
1 stop11h 40m
JetBlue
Deal found 7/21![JetBlue logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:41 pm
SDQ
- BUF
3 stops29h 44m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:19 am
SDQ
- BUF
2 stops24h 10m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$321
Find flight deals from Santo Domingo to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $446 (Delta) |
One-way from | $245 (Delta) |
Popular in | December |
Cheapest in | January |
Average price | $525 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santo Domingo to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
Use the filters below to find and compare flights from Santo Domingo to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santo DomingoBuffalo
SDQ - BUF
SDQBUF
Santo Domingo Las Americas
Fri 10/2
2:53 pm-11:53 pm
2 stops9h 00m
Buffalo
Sun 10/4
6:05 am-1:27 pm
1 stop7h 22m
$446
Quickest round-trip
Santo DomingoBuffalo
SDQ - BUF
SDQBUF
Santo Domingo Las Americas
Fri 10/2
2:29 pm-10:56 pm
1 stop8h 27m
Buffalo
Sun 10/4
7:00 am-2:49 pm
1 stop7h 49m
$477
Santo DomingoBuffalo
SDQ - BUF
SDQBUF
Santo Domingo Las Americas
Fri 10/2
2:29 pm-10:56 pm
1 stop8h 27m
Buffalo
Sat 10/3
6:00 am-2:26 pm
1 stop8h 26m
$529
Santo DomingoBuffalo
SDQ - BUF
SDQBUF
Santo Domingo Las Americas
Fri 10/2
6:00 am-3:10 pm
1 stop9h 10m
Buffalo
Sat 10/3
5:45 pm-11:55 am
2 stops18h 10m
$607
Cheapest one-way
Santo DomingoBuffalo
SDQ - BUF
SDQBUF
Santo Domingo Las Americas
Mon 10/5
2:53 pm-11:53 pm
2 stops9h 00m
$245
Santo DomingoBuffalo
SDQ - BUF
SDQBUF
Santo Domingo Las Americas
Fri 10/2
2:53 pm-11:53 pm
2 stops9h 00m
$245
Santo DomingoBuffalo
SDQ - BUF
SDQBUF
Santo Domingo Las Americas
Tue 10/6
2:56 pm-11:59 pm
1 stop9h 03m
$245
Santo DomingoBuffalo
SDQ - BUF
SDQBUF
Santo Domingo Las Americas
Sat 10/31
7:49 pm-11:22 am
1 stop15h 33m
$245
Santo DomingoBuffalo
SDQ - BUF
SDQBUF
Santo Domingo Las Americas
Sat 10/3
6:00 am-9:35 am
2 stops27h 35m
$254
Quickest one-way
Santo DomingoBuffalo
SDQ - BUF
SDQBUF
Santo Domingo Las Americas
Fri 10/2
2:29 pm-10:56 pm
1 stop8h 27m
$255
Showing 1-10 of 14 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santo Domingo-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santo Domingo-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santo Domingo to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Santo Domingo with our price prediction graph.
SDQ-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Santo Domingo to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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