$235+ Cheap flights from Santo Domingo (SDQ) to Buffalo (BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — BUF
Oct 13 — Oct 201
Round-trip
1 adult, Economy
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Find cheap flights from Santo Domingo to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santo Domingo to Buffalo
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Cheapest flights from Santo Domingo to BuffaloExplore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
Explore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
This JetBlue deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:50 pm -
1 stop8h 09m
Tue 10/278:58 am -
1 stop7h 07m
Deal found 9/12![JetBlue logo]()
$425
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:10 pm -
2 stops19h 58m
Mon 10/265:58 pm -
2 stops18h 43m
Deal found 9/12![United Airlines logo]()
$446
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:35 pm -
1 stop15h 03m
Tue 10/276:00 am -
1 stop7h 32m
Deal found 9/9![Delta logo]()
$486
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:50 pm -
1 stop8h 09m
Mon 10/267:35 am -
1 stop7h 43m
Deal found 9/10![JetBlue logo]()
$510
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:10 pm -
2 stops19h 58m
Sun 10/410:30 am -
1 stop12h 16m
Deal found 9/8![United Airlines logo]()
$514
This JetBlue deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:51 pm -
1 stop8h 06m
Sun 10/47:00 am -
1 stop7h 49m
Deal found 9/11![JetBlue logo]()
$523
This JetBlue deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:30 pm -
1 stop12h 29m
Fri 1/82:10 pm -
1 stop9h 49m
Deal found 9/12![JetBlue logo]()
$542
Best flights from Santo Domingo to BuffaloDiscover carefully curated flight deals from Santo Domingo to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
Discover carefully curated flight deals from Santo Domingo to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
This JetBlue deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:50 pm -
1 stop8h 09m
Tue 10/278:58 am -
1 stop7h 07m
Deal found 9/12![JetBlue logo]()
$425
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:10 pm -
2 stops19h 58m
Mon 10/265:58 pm -
2 stops18h 43m
Deal found 9/12![United Airlines logo]()
$446
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:20 pm -
2 stops17h 48m
Tue 10/278:55 pm -
1 stop15h 46m
Deal found 9/12![United Airlines logo]()
$446
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:50 pm -
1 stop8h 09m
Mon 10/267:35 am -
1 stop7h 43m
Deal found 9/10![JetBlue logo]()
$510
Last-minute flights from Santo Domingo to BuffaloDiscover last-minute flight deals from Santo Domingo to Buffalo. Data last updated September 13, 2026 and is based on user searches.
Discover last-minute flight deals from Santo Domingo to Buffalo. Data last updated September 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:10 pm -
2 stops19h 58m
Sun 10/410:30 am -
1 stop12h 16m
Deal found 9/8![United Airlines logo]()
$514
This JetBlue deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:51 pm -
1 stop8h 06m
Sun 10/47:00 am -
1 stop7h 49m
Deal found 9/11![JetBlue logo]()
$523
This JetBlue deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:50 pm -
1 stop8h 09m
Tue 10/278:58 am -
1 stop7h 07m
Deal found 9/12![JetBlue logo]()
$425
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:35 pm -
1 stop15h 03m
Tue 10/276:00 am -
1 stop7h 32m
Deal found 9/9![Delta logo]()
$486
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/231:10 pm -
2 stops19h 58m
Mon 10/265:58 pm -
2 stops18h 43m
Deal found 9/12![United Airlines logo]()
$446
This JetBlue deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/233:50 pm -
1 stop8h 09m
Mon 10/267:35 am -
1 stop7h 43m
Deal found 9/10![JetBlue logo]()
$510
One-way flights from Santo Domingo to BuffaloSearch for one-way flight options from Santo Domingo to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
Search for one-way flight options from Santo Domingo to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:00 am -
2 stops28h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![United Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/153:09 pm -
2 stops22h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$250
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:57 pm -
1 stop9h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Delta logo]()
$265
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:20 pm -
2 stops27h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$270
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am -
1 stop27h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$271
This JetBlue deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/81:32 pm -
1 stop10h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![JetBlue logo]()
$272
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am -
2 stops27h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$276
Find flight deals from Santo Domingo to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $425 (JetBlue) |
One-way from | $235 (United Airlines) |
Popular in | May |
Cheapest in | January |
Average price | $524 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santo Domingo to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
Use the filters below to find and compare flights from Santo Domingo to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Mon 11/16
6:00 am-10:59 pm
1 stop17h 59m
Buffalo
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$235
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Sun 11/15
8:55 pm-10:35 am
1 stop14h 40m
Buffalo
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$265
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Mon 10/5
7:35 pm-10:38 am
1 stop15h 03m
Buffalo
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$265
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Fri 10/9
3:20 pm-7:07 pm
2 stops27h 47m
Buffalo
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$270
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Sat 10/10
6:00 am-9:55 am
1 stop27h 55m
Buffalo
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$271
Quickest round-trip
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Thu 10/8
1:32 pm-11:59 pm
1 stop10h 27m
Buffalo
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$272
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Fri 10/16
3:50 pm-11:59 pm
1 stop8h 09m
Buffalo
Tue 10/27
8:58 am-4:05 pm
1 stop7h 07m
$425
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Fri 10/23
1:10 pm-9:08 am
2 stops19h 58m
Buffalo
Mon 10/26
5:58 pm-12:41 pm
2 stops18h 43m
$446
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Fri 10/16
3:20 pm-9:08 am
2 stops17h 48m
Buffalo
Tue 10/27
8:55 pm-12:41 pm
1 stop15h 46m
$446
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Fri 10/23
3:50 pm-11:59 pm
1 stop8h 09m
Buffalo
Mon 10/26
7:35 am-3:18 pm
1 stop7h 43m
$510
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Santo Domingo-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santo Domingo-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santo Domingo to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Santo Domingo with our price prediction graph.
SDQ-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Santo Domingo to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsCheektowaga
Lockport
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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