What are the cheapest airlines flying from Santo Domingo to Buffalo round-trip?

Our cheapest airline available from Santo Domingo to Buffalo is Delta. Our recent data shows that you can find tickets from as low as $457 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $521 and $537 round-trip.

What are the cheapest airlines to fly from Santo Domingo to Buffalo one-way?

One-way options have recently been found by users for as low as $221 on Frontier. Other airlines that offer cheap prices include Delta from $245 and American Airlines from $271 one-way.

What is the cheapest month to book a flight from Santo Domingo to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Buffalo (average of $256). Flying from Santo Domingo to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Can I find deals for flights from Santo Domingo to Buffalo that include hotel bookings?

Yes. In addition to deals on Santo Domingo to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santo Domingo to Buffalo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Buffalo.

Can I find deals for business class flights from Santo Domingo to Buffalo?

Yes. Cheapflights offers flight deals from Santo Domingo to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$221+ Flights from Santo Domingo to Buffalo

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Cheap flight deals from Santo Domingo to Buffalo

Round-trip from	$457 (Delta)
One-way from	$221 (Justfly.com)

From Santo Domingo Las Americas to Buffalo

Search Deals

One-way flight from Santo Domingo Las Americas to Buffalo

Search Deals

Find flight deals from Santo Domingo to Buffalo

Cheapest flights from Santo Domingo to Buffalo
Explore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2025.

Sat 9/137:40 pmSDQ - BUF

1 stop14h 47mDelta

Sat 9/277:00 amBUF - SDQ

1 stop10h 59mDelta

Deal found 7/13

$457

Sat 9/137:00 amSDQ - BUF

2 stops15h 46mAmerican Airlines

Sat 9/277:40 amBUF - SDQ

2 stops12h 50mAmerican Airlines

Deal found 7/13

$521

Sat 9/131:10 pmSDQ - BUF

1 stop9h 01mUnited Airlines

Sat 9/277:07 amBUF - SDQ

2 stops18h 43mUnited Airlines

Deal found 7/13

$537

Fri 8/12:05 amSDQ - BUF

1 stop6h 55mJetBlue

Mon 8/183:55 pmBUF - SDQ

1 stop9h 20mJetBlue

Deal found 7/13

$637

Best flights from Santo Domingo to Buffalo
Discover carefully curated flight deals from Santo Domingo to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 14, 2025.

Sat 9/137:40 pmSDQ - BUF

1 stop14h 47mDelta

Sat 9/277:00 amBUF - SDQ

1 stop10h 59mDelta

Deal found 7/13

$457

Sat 9/137:00 amSDQ - BUF

2 stops15h 46mAmerican Airlines

Sat 9/277:40 amBUF - SDQ

2 stops12h 50mAmerican Airlines

Deal found 7/13

$521

Sat 9/131:10 pmSDQ - BUF

1 stop9h 01mUnited Airlines

Sat 9/277:07 amBUF - SDQ

2 stops18h 43mUnited Airlines

Deal found 7/13

$537

Fri 8/12:05 amSDQ - BUF

1 stop6h 55mJetBlue

Mon 8/183:55 pmBUF - SDQ

1 stop9h 20mJetBlue

Deal found 7/13

$637

Last-minute flights from Santo Domingo to Buffalo
Discover last-minute flight deals from Santo Domingo to Buffalo. Data last updated July 14, 2025 and is based on user searches.

Fri 8/12:05 amSDQ - BUF

1 stop6h 55mJetBlue

Mon 8/183:55 pmBUF - SDQ

1 stop9h 20mJetBlue

Deal found 7/13

$637

Sat 8/22:00 pmSDQ - BUF

1 stop10h 53mDelta

Mon 8/186:00 amBUF - SDQ

1 stop7h 22mDelta

Deal found 7/12

$536

Sat 8/27:20 pmSDQ - BUF

2 stops15h 38mAmerican Airlines

Mon 8/188:00 amBUF - SDQ

2 stops12h 30mAmerican Airlines

Deal found 7/12

$573

One-way flights from Santo Domingo to Buffalo
Search for one-way flight options from Santo Domingo to Buffalo. Find affordable one-way fares based on user searches. Data last updated July 14, 2025.

Wed 8/1311:58 amSDQ - BUF

1 stop28h 18mFrontier

Deal found 7/13

$221

Mon 9/226:03 amSDQ - BUF

1 stop9h 05mDelta

Deal found 7/14

$245

Tue 8/267:05 amSDQ - BUF

2 stops14h 35mAmerican Airlines

Deal found 7/12

$271

Tue 8/262:31 pmSDQ - BUF

1 stop8h 01mJetBlue

Deal found 7/12

$284

Tue 8/265:05 pmSDQ - BUF

3 stops47h 28mMultiple Airlines

Deal found 7/12

$348

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santo Domingo to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Sat 9/13

7:40 pm-10:27 am

1 stop14h 47m

Buffalo

Sat 9/27

7:00 am-5:59 pm

1 stop10h 59m

$457

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Sat 9/13

7:00 am-10:46 pm

2 stops15h 46m

Buffalo

Sat 9/27

7:40 am-8:30 pm

2 stops12h 50m

$521

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Sat 9/13

1:10 pm-10:11 pm

1 stop9h 01m

Buffalo

Sat 9/27

7:07 am-1:50 am

2 stops18h 43m

$537

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Fri 8/1

2:05 am-9:00 am

1 stop6h 55m

Buffalo

Mon 8/18

3:55 pm-1:15 am

1 stop9h 20m

$637

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Wed 8/13

11:58 am-4:16 pm

1 stop28h 18m

$221

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Mon 9/22

6:03 am-3:08 pm

1 stop9h 05m

$245

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Tue 8/26

7:05 am-9:40 pm

2 stops14h 35m

$271

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Tue 8/26

2:31 pm-10:32 pm

1 stop8h 01m

$284

Santo DomingoBuffalo

SDQ - BUF

SDQBUF

Santo Domingo Las Americas

Tue 8/26

5:05 pm-4:33 pm

3 stops47h 28m

$348

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/13

Best time to book a flight from Santo Domingo to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Santo Domingo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Buffalo

What is the cheapest time of day to fly from SDQ to BUF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santo Domingo to Buffalo as you normally would.

Reviews of airlines servicing Buffalo

Get a feel of what it's like to fly with Delta, United Airlines, and JetBlue from Santo Domingo to Buffalo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,956 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Delta

8.0

Very good

7,956 reviews

Delta

8.0

Very good

7,956 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

United Airlines

7.4

Good

8,858 reviews

Delta

8.0

Very good

7,956 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

JetBlue

7.3

Good

2,908 reviews

Delta

8.0

Very good

7,956 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,956 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Frontier

5.9

Fair

3,261 reviews

Delta

8.0

Very good

7,956 reviews

Reviews

1 / 20

10.0

Excellent

Lucy,Nov 2023

ATL - JFK

On time flights; courteous staff; efficient boarding system! Thank you!

Related info for your journey

What are the cheapest airlines flying from Santo Domingo to Buffalo round-trip?
Our cheapest airline available from Santo Domingo to Buffalo is Delta. Our recent data shows that you can find tickets from as low as $457 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $521 and $537 round-trip.
What are the cheapest airlines to fly from Santo Domingo to Buffalo one-way?
One-way options have recently been found by users for as low as $221 on Frontier. Other airlines that offer cheap prices include Delta from $245 and American Airlines from $271 one-way.
Can I find deals for flights from Santo Domingo to Buffalo that include hotel bookings?
Yes. In addition to deals on Santo Domingo to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santo Domingo to Buffalo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Buffalo.
Can I find deals for business class flights from Santo Domingo to Buffalo?
Yes. Cheapflights offers flight deals from Santo Domingo to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santo Domingo to Buffalo?
Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Buffalo (average of $256). Flying from Santo Domingo to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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$221+ Cheap flights from Santo Domingo (SDQ) to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/13. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santo Domingo to Buffalo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Santo Domingo to Buffalo

Round-trip from

One-way from

Find flight deals from Santo Domingo to Buffalo

Cheapest flights from Santo Domingo to BuffaloExplore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2025.

Explore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santo Domingo to Buffalo that are best for you.

Best time to book a flight from Santo Domingo to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Santo Domingo with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Buffalo

What is the cheapest time of day to fly from SDQ to BUF?

Find hourly flight availability from Santo Domingo to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 14, 2025.

Reviews of airlines servicing Buffalo

Get a feel of what it's like to fly with Delta, United Airlines, and JetBlue from Santo Domingo to Buffalo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Santo Domingo to Buffalo round-trip?

What are the cheapest airlines to fly from Santo Domingo to Buffalo one-way?

Can I find deals for flights from Santo Domingo to Buffalo that include hotel bookings?

How can I find direct flights from Santo Domingo to Buffalo?

Can I find deals for business class flights from Santo Domingo to Buffalo?

What is the cheapest month to book a flight from Santo Domingo to Buffalo?

Traveling to a place near Buffalo?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santo Domingo to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Santo Domingo to Buffalo
Explore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2025.