$311+ Cheap flights from Santo Domingo (SDQ) to Buffalo (BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — BUF
Nov 27 — Dec 41
Round-trip
1 adult, Economy
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Find cheap flights from Santo Domingo to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santo Domingo to Buffalo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Santo Domingo to BuffaloExplore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2026.
Explore the most affordable flight options available from Santo Domingo to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2026.
This JetBlue deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:04 pm -
1 stop9h 54m
Sat 11/287:35 am -
1 stop11h 25m
Deal found 10/24![JetBlue logo]()
$620
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:19 pm -
2 stops16h 23m
Sat 11/287:04 pm -
1 stop17h 46m
Deal found 10/24![American Airlines logo]()
$725
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
2 stops33h 10m
Sat 11/286:00 am -
2 stops30h 41m
Deal found 10/24![United Airlines logo]()
$832
This JetBlue deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/103:35 am -
1 stop6h 59m
Fri 12/187:00 am -
1 stop6h 52m
Deal found 10/27![JetBlue logo]()
$841
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:00 am -
2 stops17h 39m
Fri 12/185:00 am -
1 stop7h 46m
Deal found 10/27![American Airlines logo]()
$863
This Mytrip deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:35 pm -
3 stops29h 49m
Sat 11/289:21 pm -
2 stops22h 58m
Deal found 10/24![Multiple Airlines logo]()
$1,148
Best flights from Santo Domingo to BuffaloDiscover carefully curated flight deals from Santo Domingo to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 28, 2026.
Discover carefully curated flight deals from Santo Domingo to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 28, 2026.
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/274:18 pm -
2 stops22h 59m
Fri 1/292:52 pm -
2 stops21h 49m
Deal found 10/27![United Airlines logo]()
$609
This JetBlue deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:04 pm -
1 stop9h 54m
Sat 11/287:35 am -
1 stop11h 25m
Deal found 10/24![JetBlue logo]()
$620
Last-minute flights from Santo Domingo to BuffaloDiscover last-minute flight deals from Santo Domingo to Buffalo. Data last updated October 28, 2026 and is based on user searches.
Discover last-minute flight deals from Santo Domingo to Buffalo. Data last updated October 28, 2026 and is based on user searches.
This JetBlue deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:04 pm -
1 stop9h 54m
Sat 11/287:35 am -
1 stop11h 25m
Deal found 10/24![JetBlue logo]()
$620
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:19 pm -
2 stops16h 23m
Sat 11/287:04 pm -
1 stop17h 46m
Deal found 10/24![American Airlines logo]()
$725
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
2 stops33h 10m
Sat 11/286:00 am -
2 stops30h 41m
Deal found 10/24![United Airlines logo]()
$832
This Mytrip deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:35 pm -
3 stops29h 49m
Sat 11/289:21 pm -
2 stops22h 58m
Deal found 10/24![Multiple Airlines logo]()
$1,148
One-way flights from Santo Domingo to BuffaloSearch for one-way flight options from Santo Domingo to Buffalo. Find affordable one-way fares based on user searches. Data last updated October 28, 2026.
Search for one-way flight options from Santo Domingo to Buffalo. Find affordable one-way fares based on user searches. Data last updated October 28, 2026.
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/152:55 pm -
1 stop8h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![American Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/162:55 pm -
1 stop20h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![American Airlines logo]()
$313
This JetBlue deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:03 am -
1 stop9h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![JetBlue logo]()
$329
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:00 am -
2 stops28h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![United Airlines logo]()
$337
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
2 stops42h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![United Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/167:00 am -
2 stops16h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$452
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/174:17 pm -
2 stops17h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![American Airlines logo]()
$457
Find flight deals from Santo Domingo to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $614 (JetBlue) |
One-way from | $311 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Santo Domingo to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 28, 2026.
Use the filters below to find and compare flights from Santo Domingo to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Sun 11/15
2:55 pm-10:44 pm
1 stop8h 49m
Buffalo
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$311
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Mon 11/16
2:55 pm-10:11 am
1 stop20h 16m
Buffalo
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$313
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Mon 11/16
6:03 am-2:57 pm
1 stop9h 54m
Buffalo
Wed 12/31
12:00 am-12:30 am
Nonstop0h 00m
$329
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Wed 1/27
4:18 pm-2:17 pm
2 stops22h 59m
Buffalo
Fri 1/29
2:52 pm-1:41 pm
2 stops21h 49m
$609
Santo DomingoBuffalo
SDQ Santo Domingo Las Americas - BUF Buffalo
SDQBUF
Santo Domingo Las Americas
Sat 11/21
3:04 pm-11:58 pm
1 stop9h 54m
Buffalo
Sat 11/28
7:35 am-8:00 pm
1 stop11h 25m
$620
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Santo Domingo-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santo Domingo-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santo Domingo-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santo Domingo-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santo Domingo-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santo Domingo to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Santo Domingo with our price prediction graph.
SDQ-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Santo Domingo to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsCheektowaga
Lockport
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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